{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T18:50:09Z","timestamp":1788288609100,"version":"build-2803163510"},"reference-count":19,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2004,10,1]],"date-time":"2004-10-01T00:00:00Z","timestamp":1096588800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2004,10,1]],"date-time":"2004-10-01T00:00:00Z","timestamp":1096588800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The American Journal of Emergency Medicine"],"published-print":{"date-parts":[[2004,10]]},"DOI":"10.1016\/j.ajem.2004.07.016","type":"journal-article","created":{"date-parts":[[2004,10,30]],"date-time":"2004-10-30T14:25:44Z","timestamp":1099146344000},"page":"488-490","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":49,"title":["Appropriate use of epinephrine in anaphylaxis"],"prefix":"10.1016","volume":"22","author":[{"given":"Jessica","family":"Anchor","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Russell A.","family":"Settipane","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ajem.2004.07.016_BIB1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1136\/bmj.319.7201.1","article-title":"Managing acute anaphylaxis","volume":"319","author":"Hughes","year":"1999","journal-title":"Br Med J"},{"key":"10.1016\/j.ajem.2004.07.016_BIB2","doi-asserted-by":"crossref","first-page":"1749","DOI":"10.1001\/archinte.1995.00430160077008","article-title":"Anaphylaxis, a review of 266 cases","volume":"155","author":"Kemp","year":"1995","journal-title":"Arch Intern M"},{"key":"10.1016\/j.ajem.2004.07.016_BIB3","first-page":"S465","article-title":"Practice Parameters for Diagnosis and Management of Anaphylaxis","volume":"101","year":"1998","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.ajem.2004.07.016_BIB4","first-page":"43","article-title":"Emergency medical treatment of anaphylactic reactions","volume":"16","year":"1999","journal-title":"J Accident Emerg Med"},{"key":"10.1016\/j.ajem.2004.07.016_BIB5","series-title":"Anaphylaxis and Food Allergy in Food Allergy","first-page":"245","author":"Burks","year":"1997"},{"key":"10.1016\/j.ajem.2004.07.016_BIB6","series-title":"Classification of Idiopathic Anaphylaxis (IA) and an Algorithm for the Management of IA","first-page":"19","author":"Patterson","year":"1997"},{"key":"10.1016\/j.ajem.2004.07.016_BIB7","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/0091-6749(86)90117-X","article-title":"Biphasic and protracted anaphylaxis","volume":"78","author":"Stark","year":"1986","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.ajem.2004.07.016_BIB8","first-page":"181","article-title":"Accidental intravenous administration of 50mg of racemic adrenaline in a 2-year-old boy","volume":"12","author":"Dybvik","year":"1995","journal-title":"Eur J Anesthesiol"},{"key":"10.1016\/j.ajem.2004.07.016_BIB9","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1016\/0735-6757(89)90250-7","article-title":"Coronary artery spasm induced by intravenous epinephrine overdose","volume":"7","author":"Karch","year":"1989","journal-title":"Am J Emerg Med"},{"key":"10.1016\/j.ajem.2004.07.016_BIB10","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1001\/jama.1969.03150260095018","article-title":"Alarming reaction after intravenous administration of 30ml epinephrine","volume":"207","author":"Novey","year":"1969","journal-title":"JAMA"},{"key":"10.1016\/j.ajem.2004.07.016_BIB11","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1136\/bmj.286.6364.519","article-title":"Severe myocardial ischemia induced by intravenous adrenaline","volume":"268","author":"Horek","year":"1983","journal-title":"Br Med J"},{"key":"10.1016\/j.ajem.2004.07.016_BIB12","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/0735-6757(87)90293-2","article-title":"Intravenous epinephrine abuse","volume":"5","author":"Hall","year":"1987","journal-title":"Am J Emerg Med"},{"key":"10.1016\/j.ajem.2004.07.016_BIB13","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/0002-8703(86)90023-2","article-title":"Epinephrine-induced myocardial infarction in a patient with angiographically normal coronary arteries","volume":"111","author":"Ferry","year":"1986","journal-title":"Am Heart J"},{"key":"10.1016\/j.ajem.2004.07.016_BIB14","doi-asserted-by":"crossref","first-page":"3D","DOI":"10.1016\/0002-9149(85)91107-5","article-title":"Hypokalemia from beta-2-receptor stimulation by circulating epinephrine","volume":"56","author":"Brown","year":"1985","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.ajem.2004.07.016_BIB15","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1136\/emj.15.2.96","article-title":"Guidelines for the management of anaphylaxis in the emergency department","volume":"15","author":"Gavalas","year":"1998","journal-title":"J Accident Emerg Med"},{"key":"10.1016\/j.ajem.2004.07.016_BIB16","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1056\/NEJM199208063270603","article-title":"Fatal and near-fatal Anaphylaxis reactions to food in children and adolescents","volume":"327","author":"Sampson","year":"1992","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ajem.2004.07.016_BIB17","doi-asserted-by":"crossref","first-page":"1450","DOI":"10.1001\/jama.1988.03410100140041","article-title":"Fatal food induced anaphylaxis","volume":"260","author":"Yunginger","year":"1988","journal-title":"JAMA"},{"key":"10.1016\/j.ajem.2004.07.016_BIB18","first-page":"33","article-title":"Epinephrine absorption in children with a history of anaphylaxis","volume":"101","author":"Simons","year":"1998","journal-title":"JACI"},{"key":"10.1016\/j.ajem.2004.07.016_BIB19","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1136\/emj.15.2.89","article-title":"Therapeutic controversies in the management of acute anaphylaxis","volume":"15","author":"Brown","year":"1998","journal-title":"J Accident Emerg Med"}],"container-title":["The American Journal of Emergency Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S073567570400186X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S073567570400186X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T15:04:03Z","timestamp":1760022243000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S073567570400186X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,10]]},"references-count":19,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2004,10]]}},"alternative-id":["S073567570400186X"],"URL":"https:\/\/doi.org\/10.1016\/j.ajem.2004.07.016","relation":{},"ISSN":["0735-6757"],"issn-type":[{"value":"0735-6757","type":"print"}],"subject":[],"published":{"date-parts":[[2004,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Appropriate use of epinephrine in anaphylaxis","name":"articletitle","label":"Article Title"},{"value":"The American Journal of Emergency Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajem.2004.07.016","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"converted-article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2004 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}