{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T01:08:10Z","timestamp":1793149690420,"version":"4.5.0"},"reference-count":14,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T00:00:00Z","timestamp":1785196800000},"content-version":"am","delay-in-days":269,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006108","name":"National Center for Advancing Translational Sciences","doi-asserted-by":"publisher","award":["UL1TR002548"],"award-info":[{"award-number":["UL1TR002548"]}],"id":[{"id":"10.13039\/100006108","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The American Journal of Emergency Medicine"],"published-print":{"date-parts":[[2025,11]]},"DOI":"10.1016\/j.ajem.2025.07.056","type":"journal-article","created":{"date-parts":[[2025,7,24]],"date-time":"2025-07-24T15:08:58Z","timestamp":1753369738000},"page":"147-151","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"special_numbering":"C","title":["External validation of a widely available, localizable sepsis early detection model in the emergency department setting"],"prefix":"10.1016","volume":"97","author":[{"given":"Danielle","family":"Currey","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasir","family":"Tarabichi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"11","key":"10.1016\/j.ajem.2025.07.056_bb0005","doi-asserted-by":"crossref","first-page":"e1063","DOI":"10.1097\/CCM.0000000000005337","article-title":"Surviving sepsis campaign: international guidelines for Management of Sepsis and Septic Shock 2021","volume":"49","author":"Evans","year":"2021","journal-title":"Crit Care Med"},{"issue":"1","key":"10.1016\/j.ajem.2025.07.056_bb0010","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41746-022-00650-5","article-title":"Effectiveness of automated alerting system compared to usual care for the management of sepsis","volume":"5","author":"Zhang","year":"2022","journal-title":"Npj Digit Med"},{"issue":"299","key":"10.1016\/j.ajem.2025.07.056_bb0015","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.aab3719","article-title":"A targeted real-time early warning score (TREWScore) for septic shock","volume":"7","author":"Henry","year":"2015","journal-title":"Sci Transl Med"},{"issue":"4","key":"10.1016\/j.ajem.2025.07.056_bb0020","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1016\/j.annemergmed.2018.11.036","article-title":"Development and evaluation of a machine learning model for the early identification of patients at risk for sepsis","volume":"73","author":"Delahanty","year":"2019","journal-title":"Ann Emerg Med"},{"issue":"4","key":"10.1016\/j.ajem.2025.07.056_bb0025","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1038\/s42256-023-00638-0","article-title":"Estimating treatment effects for time-to-treatment antibiotic stewardship in sepsis","volume":"5","author":"Liu","year":"2023","journal-title":"Nat Mach Intell"},{"key":"10.1016\/j.ajem.2025.07.056_bb0030","doi-asserted-by":"crossref","DOI":"10.1513\/AnnalsATS.201603-172BC","article-title":"The nature and variability of automated practice alerts derived from electronic health records in a U.S. Nationwide Critical Care Research Network","author":"Benthin","year":"2016","journal-title":"Ann Am Thorac Soc"},{"issue":"8","key":"10.1016\/j.ajem.2025.07.056_bb0035","doi-asserted-by":"crossref","first-page":"1065","DOI":"10.1001\/jamainternmed.2021.2626","article-title":"External validation of a widely implemented proprietary sepsis prediction model in hospitalized patients","volume":"181","author":"Wong","year":"2021","journal-title":"JAMA Intern Med"},{"issue":"3","key":"10.1016\/j.ajem.2025.07.056_bb0040","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1097\/CCM.0000000000005267","article-title":"Improving timeliness of antibiotic administration using a provider and pharmacist facing sepsis early warning system in the emergency department setting: a randomized controlled quality improvement initiative","volume":"50","author":"Tarabichi","year":"2022","journal-title":"Crit Care Med"},{"issue":"6","key":"10.1016\/j.ajem.2025.07.056_bb0045","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1001\/jamainternmed.2022.7182","article-title":"Factors associated with variability in the performance of a proprietary sepsis prediction model across 9 networked hospitals in the US","volume":"183","author":"Lyons","year":"2023","journal-title":"JAMA Intern Med"},{"issue":"3","key":"10.1016\/j.ajem.2025.07.056_bb0050","doi-asserted-by":"crossref","DOI":"10.1056\/AIoa2300032","article-title":"Evaluation of sepsis prediction models before onset of treatment","volume":"1","author":"Kamran","year":"2024","journal-title":"NEJM AI"},{"issue":"5","key":"10.1016\/j.ajem.2025.07.056_bb0055","doi-asserted-by":"crossref","first-page":"1649","DOI":"10.1097\/CCM.0b013e31819def97","article-title":"The sequential organ failure assessment score for predicting outcome in patients with severe sepsis and evidence of hypoperfusion at the time of emergency department presentation*","volume":"37","author":"Jones","year":"2009","journal-title":"Crit Care Med"},{"issue":"8","key":"10.1016\/j.ajem.2025.07.056_bb0060","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1001\/jama.2016.0288","article-title":"Assessment of clinical criteria for sepsis: for the third international consensus definitions for sepsis and septic shock (Sepsis-3)","volume":"315","author":"Seymour","year":"2016","journal-title":"JAMA"},{"key":"10.1016\/j.ajem.2025.07.056_bb0065","author":"R Core Team"},{"issue":"3","key":"10.1016\/j.ajem.2025.07.056_bb0070","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1109\/MCSE.2007.55","article-title":"Matplotlib: a 2D graphics environment","volume":"9","author":"Hunter","year":"2007","journal-title":"Comput Sci Eng"}],"updated-by":[{"DOI":"10.1016\/j.ajem.2025.08.029","type":"erratum","label":"Erratum","source":"publisher","updated":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000}}],"container-title":["The American Journal of Emergency Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0735675725005170?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0735675725005170?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T00:49:06Z","timestamp":1772758146000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0735675725005170"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11]]},"references-count":14,"alternative-id":["S0735675725005170"],"URL":"https:\/\/doi.org\/10.1016\/j.ajem.2025.07.056","relation":{},"ISSN":["0735-6757"],"issn-type":[{"value":"0735-6757","type":"print"}],"subject":[],"published":{"date-parts":[[2025,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"External validation of a widely available, localizable sepsis early detection model in the emergency department setting","name":"articletitle","label":"Article Title"},{"value":"The American Journal of Emergency Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajem.2025.07.056","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}