{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,24]],"date-time":"2026-01-24T18:20:19Z","timestamp":1769278819000,"version":"3.49.0"},"reference-count":13,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,8,1]],"date-time":"2021-08-01T00:00:00Z","timestamp":1627776000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,8,1]],"date-time":"2021-08-01T00:00:00Z","timestamp":1627776000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The American Journal of Emergency Medicine"],"published-print":{"date-parts":[[2021,8]]},"DOI":"10.1016\/j.ajem.2020.10.046","type":"journal-article","created":{"date-parts":[[2020,10,27]],"date-time":"2020-10-27T22:21:28Z","timestamp":1603837288000},"page":"430-436","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"special_numbering":"C","title":["Hollow adrenal gland sign on dual-phase contrast-enhanced CT in critically ill patients with sepsis"],"prefix":"10.1016","volume":"46","author":[{"given":"Jong Eun","family":"Park","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gun Tak","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiyeong","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Young-Min","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tae Gun","family":"Shin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Se Uk","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Taerim","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hee","family":"Yoon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Won Chul","family":"Cha","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sung Yeon","family":"Hwang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ajem.2020.10.046_bb0005","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1001\/jama.2016.0287","article-title":"The third international consensus definitions for Sepsis and septic shock (Sepsis-3)","volume":"315","author":"Singer","year":"2016","journal-title":"JAMA"},{"key":"10.1016\/j.ajem.2020.10.046_bb0010","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1016\/S0140-6736(19)32989-7","article-title":"Global, regional, and national sepsis incidence and mortality, 1990-2017: analysis for the global burden of disease study","volume":"395","author":"Rudd","year":"2020","journal-title":"Lancet"},{"key":"10.1016\/j.ajem.2020.10.046_bb0015","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1186\/s13054-019-2478-6","article-title":"Frequency and mortality of septic shock in Europe and North America: a systematic review and meta-analysis","volume":"23","author":"Vincent","year":"2019","journal-title":"Crit Care"},{"key":"10.1016\/j.ajem.2020.10.046_bb0020","doi-asserted-by":"crossref","first-page":"552","DOI":"10.3109\/02841859909175583","article-title":"Impact of CT in patients with sepsis of unknown origin","volume":"40","author":"Barkhausen","year":"1999","journal-title":"Acta Radiol"},{"key":"10.1016\/j.ajem.2020.10.046_bb0025","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1097\/ALN.0b013e318225cfd7","article-title":"The absence of adrenal gland enlargement during septic shock predicts mortality: a computed tomography study of 239 patients","volume":"115","author":"Jung","year":"2011","journal-title":"Anesthesiology"},{"key":"10.1016\/j.ajem.2020.10.046_bb0030","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1186\/s40560-016-0205-9","article-title":"Decreasing skeletal muscle as a risk factor for mortality in elderly patients with sepsis: a retrospective cohort study","volume":"5","author":"Shibahashi","year":"2017","journal-title":"J Intensive Care"},{"key":"10.1016\/j.ajem.2020.10.046_bb0035","doi-asserted-by":"crossref","first-page":"5378","DOI":"10.1007\/s00330-019-06172-1","article-title":"The hollow adrenal gland sign: a newly described enhancing pattern of the adrenal gland on dual-phase contrast-enhanced CT for predicting the prognosis of patients with septic shock","volume":"29","author":"Peng","year":"2019","journal-title":"Eur Radiol"},{"key":"10.1016\/j.ajem.2020.10.046_bb0040","doi-asserted-by":"crossref","first-page":"146","DOI":"10.15441\/ceem.17.204","article-title":"Korean shock society septic shock registry: a preliminary report","volume":"4","author":"Shin","year":"2017","journal-title":"Clin Exp Emerg Med"},{"key":"10.1016\/j.ajem.2020.10.046_bb0045","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1016\/j.chest.2017.12.021","article-title":"Management of Refractory Vasodilatory Shock","volume":"154","author":"Jentzer","year":"2018","journal-title":"Chest"},{"key":"10.1016\/j.ajem.2020.10.046_bb0050","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1056\/NEJMoa1705716","article-title":"Hydrocortisone plus fludrocortisone for adults with septic shock","volume":"378","author":"Annane","year":"2018","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ajem.2020.10.046_bb0055","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1097\/RCT.0b013e3181d53276","article-title":"Adrenal glands in hypovolemic shock: preservation of contrast enhancement at dynamic computed tomography","volume":"34","author":"Ito","year":"2010","journal-title":"J Comput Assist Tomogr"},{"key":"10.1016\/j.ajem.2020.10.046_bb0060","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1007\/s11604-014-0354-5","article-title":"Traumatic hypovolemic shock revisited: the spectrum of contrast-enhanced abdominal computed tomography findings and clinical implications for its management","volume":"32","author":"Higashi","year":"2014","journal-title":"Jpn J Radiol"},{"key":"10.1016\/j.ajem.2020.10.046_bb0065","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.carj.2016.07.006","article-title":"Contrast-enhanced computed tomography in intensive care unit patients with acute clinical deterioration: impact of Hyperattenuating adrenal glands","volume":"68","author":"Boos","year":"2017","journal-title":"Can Assoc Radiol J"}],"container-title":["The American Journal of Emergency Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0735675720309426?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0735675720309426?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T15:59:49Z","timestamp":1760025589000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0735675720309426"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,8]]},"references-count":13,"alternative-id":["S0735675720309426"],"URL":"https:\/\/doi.org\/10.1016\/j.ajem.2020.10.046","relation":{},"ISSN":["0735-6757"],"issn-type":[{"value":"0735-6757","type":"print"}],"subject":[],"published":{"date-parts":[[2021,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Hollow adrenal gland sign on dual-phase contrast-enhanced CT in critically ill patients with sepsis","name":"articletitle","label":"Article Title"},{"value":"The American Journal of Emergency Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajem.2020.10.046","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}