{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T11:00:35Z","timestamp":1783422035258,"version":"3.54.6"},"reference-count":22,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2012,9,1]],"date-time":"2012-09-01T00:00:00Z","timestamp":1346457600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2012,9,1]],"date-time":"2012-09-01T00:00:00Z","timestamp":1346457600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2012,9,1]],"date-time":"2012-09-01T00:00:00Z","timestamp":1346457600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2012,9,1]],"date-time":"2012-09-01T00:00:00Z","timestamp":1346457600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2012,9,1]],"date-time":"2012-09-01T00:00:00Z","timestamp":1346457600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2012,9,1]],"date-time":"2012-09-01T00:00:00Z","timestamp":1346457600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2012,9,1]],"date-time":"2012-09-01T00:00:00Z","timestamp":1346457600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The American Journal of Emergency Medicine"],"published-print":{"date-parts":[[2012,9]]},"DOI":"10.1016\/j.ajem.2012.03.013","type":"journal-article","created":{"date-parts":[[2012,5,23]],"date-time":"2012-05-23T09:59:08Z","timestamp":1337767148000},"page":"1196-1201","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":26,"title":["Olanzapine in ED patients: differential effects on oxygenation in patients with alcohol intoxication"],"prefix":"10.1016","volume":"30","author":[{"given":"Michael P.","family":"Wilson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nita","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gary M.","family":"Vilke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edward M.","family":"Castillo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kai S.","family":"MacDonald","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arpi","family":"Minassian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.ajem.2012.03.013_bb0005","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/j.jemermed.2004.05.011","article-title":"Evidence-based treatment of psychiatric patients","volume":"28","author":"Zun","year":"2005","journal-title":"J Emerg Med"},{"issue":"19","key":"10.1016\/j.ajem.2012.03.013_bb0010","first-page":"233","article-title":"Agitation: what every emergency physician should know","volume":"30","author":"Vilke","year":"2009","journal-title":"Emerg Med Rep"},{"key":"10.1016\/j.ajem.2012.03.013_bb0015","first-page":"35","article-title":"Treatment of psychiatric patients in emergency settings","volume":"17","author":"Zeller","year":"2010","journal-title":"Prim Psychiatry"},{"key":"10.1016\/j.ajem.2012.03.013_bb0020","unstructured":"Macdonald KS, Wilson MP, Minassian A, Vilke GM, Becker O, Tallian K, et al. A naturalistic study of intramuscular haloperidol versus intramuscular olanzapine for the management of acute agitation. J Clin Psychopharmacol. In press."},{"key":"10.1016\/j.ajem.2012.03.013_bb0025","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/S0735-6757(97)90119-4","article-title":"Haloperidol, lorazepam, or both for psychotic agitation? A multicenter, prospective, double-blind, emergency department study","volume":"15","author":"Battaglia","year":"1997","journal-title":"Am J Emerg Med"},{"key":"10.1016\/j.ajem.2012.03.013_bb0030","article-title":"Benzodiazepines alone or in combination with antipsychotic drugs for acute psychosis","author":"Gillies","year":"2005","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.ajem.2012.03.013_bb0035","unstructured":"Zeller SL, Wilson MP. Acute treatment of agitation in schizophrenia. Invited review by Drug Discovery Today: Therapeutic Strategies, Available online 21 October 2011, ISSN 1740-6773, 10.1016\/j.ddstr.2011.09.005."},{"issue":"1","key":"10.1016\/j.ajem.2012.03.013_bb0040","first-page":"17","article-title":"Verbal de-escalation of the agitated patient: Consensus statement of the American Association for Emergency Psychiatry Project BETA De-escalation Workgroup","volume":"XIII","author":"Richmond","year":"2012","journal-title":"West JEM"},{"issue":"1","key":"10.1016\/j.ajem.2012.03.013_bb0045","first-page":"26","article-title":"The psychopharmacology of agitation: Consensus statement of the American Association for Emergency Psychiatry Project BETA Psychopharmacology Workgroup","volume":"XIII","author":"Wilson","year":"2012","journal-title":"West JEM"},{"key":"10.1016\/j.ajem.2012.03.013_bb0050","unstructured":"Wilson MP, Sloane C. Chemical restraints, physical restraints, and other demonstrations of force. In: Ethical problems in emergency medicine. J. Jesus, P. Rosen, J. Adams, A. Derse, R. Wolfe, S. Grossman, editors. Wiley-Blackwell. In press."},{"key":"10.1016\/j.ajem.2012.03.013_bb0055","unstructured":"Gault T, Gray S, Vilke GM, Wilson MP. Graded Evidence-based Medicine Summaries for the Journal of Emergency Medicine (GEMS for JEM): are oral medications as effective as intramuscular injections in the management of acute agitation? J Emerg Med. In press."},{"key":"10.1016\/j.ajem.2012.03.013_bb0060","article-title":"Potential complications of combining intramuscular olanzapine with benzodiazepines in agitated emergency department patients","author":"Wilson","year":"2010","journal-title":"J Emerg Med"},{"key":"10.1016\/j.ajem.2012.03.013_bb0065","article-title":"A comparison of the safety of olanzapine and haloperidol in combination with benzodiazepines in emergency department patients with acute agitation","author":"Wilson","year":"2011","journal-title":"J Emerg Med"},{"issue":"4","key":"10.1016\/j.ajem.2012.03.013_bb0070","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1016\/j.genhosppsych.2010.04.005","article-title":"A retrospective analysis of intramuscular haloperidol and olanzapine in the treatment of agitation in drug and alcohol-using patients","volume":"32","author":"MacDonald","year":"2010","journal-title":"Gen Hosp Psychiatry"},{"key":"10.1016\/j.ajem.2012.03.013_bb0075","unstructured":"Wilson MP, MacDonald K, Vilke GM, Ronquillo L, Feifel D. Use of intramuscular ziprasidone by ED clinicians and its effect on vital signs. National Behavioral Emergencies Conference, December 1-2, 2011; Las Vegas, Nevada."},{"issue":"2","key":"10.1016\/j.ajem.2012.03.013_bb0080","doi-asserted-by":"crossref","first-page":"147","DOI":"10.2165\/00023210-200519020-00005","article-title":"Intramuscular olanzapine: a review of its use in the management of acute agitation","volume":"19","author":"Wagstaff","year":"2005","journal-title":"CNS Drugs"},{"issue":"9","key":"10.1016\/j.ajem.2012.03.013_bb0085","doi-asserted-by":"crossref","first-page":"1207","DOI":"10.2165\/00003495-200565090-00003","article-title":"Pharmacological management of acute agitation","volume":"65","author":"Battaglia","year":"2005","journal-title":"Drugs"},{"key":"10.1016\/j.ajem.2012.03.013_bb0090","doi-asserted-by":"crossref","first-page":"219","DOI":"10.2165\/00023210-200216040-00002","article-title":"Pharmacological treatment of psychotic agitation","volume":"16","author":"Currier","year":"2002","journal-title":"CNS Drugs"},{"key":"10.1016\/j.ajem.2012.03.013_bb0095","doi-asserted-by":"crossref","first-page":"433","DOI":"10.4088\/JCP.08m04411gry","article-title":"Case reports of postmarketing adverse event experiences with olanzapine intramuscular treatment in patients with agitation","volume":"71","author":"Marder","year":"2010","journal-title":"J Clin Psychiatry"},{"key":"10.1016\/j.ajem.2012.03.013_bb0100","doi-asserted-by":"crossref","first-page":"12","DOI":"10.4088\/JCP.v66n1219c","article-title":"Hypotension secondary to the combination of intramuscular olanzapine and intramuscular lorazepam","volume":"66","author":"Zacher","year":"2005","journal-title":"J Clin Psychiatry"},{"key":"10.1016\/j.ajem.2012.03.013_bb0105","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1097\/JCP.0b013e3181db8715","article-title":"Comparison of intramuscular olanzapine, orally disintegrating olanzapine tablets, oral risperidone solution, and intramuscular haloperidol in the management of acute agitation in an acute care psychiatric ward in Taiwan","volume":"30","author":"Hsu","year":"2010","journal-title":"J Clin Psychopharmacol"},{"issue":"suppl 4","key":"10.1016\/j.ajem.2012.03.013_bb0110","first-page":"3","article-title":"Clinical pharmacodynamics and pharmacokinetics of antimanic and mood-stabilizing medications","volume":"63","author":"Keck","year":"2002","journal-title":"J Clin Psychiatry"}],"container-title":["The American Journal of Emergency Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0735675712001179?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0735675712001179?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T15:17:35Z","timestamp":1760023055000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0735675712001179"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,9]]},"references-count":22,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2012,9]]}},"alternative-id":["S0735675712001179"],"URL":"https:\/\/doi.org\/10.1016\/j.ajem.2012.03.013","relation":{},"ISSN":["0735-6757"],"issn-type":[{"value":"0735-6757","type":"print"}],"subject":[],"published":{"date-parts":[[2012,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Olanzapine in ED patients: differential effects on oxygenation in patients with alcohol intoxication","name":"articletitle","label":"Article Title"},{"value":"The American Journal of Emergency Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajem.2012.03.013","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2012 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}