{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T11:32:30Z","timestamp":1792409550579,"version":"4.4.0"},"reference-count":15,"publisher":"Elsevier BV","issue":"9","license":[{"start":{"date-parts":[[2013,9,1]],"date-time":"2013-09-01T00:00:00Z","timestamp":1377993600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,9,1]],"date-time":"2013-09-01T00:00:00Z","timestamp":1377993600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The American Journal of Emergency Medicine"],"published-print":{"date-parts":[[2013,9]]},"DOI":"10.1016\/j.ajem.2013.06.043","type":"journal-article","created":{"date-parts":[[2013,7,30]],"date-time":"2013-07-30T10:31:02Z","timestamp":1375180262000},"page":"1389-1392","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":102,"title":["A new and rapid method for epistaxis treatment using injectable form of tranexamic acid topically: a randomized controlled trial"],"prefix":"10.1016","volume":"31","author":[{"given":"Reza","family":"Zahed","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Payman","family":"Moharamzadeh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saeid","family":"AlizadehArasi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asghar","family":"Ghasemi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Morteza","family":"Saeedi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.ajem.2013.06.043_bb0005","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1016\/j.joms.2005.11.031","article-title":"Epistaxis: diagnosis and treatment","volume":"64","author":"Viehweg","year":"2006","journal-title":"J Oral Maxillofac Surg"},{"issue":"3","key":"10.1016\/j.ajem.2013.06.043_bb0010","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1288\/00005537-198603000-00008","article-title":"Anterior epistaxis: a new nasal tampon for fast, effective control","volume":"96","author":"Doyle","year":"1986","journal-title":"Laryngoscope"},{"issue":"3","key":"10.1016\/j.ajem.2013.06.043_bb0015","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1111\/j.1365-2273.1977.tb01365.x","article-title":"Epistaxis","volume":"2","author":"Stell","year":"1977","journal-title":"Clin Otolaryngol Allied Sci"},{"issue":"1","key":"10.1016\/j.ajem.2013.06.043_bb0020","first-page":"27","article-title":"Guidelines to the management of epistaxis","volume":"1","author":"Bertrand","year":"2005","journal-title":"B-ent"},{"issue":"3","key":"10.1016\/j.ajem.2013.06.043_bb0025","first-page":"453","article-title":"Toxic shock syndrome after anterior-posterior nasal packing","volume":"84","author":"Aeumjaturapat","year":"2001","journal-title":"J Med Assoc Thai"},{"key":"10.1016\/j.ajem.2013.06.043_bb0030","first-page":"CD004461","article-title":"Interventions for recurrent idiopathic epistaxis (nosebleeds) in children","volume":"1","author":"Burton","year":"2004","journal-title":"Cochrane Database Syst Rev."},{"issue":"12","key":"10.1016\/j.ajem.2013.06.043_bb0035","doi-asserted-by":"crossref","first-page":"926","DOI":"10.1056\/NEJM200109203451216","article-title":"Efficacy of unusually high doses of tranexamic acid for the treatment of epistaxis in hereditary hemorrhagic telangiectasia","volume":"345","author":"Sabb\u00e0","year":"2001","journal-title":"N Engl J Med"},{"issue":"9","key":"10.1016\/j.ajem.2013.06.043_bb0040","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1017\/S002221510007777X","article-title":"Epistaxis\u2014topical use of epsilonaminocaproic acid in its management","volume":"87","author":"Jash","year":"1973","journal-title":"J Laryngol Otol"},{"issue":"1","key":"10.1016\/j.ajem.2013.06.043_bb0045","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1111\/j.1365-2273.1988.tb00275.x","article-title":"Oral tranexamic acid in the management of epistaxis","volume":"13","author":"White","year":"2007","journal-title":"Clin Otolaryngol Allied Sci"},{"issue":"4","key":"10.1016\/j.ajem.2013.06.043_bb0050","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1159\/000276741","article-title":"Effect of local tranexamic acid gel in the treatment of epistaxis","volume":"57","author":"Tibbelin","year":"1995","journal-title":"ORL J Otorhinolaryngol Relat Spec"},{"key":"10.1016\/j.ajem.2013.06.043_bb0055","series-title":"Interpretation and uses of medical statistics","author":"Daly","year":"2000"},{"key":"10.1016\/j.ajem.2013.06.043_bb0060","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3109\/00016487409129566","article-title":"Epistaxis. A clinical study with special reference to fibrinolysis","volume":"317","author":"Petruson","year":"1974","journal-title":"Acta Otolaryngol Suppl"},{"issue":"5","key":"10.1016\/j.ajem.2013.06.043_bb0065","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1001\/archinte.161.5.767","article-title":"Intranasal tranexamic acid treatment for severe epistaxis in hereditary hemorrhagic telangiectasia","volume":"161","author":"Klepfish","year":"2001","journal-title":"Arch Intern Med"},{"issue":"1","key":"10.1016\/j.ajem.2013.06.043_bb0070","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/0005-2795(75)90216-0","article-title":"Differences in the binding to fibrin of native plasminogen and plasminogen modified by proteolytic degradation. Influence of omega-aminocarboxylic acids","volume":"393","author":"Thorsen","year":"1975","journal-title":"Biochim Biophys Acta"},{"key":"10.1016\/j.ajem.2013.06.043_bb0075","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/0304-4165(81)90312-3","article-title":"Studies on the mechanism of the antifibrinolytic action of tranexamic acid","volume":"673","author":"Hoylaerts","year":"1981","journal-title":"Biochimica et Biophysica Acta"}],"container-title":["The American Journal of Emergency Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0735675713004208?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0735675713004208?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T15:20:26Z","timestamp":1760023226000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0735675713004208"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,9]]},"references-count":15,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2013,9]]}},"alternative-id":["S0735675713004208"],"URL":"https:\/\/doi.org\/10.1016\/j.ajem.2013.06.043","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.718113793.793488267","asserted-by":"object"}]},"ISSN":["0735-6757"],"issn-type":[{"value":"0735-6757","type":"print"}],"subject":[],"published":{"date-parts":[[2013,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A new and rapid method for epistaxis treatment using injectable form of tranexamic acid topically: a randomized controlled trial","name":"articletitle","label":"Article Title"},{"value":"The American Journal of Emergency Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajem.2013.06.043","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}