{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T13:40:59Z","timestamp":1781617259354,"version":"3.54.5"},"reference-count":28,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2018,10,1]],"date-time":"2018-10-01T00:00:00Z","timestamp":1538352000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,10,1]],"date-time":"2018-10-01T00:00:00Z","timestamp":1538352000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The American Journal of Emergency Medicine"],"published-print":{"date-parts":[[2018,10]]},"DOI":"10.1016\/j.ajem.2018.01.092","type":"journal-article","created":{"date-parts":[[2018,3,1]],"date-time":"2018-03-01T06:48:47Z","timestamp":1519886927000},"page":"1789-1795","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":13,"title":["Penta-therapy for severe acute hyperlipidemic pancreatitis"],"prefix":"10.1016","volume":"36","author":[{"given":"Jian","family":"Lu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yun","family":"Xie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiang","family":"Du","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mei","family":"Kang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Jin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui","family":"Xie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruijie","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rui","family":"Tian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9555-2649","authenticated-orcid":false,"given":"Ruilan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"9","key":"10.1016\/j.ajem.2018.01.092_bb0005","first-page":"1578","article-title":"Primary hyperchylomicronemi","volume":"71","author":"Yamashita","year":"2013","journal-title":"Nihon Rinsho"},{"issue":"9","key":"10.1016\/j.ajem.2018.01.092_bb0010","doi-asserted-by":"crossref","first-page":"2969","DOI":"10.1210\/jc.2011-3213","article-title":"Evaluation and treatment of hypertriglyceridemia: an Endocrine Society clinical practice guideline. [J]. Endocrine society","volume":"97","author":"Berglund","year":"2012","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.ajem.2018.01.092_bb0015","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1016\/j.jacl.2012.08.002","article-title":"Severe hypertriglyceridemia. [J]","volume":"6","author":"Brown","year":"2012","journal-title":"J Clin Lipidol"},{"key":"10.1016\/j.ajem.2018.01.092_bb0020","first-page":"417","article-title":"Severe hypertriglyceridaemia. Treatment with plasmapheresis","volume":"32","author":"Izquierdo-Ortiz","year":"2012","journal-title":"Nefrologia"},{"issue":"11","key":"10.1016\/j.ajem.2018.01.092_bb0025","doi-asserted-by":"crossref","first-page":"2622","DOI":"10.3748\/wjg.v9.i11.2622","article-title":"Formalized therapeutic guideline for hyperlipidemic severe acute pancreatitis","volume":"9","author":"Mao","year":"2003","journal-title":"World J Gastroenterol"},{"key":"10.1016\/j.ajem.2018.01.092_bb0030","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/j.endonu.2010.12.007","article-title":"Plasmapheresis as treatment for severe hypertriglyceridemia","volume":"58","author":"Manrique Franco","year":"2011","journal-title":"Endocrinol Nutr"},{"key":"10.1016\/j.ajem.2018.01.092_bb0035","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1007\/s11255-011-9936-7","article-title":"Hemoperfusion plus continuous veno-venous hemofiltration in a pregnant woman with severe acute pancreatitis: a case report","volume":"44","author":"Tang","year":"2012","journal-title":"Int Urol Nephrol"},{"key":"10.1016\/j.ajem.2018.01.092_bb0040","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1001\/archsurg.1993.01420170122019","article-title":"A clinically based classifica- tion system for acute pancreatitis. Summary of the International Symposium on Acute pancreatitis, Atlanta, Ga, September 11 through 13, 1992","volume":"128","author":"El","year":"1993","journal-title":"Arch Surg"},{"issue":"Suppl","key":"10.1016\/j.ajem.2018.01.092_bb0045","first-page":"S15","article-title":"Guidelines for the management of acute pancreatitis","volume":"17","author":"Toouli","year":"2002","journal-title":"J Gastroenterol Hepatol"},{"key":"10.1016\/j.ajem.2018.01.092_bb0050","doi-asserted-by":"crossref","first-page":"1644","DOI":"10.1378\/chest.101.6.1644","article-title":"Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The ACCp\/SCCM Consensus Conference Committee. American College of Chest physicians\/Society of Critical Care Medicine","volume":"101","author":"Bone","year":"1992","journal-title":"Chest"},{"key":"10.1016\/j.ajem.2018.01.092_bb0055","doi-asserted-by":"crossref","first-page":"984","DOI":"10.1038\/ajg.2009.27","article-title":"Hypertriglyceridemic pancreatitis: presentation and management","volume":"104","author":"Tsuang","year":"2009","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.ajem.2018.01.092_bb0060","doi-asserted-by":"crossref","first-page":"1491","DOI":"10.1056\/NEJMoa0908821","article-title":"A step-up approach or open necrosectomy for necrotizing pancreatitis","volume":"362","author":"van Santvoort","year":"2010","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ajem.2018.01.092_bb0065","first-page":"2134","article-title":"Clinical assessment of hyperlipidemic pancreatitis","volume":"90","author":"Fortson","year":"1995","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.ajem.2018.01.092_bb0070","first-page":"1655","article-title":"Etiology of acute pancreatitis-a multi-center study in Taiwan","volume":"50","author":"Chang","year":"2003","journal-title":"Hepato-Gastroenterology"},{"key":"10.1016\/j.ajem.2018.01.092_bb0075","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1001\/2013.jamainternmed.477","article-title":"Hypertriglyceridemia and acute pancreatitis","volume":"173","author":"Murphy","year":"2013","journal-title":"JAMA Intern Med"},{"key":"10.1016\/j.ajem.2018.01.092_bb0080","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1016\/S1499-3872(11)60131-8","article-title":"Triglyceride levels and apolipoprotein E polymorphism in patients with acute pancreatitis","volume":"11","author":"Ivanova","year":"2012","journal-title":"Hepatobiliary Pancreat Dis Int"},{"key":"10.1016\/j.ajem.2018.01.092_bb0085","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1016\/j.atherosclerosis.2010.03.006","article-title":"All-cause and cardiovascular mortality in treated patients with severe hypertriglyceridaemia: a long-term prospective registry study","volume":"211","author":"Neil","year":"2010","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.ajem.2018.01.092_bb0090","doi-asserted-by":"crossref","first-page":"1345","DOI":"10.1093\/eurheartj\/ehr112","article-title":"Triglyceride-rich lipoproteins and high-density lipoprotein cholesterol in patients at high risk of cardiovascular disease: evidence and guidance for management","volume":"32","author":"MJ","year":"2011","journal-title":"Eur Heart J"},{"issue":"5","key":"10.1016\/j.ajem.2018.01.092_bb0095","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1111\/1744-9987.12300","article-title":"Continuous renal replacement therapy in successful treatment of a patient with hyperlipidemic acute pancreatitis","volume":"19","author":"Guo","year":"2015","journal-title":"Ther Apher Dial"},{"issue":"5","key":"10.1016\/j.ajem.2018.01.092_bb0100","doi-asserted-by":"crossref","first-page":"352","DOI":"10.5144\/0256-4947.2015.352","article-title":"High-volume hemofiltration plus hemoperfusion for hyperlipidemic severe acute pancreatitis: a controlled pilot study","volume":"35","author":"Sun","year":"2015","journal-title":"Ann Saudi Med"},{"issue":"9","key":"10.1016\/j.ajem.2018.01.092_bb0105","doi-asserted-by":"crossref","DOI":"10.1097\/MCG.0000000000000552","article-title":"Emergent triglyceride-lowering therapy with early high-volume hemofiltration against low-molecular-weight heparin combined with insulin in hypertriglyceridemic pancreatitis: a prospective randomized controlled trial","volume":"50","author":"He","year":"2016","journal-title":"J Clin Gastroenterol"},{"issue":"8","key":"10.1016\/j.ajem.2018.01.092_bb0110","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1016\/j.ejim.2014.08.008","article-title":"Current knowledge of hypertriglyceridemic pancreatitis","volume":"25","author":"Valdivielso","year":"2014","journal-title":"Eur J Intern Med"},{"issue":"9","key":"10.1016\/j.ajem.2018.01.092_bb0115","doi-asserted-by":"crossref","first-page":"2969","DOI":"10.1210\/jc.2011-3213","article-title":"Evaluation and treatment of hypertriglyceridemia: an Endocrine Society clinical practice guideline","volume":"97","author":"Berglund","year":"2012","journal-title":"J Clin Endocrinol Metab"},{"issue":"1","key":"10.1016\/j.ajem.2018.01.092_bb0120","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.jep.2014.05.040","article-title":"The effect of Chinese herbal medicine on non-biliogenic severe acute pancreatitis: a systematic review and meta-analysis","volume":"155","author":"Lu","year":"2014","journal-title":"J Ethnopharmacol"},{"key":"10.1016\/j.ajem.2018.01.092_bb0125","series-title":"Case Reports in Critical Care","article-title":"Hypertriglyceridemia induced pancreatitis (chylomicronemia syndrome) treated with supportive care","volume":"2014","author":"Uysal","year":"2013"},{"key":"10.1016\/j.ajem.2018.01.092_bb0130","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1111\/1744-9987.12008","article-title":"Severe hypertriglyceridemia-related acute pancreatitis","volume":"17","author":"Stefanutti","year":"2013","journal-title":"Ther Apher Dial"},{"issue":"6","key":"10.1016\/j.ajem.2018.01.092_bb0135","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1016\/j.medcli.2013.10.007","article-title":"Plasmapheresis in the treatment of an acute pancreatitis due to hypertriglyceridemia","volume":"142","author":"Zborovszky","year":"2014","journal-title":"Med Clin (Barc)"},{"issue":"7","key":"10.1016\/j.ajem.2018.01.092_bb0140","doi-asserted-by":"crossref","first-page":"978","DOI":"10.1016\/j.ajem.2017.02.006","article-title":"Serum calcium as an indicator of persistent organ failure in acute pancreatitis","volume":"35","author":"Peng","year":"2017","journal-title":"Am J Emerg Med"}],"container-title":["The American Journal of Emergency Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0735675718301062?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0735675718301062?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T15:39:26Z","timestamp":1760024366000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0735675718301062"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,10]]},"references-count":28,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2018,10]]}},"alternative-id":["S0735675718301062"],"URL":"https:\/\/doi.org\/10.1016\/j.ajem.2018.01.092","relation":{},"ISSN":["0735-6757"],"issn-type":[{"value":"0735-6757","type":"print"}],"subject":[],"published":{"date-parts":[[2018,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Penta-therapy for severe acute hyperlipidemic pancreatitis","name":"articletitle","label":"Article Title"},{"value":"The American Journal of Emergency Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajem.2018.01.092","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}