{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T00:47:48Z","timestamp":1760057268784,"version":"build-2065373602"},"reference-count":5,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The American Journal of Emergency Medicine"],"published-print":{"date-parts":[[2023,8]]},"DOI":"10.1016\/j.ajem.2023.07.003","type":"journal-article","created":{"date-parts":[[2023,7,3]],"date-time":"2023-07-03T21:02:56Z","timestamp":1688418176000},"page":"183-184","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["The elimination half-life of metformin during metformin overdose"],"prefix":"10.1016","volume":"70","author":[{"given":"Ju-Tae","family":"Sohn","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ajem.2023.07.003_bb0005","doi-asserted-by":"crossref","DOI":"10.1016\/j.ajem.2023.02.038","article-title":"Toxicokinetics of metformin overdose treated with CVVHDF","author":"Lewis","year":"2023","journal-title":"Am J Emerg Med"},{"key":"10.1016\/j.ajem.2023.07.003_bb0010","doi-asserted-by":"crossref","first-page":"103996","DOI":"10.1016\/j.biosystems.2019.103996","article-title":"Estimating a drug\u2019s elimination rate-constant or half-life from a single blood sample: a practical approach with particular benefits for critically ill\/vulnerable patients","volume":"184","author":"Scutt","year":"2019","journal-title":"Biosystems"},{"key":"10.1016\/j.ajem.2023.07.003_bb0015","doi-asserted-by":"crossref","first-page":"359","DOI":"10.2165\/00003088-199630050-00003","article-title":"Clinical pharmacokinetics of metformin","volume":"30","author":"Scheen","year":"1996","journal-title":"Clin Pharmacokinet"},{"key":"10.1016\/j.ajem.2023.07.003_bb0020","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1111\/dme.12959","article-title":"Unexpectedly long half-life of metformin elimination in cases of metformin accumulation","volume":"33","author":"Kajbaf","year":"2016","journal-title":"Diabet Med"},{"key":"10.1016\/j.ajem.2023.07.003_bb0025","first-page":"447","article-title":"Therapeutic and toxic blood concentrations of more than 800 drugs and other xenobiotics","volume":"58","author":"Schulz","year":"2003","journal-title":"Pharmazie"}],"container-title":["The American Journal of Emergency Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0735675723003492?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0735675723003492?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T16:07:42Z","timestamp":1760026062000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0735675723003492"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,8]]},"references-count":5,"alternative-id":["S0735675723003492"],"URL":"https:\/\/doi.org\/10.1016\/j.ajem.2023.07.003","relation":{},"ISSN":["0735-6757"],"issn-type":[{"type":"print","value":"0735-6757"}],"subject":[],"published":{"date-parts":[[2023,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The elimination half-life of metformin during metformin overdose","name":"articletitle","label":"Article Title"},{"value":"The American Journal of Emergency Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajem.2023.07.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"simple-article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}