{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,24]],"date-time":"2026-01-24T15:53:36Z","timestamp":1769270016002,"version":"3.49.0"},"reference-count":20,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The American Journal of Emergency Medicine"],"published-print":{"date-parts":[[2025,8]]},"DOI":"10.1016\/j.ajem.2025.04.052","type":"journal-article","created":{"date-parts":[[2025,4,28]],"date-time":"2025-04-28T23:05:57Z","timestamp":1745881557000},"page":"192-196","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["Utilization of full-agonist therapy for severe precipitated opioid withdrawal: A case series and retrospective analysis"],"prefix":"10.1016","volume":"94","author":[{"given":"Amar","family":"Chakraborty","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Annika","family":"Strand","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brian","family":"Gooley","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jenna","family":"LeRoy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sean","family":"Boley","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ajem.2025.04.052_bb0005","series-title":"Overdose Deaths Decrease 2023, First Time Since 2018","volume":"14","author":"Cdc US","year":"2018"},{"key":"10.1016\/j.ajem.2025.04.052_bb0010","series-title":"Drug overdose deaths in the United States, 2002\u20132022","author":"Spencer","year":"2023"},{"key":"10.1016\/j.ajem.2025.04.052_bb0020","doi-asserted-by":"crossref","first-page":"59","DOI":"10.2147\/SAR.S433358","article-title":"Managing opioid withdrawal symptoms during the fentanyl crisis: a review","volume":"15","author":"Weber","year":"2024","journal-title":"Subst Abuse Rehabil"},{"key":"10.1016\/j.ajem.2025.04.052_bb0025","article-title":"Emergency department-initiated buprenorphine protocols: a national evaluation","volume":"2","author":"Guo","year":"2021","journal-title":"J Am Coll Emerg Physicians Open"},{"key":"10.1016\/j.ajem.2025.04.052_bb0030","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1016\/j.annemergmed.2018.11.032","article-title":"Managing opioid withdrawal in the emergency department with buprenorphine","volume":"73","author":"Herring","year":"2019","journal-title":"Ann Emerg Med"},{"key":"10.1016\/j.ajem.2025.04.052_bb0035","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.ajem.2022.05.013","article-title":"Buprenorphine precipitated opioid withdrawal: prevention and management in the ED setting","volume":"58","author":"Spadaro","year":"2022","journal-title":"Am J Emerg Med"},{"key":"10.1016\/j.ajem.2025.04.052_bb0040","doi-asserted-by":"crossref","first-page":"2540","DOI":"10.1111\/add.15818","article-title":"Clinical management of opioid withdrawal","volume":"117","author":"Torres-Lockhart","year":"2022","journal-title":"Addiction"},{"key":"10.1016\/j.ajem.2025.04.052_bb0045","doi-asserted-by":"crossref","first-page":"1938","DOI":"10.1016\/S0140-6736(20)30852-7","article-title":"New directions in the treatment of opioid withdrawal","volume":"395","author":"Srivastava","year":"2020","journal-title":"Lancet"},{"key":"10.1016\/j.ajem.2025.04.052_bb0050","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1002\/jhm.13238","article-title":"Point\/counterpoint: should full agonist opioid medications be offered to hospitalized patients for management of opioid withdrawal?","volume":"19","author":"Stern","year":"2024","journal-title":"J Hosp Med"},{"key":"10.1016\/j.ajem.2025.04.052_bb0055","doi-asserted-by":"crossref","first-page":"E512","DOI":"10.1001\/amajethics.2024.512","article-title":"How should risks and benefits of short-acting opioids be evaluated in the care of inpatients with OUD?","volume":"26","author":"Dong","year":"2024","journal-title":"AMA J Ethics"},{"key":"10.1016\/j.ajem.2025.04.052_bb0060","doi-asserted-by":"crossref","first-page":"E1718","DOI":"10.1503\/cmaj.230968","article-title":"Using short-acting opioids to relieve opioid withdrawal in hospital","volume":"195","author":"Kleinman","year":"2023","journal-title":"CMAJ: Canadian Medical Association Journal"},{"key":"10.1016\/j.ajem.2025.04.052_bb0065","doi-asserted-by":"crossref","first-page":"283","DOI":"10.7326\/M21-3968","article-title":"Treating opioid withdrawal in the hospital: a role for short-acting opioids","volume":"175","author":"Kleinman","year":"2022","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.ajem.2025.04.052_bb0070","series-title":"Perioperative management of opioid use disorder patients on buprenorphine\/naloxone","author":"Tung","year":"2025"},{"key":"10.1016\/j.ajem.2025.04.052_bb0075","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1111\/dar.13394","article-title":"Challenges with buprenorphine inductions in the context of the fentanyl overdose crisis: a case series","volume":"41","author":"Shearer","year":"2022","journal-title":"Drug Alcohol Rev"},{"key":"10.1016\/j.ajem.2025.04.052_bb0080","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1186\/s13722-023-00368-z","article-title":"Safety and preliminary outcomes of short-acting opioid agonist treatment (sOAT) for hospitalized patients with opioid use disorder","volume":"18","author":"Thakrar","year":"2023","journal-title":"Addict Sci Clin Pract"},{"key":"10.1016\/j.ajem.2025.04.052_bb0085","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/j.drugalcdep.2009.07.001","article-title":"Concurrent validation of the Clinical Opiate Withdrawal Scale (COWS) and single-item indices against the Clinical Institute Narcotic Assessment (CINA) opioid withdrawal instrument","volume":"105","author":"Tompkins","year":"2009","journal-title":"Drug Alcohol Depend"},{"key":"10.1016\/j.ajem.2025.04.052_bb0090","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.annemergmed.2019.04.006","article-title":"Pulmonary complications of opioid overdose treated with naloxone","volume":"75","author":"Farkas","year":"2020","journal-title":"Ann Emerg Med"},{"key":"10.1016\/j.ajem.2025.04.052_bb0095","series-title":"Information about Medications for Opioid Use Disorder (MOUD)","author":"Center for Drug Evaluation, Research","year":"2024"},{"key":"10.1016\/j.ajem.2025.04.052_bb0100","series-title":"FDA approves the first non-opioid treatment for management of opioid withdrawal symptoms in adults","author":"Office of the Commissioner","year":"2020"},{"key":"10.1016\/j.ajem.2025.04.052_bb0105","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1111\/ajad.13135","article-title":"Microinduction of buprenorphine\/naloxone: a review of the literature","volume":"30","author":"Ahmed","year":"2021","journal-title":"Am J Addict"}],"container-title":["The American Journal of Emergency Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0735675725002931?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0735675725002931?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,6,26]],"date-time":"2025-06-26T16:37:53Z","timestamp":1750955873000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0735675725002931"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8]]},"references-count":20,"alternative-id":["S0735675725002931"],"URL":"https:\/\/doi.org\/10.1016\/j.ajem.2025.04.052","relation":{},"ISSN":["0735-6757"],"issn-type":[{"value":"0735-6757","type":"print"}],"subject":[],"published":{"date-parts":[[2025,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Utilization of full-agonist therapy for severe precipitated opioid withdrawal: A case series and retrospective analysis","name":"articletitle","label":"Article Title"},{"value":"The American Journal of Emergency Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajem.2025.04.052","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}