{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T12:26:23Z","timestamp":1789907183415,"version":"4.0.1"},"reference-count":9,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The American Journal of Emergency Medicine"],"published-print":{"date-parts":[[2025,12]]},"DOI":"10.1016\/j.ajem.2025.08.017","type":"journal-article","created":{"date-parts":[[2025,8,12]],"date-time":"2025-08-12T15:37:00Z","timestamp":1755013020000},"page":"41-45","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"special_numbering":"C","title":["Low versus high dosing strategies of intravenous nitroglycerin for the management of sympathetic crashing acute pulmonary edema"],"prefix":"10.1016","volume":"98","author":[{"given":"Kyle","family":"Henry","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brittany","family":"Pelsue","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heather","family":"Hartman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian","family":"Gulbis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1 Pt 2","key":"10.1016\/j.ajem.2025.08.017_bb0005","first-page":"216","article-title":"Hemodynamic effects of nitroglycerin and long-acting nitrates","volume":"110","author":"Abrams","year":"1985","journal-title":"Am Heart J"},{"issue":"18","key":"10.1016\/j.ajem.2025.08.017_bb0010","first-page":"e876","article-title":"2022 AHA\/ACC\/HFSA guideline for the Management of Heart Failure: executive summary: a report of the American College of Cardiology\/American Heart Association joint committee on clinical practice guidelines","volume":"145","author":"Heidenreich","year":"2022","journal-title":"Circulation"},{"key":"10.1016\/j.ajem.2025.08.017_bb0015","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.ajem.2022.12.022","article-title":"Low- versus high-dose nitroglycerin infusion in the management of acute pulmonary edema","volume":"65","author":"Kelly","year":"2023","journal-title":"Am J Emerg Med"},{"issue":"2","key":"10.1016\/j.ajem.2025.08.017_bb0020","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1016\/j.annemergmed.2007.02.022","article-title":"Treatment of severe decompensated heart failure with high-dose intravenous nitroglycerin: a feasibility and outcome analysis","volume":"50","author":"Levy","year":"2007","journal-title":"Ann Emerg Med"},{"issue":"3","key":"10.1016\/j.ajem.2025.08.017_bb0025","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/j.jemermed.2021.05.011","article-title":"High-dose nitroglycerin bolus for sympathetic crashing acute pulmonary edema: a prospective observational pilot study","volume":"61","author":"Mathew","year":"2021","journal-title":"J Emerg Med"},{"issue":"3","key":"10.1016\/j.ajem.2025.08.017_bb0030","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/j.pcad.2009.10.002","article-title":"Flash pulmonary edema","volume":"52","author":"Rimoldi","year":"2009","journal-title":"Prog Cardiovasc Dis"},{"issue":"2","key":"10.1016\/j.ajem.2025.08.017_bb0035","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1136\/emermed-2023-213285","article-title":"High-dose versus low-dose intravenous nitroglycerine for sympathetic crashing acute pulmonary edema: a randomised controlled trial","volume":"41","author":"Siddiqua","year":"2024","journal-title":"Emerg Med J"},{"issue":"3B","key":"10.1016\/j.ajem.2025.08.017_bb0040","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/0002-9343(87)90208-7","article-title":"Effects of antihypertensive treatment on cerebral perfusion","volume":"82","author":"Bertel","year":"1987","journal-title":"Am J Med"},{"key":"10.1016\/j.ajem.2025.08.017_bb0045","author":"The jamovi project"}],"container-title":["The American Journal of Emergency Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0735675725005479?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0735675725005479?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T22:17:46Z","timestamp":1768429066000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0735675725005479"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12]]},"references-count":9,"alternative-id":["S0735675725005479"],"URL":"https:\/\/doi.org\/10.1016\/j.ajem.2025.08.017","relation":{},"ISSN":["0735-6757"],"issn-type":[{"value":"0735-6757","type":"print"}],"subject":[],"published":{"date-parts":[[2025,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Low versus high dosing strategies of intravenous nitroglycerin for the management of sympathetic crashing acute pulmonary edema","name":"articletitle","label":"Article Title"},{"value":"The American Journal of Emergency Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajem.2025.08.017","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}