{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T03:20:24Z","timestamp":1783394424103,"version":"3.54.6"},"reference-count":17,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The American Journal of Emergency Medicine"],"published-print":{"date-parts":[[2021,9]]},"DOI":"10.1016\/j.ajem.2021.03.074","type":"journal-article","created":{"date-parts":[[2021,3,28]],"date-time":"2021-03-28T17:26:46Z","timestamp":1616952406000},"page":"149-153","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"special_numbering":"C","title":["Characterization of ketamine usage in a large tertiary-care emergency department"],"prefix":"10.1016","volume":"47","author":[{"given":"Kelly","family":"McKinley","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patricia","family":"Panakos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Yousef","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ajem.2021.03.074_bb0005","doi-asserted-by":"crossref","DOI":"10.1016\/j.tacc.2014.03.002","article-title":"Ketamine- more mechanisms of action than just NMDA blockade","volume":"4","author":"Sleigh","year":"2014","journal-title":"Trends Anaesthesia Crit Care"},{"key":"10.1016\/j.ajem.2021.03.074_bb0010","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1038\/aps.2016.5","article-title":"Ketamine use in current clinical practice","volume":"37","author":"Gao","year":"2016","journal-title":"Acta Pharmacol Sin"},{"issue":"5","key":"10.1016\/j.ajem.2021.03.074_bb0015","first-page":"731","article-title":"Consensus guidelines on the use of intravenous ketamine infusions for acute pain management from the American Society of Regional Anesthesia and Pain Medicine statement prepared for the American academy of emergency medicine","volume":"54","author":"Schwenk","year":"2018","journal-title":"J Emerg Med"},{"issue":"6","key":"10.1016\/j.ajem.2021.03.074_bb0020","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1097\/CCM.0000000000004335","article-title":"The reemergence of ketamine for treatment in critically ill adults","volume":"48","author":"Hurth","year":"2020","journal-title":"Crit Care Med"},{"issue":"5","key":"10.1016\/j.ajem.2021.03.074_bb0025","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1016\/j.annemergmed.2010.11.030","article-title":"Clinical practice guideline for emergency department ketamine dissociative sedation: 2011 update","volume":"57","author":"Green","year":"2011","journal-title":"Ann Emerg Med"},{"key":"10.1016\/j.ajem.2021.03.074_bb0030","article-title":"Efficacy of ketamine for initial control of acute agitation in the emergency department: a randomized study","author":"Lin","year":"2020","journal-title":"Am J Emerg Med"},{"issue":"1","key":"10.1016\/j.ajem.2021.03.074_bb0035","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/j.jemermed.2019.09.019","article-title":"Evaluation of ketamine for excited delirium syndrome in the adult emeregency department","volume":"58","author":"Li","year":"2020","journal-title":"J Emerg Med"},{"issue":"6","key":"10.1016\/j.ajem.2021.03.074_bb0040","doi-asserted-by":"crossref","first-page":"712","DOI":"10.1016\/j.jemermed.2015.02.019","article-title":"Ketamine use for acute agitation in the emergency department","volume":"48","author":"Hopper","year":"2015","journal-title":"J Emerg Med"},{"issue":"5","key":"10.1016\/j.ajem.2021.03.074_bb0045","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1016\/j.annemergmed.2015.11.028","article-title":"Ketamine as rescue treatment for difficult-to-sedate severe acute behavioral disturbance in the emergency department","volume":"67","author":"Isbister","year":"2016","journal-title":"Ann Emerg Med"},{"issue":"7","key":"10.1016\/j.ajem.2021.03.074_bb0050","doi-asserted-by":"crossref","first-page":"1000","DOI":"10.1016\/j.ajem.2017.02.026","article-title":"Ketamine as a first-line treatment for severely agitated emergency department patients","volume":"35","author":"Riddell","year":"2017","journal-title":"Am J Emerg Med"},{"issue":"3","key":"10.1016\/j.ajem.2021.03.074_bb0055","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1016\/j.ajem.2017.12.014","article-title":"In reply: ketamine is an important therapy for prehospital agitation \u2013 its exact role and side effect profile are still undefined","volume":"36","author":"Cole","year":"2018","journal-title":"Am J Emerg Med"},{"key":"10.1016\/j.ajem.2021.03.074_bb0060","series-title":"Ketamine [package insert]","year":"2020"},{"key":"10.1016\/j.ajem.2021.03.074_bb0065","doi-asserted-by":"crossref","first-page":"2248","DOI":"10.2146\/ajhp110136","article-title":"Combination of ketamine and propofol versus either agent alone for procedural sedation in the emergency department","volume":"68","author":"Thomas","year":"2011","journal-title":"Am J Health-Syst Pharm"},{"key":"10.1016\/j.ajem.2021.03.074_bb0070","doi-asserted-by":"crossref","first-page":"1320","DOI":"10.2146\/ajhp100437","article-title":"Rapid-sequence intubation and the role of the emergency department pharmacist","volume":"68","author":"Hampton","year":"2011","journal-title":"Am J Health-Syst Pharm"},{"issue":"4","key":"10.1016\/j.ajem.2021.03.074_bb0075","doi-asserted-by":"crossref","first-page":"349","DOI":"10.4037\/NCI.0b013e31826e18d1","article-title":"Pharmacology of procedural sedation","volume":"23","author":"Adams","year":"2012","journal-title":"AACH Adv Critl Care"},{"key":"10.1016\/j.ajem.2021.03.074_bb0080","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.annemergmed.2006.08.002","article-title":"A prospective evaluation of \u201cketofol\u201d (ketamine\/propofol) combination for procedural sedation and analgesia in the emergency department","volume":"49","author":"Willman","year":"2007","journal-title":"Ann Emerg Med"},{"issue":"2","key":"10.1016\/j.ajem.2021.03.074_bb0085","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1016\/j.annemergmed.2008.12.011","article-title":"Predictors of airway and respiratory adverse events with ketamine sedation in the emergency department: an individual-patient data meta-analysis of 8,282 children","volume":"54","author":"Green","year":"2009","journal-title":"Ann Emerg Med"}],"container-title":["The American Journal of Emergency Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0735675721002618?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0735675721002618?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T15:53:47Z","timestamp":1760025227000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0735675721002618"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,9]]},"references-count":17,"alternative-id":["S0735675721002618"],"URL":"https:\/\/doi.org\/10.1016\/j.ajem.2021.03.074","relation":{},"ISSN":["0735-6757"],"issn-type":[{"value":"0735-6757","type":"print"}],"subject":[],"published":{"date-parts":[[2021,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Characterization of ketamine usage in a large tertiary-care emergency department","name":"articletitle","label":"Article Title"},{"value":"The American Journal of Emergency Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajem.2021.03.074","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}