{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,25]],"date-time":"2026-02-25T05:32:47Z","timestamp":1771997567959,"version":"3.50.1"},"reference-count":11,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The American Journal of Emergency Medicine"],"published-print":{"date-parts":[[2021,10]]},"DOI":"10.1016\/j.ajem.2021.04.018","type":"journal-article","created":{"date-parts":[[2021,4,15]],"date-time":"2021-04-15T01:51:16Z","timestamp":1618451476000},"page":"83-86","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"special_numbering":"C","title":["Markers for invasive bacterial infections in previously healthy children"],"prefix":"10.1016","volume":"48","author":[{"given":"Iker","family":"Gangoiti","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Catarina-Livana","family":"Fernandez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mikel","family":"Gallego","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Borja","family":"Gomez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Javier","family":"Benito","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Santiago","family":"Mintegi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ajem.2021.04.018_bb0005","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1016\/j.annemergmed.2014.10.022","article-title":"Repeated emergency department visits among children admitted with meningitis or septicemia: a population-based study","volume":"65","author":"Vaillancourt","year":"2015","journal-title":"Ann Emerg Med"},{"key":"10.1016\/j.ajem.2021.04.018_bb0010","doi-asserted-by":"crossref","first-page":"1094","DOI":"10.1136\/bmj.327.7423.1094","article-title":"Unexplained fever in young children: how to manage severe bacterial infection","volume":"327","author":"Brook","year":"2003","journal-title":"BMJ"},{"key":"10.1016\/j.ajem.2021.04.018_bb0015","doi-asserted-by":"crossref","first-page":"d3082","DOI":"10.1136\/bmj.d3082","article-title":"Diagnostic value of laboratory tests in identifying serious infections in febrile children: systematic review","volume":"342","author":"Van den Bruel","year":"2011","journal-title":"BMJ"},{"issue":"4","key":"10.1016\/j.ajem.2021.04.018_bb0020","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1097\/MEJ.0000000000000453","article-title":"Characteristics of children with microbiologically confirmed invasive bacterial infections in the emergency department","volume":"25","author":"Gangoiti","year":"2018","journal-title":"Eur J Emerg Med"},{"issue":"1","key":"10.1016\/j.ajem.2021.04.018_bb0025","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1097\/01.PCC.0000149131.72248.E6","article-title":"International pediatric sepsis consensus conference: definitions for sepsis and organ dysfunction in pediatrics","volume":"6","author":"Goldstein","year":"2005","journal-title":"Pediatr Crit Care Med"},{"key":"10.1016\/j.ajem.2021.04.018_bb0030","series-title":"Advanced pediatric life support: the pediatric emergency medicine resource","author":"Gausche-Hill","year":"2003"},{"key":"10.1016\/j.ajem.2021.04.018_bb0035","doi-asserted-by":"crossref","first-page":"548154","DOI":"10.3389\/fped.2020.548154","article-title":"Management of children with fever at risk for pediatric sepsis: a prospective study in pediatric emergency care","volume":"8","author":"Nijman","year":"2020","journal-title":"Front Pediatr"},{"issue":"10","key":"10.1016\/j.ajem.2021.04.018_bb0040","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1097\/01.inf.0000091360.11784.21","article-title":"Procalcitonin in pediatric emergency departments for the early diagnosis of invasive bacterial infections in febrile infants: results of a multicenter study and utility of a rapid qualitative test for this marker","volume":"22","author":"Fern\u00e1ndez","year":"2003","journal-title":"Pediatr Infect Dis J"},{"issue":"3","key":"10.1016\/j.ajem.2021.04.018_bb0045","doi-asserted-by":"crossref","DOI":"10.1542\/peds.2020-1126","article-title":"Clinical prediction rule for distinguishing bacterial from aseptic meningitis","volume":"146","author":"Mintegi","year":"2020","journal-title":"Pediatrics"},{"key":"10.1016\/j.ajem.2021.04.018_bb0050","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1097\/MEJ.0b013e32831cefc9","article-title":"Predictors of occult bacteremia in young febrile children in the era of heptavalent pneumococcal conjugated vaccine","volume":"16","author":"Mintegi","year":"2009","journal-title":"Eur J Emerg Med"},{"key":"10.1016\/j.ajem.2021.04.018_bb0055","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1136\/adc.2010.203760","article-title":"Markers for bacterial infection in children with fever without source","volume":"96","author":"Manzano","year":"2011","journal-title":"Arch Dis Child"}],"updated-by":[{"DOI":"10.1016\/j.ajem.2021.04.052","type":"erratum","label":"Erratum","source":"publisher","updated":{"date-parts":[[2021,8,1]],"date-time":"2021-08-01T00:00:00Z","timestamp":1627776000000}}],"container-title":["The American Journal of Emergency Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0735675721003077?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0735675721003077?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T15:53:27Z","timestamp":1760025207000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0735675721003077"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,10]]},"references-count":11,"alternative-id":["S0735675721003077"],"URL":"https:\/\/doi.org\/10.1016\/j.ajem.2021.04.018","relation":{},"ISSN":["0735-6757"],"issn-type":[{"value":"0735-6757","type":"print"}],"subject":[],"published":{"date-parts":[[2021,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Markers for invasive bacterial infections in previously healthy children","name":"articletitle","label":"Article Title"},{"value":"The American Journal of Emergency Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajem.2021.04.018","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}