{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T16:30:18Z","timestamp":1786984218451,"version":"build-2736575974"},"reference-count":22,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2020,7,1]],"date-time":"2020-07-01T00:00:00Z","timestamp":1593561600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,7,1]],"date-time":"2020-07-01T00:00:00Z","timestamp":1593561600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100011542","name":"CCaTS Small grant program, CTSA","doi-asserted-by":"publisher","award":["UL1 TR000135"],"award-info":[{"award-number":["UL1 TR000135"]}],"id":[{"id":"10.13039\/100011542","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006108","name":"National Center for Advancing Translational Sciences","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006108","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The American Journal of Emergency Medicine"],"published-print":{"date-parts":[[2020,7]]},"DOI":"10.1016\/j.ajem.2019.09.007","type":"journal-article","created":{"date-parts":[[2019,11,25]],"date-time":"2019-11-25T11:31:15Z","timestamp":1574681475000},"page":"1310-1314","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":39,"title":["Effectiveness and safety of droperidol in a United States emergency department"],"prefix":"10.1016","volume":"38","author":[{"given":"Charlene M.","family":"Gaw","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Cabrera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernanda","family":"Bellolio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alicia E.","family":"Mattson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine M.","family":"Lohse","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Molly M.","family":"Jeffery","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.ajem.2019.09.007_b0005","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1016\/S0736-4679(03)00044-1","article-title":"Droperidol in the emergency department: is it safe?","volume":"24","author":"Richards","year":"2003","journal-title":"J Emerg Med"},{"key":"10.1016\/j.ajem.2019.09.007_b0010","unstructured":"Administration, U.S.F.a.D., Inapsine (droperidol) Dear Healthcare Professional Letter Dec 2001. Safety Alerts for Human Medical Products, 2001."},{"issue":"4","key":"10.1016\/j.ajem.2019.09.007_b0015","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1067\/mem.2003.110","article-title":"Droperidol, QT prolongation, and sudden death: what is the evidence?","volume":"41","author":"Kao","year":"2003","journal-title":"Ann Emerg Med"},{"issue":"1","key":"10.1016\/j.ajem.2019.09.007_b0020","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1097\/00000542-200207000-00061","article-title":"The FDA droperidol warning: is it justified?","volume":"97","author":"Bailey","year":"2002","journal-title":"Anesthesiology"},{"issue":"11","key":"10.1016\/j.ajem.2019.09.007_b0025","doi-asserted-by":"crossref","first-page":"1174","DOI":"10.2146\/ajhp060505","article-title":"Evidence-based review of the black-box warning for droperidol","volume":"64","author":"Jackson","year":"2007","journal-title":"Am J Health Syst Pharm"},{"issue":"5","key":"10.1016\/j.ajem.2019.09.007_b0030","doi-asserted-by":"crossref","first-page":"1377","DOI":"10.1213\/01.ANE.0000063923.87560.37","article-title":"Food and drug administration black box warning on the perioperative use of droperidol: a review of the cases","volume":"96","author":"Habib","year":"2003","journal-title":"Anesth Analg"},{"issue":"5","key":"10.1016\/j.ajem.2019.09.007_b0035","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1016\/j.jclinane.2007.02.008","article-title":"Changing patterns of postoperative nausea and vomiting prophylaxis drug use in an academic anesthesia practice","volume":"19","author":"Wax","year":"2007","journal-title":"J Clin Anesth"},{"issue":"1","key":"10.1016\/j.ajem.2019.09.007_b0040","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.jclinane.2007.08.003","article-title":"The use of droperidol before and after the Food and Drug Administration black box warning: a survey of the members of the Society of Ambulatory Anesthesia","volume":"20","author":"Habib","year":"2008","journal-title":"J Clin Anesth"},{"issue":"1","key":"10.1016\/j.ajem.2019.09.007_b0045","first-page":"3","article-title":"The effects of the FDA warning on the use of droperidol by u.s. Emergency physicians","volume":"4","author":"Richards","year":"2003","journal-title":"Cal J Emerg Med"},{"issue":"2","key":"10.1016\/j.ajem.2019.09.007_b0050","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1097\/ALN.0b013e31827dde8d","article-title":"Does low-dose droperidol increase the risk of polymorphic ventricular tachycardia or death in the surgical patient?","volume":"118","author":"Nuttall","year":"2013","journal-title":"Anesthesiology"},{"issue":"1","key":"10.1016\/j.ajem.2019.09.007_b0055","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.jemermed.2014.12.024","article-title":"American academy of emergency medicine position statement: safety of droperidol use in the emergency department","volume":"49","author":"Perkins","year":"2015","journal-title":"J Emerg Med"},{"issue":"2","key":"10.1016\/j.ajem.2019.09.007_b0060","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1177\/1060028014554445","article-title":"Droperidol for the treatment of acute migraine headaches","volume":"49","author":"Thomas","year":"2015","journal-title":"Ann Pharmacother"},{"issue":"3","key":"10.1016\/j.ajem.2019.09.007_b0065","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1016\/j.annemergmed.2016.09.021","article-title":"Droperidol or olanzapine, intramuscularly or intravenously, monotherapy or combination therapy for sedating acute behavioral disturbance","volume":"69","author":"Isbister","year":"2017","journal-title":"Ann Emerg Med"},{"issue":"3","key":"10.1016\/j.ajem.2019.09.007_b0070","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1016\/j.annemergmed.2016.07.033","article-title":"Midazolam-droperidol, droperidol, or olanzapine for acute agitation: a randomized clinical trial","volume":"69","author":"Taylor","year":"2017","journal-title":"Ann Emerg Med"},{"issue":"3","key":"10.1016\/j.ajem.2019.09.007_b0075","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1016\/j.annemergmed.2015.03.016","article-title":"The safety and effectiveness of droperidol for sedation of acute behavioral disturbance in the emergency department","volume":"66","author":"Calver","year":"2015","journal-title":"Ann Emerg Med"},{"issue":"6","key":"10.1016\/j.ajem.2019.09.007_b0080","doi-asserted-by":"crossref","first-page":"970","DOI":"10.1016\/j.ajem.2013.03.026","article-title":"Parenteral sedation of elderly patients with acute behavioral disturbance in the ED","volume":"31","author":"Calver","year":"2013","journal-title":"Am J Emerg Med"},{"key":"10.1016\/j.ajem.2019.09.007_b0085","first-page":"S162","article-title":"Is droperidol safe and effective in older adults?","author":"Gaw","year":"2019","journal-title":"J Am Geriatr Soc"},{"issue":"10","key":"10.1016\/j.ajem.2019.09.007_b0090","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pmed.0040296","article-title":"The strengthening the reporting of observational studies in epidemiology (STROBE) statement: guidelines for reporting observational studies","volume":"4","author":"von Elm","year":"2007","journal-title":"PLoS Med"},{"issue":"5","key":"10.1016\/j.ajem.2019.09.007_b0095","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1016\/j.annemergmed.2014.03.017","article-title":"Antiemetic use for nausea and vomiting in adult emergency department patients: randomized controlled trial comparing ondansetron, metoclopramide, and placebo","volume":"64","author":"Egerton-Warburton","year":"2014","journal-title":"Ann Emerg Med"},{"issue":"6","key":"10.1016\/j.ajem.2019.09.007_b0100","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1080\/10903127.2018.1445329","article-title":"A prospective before and after study of droperidol for prehospital acute behavioral disturbance","volume":"22","author":"Page","year":"2018","journal-title":"Prehosp Emerg Care"},{"issue":"4","key":"10.1016\/j.ajem.2019.09.007_b0105","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1111\/bcp.12527","article-title":"Small doses of droperidol do not present relevant torsadogenic actions: a double-blind, ondansetron-controlled study","volume":"79","author":"Tracz","year":"2015","journal-title":"Br J Clin Pharmacol"},{"key":"10.1016\/j.ajem.2019.09.007_b0110","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1146\/annurev-publhealth-031914-122957","article-title":"The prescription opioid and heroin crisis: a public health approach to an epidemic of addiction","volume":"36","author":"Kolodny","year":"2015","journal-title":"Annu Rev Public Health"}],"container-title":["The American Journal of Emergency Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0735675719306126?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0735675719306126?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T15:46:51Z","timestamp":1760024811000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0735675719306126"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,7]]},"references-count":22,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2020,7]]}},"alternative-id":["S0735675719306126"],"URL":"https:\/\/doi.org\/10.1016\/j.ajem.2019.09.007","relation":{},"ISSN":["0735-6757"],"issn-type":[{"value":"0735-6757","type":"print"}],"subject":[],"published":{"date-parts":[[2020,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effectiveness and safety of droperidol in a United States emergency department","name":"articletitle","label":"Article Title"},{"value":"The American Journal of Emergency Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajem.2019.09.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}