{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T20:56:19Z","timestamp":1760043379967,"version":"build-2065373602"},"reference-count":26,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2017,4,1]],"date-time":"2017-04-01T00:00:00Z","timestamp":1491004800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,4,1]],"date-time":"2017-04-01T00:00:00Z","timestamp":1491004800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"name":"French Society of Emergency Medicine and \u201cInstitut Upsa de la douleur","award":["2009-2010"],"award-info":[{"award-number":["2009-2010"]}]},{"DOI":"10.13039\/100005615","name":"Beth Israel Deaconess Medical Center","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100005615","id-type":"DOI","asserted-by":"publisher"}]},{"name":"H\u00f4pitaux Universitaires de Toulouse"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The American Journal of Emergency Medicine"],"published-print":{"date-parts":[[2017,4]]},"DOI":"10.1016\/j.ajem.2016.11.053","type":"journal-article","created":{"date-parts":[[2016,11,30]],"date-time":"2016-11-30T14:25:00Z","timestamp":1480515900000},"page":"531-535","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"title":["Predicting morphine related side effects in the ED: An international cohort study"],"prefix":"10.1016","volume":"35","author":[{"given":"Vincent","family":"Bounes","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B\u00e9atrice","family":"Charriton-Dadone","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4867-1474","authenticated-orcid":false,"given":"Jacques","family":"Levraut","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cyril","family":"Delangue","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fran\u00e7oise","family":"Carpentier","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"St\u00e9phanie","family":"Mary-Chalon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vanessa","family":"Houze-Cerfon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Agn\u00e8s","family":"Sommet","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charles-Henri","family":"Houze-Cerfon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Ganetsky","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ajem.2016.11.053_bb0005","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1007\/s13341-010-0019-9","article-title":"Recommandations formalis\u00e9es d'experts 2010: s\u00e9dation et analg\u00e9sie en structure d'urgence (r\u00e9actualisation de la conf\u00e9rence d'experts de la SFAR de 1999)","volume":"1","author":"Vivien","year":"2011","journal-title":"Ann Fr Med Urgence"},{"key":"10.1016\/j.ajem.2016.11.053_bb0010","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/S0733-8627(05)70111-5","article-title":"Systemic analgesia and sedation in managing orthopedic emergencies","volume":"18","author":"Ward","year":"2000","journal-title":"Emerg Med Clin North Am"},{"key":"10.1016\/j.ajem.2016.11.053_bb0015","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/S0736-4679(98)00135-8","article-title":"Procedural sedation and analgesia in the emergency department. Canadian consensus guidelines","volume":"17","author":"Innes","year":"1999","journal-title":"J Emerg Med"},{"key":"10.1016\/j.ajem.2016.11.053_bb0020","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1016\/j.annemergmed.2010.03.020","article-title":"Sufentanil is not superior to morphine for the treatment of acute traumatic pain in an emergency setting: a randomized, double-blind, out-of-hospital trial","volume":"56","author":"Bounes","year":"2010","journal-title":"Ann Emerg Med"},{"key":"10.1016\/j.ajem.2016.11.053_bb0025","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1097\/00063110-200112000-00005","article-title":"Comparison of alfentanil and morphine in the prehospital treatment of patients with acute ischaemic-type chest pain","volume":"8","author":"Silfvast","year":"2001","journal-title":"Eur J Emerg Med"},{"key":"10.1016\/j.ajem.2016.11.053_bb0030","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/j.ajem.2004.03.010","article-title":"A randomized, double blind study comparing morphine with fentanyl in prehospital analgesia","volume":"23","author":"Galinski","year":"2005","journal-title":"Am J Emerg Med"},{"key":"10.1016\/j.ajem.2016.11.053_bb0035","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1016\/j.annemergmed.2006.03.005","article-title":"Safety and efficacy of hydromorphone as an analgesic alternative to morphine in acute pain: a randomized clinical trial","volume":"48","author":"Chang","year":"2006","journal-title":"Ann Emerg Med"},{"key":"10.1016\/j.ajem.2016.11.053_bb0040","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1016\/j.ajem.2007.10.025","article-title":"Intravenous morphine titration to treat severe pain in the ED","volume":"26","author":"Lvovschi","year":"2008","journal-title":"Am J Emerg Med"},{"key":"10.1016\/j.ajem.2016.11.053_bb0045","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1016\/j.ajem.2007.04.020","article-title":"Is there an ideal morphine dose for prehospital treatment of severe acute pain? A randomized, double-blind comparison of 2 doses","volume":"26","author":"Bounes","year":"2008","journal-title":"Am J Emerg Med"},{"key":"10.1016\/j.ajem.2016.11.053_bb0050","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1111\/j.1553-2712.2009.00405.x","article-title":"Outcomes after intravenous opioids in emergency patients: a prospective cohort analysis","volume":"16","author":"O'Connor","year":"2009","journal-title":"Acad Emerg Med"},{"key":"10.1016\/j.ajem.2016.11.053_bb0055","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1111\/j.1365-2125.2009.03472.x","article-title":"Reporting rate of adverse drug reactions to the French pharmacovigilance system with three step 2 analgesic drugs: dextropropoxyphene, tramadol and codeine (in combination with paracetamol)","volume":"68","author":"Tavassoli","year":"2009","journal-title":"Br J Clin Pharmacol"},{"key":"10.1016\/j.ajem.2016.11.053_bb0060","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1016\/j.ajem.2009.12.005","article-title":"Predictors of pain relief and ADRs in patients receiving opioids in a prehospital setting","volume":"29","author":"Bounes","year":"2011","journal-title":"Am J Emerg Med"},{"key":"10.1016\/j.ajem.2016.11.053_bb0065","series-title":"Goodman and Gilman's The pharmacological Basis of Therapeutics","volume":"vol. 11","author":"Brunton","year":"2005"},{"key":"10.1016\/j.ajem.2016.11.053_bb0070","first-page":"111","article-title":"Imputation of the unexpected or toxic effects of drugs. Actualization of the method used in France","volume":"40","author":"Begaud","year":"1985","journal-title":"Therapie"},{"key":"10.1016\/j.ajem.2016.11.053_bb0075","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1111\/j.1742-6723.2011.01433.x","article-title":"Review article: prophylactic metoclopramide for patients receiving intravenous morphine in the emergency setting: a systematic review and meta-analysis of randomized controlled trials","volume":"23","author":"Simpson","year":"2011","journal-title":"Emerg Med Australas"},{"key":"10.1016\/j.ajem.2016.11.053_bb0080","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1016\/j.annemergmed.2005.03.010","article-title":"Intravenous morphine at 0.1mg\/kg is not effective for controlling severe acute pain in the majority of patients","volume":"46","author":"Bijur","year":"2005","journal-title":"Ann Emerg Med"},{"key":"10.1016\/j.ajem.2016.11.053_bb0085","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1097\/00000539-200003000-00029","article-title":"The efficacy of intravenous 0.15 versus 0.25mg\/kg intraoperative morphine for immediate postoperative analgesia after remifentanil-based anesthesia for major surgery","volume":"90","author":"Fletcher","year":"2000","journal-title":"Anesth Analg"},{"key":"10.1016\/j.ajem.2016.11.053_bb0090","doi-asserted-by":"crossref","first-page":"1079","DOI":"10.5811\/westjem.2015.10.28454","article-title":"The changing use of intravenous opioids in an emergency department","volume":"16","author":"Sutter","year":"2015","journal-title":"W J Emerg Med"},{"key":"10.1016\/j.ajem.2016.11.053_bb0095","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1136\/emj.2005.029819","article-title":"Use of a prophylactic antiemetic with morphine in acute pain: randomised controlled trial","volume":"23","author":"Bradshaw","year":"2006","journal-title":"Emerg Med J"},{"key":"10.1016\/j.ajem.2016.11.053_bb0100","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.ajem.2004.01.001","article-title":"Low-dose naloxone does not improve morphine-induced nausea, vomiting, or pruritus","volume":"23","author":"Greenwald","year":"2005","journal-title":"Am J Emerg Med"},{"key":"10.1016\/j.ajem.2016.11.053_bb0105","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1053\/ajem.2000.16293","article-title":"Prophylactic metoclopramide is unnecessary with intravenous analgesia in the ED","volume":"18","author":"Talbot-Stern","year":"2000","journal-title":"Am J Emerg Med"},{"key":"10.1016\/j.ajem.2016.11.053_bb0110","first-page":"779","article-title":"Acute pain service and multimodal therapy for postsurgical pain control: evaluation of protocol efficacy","volume":"70","author":"Moizo","year":"2004","journal-title":"Minerva Anestesiol"},{"key":"10.1016\/j.ajem.2016.11.053_bb0115","series-title":"Who Guidelines on the Pharmacological Treatment of Persisting Pain in Children with Medical Illnesses","first-page":"166","author":"Who","year":"2012"},{"key":"10.1016\/j.ajem.2016.11.053_bb0120","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1093\/bja\/aeq406","article-title":"Paracetamol and selective and non-selective non-steroidal anti-inflammatory drugs for the reduction in morphine-related side-effects after major surgery: a systematic review","volume":"106","author":"Maund","year":"2011","journal-title":"Br J Anaesth"},{"key":"10.1016\/j.ajem.2016.11.053_bb0125","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1016\/j.jcrc.2009.12.012","article-title":"Intravenous paracetamol reduced the use of opioids, extubation time, and opioid-related adverse effects after major surgery in intensive care unit","volume":"25","author":"Memis","year":"2010","journal-title":"J Crit Care"},{"key":"10.1016\/j.ajem.2016.11.053_bb0130","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1097\/00000542-200307000-00026","article-title":"Postoperative morphine consumption in the elderly patient","volume":"99","author":"Aubrun","year":"2003","journal-title":"Anesthesiology"}],"container-title":["The American Journal of Emergency Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0735675716308889?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0735675716308889?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T15:34:05Z","timestamp":1760024045000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0735675716308889"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,4]]},"references-count":26,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2017,4]]}},"alternative-id":["S0735675716308889"],"URL":"https:\/\/doi.org\/10.1016\/j.ajem.2016.11.053","relation":{},"ISSN":["0735-6757"],"issn-type":[{"type":"print","value":"0735-6757"}],"subject":[],"published":{"date-parts":[[2017,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Predicting morphine related side effects in the ED: An international cohort study","name":"articletitle","label":"Article Title"},{"value":"The American Journal of Emergency Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajem.2016.11.053","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}