{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,28]],"date-time":"2026-03-28T16:01:14Z","timestamp":1774713674148,"version":"3.50.1"},"reference-count":28,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The American Journal of Emergency Medicine"],"published-print":{"date-parts":[[2023,1]]},"DOI":"10.1016\/j.ajem.2022.10.026","type":"journal-article","created":{"date-parts":[[2022,10,21]],"date-time":"2022-10-21T12:20:11Z","timestamp":1666354811000},"page":"69-73","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"special_numbering":"C","title":["Diagnostic value of end-tidal carbon dioxide in the differential diagnosis of unstable angina and non-cardiac chest pain"],"prefix":"10.1016","volume":"63","author":[{"given":"Murat","family":"Duyan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nafis","family":"Vural","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ajem.2022.10.026_bb0005","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1093\/eurheartj\/ehx393","volume":"39","author":"Ibanez","year":"2018","journal-title":"Eur Heart J"},{"key":"10.1016\/j.ajem.2022.10.026_bb0010","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1161\/CIR.0000000000000366","article-title":"Executive summary: heart disease and stroke statistics\u20142016 update","volume":"133","author":"Mozaffarian","year":"2016","journal-title":"Circulation."},{"key":"10.1016\/j.ajem.2022.10.026_bb0015","doi-asserted-by":"crossref","first-page":"432","DOI":"10.3325\/cmj.2012.53.432","article-title":"Does the patient with chest pain have a coronary heart disease? Diagnostic value of single symptoms and signs \u2013 a meta-analysis","volume":"53","author":"Haasenritter","year":"2012","journal-title":"Croat Med J"},{"key":"10.1016\/j.ajem.2022.10.026_bb0020","doi-asserted-by":"crossref","first-page":"2696","DOI":"10.1093\/eurheartj\/ehv428","article-title":"Cardiovascular disease in Europe--epidemiological update 2015","volume":"36","author":"Townsend","year":"2015","journal-title":"Eur Heart J"},{"key":"10.1016\/j.ajem.2022.10.026_bb0025","first-page":"1","article-title":"Global atlas on cardiovascular disease prevention and control","author":"Mendis","year":"2011","journal-title":"Jt Publ World Heal Organ World Hear Fed World Stroke Organ"},{"key":"10.1016\/j.ajem.2022.10.026_bb0030","author":"Rui"},{"key":"10.1016\/j.ajem.2022.10.026_bb0035","first-page":"33","article-title":"How to use high-sensitivity cardiac troponins in acute cardiac care","author":"Thygesen","year":"2012","journal-title":"Eur Heart J"},{"key":"10.1016\/j.ajem.2022.10.026_bb0040","doi-asserted-by":"crossref","first-page":"1581","DOI":"10.1016\/j.jacc.2012.08.001","article-title":"Third universal definition of myocardial infarction","volume":"60","author":"Thygesen","year":"2012","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.ajem.2022.10.026_bb0045","doi-asserted-by":"crossref","first-page":"S12","DOI":"10.1016\/j.jelectrocard.2018.08.018","article-title":"Criteria for ECG detection of acute myocardial ischemia: sensitivity versus specificity","volume":"51","author":"Wang","year":"2018","journal-title":"J Electrocardiol"},{"key":"10.1016\/j.ajem.2022.10.026_bb0050","first-page":"11","article-title":"Past, present, and future of blood biomarkers for the diagnosis of acute myocardial infarction\u2014promises and challenges","author":"Tilea","year":"2021","journal-title":"Diagnostics."},{"key":"10.1016\/j.ajem.2022.10.026_bb0055","doi-asserted-by":"crossref","first-page":"1289","DOI":"10.1093\/eurheartj\/ehaa575","article-title":"2020 ESC guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation","volume":"42","author":"Collet","year":"2021","journal-title":"Eur Heart J"},{"key":"10.1016\/j.ajem.2022.10.026_bb0060","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1016\/j.ajem.2022.08.058","article-title":"The difference between arterial pCO2 and etCO2 after cardiac arrest \u2013 outcome predictor or marker of unfavorable resuscitation circumstances?","volume":"61","author":"Mueller","year":"2022","journal-title":"Am J Emerg Med"},{"key":"10.1016\/j.ajem.2022.10.026_bb0065","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.resuscitation.2017.12.003","article-title":"The use of end-tidal carbon dioxide (ETCO 2) measurement to guide management of cardiac arrest: a systematic review","volume":"123","author":"Paiva","year":"2018","journal-title":"Resuscitation."},{"key":"10.1016\/j.ajem.2022.10.026_bb0070","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1097\/01.MLR.0000062554.74615.4C","article-title":"Interpretation of changes in health-related quality of life: the remarkable universality of half a standard deviation","volume":"41","author":"Norman","year":"2003","journal-title":"Med Care"},{"key":"10.1016\/j.ajem.2022.10.026_bb0075","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1007\/s10459-010-9222-y","article-title":"Likert scales, levels of measurement and the \u201claws\u201d of statistics","volume":"15","author":"Norman","year":"2010","journal-title":"Adv Health Sci Educ Theory Pract"},{"key":"10.1016\/j.ajem.2022.10.026_bb0080","doi-asserted-by":"crossref","first-page":"e139","DOI":"10.1016\/j.jacc.2014.09.017","article-title":"2014 AHA\/ACC guideline for the management of patients with non-ST-elevation acute coronary syndromes: a report of the American College of Cardiology\/American Heart Association Task Force on Practice Guidelines","volume":"64","author":"Amsterdam","year":"2014","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.ajem.2022.10.026_bb0085","doi-asserted-by":"crossref","first-page":"e618","DOI":"10.1161\/CIR.0000000000000617","article-title":"Fourth universal definition of myocardial infarction (2018)","volume":"138","author":"Thygesen","year":"2018","journal-title":"Circulation."},{"key":"10.1016\/j.ajem.2022.10.026_bb0090","first-page":"4","article-title":"The role of biomarkers in the diagnosis and risk stratification of acute coronary syndrome","author":"Chacko","year":"2018","journal-title":"Futur Sci OA"},{"key":"10.1016\/j.ajem.2022.10.026_bb0095","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1253\/circj.CJ-09-0484","article-title":"Upregulation of fractalkine and its receptor, CX3CR1, is associated with coronary plaque rupture in patients with unstable angina pectoris","volume":"74","author":"Ikejima","year":"2010","journal-title":"Circ J"},{"key":"10.1016\/j.ajem.2022.10.026_bb0100","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1111\/1440-1681.12302","article-title":"Circulating CD36 and fractalkine levels are associated with vulnerable plaque progression in patients with unstable angina pectoris","volume":"41","author":"Li","year":"2014","journal-title":"Clin Exp Pharmacol Physiol"},{"key":"10.1016\/j.ajem.2022.10.026_bb0105","first-page":"231","article-title":"Relationship between high-sensitivity C-reactive protein serum levels and the severity of coronary artery stenosis in patients with coronary artery disease","volume":"12","author":"Seyedian","year":"2016","journal-title":"ARYA Atheroscler"},{"key":"10.1016\/j.ajem.2022.10.026_bb0110","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/j.jjcc.2008.12.007","article-title":"Inflammatory biomarkers in coronary artery disease","volume":"53","author":"Zakynthinos","year":"2009","journal-title":"J Cardiol"},{"key":"10.1016\/j.ajem.2022.10.026_bb0115","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1080\/1354750X.2020.1841293","article-title":"One fits all hs troponin or more personalized dual markers strategies in the primary diagnostic assessment of patients with suspected acute coronary syndrome?","volume":"25","author":"M\u00f6ckel","year":"2020","journal-title":"Biomarkers."},{"key":"10.1016\/j.ajem.2022.10.026_bb0120","first-page":"120","article-title":"High-sensitivity cardiac troponin assays and unstable angina","volume":"7","author":"Sandoval","year":"2018","journal-title":"Eur Hear J Acute Cardiovasc Care"},{"key":"10.1016\/j.ajem.2022.10.026_bb0125","doi-asserted-by":"crossref","first-page":"1207","DOI":"10.1056\/NEJM200004203421610","article-title":"Missed diagnoses of acute coronary syndromes in the emergency room--continuing challenges","volume":"342","author":"Mehta","year":"2000","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ajem.2022.10.026_bb0130","article-title":"Applications of end-tidal carbon dioxide (ETCO2) monitoring in emergency department; a narrative review","volume":"6","author":"Aminiahidashti","year":"2018","journal-title":"Emergency"},{"key":"10.1016\/j.ajem.2022.10.026_bb0135","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.resuscitation.2018.08.018","article-title":"Capnography during cardiac arrest","volume":"132","author":"Sandroni","year":"2018","journal-title":"Resuscitation."},{"key":"10.1016\/j.ajem.2022.10.026_bb0140","doi-asserted-by":"crossref","first-page":"2501","DOI":"10.1053\/j.jvca.2019.10.005","article-title":"The pathophysiology of myocardial ischemia and perioperative myocardial infarction","volume":"34","author":"Smit","year":"2020","journal-title":"J Cardiothorac Vasc Anesth"}],"container-title":["The American Journal of Emergency Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S073567572200660X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S073567572200660X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T16:03:13Z","timestamp":1760025793000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S073567572200660X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1]]},"references-count":28,"alternative-id":["S073567572200660X"],"URL":"https:\/\/doi.org\/10.1016\/j.ajem.2022.10.026","relation":{},"ISSN":["0735-6757"],"issn-type":[{"value":"0735-6757","type":"print"}],"subject":[],"published":{"date-parts":[[2023,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Diagnostic value of end-tidal carbon dioxide in the differential diagnosis of unstable angina and non-cardiac chest pain","name":"articletitle","label":"Article Title"},{"value":"The American Journal of Emergency Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajem.2022.10.026","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}