{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T05:04:36Z","timestamp":1784610276238,"version":"3.55.0"},"reference-count":10,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2017,6,1]],"date-time":"2017-06-01T00:00:00Z","timestamp":1496275200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,6,1]],"date-time":"2017-06-01T00:00:00Z","timestamp":1496275200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The American Journal of Emergency Medicine"],"published-print":{"date-parts":[[2017,6]]},"DOI":"10.1016\/j.ajem.2016.12.029","type":"journal-article","created":{"date-parts":[[2016,12,12]],"date-time":"2016-12-12T15:30:38Z","timestamp":1481556638000},"page":"934.e3-934.e4","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["Septic shock without hyperlactatemia"],"prefix":"10.1016","volume":"35","author":[{"given":"Johnathan","family":"Lebaron","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert J","family":"Leonard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ajem.2016.12.029_bb0005","author":"Emmett"},{"issue":"9","key":"10.1016\/j.ajem.2016.12.029_bb0010","doi-asserted-by":"crossref","first-page":"1,29","DOI":"10.1097\/01.EEM.0000499522.28133.48","article-title":"The science of emergency medicine: humans are not yeast","volume":"38","author":"Marik","year":"2016","journal-title":"Emerg Med News"},{"key":"10.1016\/j.ajem.2016.12.029_bb0015","doi-asserted-by":"crossref","DOI":"10.1136\/bcr-2013-201015","article-title":"Inhaled \u03b2-agonist therapy and respiratory muscle fatigue as under-recognised causes of lactic acidosis","author":"Lau","year":"2013","journal-title":"BMJ Case Rep"},{"key":"10.1016\/j.ajem.2016.12.029_bb0020","author":"Gunnerson"},{"key":"10.1016\/j.ajem.2016.12.029_bb0025","doi-asserted-by":"crossref","first-page":"1637","DOI":"10.1097\/01.CCM.0000132904.35713.A7","article-title":"Early lactate clearance is associated with improved outcome in severe sepsis and septic shock","volume":"32","author":"Nguyen","year":"2004","journal-title":"Crit Care Med"},{"key":"10.1016\/j.ajem.2016.12.029_bb0030","doi-asserted-by":"crossref","first-page":"R25","DOI":"10.1186\/cc8888","article-title":"Relative hyperlactatemia and hospital mortality in critically ill patients: a retrospective multi-centre study","volume":"14","author":"Nichol","year":"2010","journal-title":"Crit Care"},{"key":"10.1016\/j.ajem.2016.12.029_bb0035","doi-asserted-by":"crossref","first-page":"1670","DOI":"10.1097\/CCM.0b013e31819fcf68","article-title":"Serum lactate is associated with mortality in severe sepsis independent of organ failure and shock","volume":"37","author":"Mikkelsen","year":"2009","journal-title":"Crit Care Med"},{"key":"10.1016\/j.ajem.2016.12.029_bb0040","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1016\/j.annemergmed.2004.12.006","article-title":"Serum lactate as a predictor of mortality in emergency department patients with infection","volume":"45","author":"Shapiro","year":"2005","journal-title":"Ann Emerg Med"},{"issue":"4","key":"10.1016\/j.ajem.2016.12.029_bb0045","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1016\/j.jcrc.2010.09.007","article-title":"Persistent sepsis-induced hypotension without hyperlactatemia: is it really septic shock?","volume":"26","author":"Hernandez","year":"2011","journal-title":"J Crit Care"},{"issue":"12","key":"10.1016\/j.ajem.2016.12.029_bb0050","doi-asserted-by":"crossref","first-page":"2616","DOI":"10.1097\/CCM.0000000000001308","article-title":"Long-term \u03b2-blocker therapy decreases blood lactate concentration in severely septic patients","volume":"43","author":"Contenti","year":"2015","journal-title":"Crit Care Med"}],"container-title":["The American Journal of Emergency Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0735675716309299?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0735675716309299?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T15:35:38Z","timestamp":1760024138000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0735675716309299"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,6]]},"references-count":10,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2017,6]]}},"alternative-id":["S0735675716309299"],"URL":"https:\/\/doi.org\/10.1016\/j.ajem.2016.12.029","relation":{},"ISSN":["0735-6757"],"issn-type":[{"value":"0735-6757","type":"print"}],"subject":[],"published":{"date-parts":[[2017,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Septic shock without hyperlactatemia","name":"articletitle","label":"Article Title"},{"value":"The American Journal of Emergency Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajem.2016.12.029","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}