{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T00:47:26Z","timestamp":1760057246330,"version":"build-2065373602"},"reference-count":18,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,4,1]],"date-time":"2021-04-01T00:00:00Z","timestamp":1617235200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,4,1]],"date-time":"2021-04-01T00:00:00Z","timestamp":1617235200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The American Journal of Emergency Medicine"],"published-print":{"date-parts":[[2021,4]]},"DOI":"10.1016\/j.ajem.2020.09.031","type":"journal-article","created":{"date-parts":[[2020,9,19]],"date-time":"2020-09-19T20:37:02Z","timestamp":1600547822000},"page":"264.e1-264.e3","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Failure of painful eye movements to respond to topical anesthetics supports the diagnosis of optic neuritis"],"prefix":"10.1016","volume":"42","author":[{"given":"Dietrich","family":"Jehle","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mary Claire","family":"Lark","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Clay","family":"O'Brien","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ajem.2020.09.031_bb0005","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1080\/08820530390895172","article-title":"Optic neuritis in adults and children","volume":"18","author":"Boomer","year":"2003","journal-title":"Semin Ophthalmol"},{"issue":"37","key":"10.1016\/j.ajem.2020.09.031_bb0010","first-page":"616","article-title":"The diagnosis and treatment of optic neuritis","volume":"112","author":"Wilhelm","year":"2015","journal-title":"Dtsch Arztebl Int"},{"key":"10.1016\/j.ajem.2020.09.031_bb0015","series-title":"Neuro-ophthalmology: diagnosis and management","article-title":"Visual loss: optic neuropathies","author":"Liu","year":"2001"},{"issue":"7","key":"10.1016\/j.ajem.2020.09.031_bb0020","doi-asserted-by":"crossref","first-page":"1349","DOI":"10.1007\/s00415-014-7349-0","article-title":"The incidence of clinically isolated syndrome in a multi-ethnic cohort","volume":"261","author":"Langer-Gould","year":"2014","journal-title":"J Neurol"},{"issue":"9","key":"10.1016\/j.ajem.2020.09.031_bb0025","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1056\/NEJM199202273260901","article-title":"A randomized, controlled trial of corticosteroids in the treatment of acute optic neuritis","volume":"326","author":"Beck","year":"1992","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ajem.2020.09.031_bb0030","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/S1474-4422(05)00992-0","article-title":"The neuro-ophthalmology of multiple sclerosis","volume":"4","author":"Frohman","year":"2005","journal-title":"Lancet Neurol"},{"issue":"5","key":"10.1016\/j.ajem.2020.09.031_bb0035","doi-asserted-by":"crossref","first-page":"1236","DOI":"10.1212\/CON.0000000000000768","article-title":"Optic neuritis","volume":"25","author":"Bennett","year":"2019","journal-title":"Continuum (Minneap Minn)"},{"issue":"6","key":"10.1016\/j.ajem.2020.09.031_bb0040","first-page":"727","article-title":"Multiple sclerosis risk after optic neuritis: final optic neuritis treatment trial follow-up","volume":"65","author":"Optic Neuritis Study Group","year":"2008","journal-title":"Arch Neurol"},{"key":"10.1016\/j.ajem.2020.09.031_bb0045","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1038\/eye.2011.81","article-title":"Optic neuritis","volume":"25","author":"Pau","year":"2011","journal-title":"Eye"},{"key":"10.1016\/j.ajem.2020.09.031_bb0050","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1097\/00055735-200212000-00006","article-title":"Acute demyelinating optic neuritis","volume":"13","author":"Foroozan","year":"2002","journal-title":"Curr Opin Ophthalmol"},{"key":"10.1016\/j.ajem.2020.09.031_bb0055","doi-asserted-by":"crossref","first-page":"1673","DOI":"10.1001\/archopht.1991.01080120057025","volume":"109","year":"1991","journal-title":"Arch Ophthalmol"},{"key":"10.1016\/j.ajem.2020.09.031_bb0060","doi-asserted-by":"crossref","first-page":"1273","DOI":"10.1056\/NEJMcp053247","article-title":"Clinical practice. Optic neuritis","volume":"354","author":"Balcer","year":"2006","journal-title":"N Engl J Med"},{"issue":"6","key":"10.1016\/j.ajem.2020.09.031_bb0065","article-title":"Visual function 15 years after optic neuritis: a final follow-up report from the optic neuritis treatment trial","volume":"115","year":"2008","journal-title":"Ophthalmology"},{"key":"10.1016\/j.ajem.2020.09.031_bb0070","first-page":"1","article-title":"Retrobulbar neuritis","author":"Publishing","year":"2020","journal-title":"Harvard Health"},{"key":"10.1016\/j.ajem.2020.09.031_bb0075","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1136\/bjo.2005.085399","article-title":"Clinical profile of simultaneous bilateral optic neuritis in adults","volume":"90","author":"de la Cruz","year":"2006","journal-title":"Br J Ophthalmol"},{"issue":"2","key":"10.1016\/j.ajem.2020.09.031_bb0080","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1097\/WNO.0b013e31825662f1","article-title":"Neuromyelitis optica","volume":"32","author":"Morrow","year":"2012","journal-title":"J Neuroophthalmol"},{"key":"10.1016\/j.ajem.2020.09.031_bb0085","first-page":"8740264","article-title":"Unilateral optic neuritis: a rare complication after measles-mumps-rubella vaccination in a 30-year-old woman","volume":"2016","author":"De Giacinto","year":"2016","journal-title":"Case Rep Ophthalmol Med"},{"issue":"2","key":"10.1016\/j.ajem.2020.09.031_bb0090","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1002\/ana.410120202","article-title":"Neurological complications of immunization","volume":"12","author":"Fenichel","year":"1982","journal-title":"Ann Neurol"}],"container-title":["The American Journal of Emergency Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0735675720308251?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0735675720308251?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T15:53:22Z","timestamp":1760025202000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0735675720308251"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,4]]},"references-count":18,"alternative-id":["S0735675720308251"],"URL":"https:\/\/doi.org\/10.1016\/j.ajem.2020.09.031","relation":{},"ISSN":["0735-6757"],"issn-type":[{"type":"print","value":"0735-6757"}],"subject":[],"published":{"date-parts":[[2021,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Failure of painful eye movements to respond to topical anesthetics supports the diagnosis of optic neuritis","name":"articletitle","label":"Article Title"},{"value":"The American Journal of Emergency Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajem.2020.09.031","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}