{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T19:40:29Z","timestamp":1761766829206,"version":"build-2065373602"},"reference-count":25,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T00:00:00Z","timestamp":1614556800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T00:00:00Z","timestamp":1614556800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The American Journal of Emergency Medicine"],"published-print":{"date-parts":[[2021,3]]},"DOI":"10.1016\/j.ajem.2020.12.066","type":"journal-article","created":{"date-parts":[[2020,12,28]],"date-time":"2020-12-28T12:08:54Z","timestamp":1609157334000},"page":"84-89","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"special_numbering":"C","title":["Is \u201cpain before vomiting\u201d useful?: Diagnostic performance of the classic patient history item in acute appendicitis"],"prefix":"10.1016","volume":"41","author":[{"given":"Toshihiko","family":"Takada","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryota","family":"Inokuchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hongja","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sho","family":"Sasaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuhiko","family":"Terada","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hajime","family":"Yokota","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shinya","family":"Hattori","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wakako","family":"Mikami","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tadao","family":"Kubota","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shunichi","family":"Fukuhara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"19","key":"10.1016\/j.ajem.2020.12.066_bb0005","doi-asserted-by":"crossref","first-page":"1589","DOI":"10.1001\/jama.1996.03540190061030","article-title":"Does this patient have appendicitis?","volume":"276","author":"Wagner","year":"1996","journal-title":"JAMA"},{"issue":"2","key":"10.1016\/j.ajem.2020.12.066_bb0010","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1148\/radiology.215.2.r00ma24337","article-title":"Appendicitis at the millennium","volume":"215","author":"Birnbaum","year":"2000","journal-title":"Radiology"},{"issue":"11","key":"10.1016\/j.ajem.2020.12.066_bb0015","doi-asserted-by":"crossref","first-page":"1244","DOI":"10.1111\/j.1553-2712.2000.tb00470.x","article-title":"False-negative and false-positive errors in abdominal pain evaluation: failure to diagnose acute appendicitis and unnecessary surgery","volume":"7","author":"Graff","year":"2000","journal-title":"Acad Emerg Med"},{"issue":"1","key":"10.1016\/j.ajem.2020.12.066_bb0020","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1177\/000313481307900138","article-title":"Accuracies of diagnostic methods for acute appendicitis","volume":"79","author":"Park","year":"2013","journal-title":"Am Surg"},{"issue":"6","key":"10.1016\/j.ajem.2020.12.066_bb0025","first-page":"828","article-title":"Diagnosis of appendicitis: part 1. History and physical examination","volume":"77","author":"Ebell","year":"2008","journal-title":"Am Fam Physician"},{"issue":"3","key":"10.1016\/j.ajem.2020.12.066_bb0030","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/j.ijsu.2012.02.006","article-title":"Diagnosis of acute appendicitis","volume":"10","author":"Petroianu","year":"2012","journal-title":"Int J Surg"},{"issue":"3","key":"10.1016\/j.ajem.2020.12.066_bb0035","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1056\/NEJMcp013351","article-title":"Clinical practice. Suspected appendicitis","volume":"348","author":"Paulson","year":"2003","journal-title":"N Engl J Med"},{"year":"2010","series-title":"Cope\u2019s early diagnosis of the acute abdomen","author":"Silen","key":"10.1016\/j.ajem.2020.12.066_bb0040"},{"issue":"2","key":"10.1016\/j.ajem.2020.12.066_bb0045","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/0002-9610(76)90101-X","article-title":"Abdominal pain. An analysis of 1000 consecutive cases in a University Hospital emergency room","volume":"131","author":"Brewer","year":"1976","journal-title":"Am J Surg"},{"issue":"1","key":"10.1016\/j.ajem.2020.12.066_bb0050","doi-asserted-by":"crossref","first-page":"W1","DOI":"10.7326\/0003-4819-138-1-200301070-00012-w1","article-title":"The STARD statement for reporting studies of diagnostic accuracy: explanation and elaboration","volume":"138","author":"Bossuyt","year":"2003","journal-title":"Ann Intern Med"},{"issue":"5","key":"10.1016\/j.ajem.2020.12.066_bb0055","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1016\/S0196-0644(86)80993-3","article-title":"A practical score for the early diagnosis of acute appendicitis","volume":"15","author":"Alvarado","year":"1986","journal-title":"Ann Emerg Med"},{"issue":"4","key":"10.1016\/j.ajem.2020.12.066_bb0060","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1016\/j.annemergmed.2014.02.025","article-title":"What are the most clinically useful cutoffs for the Alvarado and pediatric appendicitis scores? A systematic review","volume":"64","author":"Ebell","year":"2014","journal-title":"Ann Emerg Med"},{"issue":"7","key":"10.1016\/j.ajem.2020.12.066_bb0065","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1016\/j.jclinepi.2009.12.008","article-title":"Missing covariate data in medical research: to impute is better than to ignore","volume":"63","author":"Janssen","year":"2010","journal-title":"J Clin Epidemiol"},{"issue":"10","key":"10.1016\/j.ajem.2020.12.066_bb0070","doi-asserted-by":"crossref","first-page":"1092","DOI":"10.1016\/j.jclinepi.2006.01.009","article-title":"Using the outcome for imputation of missing predictor values was preferred","volume":"59","author":"Moons","year":"2006","journal-title":"J Clin Epidemiol"},{"year":"2012","series-title":"Flexible imputation of missing data","author":"Van Buuren","key":"10.1016\/j.ajem.2020.12.066_bb0075"},{"issue":"8476","key":"10.1016\/j.ajem.2020.12.066_bb0080","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/S0140-6736(86)90837-8","article-title":"Statistical methods for assessing agreement between two methods of clinical measurement","volume":"1","author":"Bland","year":"1986","journal-title":"Lancet"},{"issue":"11","key":"10.1016\/j.ajem.2020.12.066_bb0085","doi-asserted-by":"crossref","first-page":"1129","DOI":"10.1016\/S0895-4356(03)00177-X","article-title":"The diagnostic odds ratio: a single indicator of test performance","volume":"56","author":"Glas","year":"2003","journal-title":"J Clin Epidemiol"},{"key":"10.1016\/j.ajem.2020.12.066_bb0090","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1080\/01621459.1927.10502953","article-title":"Probable inference, the law of succession, and statistical inference","volume":"22","author":"Wilson","year":"1927","journal-title":"J Am Stat Assoc"},{"author":"Team","key":"10.1016\/j.ajem.2020.12.066_bb0095"},{"issue":"2","key":"10.1016\/j.ajem.2020.12.066_bb0100","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1148\/radiol.2282011860","article-title":"Measurement of observer agreement","volume":"228","author":"Kundel","year":"2003","journal-title":"Radiology"},{"issue":"4","key":"10.1016\/j.ajem.2020.12.066_bb0105","doi-asserted-by":"crossref","first-page":"995","DOI":"10.1016\/j.idc.2010.07.012","article-title":"Infectious causes of appendicitis","volume":"24","author":"Lamps","year":"2010","journal-title":"Infect Dis Clin North Am"},{"issue":"2","key":"10.1016\/j.ajem.2020.12.066_bb0110","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1111\/j.1365-2362.2011.02562.x","article-title":"Assessing the incremental value of diagnostic and prognostic markers: a review and illustration","volume":"42","author":"Steyerberg","year":"2012","journal-title":"Eur J Clin Invest"},{"issue":"1","key":"10.1016\/j.ajem.2020.12.066_bb0115","doi-asserted-by":"crossref","first-page":"W1","DOI":"10.7326\/M14-0698","article-title":"Transparent reporting of a multivariable prediction model for individual prognosis or diagnosis (TRIPOD): explanation and elaboration","volume":"162","author":"Moons","year":"2015","journal-title":"Ann Intern Med"},{"issue":"7","key":"10.1016\/j.ajem.2020.12.066_bb0120","doi-asserted-by":"crossref","first-page":"537","DOI":"10.7326\/0003-4819-141-7-200410050-00011","article-title":"Systematic review: computed tomography and ultrasonography to detect acute appendicitis in adults and adolescents","volume":"141","author":"Terasawa","year":"2004","journal-title":"Ann Intern Med"},{"issue":"9","key":"10.1016\/j.ajem.2020.12.066_bb0125","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0136996","article-title":"The role of digital rectal examination for diagnosis of acute appendicitis: a systematic review and meta-analysis","volume":"10","author":"Takada","year":"2015","journal-title":"PLoS One"}],"container-title":["The American Journal of Emergency Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0735675720311864?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0735675720311864?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T15:50:33Z","timestamp":1760025033000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0735675720311864"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,3]]},"references-count":25,"alternative-id":["S0735675720311864"],"URL":"https:\/\/doi.org\/10.1016\/j.ajem.2020.12.066","relation":{},"ISSN":["0735-6757"],"issn-type":[{"type":"print","value":"0735-6757"}],"subject":[],"published":{"date-parts":[[2021,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Is \u201cpain before vomiting\u201d useful?: Diagnostic performance of the classic patient history item in acute appendicitis","name":"articletitle","label":"Article Title"},{"value":"The American Journal of Emergency Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajem.2020.12.066","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}