{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T20:48:15Z","timestamp":1792097295389,"version":"4.4.0"},"reference-count":31,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The American Journal of Emergency Medicine"],"published-print":{"date-parts":[[2026,12]]},"DOI":"10.1016\/j.ajem.2026.09.057","type":"journal-article","created":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T23:48:55Z","timestamp":1791503335000},"page":"604-611","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Emergency medicine updates: Contrast media hypersensitivity"],"prefix":"10.1016","volume":"110","author":[{"given":"Isaac J.","family":"Kim","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jim","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brit","family":"Long","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hans","family":"Rosenberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.ajem.2026.09.057_bb0005","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1177\/08465371241311253","article-title":"CAR\/CSACI practice guidance for contrast media hypersensitivity","volume":"76","author":"Byrne","year":"2025","journal-title":"Can Assoc Radiol J"},{"issue":"6","key":"10.1016\/j.ajem.2026.09.057_bb0010","doi-asserted-by":"crossref","first-page":"710","DOI":"10.1001\/jamainternmed.2025.0505","article-title":"Projected lifetime cancer risks from current computed tomography imaging","volume":"185","author":"Smith-Bindman","year":"2025","journal-title":"JAMA Intern Med"},{"issue":"9","key":"10.1016\/j.ajem.2026.09.057_bb0015","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1097\/RLI.0000000000000696","article-title":"Developments in X-ray contrast media and the potential impact on computed tomography","volume":"55","author":"Sch\u00f6ckel","year":"2020","journal-title":"Invest Radiol"},{"key":"10.1016\/j.ajem.2026.09.057_bb0020","author":"American College of Radiology"},{"key":"10.1016\/j.ajem.2026.09.057_bb0025","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.ajem.2022.08.052","article-title":"Impact of iodinated contrast allergies on emergency department operations","volume":"61","author":"Berlyand","year":"2022","journal-title":"Am J Emerg Med"},{"issue":"2","key":"10.1016\/j.ajem.2026.09.057_bb0030","doi-asserted-by":"crossref","DOI":"10.1148\/radiol.240100","article-title":"Management and prevention of hypersensitivity reactions to radiocontrast media: a consensus statement from the American College of Radiology and the American Academy of Allergy, Asthma & Immunology","volume":"315","author":"Wang","year":"2025","journal-title":"Radiology"},{"issue":"3","key":"10.1016\/j.ajem.2026.09.057_bb0035","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/0091-6749(81)90059-2","article-title":"Pretreatment of high-risk patients requiring radiographic contrast media studies","volume":"67","author":"Greenberger","year":"1981","journal-title":"J Allergy Clin Immunol"},{"issue":"14","key":"10.1016\/j.ajem.2026.09.057_bb0040","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1056\/NEJM198710013171401","article-title":"Pretreatment with corticosteroids to alleviate reactions to intravenous contrast material","volume":"317","author":"Lasser","year":"1987","journal-title":"N Engl J Med"},{"issue":"3","key":"10.1016\/j.ajem.2026.09.057_bb0045","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1148\/radiology.175.3.2343107","article-title":"Adverse reactions to ionic and nonionic contrast media. A report from the Japanese committee on the safety of contrast media","volume":"175","author":"Katayama","year":"1990","journal-title":"Radiology"},{"issue":"2","key":"10.1016\/j.ajem.2026.09.057_bb0050","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1148\/radiol.210545","article-title":"Allergic-like hypersensitivity reactions to gadolinium-based contrast agents: an 8-year cohort study of 154 539 patients","volume":"303","author":"Ahn","year":"2022","journal-title":"Radiology"},{"issue":"11","key":"10.1016\/j.ajem.2026.09.057_bb0055","doi-asserted-by":"crossref","first-page":"6811","DOI":"10.1007\/s00330-025-11676-0","article-title":"Hypersensitivity reactions to contrast media: part 2. Prevention of recurrent hypersensitivity reactions in adults. Updated guidelines by the ESUR contrast media safety committee","volume":"35","author":"Van Der Molen","year":"2025","journal-title":"Eur Radiol"},{"issue":"11","key":"10.1016\/j.ajem.2026.09.057_bb0060","doi-asserted-by":"crossref","first-page":"6798","DOI":"10.1007\/s00330-025-11675-1","article-title":"Hypersensitivity reactions to contrast media: part 1. Management of immediate and non-immediate hypersensitivity reactions in adults. Updated guidelines by the ESUR contrast media safety committee","volume":"35","author":"Van Der Molen","year":"2025","journal-title":"Eur Radiol"},{"issue":"7","key":"10.1016\/j.ajem.2026.09.057_bb0065","doi-asserted-by":"crossref","first-page":"2205","DOI":"10.1016\/j.jaip.2019.02.035","article-title":"Differences in adverse reactions among iodinated contrast media: analysis of the KAERS database","volume":"7","author":"An","year":"2019","journal-title":"J Allergy Clin Immunol Pract"},{"issue":"12","key":"10.1016\/j.ajem.2026.09.057_bb0070","doi-asserted-by":"crossref","first-page":"1820","DOI":"10.1016\/j.mayocp.2023.02.032","article-title":"Acute adverse events after iodinated contrast agent administration of 359,977 injections: a single-center retrospective study","volume":"98","author":"McDonald","year":"2023","journal-title":"Mayo Clin Proc"},{"issue":"5","key":"10.1016\/j.ajem.2026.09.057_bb0075","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1016\/j.jemermed.2009.10.014","article-title":"The relationship of radiocontrast, iodine, and seafood allergies: a medical myth exposed","volume":"39","author":"Schabelman","year":"2010","journal-title":"J Emerg Med"},{"issue":"2","key":"10.1016\/j.ajem.2026.09.057_bb0080","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/j.anai.2023.09.015","article-title":"Anaphylaxis: a 2023 practice parameter update","volume":"132","author":"Golden","year":"2024","journal-title":"Ann Allergy Asthma Immunol"},{"issue":"6","key":"10.1016\/j.ajem.2026.09.057_bb0085","doi-asserted-by":"crossref","first-page":"1342","DOI":"10.1016\/j.jaip.2025.04.008","article-title":"Diagnostic utility of biomarkers in anaphylaxis: a systematic review and meta-analysis","volume":"13","author":"Khalaf","year":"2025","journal-title":"J Allergy Clin Immunol Pract"},{"issue":"8","key":"10.1016\/j.ajem.2026.09.057_bb0090","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.1016\/j.jacr.2019.01.027","article-title":"Quality of documentation of contrast agent allergies in electronic health records","volume":"16","author":"Deng","year":"2019","journal-title":"J Am Coll Radiol"},{"issue":"1","key":"10.1016\/j.ajem.2026.09.057_bb0095","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1148\/radiol.2021210490","article-title":"Prevention of allergic-like reactions at repeat CT: steroid pretreatment versus contrast material substitution","volume":"301","author":"McDonald","year":"2021","journal-title":"Radiology"},{"key":"10.1016\/j.ajem.2026.09.057_bb0100","doi-asserted-by":"crossref","DOI":"10.1177\/08465371251401551","article-title":"CAR\/CSACI practice guidance for contrast media hypersensitivity: update for unknown contrast agents","author":"Byrne","year":"2026","journal-title":"Can Assoc Radiol J"},{"issue":"1","key":"10.1016\/j.ajem.2026.09.057_bb0105","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1148\/radiol.2019190485","article-title":"Hypersensitivity reactions to iodinated contrast media: a multicenter study of 196 081 patients","volume":"293","author":"Cha","year":"2019","journal-title":"Radiology"},{"issue":"3","key":"10.1016\/j.ajem.2026.09.057_bb0110","doi-asserted-by":"crossref","first-page":"710","DOI":"10.1148\/radiol.2018172524","article-title":"Immediate mild reactions to CT with iodinated contrast media: strategy of contrast media Readministration without corticosteroids","volume":"288","author":"Park","year":"2018","journal-title":"Radiology"},{"issue":"3","key":"10.1016\/j.ajem.2026.09.057_bb0115","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/j.anai.2016.11.027","article-title":"Stratified premedication strategy for the prevention of contrast media hypersensitivity in high-risk patients","volume":"118","author":"Lee","year":"2017","journal-title":"Ann Allergy Asthma Immunol"},{"issue":"7","key":"10.1016\/j.ajem.2026.09.057_bb0120","first-page":"2052","article-title":"By the 2023 American Geriatrics Society Beers Criteria\u00ae Update Expert Panel. American Geriatrics Society 2023 updated AGS Beers Criteria\u00ae for potentially inappropriate medication use in older adults","volume":"71","year":"2023","journal-title":"J Am Geriatr Soc"},{"issue":"2","key":"10.1016\/j.ajem.2026.09.057_bb0125","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1148\/radiol.2017170107","article-title":"Intravenous corticosteroid premedication administered 5 hours before CT compared with a traditional 13-hour Oral regimen","volume":"285","author":"Mervak","year":"2017","journal-title":"Radiology"},{"issue":"1","key":"10.1016\/j.ajem.2026.09.057_bb0130","doi-asserted-by":"crossref","first-page":"77","DOI":"10.2214\/AJR.14.13810","article-title":"Rates of breakthrough reactions in inpatients at high risk receiving premedication before contrast-enhanced CT","volume":"205","author":"Mervak","year":"2015","journal-title":"Am J Roentgenol"},{"key":"10.1016\/j.ajem.2026.09.057_bb0135","article-title":"Short term use of oral corticosteroids and related harms among adults in the United States: population based cohort study","volume":"357","author":"Waljee","year":"2017","journal-title":"BMJ"},{"issue":"2","key":"10.1016\/j.ajem.2026.09.057_bb0140","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1148\/radiol.2015151143","article-title":"Indirect cost and harm attributable to oral 13-hour inpatient corticosteroid prophylaxis before contrast-enhanced CT","volume":"279","author":"Davenport","year":"2016","journal-title":"Radiology"},{"issue":"2","key":"10.1016\/j.ajem.2026.09.057_bb0145","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1148\/radiol.220370","article-title":"Iodinated contrast media substitution to prevent recurrent hypersensitivity reactions: a systematic review and meta-analysis","volume":"305","author":"Umakoshi","year":"2022","journal-title":"Radiology"},{"issue":"1","key":"10.1016\/j.ajem.2026.09.057_bb0150","doi-asserted-by":"crossref","DOI":"10.1148\/radiol.222467","article-title":"Substitution with low-osmolar iodinated contrast agent to minimize recurrent immediate hypersensitivity reaction","volume":"309","author":"Kim","year":"2023","journal-title":"Radiology"},{"issue":"10","key":"10.1016\/j.ajem.2026.09.057_bb0155","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1097\/RLI.0000000000000573","article-title":"Preventive effect of changing contrast media in patients with a Prior Mild Immediate Hypersensitivity Reaction to gadolinium-based contrast agent","volume":"54","author":"Ryoo","year":"2019","journal-title":"Invest Radiol"}],"container-title":["The American Journal of Emergency Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0735675726005218?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0735675726005218?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T20:40:44Z","timestamp":1792096844000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0735675726005218"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,12]]},"references-count":31,"alternative-id":["S0735675726005218"],"URL":"https:\/\/doi.org\/10.1016\/j.ajem.2026.09.057","relation":{},"ISSN":["0735-6757"],"issn-type":[{"value":"0735-6757","type":"print"}],"subject":[],"published":{"date-parts":[[2026,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Emergency medicine updates: Contrast media hypersensitivity","name":"articletitle","label":"Article Title"},{"value":"The American Journal of Emergency Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajem.2026.09.057","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}