{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T21:29:51Z","timestamp":1790803791968,"version":"4.1.0"},"reference-count":23,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100007161","name":"Boston University","doi-asserted-by":"publisher","award":["CTSI 1UL1TR001430"],"award-info":[{"award-number":["CTSI 1UL1TR001430"]}],"id":[{"id":"10.13039\/100007161","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The American Journal of Emergency Medicine"],"published-print":{"date-parts":[[2021,11]]},"DOI":"10.1016\/j.ajem.2021.05.071","type":"journal-article","created":{"date-parts":[[2021,6,9]],"date-time":"2021-06-09T12:22:57Z","timestamp":1623241377000},"page":"226-232","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":31,"special_numbering":"C","title":["Impact of point-of-care ultrasound on treatment time for ectopic pregnancy"],"prefix":"10.1016","volume":"49","author":[{"given":"Bethsabee S.","family":"Stone","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Krithika M.","family":"Muruganandan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melinda M.","family":"Tonelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julianne N.","family":"Dugas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ivy E.","family":"Verriet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph R.","family":"Pare","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.ajem.2021.05.071_bb0005","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1097\/AOG.0b013e3182113c10","article-title":"Trends in ectopic pregnancy mortality in the United States: 1980-2007","volume":"117","author":"Creanga","year":"2011","journal-title":"Obstet. Gynecol."},{"key":"10.1016\/j.ajem.2021.05.071_bb0010","author":"Current Trends Ectopic Pregnancy -- United States"},{"issue":"4","key":"10.1016\/j.ajem.2021.05.071_bb0015","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1017\/S1481803500011416","article-title":"Diagnostic accuracy and clinical utility of emergency department targeted ultrasonography in the evaluation of first-trimester pelvic pain and bleeding: a systematic review","volume":"11","author":"McRae","year":"2009","journal-title":"CJEM"},{"issue":"3","key":"10.1016\/j.ajem.2021.05.071_bb0020","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/j.annemergmed.2006.01.008","article-title":"Randomized controlled clinical trial of point-of-care, limited ultrasonography for trauma in the emergency department: the first sonography outcomes assessment program trial","volume":"48","author":"Melniker","year":"2006","journal-title":"Ann. Emerg. Med."},{"key":"10.1016\/j.ajem.2021.05.071_bb0025","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1186\/1749-7922-2-23","article-title":"Ultrasound assessment of haemoperitoneum in ectopic pregnancy: derivation of a prediction model","volume":"2","author":"Fauconnier","year":"2007","journal-title":"World J Emerg Surg WJES"},{"issue":"2","key":"10.1016\/j.ajem.2021.05.071_bb0030","doi-asserted-by":"crossref","first-page":"307","DOI":"10.2214\/ajr.155.2.2115257","article-title":"Diagnosis of ectopic pregnancy: endovaginal vs transabdominal sonography","volume":"155","author":"Thorsen","year":"1990","journal-title":"Am. J. Roentgenol."},{"issue":"1","key":"10.1016\/j.ajem.2021.05.071_bb0035","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1053\/ajem.2002.30101","article-title":"Isolated fluid in the cul-de-sac: how well does it predict ectopic pregnancy?","volume":"20","author":"Dart","year":"2002","journal-title":"Am. J. Emerg. Med."},{"key":"10.1016\/j.ajem.2021.05.071_bb0040","doi-asserted-by":"crossref","DOI":"10.1155\/2020\/8874581","article-title":"Ultrasound measured depth of pelvic free fluid correlates well with blood loss volume in patients with ectopic pregnancy","volume":"2020","author":"Tang","year":"2020","journal-title":"Emerg Med Int"},{"issue":"4","key":"10.1016\/j.ajem.2021.05.071_bb0045","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1177\/875647939100700438","article-title":"Extrauterine findings of ectopic pregnancy at transvaginal US: importance of echogenic fluid","volume":"7","author":"Nyberg","year":"1991","journal-title":"J Diagn Med Sonogr"},{"issue":"4","key":"10.1016\/j.ajem.2021.05.071_bb0050","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1111\/j.1553-2712.2001.tb02110.x","article-title":"Emergency department right upper quadrant ultrasound is associated with a reduced time to diagnosis and treatment of ruptured ectopic pregnancies","volume":"8","author":"Rodgerson","year":"2001","journal-title":"Acad. Emerg. Med."},{"issue":"8","key":"10.1016\/j.ajem.2021.05.071_bb0055","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1197\/j.aem.2007.04.010","article-title":"Free fluid in Morison\u2019s pouch on bedside ultrasound predicts need for operative intervention in suspected ectopic pregnancy","volume":"14","author":"Moore","year":"2007","journal-title":"Acad. Emerg. Med. Off. J. Soc. Acad. Emerg. Med"},{"issue":"3","key":"10.1016\/j.ajem.2021.05.071_bb0060","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1016\/S0196-0644(96)70264-0","article-title":"Chart reviews in emergency medicine research: where are the methods?","volume":"27","author":"Gilbert","year":"1996","journal-title":"Ann. Emerg. Med."},{"issue":"3","key":"10.1016\/j.ajem.2021.05.071_bb0065","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1016\/j.annemergmed.2014.03.025","article-title":"Looking through the retrospectoscope: reducing bias in emergency medicine chart review studies","volume":"64","author":"Kaji","year":"2014","journal-title":"Ann. Emerg. Med."},{"issue":"2","key":"10.1016\/j.ajem.2021.05.071_bb0070","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1016\/j.jbi.2008.08.010","article-title":"Research electronic data capture (REDCap)\u2014a metadata-driven methodology and workflow process for providing translational research informatics support","volume":"42","author":"Harris","year":"2009","journal-title":"J. Biomed. Inform."},{"issue":"1","key":"10.1016\/j.ajem.2021.05.071_bb0075","doi-asserted-by":"crossref","first-page":"255","DOI":"10.2307\/2532051","article-title":"A concordance correlation coefficient to evaluate reproducibility","volume":"45","author":"Lin","year":"1989","journal-title":"Biometrics"},{"issue":"6","key":"10.1016\/j.ajem.2021.05.071_bb0080","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1016\/S0735-6757(03)00162-1","article-title":"Sensitivity in detecting free Intraperitoneal fluid with the pelvic views of the FAST exam","volume":"21","author":"Jehle","year":"2003","journal-title":"Am. J. Emerg. Med."},{"issue":"1","key":"10.1016\/j.ajem.2021.05.071_bb0085","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/S0196-0644(96)70131-2","article-title":"Ectopic pregnancy: prospective study with improved diagnostic accuracy","volume":"28","author":"Kaplan","year":"1996","journal-title":"Ann. Emerg. Med."},{"issue":"4","key":"10.1016\/j.ajem.2021.05.071_bb0090","first-page":"583","article-title":"Diagnostic accuracy of ultrasound above and below the beta-hCG discriminatory zone","volume":"94","author":"Barnhart","year":"1999","journal-title":"Obstet. Gynecol."},{"issue":"1","key":"10.1016\/j.ajem.2021.05.071_bb0095","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1097\/PEC.0b013e31827b53f9","article-title":"Does the use of bedside pelvic ultrasound decrease length of stay in the emergency department?","volume":"29","author":"Thamburaj","year":"2013","journal-title":"Pediatr. Emerg. Care"},{"issue":"9","key":"10.1016\/j.ajem.2021.05.071_bb0100","first-page":"912","article-title":"Outcome of patients with an indeterminate emergency department first-trimester pelvic ultrasound to rule out ectopic pregnancy","volume":"11","author":"Tayal","year":"2004","journal-title":"Acad. Emerg. Med."},{"issue":"2","key":"10.1016\/j.ajem.2021.05.071_bb0105","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.ijgo.2011.09.019","article-title":"Hemoperitoneum assessment in ectopic pregnancy","volume":"116","author":"Popowski","year":"2012","journal-title":"Int. J. Gynecol. Obstet."},{"key":"10.1016\/j.ajem.2021.05.071_bb0110","doi-asserted-by":"crossref","DOI":"10.1186\/s13326-017-0117-1","article-title":"Developing a knowledge base to support the annotation of ultrasound images of ectopic pregnancy","volume":"8","author":"Dhombres","year":"2017","journal-title":"J Biomed Semant"},{"issue":"5","key":"10.1016\/j.ajem.2021.05.071_bb0115","doi-asserted-by":"crossref","first-page":"e27","DOI":"10.1016\/j.annemergmed.2016.08.457","article-title":"Ultrasound guidelines: emergency, point-of-care and clinical ultrasound guidelines in medicine","volume":"69","year":"2017","journal-title":"Ann. Emerg. Med."}],"container-title":["The American Journal of Emergency Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0735675721004551?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0735675721004551?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T15:55:50Z","timestamp":1760025350000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0735675721004551"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11]]},"references-count":23,"alternative-id":["S0735675721004551"],"URL":"https:\/\/doi.org\/10.1016\/j.ajem.2021.05.071","relation":{},"ISSN":["0735-6757"],"issn-type":[{"value":"0735-6757","type":"print"}],"subject":[],"published":{"date-parts":[[2021,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Impact of point-of-care ultrasound on treatment time for ectopic pregnancy","name":"articletitle","label":"Article Title"},{"value":"The American Journal of Emergency Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajem.2021.05.071","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}