{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T00:04:27Z","timestamp":1780445067970,"version":"3.54.1"},"reference-count":23,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100002655","name":"Beckman Coulter Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100002655","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The American Journal of Emergency Medicine"],"published-print":{"date-parts":[[2026,8]]},"DOI":"10.1016\/j.ajem.2026.05.005","type":"journal-article","created":{"date-parts":[[2026,5,6]],"date-time":"2026-05-06T15:23:28Z","timestamp":1778081008000},"page":"102-106","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Is an ED discharge safe after a single cardiac troponin: Analysis of the FAST-TRAC study"],"prefix":"10.1016","volume":"106","author":[{"given":"W. Frank","family":"Peacock","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Mueller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefan D.","family":"Anker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fred S.","family":"Apple","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert H.","family":"Christenson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lori B.","family":"Daniels","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deborah B.","family":"Diercks","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Salvatore","family":"Di Somma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerasimos","family":"Filippatos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gary","family":"Headden","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian","family":"Hiestand","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Judd E.","family":"Hollander","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joshua M.","family":"Kosowsky","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gary M.","family":"Vilke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Than","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey","family":"Budd","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ajem.2026.05.005_bb0005","first-page":"1","article-title":"National Hospital Ambulatory Medical Care Survey: 2005 emergency department summary","volume":"386","author":"Nawar","year":"2007","journal-title":"Adv Data"},{"key":"10.1016\/j.ajem.2026.05.005_bb0010","doi-asserted-by":"crossref","first-page":"752","DOI":"10.1016\/j.ijcard.2012.09.171","article-title":"What is an acceptable risk of major adverse cardiac event in chest pain patients soon after discharge from the emergency department?: a clinical survey","volume":"166","author":"Than","year":"2013","journal-title":"Int J Cardiol"},{"issue":"13","key":"10.1016\/j.ajem.2026.05.005_bb0015","first-page":"e771","article-title":"2025 ACC\/AHA\/ACEP\/NAEMSP\/SCAI guideline for the Management of Patients with Acute Coronary Syndromes: a report of the American College of Cardiology\/American Heart Association Joint Committee on clinical practice guidelines","volume":"151","author":"Rao","year":"2025","journal-title":"Circulation"},{"issue":"1","key":"10.1016\/j.ajem.2026.05.005_bb0020","doi-asserted-by":"crossref","first-page":"101","DOI":"10.7326\/M21-1499","article-title":"Performance of the European Society of Cardiology 0\/1-hour, 0\/2-hour, and 0\/3-hour algorithms for rapid triage of acute myocardial infarction\u202f: an international collaborative meta-analysis","volume":"175","author":"Chiang","year":"2022","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.ajem.2026.05.005_bb0025","doi-asserted-by":"crossref","DOI":"10.1136\/bmj.d2983","article-title":"Association between waiting times and short-term mortality and hospital admission after departure from emergency department: population based cohort study from Ontario, Canada","volume":"342","author":"Guttmann","year":"2011","journal-title":"BMJ"},{"issue":"7","key":"10.1016\/j.ajem.2026.05.005_bb0030","article-title":"Rapid rule-out of acute myocardial infarction with a single high-sensitivity cardiac Troponin T measurement below the limit of detection: a collaborative meta-analysis. Ann Intern Med. 2017 166(10):715-724. Doi:10.7326\/M16-2562. Epub 2017 Apr 18","volume":"167","author":"Pickering","year":"2017","journal-title":"Err Ann intern med"},{"issue":"2","key":"10.1016\/j.ajem.2026.05.005_bb0035","doi-asserted-by":"crossref","first-page":"140","DOI":"10.15441\/ceem.21.154","article-title":"Finding acute coronary syndrome with serial troponin testing for rapid assessment of cardiac ischemic symptoms (FAST-TRAC): a study protocol","volume":"9","author":"Peacock","year":"2022","journal-title":"Clin Exp Emerg Med"},{"key":"10.1016\/j.ajem.2026.05.005_bb0040","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2016-012799","article-title":"STARD 2015 guidelines for reporting diagnostic accuracy studies: explanation and elaboration","volume":"6","author":"Cohen","year":"2016","journal-title":"BMJ Open"},{"key":"10.1016\/j.ajem.2026.05.005_bb0045","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.clinbiochem.2020.05.014","article-title":"Analytical and clinical characterization of a novel high-sensitivity cardiac troponin assay in a United States population","volume":"83","author":"Christenson","year":"2020","journal-title":"Clin Biochem"},{"issue":"20","key":"10.1016\/j.ajem.2026.05.005_bb0050","doi-asserted-by":"crossref","first-page":"1498","DOI":"10.1136\/heartjnl-2012-302188","article-title":"Cost-effectiveness of presentation versus delayed troponin testing for acute myocardial infarction","volume":"98","author":"Thokala","year":"2012","journal-title":"Heart"},{"issue":"18","key":"10.1016\/j.ajem.2026.05.005_bb0055","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1136\/heartjnl-2024-325188","article-title":"Single high-sensitivity troponin levels to assess patients with potential acute coronary syndromes: 1-year outcomes","volume":"111","author":"Barnes","year":"2025","journal-title":"Heart"},{"issue":"9","key":"10.1016\/j.ajem.2026.05.005_bb0060","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1136\/emermed-2024-214754","article-title":"Improving care with the first measurement of high-sensitivity troponin T (ICare-FirsT) to enable early rule out and reduce length of stay: a diagnostic and observational study","volume":"42","author":"Pickering","year":"2025","journal-title":"Emerg Med J"},{"issue":"1","key":"10.1016\/j.ajem.2026.05.005_bb0065","doi-asserted-by":"crossref","DOI":"10.21542\/gcsp.2025.8","article-title":"Utilization and outcomes of single-troponin discharge from the emergency department in a low-risk population","volume":"2025","author":"Zhou","year":"2025","journal-title":"Global Cardiology Science and Practice"},{"issue":"10","key":"10.1016\/j.ajem.2026.05.005_bb0070","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.124.039379","article-title":"Comparative analysis of single- and dual-marker strategies for rapid Non-ST-Segment-Elevation myocardial infarction rule-out using cardiac Myosin-Binding Protein C, Copeptin, and high-sensitivity cardiac Troponin T in the emergency department","volume":"14","author":"Yildirim","year":"2025","journal-title":"J Am Heart Assoc"},{"issue":"7","key":"10.1016\/j.ajem.2026.05.005_bb0075","first-page":"412","article-title":"Zero-hour thresholds to risk stratify patients for acute myocardial infarction using a point-of-care high-sensitivity troponin assay","volume":"14","author":"Greenslade","year":"2025","journal-title":"Eur Heart J Acute Cardiovasc Care"},{"issue":"8","key":"10.1016\/j.ajem.2026.05.005_bb0080","doi-asserted-by":"crossref","first-page":"1643","DOI":"10.1515\/cclm-2024-1387","article-title":"Novel Mindray high sensitivity cardiac troponin I assay for single sample and 0\/2-hour rule out of myocardial infarction: MERITnI study","volume":"63","author":"Buda","year":"2025","journal-title":"Clin Chem Lab Med"},{"issue":"6","key":"10.1016\/j.ajem.2026.05.005_bb0085","doi-asserted-by":"crossref","DOI":"10.1093\/ehjopen\/oeae094","article-title":"Single high-sensitivity troponin-I for ruling out acute coronary syndrome: a detection limit approach","volume":"4","author":"Hickling","year":"2024","journal-title":"Eur Heart J Open"},{"issue":"11","key":"10.1016\/j.ajem.2026.05.005_bb0090","article-title":"Lot-to-lot variation for commercial high-sensitivity cardiac troponin: can we realistically report down to the assay\u2019s limit of detection? Clin Chem. 2020 Sep 1;66(9):1146\u20131149. doi:10.1093\/clinchem\/hvaa160","volume":"66","author":"Wu","year":"2020","journal-title":"Err Clin Chem"},{"issue":"6","key":"10.1016\/j.ajem.2026.05.005_bb0095","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1093\/clinchem\/hvad033","article-title":"Rapid rule-out of myocardial infarction using a single high-sensitivity cardiac troponin I measurement strategy at presentation to the emergency department: the SAFETY study","volume":"69","author":"Fabre-Estremera","year":"2023","journal-title":"Clin Chem"},{"issue":"1","key":"10.1016\/j.ajem.2026.05.005_bb0100","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1093\/clinchem\/hvaa280","article-title":"Optimizing the use of high-sensitivity troponin assays for the early rule-out of myocardial infarction in patients presenting with chest pain: a systematic review","volume":"67","author":"Westwood","year":"2021","journal-title":"Clin Chem"},{"issue":"3","key":"10.1016\/j.ajem.2026.05.005_bb0105","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/j.jacc.2019.05.058","article-title":"Myocardial infarction risk stratification with a single measurement of high-sensitivity troponin I","volume":"74","author":"Sandoval","year":"2019","journal-title":"J Am Coll Cardiol"},{"issue":"11","key":"10.1016\/j.ajem.2026.05.005_bb0110","doi-asserted-by":"crossref","first-page":"808","DOI":"10.1136\/emermed-2020-210833","article-title":"Diagnostic accuracy of the HEART pathway and EDACS-ADP when combined with a 0-hour\/1-hour hs-cTnT protocol for assessment of acute chest pain patients","volume":"38","author":"Nilsson","year":"2021","journal-title":"Emerg Med J"},{"issue":"6","key":"10.1016\/j.ajem.2026.05.005_bb0115","article-title":"Outcomes in ED patients with non-specific ECG findings and low high-sensitivity troponin","volume":"3","author":"Alshaikh","year":"2022","journal-title":"J Am Coll Emerg Physicians Open"}],"container-title":["The American Journal of Emergency Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0735675726002111?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0735675726002111?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T23:03:37Z","timestamp":1780441417000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0735675726002111"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8]]},"references-count":23,"alternative-id":["S0735675726002111"],"URL":"https:\/\/doi.org\/10.1016\/j.ajem.2026.05.005","relation":{},"ISSN":["0735-6757"],"issn-type":[{"value":"0735-6757","type":"print"}],"subject":[],"published":{"date-parts":[[2026,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Is an ED discharge safe after a single cardiac troponin: Analysis of the FAST-TRAC study","name":"articletitle","label":"Article Title"},{"value":"The American Journal of Emergency Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajem.2026.05.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}