{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T11:28:09Z","timestamp":1781090889680,"version":"3.54.1"},"reference-count":14,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2017,3,1]],"date-time":"2017-03-01T00:00:00Z","timestamp":1488326400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,3,1]],"date-time":"2017-03-01T00:00:00Z","timestamp":1488326400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The American Journal of Emergency Medicine"],"published-print":{"date-parts":[[2017,3]]},"DOI":"10.1016\/j.ajem.2016.09.040","type":"journal-article","created":{"date-parts":[[2016,9,23]],"date-time":"2016-09-23T09:15:40Z","timestamp":1474622140000},"page":"519.e1-519.e4","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":15,"title":["Dual cocaine and methamphetamine cardiovascular toxicity: rapid resolution with labetalol"],"prefix":"10.1016","volume":"35","author":[{"given":"John R.","family":"Richards","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard A.","family":"Lange","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas C.","family":"Arnold","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B. Zane","family":"Horowitz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ajem.2016.09.040_bb0005","author":"US Department of Justice"},{"key":"10.1016\/j.ajem.2016.09.040_bb0010","doi-asserted-by":"crossref","first-page":"345","DOI":"10.3109\/15563650.2016.1142090","article-title":"Treatment of cocaine cardiovascular toxicity: a systematic review","volume":"54","author":"Richards","year":"2016","journal-title":"Clin Toxicol (Phila)"},{"key":"10.1016\/j.ajem.2016.09.040_bb0015","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.drugalcdep.2015.01.040","article-title":"Treatment of toxicity from amphetamines, related derivatives, and analogues: a systematic clinical review","volume":"150","author":"Richards","year":"2015","journal-title":"Drug Alcohol Depend"},{"key":"10.1016\/j.ajem.2016.09.040_bb0020","doi-asserted-by":"crossref","first-page":"1897","DOI":"10.1161\/CIRCULATIONAHA.107.188950","article-title":"Management of cocaine-associated chest pain and myocardial infarction: a scientific statement from the American Heart Association acute cardiac Care Committee of the Council on clinical cardiology","volume":"117","author":"McCord","year":"2008","journal-title":"Circulation"},{"key":"10.1016\/j.ajem.2016.09.040_bb0025","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1016\/j.annemergmed.2007.08.020","article-title":"Cocaine, myocardial infarction, and beta-blockers: time to rethink the equation?","volume":"51","author":"Freeman","year":"2008","journal-title":"Ann Emerg Med"},{"key":"10.1016\/j.ajem.2016.09.040_bb0030","doi-asserted-by":"crossref","first-page":"1269","DOI":"10.1002\/phar.1486","article-title":"Controversial therapeutics: the \u03b2 -adrenergic antagonist and cocaine-associated cardiovascular complications dilemma","volume":"34","author":"Schurr","year":"2014","journal-title":"Pharmacotherapy"},{"key":"10.1016\/j.ajem.2016.09.040_bb0035","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1016\/j.ccc.2012.07.003","article-title":"Cocaine intoxication","volume":"28","author":"Zimmerman","year":"2012","journal-title":"Crit Care Clin"},{"key":"10.1016\/j.ajem.2016.09.040_bb0040","doi-asserted-by":"crossref","first-page":"688","DOI":"10.1136\/heart.83.6.688","article-title":"Cocaine activates platelets and increases the formation of circulating platelet containing microaggregates in humans","volume":"83","author":"Heesch","year":"2000","journal-title":"Heart"},{"key":"10.1016\/j.ajem.2016.09.040_bb0045","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1146\/annurev.pharmtox.47.120505.105140","article-title":"New insights into the mechanism of action of amphetamines","volume":"47","author":"Fleckenstein","year":"2007","journal-title":"Annu Rev Pharmacol Toxicol"},{"key":"10.1016\/j.ajem.2016.09.040_bb0050","doi-asserted-by":"crossref","first-page":"1177","DOI":"10.1592\/phco.24.13.1177.38089","article-title":"Paradoxical reactions to benzodiazepines: literature review and treatment options","volume":"24","author":"Mancuso","year":"2004","journal-title":"Pharmacotherapy"},{"key":"10.1016\/j.ajem.2016.09.040_bb0055","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/S0196-0644(87)80038-0","article-title":"Labetalol treatment of cocaine toxicity","volume":"16","author":"Dusenberry","year":"1987","journal-title":"Ann Emerg Med"},{"key":"10.1016\/j.ajem.2016.09.040_bb0060","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1016\/S0196-0644(88)80124-0","article-title":"The use of labetalol in the management of cocaine crisis","volume":"17","author":"Gay","year":"1988","journal-title":"Ann Emerg Med"},{"key":"10.1016\/j.ajem.2016.09.040_bb0065","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1016\/0002-9343(93)90212-8","article-title":"Influence of labetalol on cocaine-induced coronary vasoconstriction in humans","volume":"94","author":"Boehrer","year":"1993","journal-title":"Am J Med"},{"key":"10.1016\/j.ajem.2016.09.040_bb0070","doi-asserted-by":"crossref","first-page":"e179","DOI":"10.1016\/j.jacc.2013.01.014","volume":"61","author":"Anderson","year":"2013","journal-title":"J Am Coll Cardiol"}],"container-title":["The American Journal of Emergency Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0735675716306180?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0735675716306180?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T15:34:07Z","timestamp":1760024047000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0735675716306180"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,3]]},"references-count":14,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2017,3]]}},"alternative-id":["S0735675716306180"],"URL":"https:\/\/doi.org\/10.1016\/j.ajem.2016.09.040","relation":{},"ISSN":["0735-6757"],"issn-type":[{"value":"0735-6757","type":"print"}],"subject":[],"published":{"date-parts":[[2017,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Dual cocaine and methamphetamine cardiovascular toxicity: rapid resolution with labetalol","name":"articletitle","label":"Article Title"},{"value":"The American Journal of Emergency Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajem.2016.09.040","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}