{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T11:15:32Z","timestamp":1788779732650,"version":"build-2803163510"},"reference-count":35,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The American Journal of Emergency Medicine"],"published-print":{"date-parts":[[2026,1]]},"DOI":"10.1016\/j.ajem.2025.09.046","type":"journal-article","created":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T19:10:23Z","timestamp":1758827423000},"page":"207-214","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["Prognostic value of the lactate-to-albumin ratio for in-hospital mortality in severe acute pancreatitis with acute kidney injury: A retrospective cohort study"],"prefix":"10.1016","volume":"99","author":[{"given":"Qingcheng","family":"Zhu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ping","family":"Geng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bingyu","family":"Ling","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Koumei","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ajem.2025.09.046_bb0005","doi-asserted-by":"crossref","first-page":"ITC17","DOI":"10.7326\/AITC202102160","article-title":"Acute pancreatitis","volume":"174","author":"Gardner","year":"2021","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.ajem.2025.09.046_bb0010","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijmedinf.2021.104641","article-title":"Machine learning predictive models for acute pancreatitis: a systematic review","volume":"157","author":"Zhou","year":"2022","journal-title":"Int J Med Inform"},{"key":"10.1016\/j.ajem.2025.09.046_bb0015","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1111\/den.13470","article-title":"Superiority of endoscopic interventions over minimally invasive surgery for infected necrotizing pancreatitis: meta-analysis of randomized trials","volume":"32","author":"Bang","year":"2020","journal-title":"Dig Endosc"},{"key":"10.1016\/j.ajem.2025.09.046_bb0020","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1186\/s12882-023-03369-x","article-title":"Construction and validation of a risk assessment model for acute kidney injury in patients with acute pancreatitis in the intensive care unit","volume":"24","author":"Jiang","year":"2023","journal-title":"BMC Nephrol"},{"key":"10.1016\/j.ajem.2025.09.046_bb0025","doi-asserted-by":"crossref","DOI":"10.1080\/0886022X.2023.2194436","article-title":"Development and validation of a prediction model for the early occurrence of acute kidney injury in patients with acute pancreatitis","volume":"45","author":"Wu","year":"2023","journal-title":"Ren Fail"},{"key":"10.1016\/j.ajem.2025.09.046_bb0030","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1111\/nep.12439","article-title":"Effect of acute kidney injury on mortality and hospital stay in patient with severe acute pancreatitis","volume":"20","author":"Zhou","year":"2015","journal-title":"Nephrology (Carlton)"},{"key":"10.1016\/j.ajem.2025.09.046_bb0035","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1080\/08941939.2018.1453891","article-title":"Acute kidney injury in critically ill patients with sepsis: clinical characteristics and outcomes","volume":"32","author":"Zhi","year":"2019","journal-title":"J Invest Surg"},{"key":"10.1016\/j.ajem.2025.09.046_bb0040","doi-asserted-by":"crossref","first-page":"5268","DOI":"10.3748\/wjg.v29.i37.5268","article-title":"Acute pancreatitis: a review of diagnosis, severity prediction and prognosis assessment from imaging technology, scoring system and artificial intelligence","volume":"29","author":"Hu","year":"2023","journal-title":"World J Gastroenterol"},{"key":"10.1016\/j.ajem.2025.09.046_bb0045","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2022.1076121","article-title":"Association between lactate-to-albumin ratio and 28-days all-cause mortality in patients with acute pancreatitis: a retrospective analysis of the MIMIC-IV database","volume":"13","author":"Liu","year":"2022","journal-title":"Front Immunol"},{"issue":"Pt 24","key":"10.1016\/j.ajem.2025.09.046_bb0050","doi-asserted-by":"crossref","first-page":"4561","DOI":"10.1242\/jeb.01961","article-title":"Lactate\u2013a signal coordinating cell and systemic function","volume":"208","author":"Philp","year":"2005","journal-title":"J Exp Biol"},{"key":"10.1016\/j.ajem.2025.09.046_bb0055","doi-asserted-by":"crossref","first-page":"2223","DOI":"10.1007\/s10620-024-08419-4","article-title":"Serum lactate is an indicator for short-term and long-term mortality in patients with acute pancreatitis","volume":"69","author":"Zeng","year":"2024","journal-title":"Dig Dis Sci"},{"key":"10.1016\/j.ajem.2025.09.046_bb0060","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1007\/s00134-015-4127-0","article-title":"Severe hyperlactatemia, lactate clearance and mortality in unselected critically ill patients","volume":"42","author":"Haas","year":"2016","journal-title":"Intensive Care Med"},{"issue":"1","key":"10.1016\/j.ajem.2025.09.046_bb0065","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1186\/s12951-021-00896-3","article-title":"Protein nanoparticles in drug delivery: animal protein, plant proteins and protein cages, albumin nanoparticles","volume":"19","author":"Kianfar","year":"2021","journal-title":"J Nanobiotechnol"},{"key":"10.1016\/j.ajem.2025.09.046_bb0070","doi-asserted-by":"crossref","DOI":"10.1016\/j.jclinane.2024.111632","article-title":"Association between lactate-to-albumin ratio and short-time mortality in patients with acute respiratory distress syndrome","volume":"99","author":"Wang","year":"2024","journal-title":"J Clin Anesth"},{"key":"10.1016\/j.ajem.2025.09.046_bb0075","doi-asserted-by":"crossref","DOI":"10.3389\/fcvm.2023.1233147","article-title":"The lactate to albumin ratio linked to all-cause mortality in critically ill patients with septic myocardial injury","volume":"10","author":"Chen","year":"2023","journal-title":"Front Cardiovasc Med"},{"key":"10.1016\/j.ajem.2025.09.046_bb0080","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1186\/s12879-024-08978-x","article-title":"Association between lactate-to-albumin ratio and 28-days all-cause mortality in patients with sepsis-associated liver injury: a retrospective cohort study","volume":"24","author":"Yi","year":"2024","journal-title":"BMC Infect Dis"},{"key":"10.1016\/j.ajem.2025.09.046_bb0085","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1097\/SHK.0000000000001405","article-title":"The prognostic usefulness of the lactate\/albumin ratio for predicting clinical outcomes in out-of-hospital cardiac arrest: a prospective, multicenter observational study (koCARC) study","volume":"53","author":"Kong","year":"2020","journal-title":"Shock"},{"key":"10.1016\/j.ajem.2025.09.046_bb0090","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1136\/gutjnl-2012-302779","article-title":"Classification of acute pancreatitis\u20132012: revision of the Atlanta classification and definitions by international consensus","volume":"62","author":"Banks","year":"2013","journal-title":"Gut"},{"key":"10.1016\/j.ajem.2025.09.046_bb0095","doi-asserted-by":"crossref","first-page":"974","DOI":"10.1016\/j.kint.2022.08.012","article-title":"Diabetes management in chronic kidney disease: a consensus report by the American Diabetes Association (ADA) and kidney disease: improving global outcomes (KDIGO)","volume":"102","author":"de Boer","year":"2022","journal-title":"Kidney Int"},{"key":"10.1016\/j.ajem.2025.09.046_bb0100","doi-asserted-by":"crossref","first-page":"1241","DOI":"10.1055\/a-1255-3413","article-title":"Acute kidney injury following acute pancreatitis (AP-AKI): definition, pathophysiology, diagnosis and therapy","volume":"58","author":"Scurt","year":"2020","journal-title":"Z Gastroenterol"},{"key":"10.1016\/j.ajem.2025.09.046_bb0105","doi-asserted-by":"crossref","first-page":"1179","DOI":"10.4240\/wjgs.v14.i11.1179","article-title":"Diagnosis, severity stratification and management of adult acute pancreatitis-current evidence and controversies","volume":"14","author":"Chan","year":"2022","journal-title":"World J Gastrointest Surg"},{"key":"10.1016\/j.ajem.2025.09.046_bb0110","doi-asserted-by":"crossref","first-page":"4424","DOI":"10.21037\/qims-22-158","article-title":"A new logistic regression model for early prediction of severity of acute pancreatitis using magnetic resonance imaging and acute physiology and chronic health evaluation II scoring systems","volume":"12","author":"Tang","year":"2022","journal-title":"Quant Imaging Med Surg"},{"key":"10.1016\/j.ajem.2025.09.046_bb0115","doi-asserted-by":"crossref","first-page":"2387","DOI":"10.3748\/wjg.v21.i8.2387","article-title":"Comparison of scoring systems in predicting the severity of acute pancreatitis","volume":"21","author":"Cho","year":"2015","journal-title":"World J Gastroenterol"},{"key":"10.1016\/j.ajem.2025.09.046_bb0120","doi-asserted-by":"crossref","DOI":"10.1097\/MD.0000000000009654","article-title":"Serial evaluation of the SOFA score is reliable for predicting mortality in acute severe pancreatitis","volume":"97","author":"Tee","year":"2018","journal-title":"Medicine (Baltimore)"},{"key":"10.1016\/j.ajem.2025.09.046_bb0125","article-title":"Comparing prognostic scores and inflammatory markers in predicting the severity and mortality of acute pancreatitis","volume":"15","author":"Jain","year":"2023","journal-title":"Cureus"},{"key":"10.1016\/j.ajem.2025.09.046_bb0130","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1186\/s12876-020-01268-1","article-title":"Initially elevated arterial lactate as an independent predictor of poor outcomes in severe acute pancreatitis","volume":"20","author":"Shu","year":"2020","journal-title":"BMC Gastroenterol"},{"key":"10.1016\/j.ajem.2025.09.046_bb0135","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1186\/2110-5820-3-12","article-title":"Clinical use of lactate monitoring in critically ill patients","volume":"3","author":"Bakker","year":"2013","journal-title":"Ann Intensive Care"},{"key":"10.1016\/j.ajem.2025.09.046_bb0140","doi-asserted-by":"crossref","first-page":"1127","DOI":"10.1016\/j.mayocp.2013.06.012","article-title":"Etiology and therapeutic approach to elevated lactate levels","volume":"88","author":"Andersen","year":"2013","journal-title":"Mayo Clin Proc"},{"key":"10.1016\/j.ajem.2025.09.046_bb0145","doi-asserted-by":"crossref","first-page":"2848","DOI":"10.1002\/hep.31836","article-title":"Albumin in advanced liver diseases: the good and bad of a drug!","volume":"74","author":"Jagdish","year":"2021","journal-title":"Hepatology"},{"key":"10.1016\/j.ajem.2025.09.046_bb0150","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.ejim.2009.10.010","article-title":"Serum albumin as an outcome predictor in hospital emergency medical admissions","volume":"21","author":"Lyons","year":"2010","journal-title":"Eur J Intern Med"},{"key":"10.1016\/j.ajem.2025.09.046_bb0155","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-021-03449-8","article-title":"Hypoalbuminemia affects one third of acute pancreatitis patients and is independently associated with severity and mortality","volume":"11","author":"Ocskay","year":"2021","journal-title":"Sci Rep"},{"key":"10.1016\/j.ajem.2025.09.046_bb0160","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1186\/s12876-017-0615-8","article-title":"Serum albumin, a good indicator of persistent organ failure in acute pancreatitis","volume":"17","author":"Li","year":"2017","journal-title":"BMC Gastroenterol"},{"key":"10.1016\/j.ajem.2025.09.046_bb0165","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1097\/SHK.0000000000001128","article-title":"Prognostic value of the lactate\/albumin ratio for predicting 28-day mortality in critically ILL sepsis patients","volume":"50","author":"Shin","year":"2018","journal-title":"Shock"},{"key":"10.1016\/j.ajem.2025.09.046_bb0170","doi-asserted-by":"crossref","DOI":"10.3389\/fneur.2023.1271391","article-title":"Association between lactate\/albumin ratio and 28-day all-cause mortality in ischemic stroke patients without reperfusion therapy: a retrospective analysis of the MIMIC-IV database","volume":"14","author":"Zhong","year":"2023","journal-title":"Front Neurol"},{"key":"10.1016\/j.ajem.2025.09.046_bb0175","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0255744","article-title":"Association between lactate\/albumin ratio and all-cause mortality in patients with acute respiratory failure: a retrospective analysis","volume":"16","author":"Lu","year":"2021","journal-title":"PloS One"}],"container-title":["The American Journal of Emergency Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0735675725006576?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0735675725006576?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T21:39:16Z","timestamp":1770154756000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0735675725006576"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":35,"alternative-id":["S0735675725006576"],"URL":"https:\/\/doi.org\/10.1016\/j.ajem.2025.09.046","relation":{},"ISSN":["0735-6757"],"issn-type":[{"value":"0735-6757","type":"print"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Prognostic value of the lactate-to-albumin ratio for in-hospital mortality in severe acute pancreatitis with acute kidney injury: A retrospective cohort study","name":"articletitle","label":"Article Title"},{"value":"The American Journal of Emergency Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajem.2025.09.046","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}