{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T19:30:51Z","timestamp":1780342251192,"version":"3.54.1"},"reference-count":8,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Arab Journal of Gastroenterology"],"published-print":{"date-parts":[[2022,11]]},"DOI":"10.1016\/j.ajg.2022.06.008","type":"journal-article","created":{"date-parts":[[2022,10,10]],"date-time":"2022-10-10T14:08:58Z","timestamp":1665410938000},"page":"288-289","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"title":["Hypersplenism and thrombocytopenia after exposure to ustekinumab in a patient with Crohn\u2019s disease"],"prefix":"10.1016","volume":"23","author":[{"given":"Mansour A.","family":"Altuwaijri","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maha J.","family":"Aljasser","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"46","key":"10.1016\/j.ajg.2022.06.008_b0005","doi-asserted-by":"crossref","first-page":"7227","DOI":"10.3748\/wjg.v11.i46.7227","article-title":"Extraintestinal manifestations in inflammatory bowel disease","volume":"11","author":"Danese","year":"2005","journal-title":"World J Gastroenterol"},{"issue":"10","key":"10.1016\/j.ajg.2022.06.008_b0010","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1038\/nrgastro.2013.117","article-title":"Extraintestinal manifestations and complications in IBD","volume":"10","author":"Ott","year":"2013","journal-title":"Nat Rev Gastroenterol Hepatol"},{"issue":"1","key":"10.1016\/j.ajg.2022.06.008_b0015","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1146\/annurev.med.51.1.289","article-title":"Role of cytokines in the pathogenesis of inflammatory bowel disease","volume":"51","author":"Papadakis","year":"2000","journal-title":"Annu Rev Med"},{"issue":"20","key":"10.1016\/j.ajg.2022.06.008_b0020","doi-asserted-by":"crossref","first-page":"1946","DOI":"10.1056\/NEJMoa1602773","article-title":"Ustekinumab as induction and maintenance therapy for Crohn's disease","volume":"375","author":"Feagan","year":"2016","journal-title":"N Engl J Med"},{"issue":"7","key":"10.1016\/j.ajg.2022.06.008_b0025","doi-asserted-by":"crossref","first-page":"994","DOI":"10.1093\/ibd\/izaa236","article-title":"Safety of ustekinumab in inflammatory bowel disease: pooled safety analysis of results from phase 2\/3 studies","volume":"27","author":"Sandborn","year":"2021","journal-title":"Inflam Bowel Dis"},{"issue":"1","key":"10.1016\/j.ajg.2022.06.008_b0030","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1111\/j.1749-6632.2011.05963.x","article-title":"Development of the IL-12\/23 antagonist ustekinumab in psoriasis: Past, present, and future perspectives","volume":"1222","author":"Yeilding","year":"2011","journal-title":"Ann N Y Acad Sci"},{"issue":"3","key":"10.1016\/j.ajg.2022.06.008_b0035","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1097\/md.0b013e18064f9f3","article-title":"Aseptic abscesses: A study of 30 patients with or without inflammatory bowel disease and review of the literature","volume":"86","author":"Andr\u00e9","year":"2007","journal-title":"Medicine (Baltimore)"},{"key":"10.1016\/j.ajg.2022.06.008_b0040","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2020\/4785759","article-title":"Immune thrombocytopenic purpura (ITP) as an uncommon extraintestinal complication of Crohn's disease: Case vignette and systematic literature review","volume":"2020","author":"Epistola","year":"2020","journal-title":"Case Rep Hematol"}],"updated-by":[{"DOI":"10.1016\/j.ajg.2023.06.001","type":"erratum","label":"Erratum","source":"publisher","updated":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000}}],"container-title":["Arab Journal of Gastroenterology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1687197922000594?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1687197922000594?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,12,6]],"date-time":"2022-12-06T19:20:06Z","timestamp":1670354406000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1687197922000594"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,11]]},"references-count":8,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2022,11]]}},"alternative-id":["S1687197922000594"],"URL":"https:\/\/doi.org\/10.1016\/j.ajg.2022.06.008","relation":{},"ISSN":["1687-1979"],"issn-type":[{"value":"1687-1979","type":"print"}],"subject":[],"published":{"date-parts":[[2022,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Hypersplenism and thrombocytopenia after exposure to ustekinumab in a patient with Crohn\u2019s disease","name":"articletitle","label":"Article Title"},{"value":"Arab Journal of Gastroenterology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajg.2022.06.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"simple-article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Pan-Arab Association of Gastroenterology. Published by Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}