{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T02:46:17Z","timestamp":1790477177982,"version":"4.1.0"},"reference-count":34,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,10,6]],"date-time":"2025-10-06T00:00:00Z","timestamp":1759708800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100006447","name":"Universit\u00e4t Z\u00fcrich","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100006447","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008494","name":"Vontobel-Stiftung","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100008494","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001711","name":"Swiss National Science Foundation","doi-asserted-by":"publisher","award":["208184"],"award-info":[{"award-number":["208184"]}],"id":[{"id":"10.13039\/501100001711","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The American Journal of Emergency Medicine"],"published-print":{"date-parts":[[2026,1]]},"DOI":"10.1016\/j.ajem.2025.10.017","type":"journal-article","created":{"date-parts":[[2025,10,7]],"date-time":"2025-10-07T00:13:05Z","timestamp":1759795985000},"page":"241-247","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"special_numbering":"C","title":["Rapid diagnosis of pediatric nonconvulsive status epilepticus using point-of-care EEG"],"prefix":"10.1016","volume":"99","author":[{"given":"Leopold","family":"Simma","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katharina","family":"Moser","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michelle","family":"Seiler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"R\u00fcegger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bigna K.","family":"B\u00f6lsterli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Georgia","family":"Ramantani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.ajem.2025.10.017_bb0005","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1007\/s12245-008-0024-4","article-title":"Seizure visits in US emergency departments: epidemiology and potential disparities in care","volume":"1","author":"Pallin","year":"2008","journal-title":"Int J Emerg Med"},{"issue":"1","key":"10.1016\/j.ajem.2025.10.017_bb0010","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1097\/PEC.0000000000000682","article-title":"Epidemiology of the critically ill child in the Resuscitation Bay","volume":"34","author":"Chavez","year":"2018","journal-title":"Pediatr Emerg Care"},{"issue":"2","key":"10.1016\/j.ajem.2025.10.017_bb0015","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/j.arcped.2024.12.005","article-title":"From pediatric emergency department to pediatric intensive care unit: a retrospective study in a French tertiary university hospital","volume":"32","author":"Riche","year":"2025","journal-title":"Arch Pediatr"},{"issue":"1029","key":"10.1016\/j.ajem.2025.10.017_bb0020","article-title":"Critically ill children in a Swiss pediatric emergency department with an interdisciplinary approach: a prospective cohort study","volume":"9","author":"Simma","year":"2021","journal-title":"Front Pediatr"},{"issue":"3","key":"10.1016\/j.ajem.2025.10.017_bb0025","doi-asserted-by":"crossref","first-page":"e748","DOI":"10.1542\/peds.2011-2067","article-title":"Nonconvulsive status epilepticus: the encephalopathic pediatric patient","volume":"129","author":"Greiner","year":"2012","journal-title":"Pediatrics"},{"issue":"4","key":"10.1016\/j.ajem.2025.10.017_bb0030","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1177\/0883073813483570","article-title":"Electroencephalography in the pediatric emergency department: when is it most useful?","volume":"29","author":"Fernandez","year":"2014","journal-title":"J Child Neurol"},{"issue":"7","key":"10.1016\/j.ajem.2025.10.017_bb0035","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1586\/14737175.2014.923757","article-title":"Usefulness of video-EEG in the paediatric emergency department","volume":"14","author":"Falsaperla","year":"2014","journal-title":"Expert Rev Neurother"},{"key":"10.1016\/j.ajem.2025.10.017_bb0040","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/j.yebeh.2015.06.015","article-title":"Outcomes in pediatric patients with nonconvulsive status epilepticus","volume":"49","author":"Jafarpour","year":"2015","journal-title":"Epilepsy Behav E&B"},{"key":"10.1016\/j.ajem.2025.10.017_bb0045","series-title":"Clinical electroencephalography","first-page":"503","article-title":"Paediatric status epilepticus","author":"Specchio","year":"2019"},{"key":"10.1016\/j.ajem.2025.10.017_bb0050","article-title":"The role of electroencephalography in children with acute altered mental status of unknown etiology: a prospective study","author":"Chiarello","year":"2024","journal-title":"Neuropediatrics"},{"issue":"2","key":"10.1016\/j.ajem.2025.10.017_bb0055","doi-asserted-by":"crossref","DOI":"10.1212\/CPJ.0000000000200143","article-title":"Hospital EEG capability and associations with interhospital transfer in status epilepticus","volume":"13","author":"Suen","year":"2023","journal-title":"Neurol Clin Pract"},{"issue":"2","key":"10.1016\/j.ajem.2025.10.017_bb0060","doi-asserted-by":"crossref","DOI":"10.1212\/CPJ.0000000000200264","article-title":"The cost of after-hour electroencephalography","volume":"14","author":"Ney","year":"2024","journal-title":"Neurol Clin Pract"},{"issue":"3","key":"10.1016\/j.ajem.2025.10.017_bb0065","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1007\/s00431-025-06059-y","article-title":"Point-of-care EEG in the pediatric emergency department: a systematic review","volume":"184","author":"Simma","year":"2025","journal-title":"Eur J Pediatr"},{"issue":"7","key":"10.1016\/j.ajem.2025.10.017_bb0070","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1097\/PEC.0000000000001033","article-title":"A simplified electroencephalogram monitoring system in the emergency room","volume":"35","author":"Nozawa","year":"2019","journal-title":"Pediatr Emerg Care"},{"key":"10.1016\/j.ajem.2025.10.017_bb0075","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/j.jpeds.2018.11.019","article-title":"Nonconvulsive seizure detection by reduced-lead electroencephalography in children with altered mental status in the emergency department","volume":"207","author":"Yamaguchi","year":"2019","journal-title":"J Pediatr"},{"key":"10.1016\/j.ajem.2025.10.017_bb0080","article-title":"Feasibility and usefulness of rapid 2-channel-EEG-monitoring (point-of-care EEG) for acute CNS disorders in the paediatric emergency department: an observational study","author":"Simma","year":"2020","journal-title":"Emerg Med J"},{"issue":"9","key":"10.1016\/j.ajem.2025.10.017_bb0085","doi-asserted-by":"crossref","first-page":"e1545","DOI":"10.1097\/PEC.0000000000002811","article-title":"Benzodiazepine use for pediatric patients with suspected nonconvulsive status epilepticus with or without simplified electroencephalogram: a retrospective cohort study","volume":"38","author":"Takase","year":"2022","journal-title":"Pediatr Emerg Care"},{"key":"10.1016\/j.ajem.2025.10.017_bb0166","doi-asserted-by":"crossref","unstructured":"Simma L., Moser K., Seiler M., Ramantani G., B\u00f6lsterli BK. Implementation of point-of-care EEG in a pediatric emergency department: a quality improvement study. Eur J Pediatr. 2025;184(10):646. Published 2025 Sep 28. doi:10.1007\/s00431-025-06404-1.","DOI":"10.1007\/s00431-025-06404-1"},{"issue":"9","key":"10.1016\/j.ajem.2025.10.017_bb0090","doi-asserted-by":"crossref","DOI":"10.3390\/jpm13091411","article-title":"Integrating neuromonitoring in pediatric emergency medicine: exploring two options for point-of-care electroencephalogram (pocEEG) via patient monitors - a technical note","volume":"13","author":"Simma","year":"2023","journal-title":"J Pers Med"},{"issue":"1","key":"10.1016\/j.ajem.2025.10.017_bb0095","doi-asserted-by":"crossref","first-page":"1527","DOI":"10.1038\/s41598-018-20062-4","article-title":"Vital recorder\u2014a free research tool for automatic recording of high-resolution time-synchronised physiological data from multiple anaesthesia devices","volume":"8","author":"Lee","year":"2018","journal-title":"Sci Rep"},{"key":"10.1016\/j.ajem.2025.10.017_bb0100","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/j.pediatrneurol.2023.08.016","article-title":"Electroencephalography quality and application times in a pediatric emergency department setting: a feasibility study","volume":"148","author":"Stephens","year":"2023","journal-title":"Pediatr Neurol"},{"issue":"2","key":"10.1016\/j.ajem.2025.10.017_bb0105","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1097\/MEJ.0b013e32835473b1","article-title":"Electroencephalographic findings in consecutive emergency department patients with altered mental status: a preliminary report","volume":"20","author":"Zehtabchi","year":"2013","journal-title":"Eur J Emerg Med"},{"issue":"7","key":"10.1016\/j.ajem.2025.10.017_bb0110","doi-asserted-by":"crossref","first-page":"1739","DOI":"10.1111\/epi.17639","article-title":"Twenty-four hour pattern of childhood febrile seizures substantiated by time series meta-analysis: circadian medicine perspectives","volume":"64","author":"Smolensky","year":"2023","journal-title":"Epilepsia"},{"issue":"2","key":"10.1016\/j.ajem.2025.10.017_bb0115","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/j.jpeds.2013.09.032","article-title":"Electrographic seizures after convulsive status epilepticus in children and young adults: a retrospective multicenter study","volume":"164","author":"S\u00e1nchez Fern\u00e1ndez","year":"2014","journal-title":"J Pediatr"},{"issue":"5","key":"10.1016\/j.ajem.2025.10.017_bb0120","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1097\/WNP.0000000000000664","article-title":"EEG monitoring after convulsive status epilepticus","volume":"37","author":"Fung","year":"2020","journal-title":"J Clin Neurophysiol"},{"issue":"1","key":"10.1016\/j.ajem.2025.10.017_bb0125","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1080\/13696998.2023.2288422","article-title":"Economic review of point-of-care EEG","volume":"27","author":"Green","year":"2023","journal-title":"J Med Econ"},{"issue":"4","key":"10.1016\/j.ajem.2025.10.017_bb0130","article-title":"Point-of-care electroencephalography enables rapid evaluation and management of non-convulsive seizures and status epilepticus in the emergency department","volume":"4","author":"Kozak","year":"2023","journal-title":"J Am Coll Emerg Phys Open"},{"issue":"7","key":"10.1016\/j.ajem.2025.10.017_bb0135","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1038\/s41582-022-00664-3","article-title":"Why won\u2019t it stop? The dynamics of benzodiazepine resistance in status epilepticus","volume":"18","author":"Burman","year":"2022","journal-title":"Nat Rev Neurol"},{"key":"10.1016\/j.ajem.2025.10.017_bb0140","doi-asserted-by":"crossref","DOI":"10.1016\/j.nbd.2025.106966","article-title":"Network models incorporating chloride dynamics predict optimal strategies for terminating status epilepticus","volume":"212","author":"Currin","year":"2025","journal-title":"Neurobiol Dis"},{"key":"10.1016\/j.ajem.2025.10.017_bb0145","doi-asserted-by":"crossref","DOI":"10.1111\/epi.18398","article-title":"Synaptic inhibitory dynamics drive benzodiazepine response in pediatric status epilepticus","author":"Fedele","year":"2025","journal-title":"Epilepsia"},{"key":"10.1016\/j.ajem.2025.10.017_bb0150","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/j.resuscitation.2018.12.022","article-title":"Preliminary experience with point-of-care EEG in post-cardiac arrest patients","volume":"135","author":"Rittenberger","year":"2019","journal-title":"Resuscitation"},{"issue":"8","key":"10.1016\/j.ajem.2025.10.017_bb0155","doi-asserted-by":"crossref","first-page":"1214","DOI":"10.1007\/s12630-021-01962-y","article-title":"Educational initiatives for electroencephalography in the critical care setting: a systematic review and meta-analysis","volume":"68","author":"Taran","year":"2021","journal-title":"Can J Anaesth"},{"issue":"1","key":"10.1016\/j.ajem.2025.10.017_bb0160","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1186\/s12245-019-0228-9","article-title":"Improving the ability of ED physicians to identify subclinical\/electrographic seizures on EEG after a brief training module","volume":"12","author":"Chari","year":"2019","journal-title":"Int J Emerg Med"},{"key":"10.1016\/j.ajem.2025.10.017_bb0165","doi-asserted-by":"crossref","DOI":"10.2196\/69395","article-title":"E-learning for pediatric emergency department staff in point-of-care electroencephalogram interpretation: a prospective cohort study","volume":"11","author":"Simma","year":"2025","journal-title":"JMIR Med Educ"}],"container-title":["The American Journal of Emergency Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0735675725006783?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0735675725006783?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T13:42:18Z","timestamp":1773150138000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0735675725006783"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":34,"alternative-id":["S0735675725006783"],"URL":"https:\/\/doi.org\/10.1016\/j.ajem.2025.10.017","relation":{},"ISSN":["0735-6757"],"issn-type":[{"value":"0735-6757","type":"print"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Rapid diagnosis of pediatric nonconvulsive status epilepticus using point-of-care EEG","name":"articletitle","label":"Article Title"},{"value":"The American Journal of Emergency Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajem.2025.10.017","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}