{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T00:46:28Z","timestamp":1760057188120,"version":"build-2065373602"},"reference-count":49,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2013,4,1]],"date-time":"2013-04-01T00:00:00Z","timestamp":1364774400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,4,1]],"date-time":"2013-04-01T00:00:00Z","timestamp":1364774400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2013,4,1]],"date-time":"2013-04-01T00:00:00Z","timestamp":1364774400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2013,4,1]],"date-time":"2013-04-01T00:00:00Z","timestamp":1364774400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2013,4,1]],"date-time":"2013-04-01T00:00:00Z","timestamp":1364774400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2013,4,1]],"date-time":"2013-04-01T00:00:00Z","timestamp":1364774400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2013,4,1]],"date-time":"2013-04-01T00:00:00Z","timestamp":1364774400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The American Journal of Emergency Medicine"],"published-print":{"date-parts":[[2013,4]]},"DOI":"10.1016\/j.ajem.2012.11.026","type":"journal-article","created":{"date-parts":[[2013,2,4]],"date-time":"2013-02-04T16:30:42Z","timestamp":1359995442000},"page":"664-669","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["Myeloperoxidase and C-reactive protein in patients with cocaine-associated chest pain"],"prefix":"10.1016","volume":"31","author":[{"given":"Katie","family":"O'Conor","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna Marie","family":"Chang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alan H.B.","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Judd E.","family":"Hollander","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"year":"2010","series-title":"Results from the 2009 National Survey on Drug Use and Health: volume I. Summary of national findings (Office of Applied Studies, NSDUH series H-38A, HHS publication no. SMA 10-4586)","author":"Substance Abuse and Mental Health Services Administration","key":"10.1016\/j.ajem.2012.11.026_bb0005"},{"year":"2011","series-title":"Drug Abuse Warning Network, 2008: national estimates of drug-related emergency department visits. HHS publication no. SMA 11-4618","author":"Substance Abuse and Mental Health Services Administration, Center for Behavioral Health Statistics and Quality","key":"10.1016\/j.ajem.2012.11.026_bb0010"},{"year":"2010","series-title":"The DAWN report: highlights of the 2009 Drug Abuse Warning Network (DAWN) findings on drug-related emergency department visits","author":"Substance Abuse and Mental Health Services Administration, Center for Behavioral Health Statistics and Quality","key":"10.1016\/j.ajem.2012.11.026_bb0015"},{"key":"10.1016\/j.ajem.2012.11.026_bb0020","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/0002-9343(90)90484-U","article-title":"Cocaine-related medical problems: consecutive series of 233 patients","volume":"88","author":"Brody","year":"1990","journal-title":"Am J Med"},{"key":"10.1016\/j.ajem.2012.11.026_bb0025","doi-asserted-by":"crossref","first-page":"1028","DOI":"10.1016\/S0300-8932(10)70224-4","article-title":"Prevalence, clinical characteristics and risk of myocardial infarction in patients with cocaine-related chest pain","volume":"63","author":"Bosch","year":"2010","journal-title":"Rev Esp Cardiol"},{"issue":"21","key":"10.1016\/j.ajem.2012.11.026_bb0030","doi-asserted-by":"crossref","first-page":"2737","DOI":"10.1161\/01.CIR.99.21.2737","article-title":"Triggering of myocardial infarction by cocaine","volume":"99","author":"Mittleman","year":"1999","journal-title":"Circulation"},{"key":"10.1016\/j.ajem.2012.11.026_bb0035","doi-asserted-by":"crossref","first-page":"1595","DOI":"10.1056\/NEJMoa035003","article-title":"Prognostic value of myeloperoxidase in patients with chest pain","volume":"349","author":"Brennan","year":"2003","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ajem.2012.11.026_bb0040","first-page":"377","article-title":"Predictive value of myeloperoxidase to identify high risk patients admitted to the hospital with acute chest pain","volume":"89","author":"Esporcatte","year":"2007","journal-title":"Arg Bras Cardiol"},{"key":"10.1016\/j.ajem.2012.11.026_bb0045","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1111\/j.1365-2362.2010.02457.x","article-title":"Diagnostic efficacy of myeloperoxidase for the detection of acute coronary syndromes","volume":"41","author":"Sawicki","year":"2011","journal-title":"Eur J Clin Invest"},{"key":"10.1016\/j.ajem.2012.11.026_bb0050","doi-asserted-by":"crossref","first-page":"1279","DOI":"10.1016\/j.cca.2011.04.003","article-title":"Biochemical markers in acute coronary syndrome","volume":"412","author":"Ramasamy","year":"2011","journal-title":"Clin Chim Acta"},{"key":"10.1016\/j.ajem.2012.11.026_bb0055","doi-asserted-by":"crossref","first-page":"1897","DOI":"10.1161\/CIRCULATIONAHA.107.188950","article-title":"Management of cocaine-associated chest pain and myocardial infarction: a scientific statement from the American Heart Association Acute Cardiac Care Committee of the Council on Clinical Cardiology","volume":"117","author":"McCord","year":"2008","journal-title":"Circulation"},{"key":"10.1016\/j.ajem.2012.11.026_bb0060","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1186\/1747-597X-2-27","article-title":"Cocaine and thrombosis: a narrative systematic review of clinical and in-vivo studies","volume":"2","author":"Wright","year":"2007","journal-title":"Subst Abuse Treat Prev Policy"},{"key":"10.1016\/j.ajem.2012.11.026_bb0065","doi-asserted-by":"crossref","first-page":"876","DOI":"10.1161\/01.CIR.88.3.876","article-title":"Platelets adhesion and aggregation: activation of human platelets by cocaine","volume":"88","author":"Kugelmass","year":"1993","journal-title":"Circulation"},{"key":"10.1016\/j.ajem.2012.11.026_bb0070","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1016\/j.annemergmed.2006.01.032","article-title":"Prospective validation of the Thrombolysis in Myocardial Infarction risk score in the emergency department chest pain population","volume":"48","author":"Chase","year":"2006","journal-title":"Ann Emerg Med"},{"key":"10.1016\/j.ajem.2012.11.026_bb0075","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.annemergmed.2008.11.023","article-title":"Interrater reliability and accuracy of clinicians and trained research assistants performing prospective data collection in emergency department patients with potential acute coronary syndrome","volume":"54","author":"Cruz","year":"2009","journal-title":"Ann Emerg Med"},{"key":"10.1016\/j.ajem.2012.11.026_bb0080","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1016\/j.ajem.2009.03.019","article-title":"The effect of physician risk tolerance and the presence of an observation unit on decision making for ED patients with chest pain","volume":"27","author":"Pines","year":"2010","journal-title":"Am J Emerg Med"},{"key":"10.1016\/j.ajem.2012.11.026_bb0085","doi-asserted-by":"crossref","first-page":"1331","DOI":"10.1197\/j.aem.2004.08.033","article-title":"Standardized reporting guidelines for studies evaluating risk stratification of ED patients with potential acute coronary syndromes","volume":"11","author":"Hollander","year":"2004","journal-title":"Acad Emerg Med"},{"key":"10.1016\/j.ajem.2012.11.026_bb0090","doi-asserted-by":"crossref","first-page":"2114","DOI":"10.1016\/S0735-1097(01)01702-8","volume":"38","author":"Cannon","year":"2001","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.ajem.2012.11.026_bb0095","doi-asserted-by":"crossref","first-page":"2999","DOI":"10.1093\/eurheartj\/ehr236","volume":"32","author":"Hamm","year":"2011","journal-title":"Eur Heart J"},{"key":"10.1016\/j.ajem.2012.11.026_bb0100","doi-asserted-by":"crossref","first-page":"2525","DOI":"10.1093\/eurheartj\/ehm355","article-title":"Universal definition of myocardial infarction","volume":"28","author":"Thygesen","year":"2007","journal-title":"Eur Heart J"},{"key":"10.1016\/j.ajem.2012.11.026_bb0105","doi-asserted-by":"crossref","first-page":"1366","DOI":"10.1016\/S0735-1097(02)02336-7","volume":"40","author":"Braunwald","year":"2002","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.ajem.2012.11.026_bb0110","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1001\/jama.284.7.835","article-title":"The TIMI risk score for unstable angina and non-ST elevation MI: a method for prognostication and therapeutic decision making","volume":"284","author":"Antman","year":"2000","journal-title":"JAMA"},{"key":"10.1016\/j.ajem.2012.11.026_bb0115","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.cca.2007.02.028","article-title":"New biochemical markers: from bench to bedside","volume":"381","author":"Zaninotto","year":"2007","journal-title":"Clin Chim Acta"},{"key":"10.1016\/j.ajem.2012.11.026_bb0120","doi-asserted-by":"crossref","first-page":"2001","DOI":"10.1016\/j.jacc.2007.03.010","article-title":"Appraisal of myeloperoxidase for evaluation of patients with suspected acute coronary syndromes","volume":"49","author":"Morrow","year":"2007","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.ajem.2012.11.026_bb0125","doi-asserted-by":"crossref","first-page":"1163","DOI":"10.1056\/NEJM200004203421603","article-title":"Missed diagnosis of acute cardiac ischemia in the emergency department","volume":"342","author":"Pope","year":"2000","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ajem.2012.11.026_bb0130","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/j.ijcard.2010.08.015","article-title":"Diagnostic value of MPO plasma levels in patients admitted for suspected myocardial infarction","volume":"153","author":"Rudolph","year":"2011","journal-title":"Int J Cardiol"},{"key":"10.1016\/j.ajem.2012.11.026_bb0135","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1001\/jama.284.1.60","article-title":"Effect of a community intervention on patient delay and emergency medical service use in acute coronary heart disease: the Rapid Early Action for Coronary Treatment (REACT) Trial","volume":"284","author":"Luepker","year":"2000","journal-title":"JAMA"},{"key":"10.1016\/j.ajem.2012.11.026_bb0140","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1016\/j.ahj.2011.08.017","article-title":"Myeloperoxidase in the diagnosis of acute coronary syndromes: the importance of spectrum","volume":"162","author":"Peacock","year":"2011","journal-title":"Am Heart J"},{"key":"10.1016\/j.ajem.2012.11.026_bb0145","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1373\/clinchem.2011.172940","article-title":"Markers of plaque instability in the early diagnosis and risk stratification of acute myocardial infarction","volume":"58","author":"Schaub","year":"2011","journal-title":"Clin Chem"},{"key":"10.1016\/j.ajem.2012.11.026_bb0150","doi-asserted-by":"crossref","first-page":"2654","DOI":"10.1016\/j.jacc.2011.08.055","article-title":"High-sensitivity C-reactive protein is within normal levels at the very onset of first ST-segment elevation acute myocardial infarction in 41% of cases","volume":"58","author":"Cristell","year":"2011","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.ajem.2012.11.026_bb0155","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1865-1380-4-37","article-title":"Value of high-sensitivity C-reactive protein in low risk chest pain observation unit patients","volume":"4","author":"Diercks","year":"2011","journal-title":"Int J Emerg Med"},{"key":"10.1016\/j.ajem.2012.11.026_bb0160","doi-asserted-by":"crossref","first-page":"1993","DOI":"10.1016\/j.jacc.2007.02.040","article-title":"Plasma concentrations of myeloperoxidase predict mortality after myocardial infarction","volume":"49","author":"Mocatta","year":"2007","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.ajem.2012.11.026_bb0165","doi-asserted-by":"crossref","first-page":"1800","DOI":"10.1373\/clinchem.2007.087957","article-title":"Clinical application of C-reactive protein across the spectrum of acute coronary syndromes","volume":"53","author":"Scirica","year":"2007","journal-title":"Clin Chem"},{"key":"10.1016\/j.ajem.2012.11.026_bb0170","doi-asserted-by":"crossref","first-page":"1096","DOI":"10.1093\/eurheartj\/ehn071","article-title":"Concurrent evaluation of novel cardiac biomarkers in acute coronary syndrome: myeloperoxidase and soluble CD40 ligand and the risk of recurrent ischaemic events in TACTICS-TIMI 18","volume":"29","author":"Morrow","year":"2008","journal-title":"Eur Heart J"},{"key":"10.1016\/j.ajem.2012.11.026_bb0175","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1177\/0003319711406502","article-title":"High-sensitivity C-reactive protein is a predictor of in-hospital cardiac events in acute myocardial infarction independently of GRACE risk score","volume":"63","author":"Raposeiras-Roubin","year":"2012","journal-title":"Angiology"},{"key":"10.1016\/j.ajem.2012.11.026_bb0180","doi-asserted-by":"crossref","first-page":"1535","DOI":"10.1016\/S0735-1097(00)00581-7","article-title":"Predictive value of C-reactive protein and troponin T in patients with unstable angina: a comparative analysis","volume":"35","author":"Heeschen","year":"2000","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.ajem.2012.11.026_bb0185","doi-asserted-by":"crossref","first-page":"1460","DOI":"10.1016\/S0735-1097(98)00136-3","article-title":"C-reactive protein is a potent predictor of mortality independently of and in combination with troponin T in acute coronary syndromes: a TIMI 11A substudy","volume":"31","author":"Morrow","year":"1998","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.ajem.2012.11.026_bb0190","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/j.jacc.2007.03.033","article-title":"Serum myeloperoxidase levels are associated with the future risk of coronary artery disease in apparently healthy individuals: the EPIC-Norfolk Prospective Population Study","volume":"50","author":"Meuwese","year":"2007","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.ajem.2012.11.026_bb0195","doi-asserted-by":"crossref","first-page":"1102","DOI":"10.1016\/j.jacc.2009.11.050","article-title":"Myeloperoxidase and C-reactive protein have combined utility for long-term prediction of cardiovascular mortality after coronary angiography","volume":"55","author":"Heslop","year":"2010","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.ajem.2012.11.026_bb0200","doi-asserted-by":"crossref","first-page":"2136","DOI":"10.1001\/jama.286.17.2136","article-title":"Association between myeloperoxidase levels and risk of coronary artery disease","volume":"286","author":"Zhang","year":"2001","journal-title":"JAMA"},{"key":"10.1016\/j.ajem.2012.11.026_bb0205","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1373\/clinchem.2010.158014","article-title":"Myeloperoxidase improves risk stratification in patients with ischemia and normal cardiac troponin I concentrations","volume":"57","author":"Apple","year":"2011","journal-title":"Clin Chem"},{"key":"10.1016\/j.ajem.2012.11.026_bb0210","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1553-2712.2010.00955.x","article-title":"Relationship between cocaine use and coronary artery disease in patients with symptoms consistent with an acute coronary syndrome","volume":"18","author":"Chang","year":"2011","journal-title":"Acad Emerg Med"},{"key":"10.1016\/j.ajem.2012.11.026_bb0215","doi-asserted-by":"crossref","first-page":"2408","DOI":"10.1161\/CIRCULATIONAHA.109.192278","article-title":"Criteria for the evaluation of novel markers of cardiovascular risk: a scientific statement from the American Heart Association","volume":"119","author":"Hlatky","year":"2009","journal-title":"Circulation"},{"key":"10.1016\/j.ajem.2012.11.026_bb0220","doi-asserted-by":"crossref","first-page":"1587","DOI":"10.1056\/NEJMp038136","article-title":"Novel risk markers and clinical practice","volume":"349","author":"Manolio","year":"2003","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ajem.2012.11.026_bb0225","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1161\/CIRCULATIONAHA.106.683110","article-title":"Benchmarks for the assessment of novel cardiovascular biomarkers","volume":"115","author":"Morrow","year":"2007","journal-title":"Circulation"},{"issue":"3","key":"10.1016\/j.ajem.2012.11.026_bb0230","article-title":"Self-reported cocaine use, emergency physician testing and outcomes in suspected acute coronary syndromes: a nested matched case-control study","volume":"2","author":"Wang","year":"2012","journal-title":"BMJ"},{"key":"10.1016\/j.ajem.2012.11.026_bb0235","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1373\/clinchem.2010.155879","article-title":"Determining decision limits for new biomarkers: clinical and statistical considerations","volume":"57","author":"Morrow","year":"2011","journal-title":"Clin Chem"},{"key":"10.1016\/j.ajem.2012.11.026_bb0240","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1373\/clinchem.2006.084194","article-title":"National Academy of Clinical Biochemistry laboratory medicine practice guidelines: clinical characteristics and utilization of biochemical markers in acute coronary syndromes","volume":"53","author":"Morrow","year":"2007","journal-title":"Clin Chem"},{"key":"10.1016\/j.ajem.2012.11.026_bb0245","doi-asserted-by":"crossref","first-page":"1076","DOI":"10.1373\/clinchem.2007.101568","article-title":"Effect of collection tube type and preanalytical handling on myeloperoxidase concentrations","volume":"54","author":"Shih","year":"2008","journal-title":"Clin Chem"}],"container-title":["The American Journal of Emergency Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0735675712006079?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0735675712006079?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T15:20:23Z","timestamp":1760023223000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0735675712006079"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,4]]},"references-count":49,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2013,4]]}},"alternative-id":["S0735675712006079"],"URL":"https:\/\/doi.org\/10.1016\/j.ajem.2012.11.026","relation":{},"ISSN":["0735-6757"],"issn-type":[{"type":"print","value":"0735-6757"}],"subject":[],"published":{"date-parts":[[2013,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Myeloperoxidase and C-reactive protein in patients with cocaine-associated chest pain","name":"articletitle","label":"Article Title"},{"value":"The American Journal of Emergency Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajem.2012.11.026","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}