{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,6,19]],"date-time":"2024-06-19T07:56:34Z","timestamp":1718783794379},"reference-count":8,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The American Journal of Emergency Medicine"],"published-print":{"date-parts":[[2024,6]]},"DOI":"10.1016\/j.ajem.2024.04.023","type":"journal-article","created":{"date-parts":[[2024,4,21]],"date-time":"2024-04-21T02:35:04Z","timestamp":1713666904000},"page":"231.e1-231.e2","update-policy":"http:\/\/dx.doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["Amifampridine overdose leading to refractory status epilepticus"],"prefix":"10.1016","volume":"80","author":[{"given":"Brian","family":"Gooley","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ben","family":"Willenbring","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jenna","family":"Wilkinson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ajem.2024.04.023_bb0005","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1007\/s13181-012-0248-9","article-title":"4-aminopyridine toxicity: a case report and review of the literature","volume":"8","author":"King","year":"2012","journal-title":"J Med Toxicol"},{"key":"10.1016\/j.ajem.2024.04.023_bb0010","doi-asserted-by":"crossref","first-page":"583","DOI":"10.3109\/15563659409011063","article-title":"Characterization of 4-aminopyridine in overdose","volume":"32","author":"Stork","year":"1994","journal-title":"J Toxicol Clin Toxicol"},{"key":"10.1016\/j.ajem.2024.04.023_bb0015","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1113\/jphysiol.1981.sp013666","article-title":"The effects of 4-aminopyridine and tetraethylammonium ions on normal and demyelinated mammalian nerve fibres","volume":"313","author":"Bostock","year":"1981","journal-title":"J Physiol"},{"key":"10.1016\/j.ajem.2024.04.023_bb0020","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1007\/BF00386054","article-title":"Improvement in neuromuscular transmission in myasthenia gravis by 3,4-diaminopyridine","volume":"234","author":"Lundh","year":"1985","journal-title":"Eur Arch Psychiatry Neurol Sci"},{"key":"10.1016\/j.ajem.2024.04.023_bb0025","first-page":"329","article-title":"Clinical signs and chemical confirmation of 4-aminopyridine poisoning in horses","volume":"39","author":"Ray","year":"1978","journal-title":"Am J Vet Res"},{"key":"10.1016\/j.ajem.2024.04.023_bb0030","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/0920-1211(92)90016-M","article-title":"Effects of anticonvulsant drugs on 4-aminopyridine-induced seizures in mice","volume":"11","author":"Yamaguchi","year":"1992","journal-title":"Epilepsy Res"},{"key":"10.1016\/j.ajem.2024.04.023_bb0035","series-title":"Goldfrank\u2019s toxicologic emergencies","author":"Nelson","year":"2018"},{"key":"10.1016\/j.ajem.2024.04.023_bb0040","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1177\/1756285613512712","article-title":"4-Aminopyridine for symptomatic treatment of multiple sclerosis: a systematic review","volume":"7","author":"Jensen","year":"2014","journal-title":"Ther Adv Neurol Disord"}],"container-title":["The American Journal of Emergency Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0735675724001797?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0735675724001797?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,5,28]],"date-time":"2024-05-28T07:58:58Z","timestamp":1716883138000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0735675724001797"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6]]},"references-count":8,"alternative-id":["S0735675724001797"],"URL":"https:\/\/doi.org\/10.1016\/j.ajem.2024.04.023","relation":{},"ISSN":["0735-6757"],"issn-type":[{"value":"0735-6757","type":"print"}],"subject":[],"published":{"date-parts":[[2024,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Amifampridine overdose leading to refractory status epilepticus","name":"articletitle","label":"Article Title"},{"value":"The American Journal of Emergency Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajem.2024.04.023","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}