{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,9]],"date-time":"2026-11-09T04:26:42Z","timestamp":1794198402790,"version":"4.8.0"},"reference-count":58,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,1,7]],"date-time":"2022-01-07T00:00:00Z","timestamp":1641513600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["T32-HL007227"],"award-info":[{"award-number":["T32-HL007227"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000057","name":"National Institute of General Medical Sciences","doi-asserted-by":"publisher","award":["R01GM120167"],"award-info":[{"award-number":["R01GM120167"]}],"id":[{"id":"10.13039\/100000057","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000057","name":"National Institute of General Medical Sciences","doi-asserted-by":"publisher","award":["R35GM139580"],"award-info":[{"award-number":["R35GM139580"]}],"id":[{"id":"10.13039\/100000057","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The American Journal of Human Genetics"],"published-print":{"date-parts":[[2022,2]]},"DOI":"10.1016\/j.ajhg.2022.01.002","type":"journal-article","created":{"date-parts":[[2022,1,31]],"date-time":"2022-01-31T05:26:11Z","timestamp":1643606771000},"page":"223-239","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":93,"title":["Redefining tissue specificity of genetic regulation of gene expression in the presence of allelic heterogeneity"],"prefix":"10.1016","volume":"109","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8046-6123","authenticated-orcid":false,"given":"Marios","family":"Arvanitis","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karl","family":"Tayeb","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin J.","family":"Strober","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5287-627X","authenticated-orcid":false,"given":"Alexis","family":"Battle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ajhg.2022.01.002_bib1","doi-asserted-by":"crossref","first-page":"1122","DOI":"10.1038\/s41467-020-14843-7","article-title":"Genome-wide association and multi-omic analyses reveal ACTN2 as a gene linked to heart failure","volume":"11","author":"Arvanitis","year":"2020","journal-title":"Nat. Commun."},{"key":"10.1016\/j.ajhg.2022.01.002_bib2","doi-asserted-by":"crossref","first-page":"e1008538","DOI":"10.1371\/journal.pgen.1008538","article-title":"Genomic profiling of human vascular cells identifies TWIST1 as a causal gene for common vascular diseases","volume":"16","author":"Nurnberg","year":"2020","journal-title":"PLoS Genet."},{"key":"10.1016\/j.ajhg.2022.01.002_bib3","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1186\/s13059-021-02334-x","article-title":"The impact of cell type and context-dependent regulatory variants on human immune traits","volume":"22","author":"Mu","year":"2021","journal-title":"Genome Biol."},{"key":"10.1016\/j.ajhg.2022.01.002_bib4","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1038\/s41588-020-0625-2","article-title":"Quantifying genetic effects on disease mediated by assayed gene expression levels","volume":"52","author":"Yao","year":"2020","journal-title":"Nat. Genet."},{"key":"10.1016\/j.ajhg.2022.01.002_bib5","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1038\/ng.3795","article-title":"Limited statistical evidence for shared genetic effects of eQTLs and autoimmune-disease-associated loci in three major immune-cell types","volume":"49","author":"Chun","year":"2017","journal-title":"Nat. Genet."},{"key":"10.1016\/j.ajhg.2022.01.002_bib6","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1038\/nature24277","article-title":"Genetic effects on gene expression across human tissues","volume":"550","author":"Battle","year":"2017","journal-title":"Nature"},{"key":"10.1016\/j.ajhg.2022.01.002_bib7","doi-asserted-by":"crossref","first-page":"1896","DOI":"10.1016\/j.bbadis.2014.04.024","article-title":"From genome to function by studying eQTLs","volume":"1842","author":"Westra","year":"2014","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.ajhg.2022.01.002_bib8","article-title":"CCmed: cross-condition mediation analysis for identifying robust trans-eQTLs and assessing their effects on human traits","author":"Yang","year":"2019","journal-title":"bioRxiv"},{"key":"10.1016\/j.ajhg.2022.01.002_bib9","article-title":"Multiple Causal Variants Underlie Genetic Associations in Humans","author":"Abell","year":"2021","journal-title":"bioRxiv"},{"key":"10.1016\/j.ajhg.2022.01.002_bib10","doi-asserted-by":"crossref","first-page":"1318","DOI":"10.1126\/science.aaz1776","article-title":"The GTEx Consortium atlas of genetic regulatory effects across human tissues","volume":"369","year":"2020","journal-title":"Science"},{"key":"10.1016\/j.ajhg.2022.01.002_bib11","doi-asserted-by":"crossref","first-page":"e1003491","DOI":"10.1371\/journal.pgen.1003491","article-title":"Effectively identifying eQTLs from multiple tissues by combining mixed model and meta-analytic approaches","volume":"9","author":"Sul","year":"2013","journal-title":"PLoS Genet."},{"key":"10.1016\/j.ajhg.2022.01.002_bib12","doi-asserted-by":"crossref","first-page":"e1004383","DOI":"10.1371\/journal.pgen.1004383","article-title":"Bayesian test for colocalisation between pairs of genetic association studies using summary statistics","volume":"10","author":"Giambartolomei","year":"2014","journal-title":"PLoS Genet."},{"key":"10.1016\/j.ajhg.2022.01.002_bib13","doi-asserted-by":"crossref","first-page":"1245","DOI":"10.1016\/j.ajhg.2016.10.003","article-title":"Colocalization of GWAS and eQTL Signals Detects Target Genes","volume":"99","author":"Hormozdiari","year":"2016","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.ajhg.2022.01.002_bib14","doi-asserted-by":"crossref","first-page":"1084","DOI":"10.1038\/ng.2394","article-title":"Mapping cis- and trans-regulatory effects across multiple tissues in twins","volume":"44","author":"Grundberg","year":"2012","journal-title":"Nat. Genet."},{"key":"10.1016\/j.ajhg.2022.01.002_bib15","doi-asserted-by":"crossref","first-page":"1300","DOI":"10.1038\/s41588-021-00913-z","article-title":"Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression","volume":"53","author":"V\u00f5sa","year":"2021","journal-title":"Nat. Genet."},{"key":"10.1016\/j.ajhg.2022.01.002_bib16","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1038\/nmeth.3337","article-title":"Robust enumeration of cell subsets from tissue expression profiles","volume":"12","author":"Newman","year":"2015","journal-title":"Nat. Methods"},{"key":"10.1016\/j.ajhg.2022.01.002_bib17","doi-asserted-by":"crossref","first-page":"955","DOI":"10.1038\/s41467-020-14561-0","article-title":"Cellular deconvolution of GTEx tissues powers discovery of disease and cell-type associated regulatory variants","volume":"11","author":"Donovan","year":"2020","journal-title":"Nat. Commun."},{"key":"10.1016\/j.ajhg.2022.01.002_bib18","doi-asserted-by":"crossref","first-page":"1353","DOI":"10.1093\/bioinformatics\/bts163","article-title":"Matrix eQTL: ultra fast eQTL analysis via large matrix operations","volume":"28","author":"Shabalin","year":"2012","journal-title":"Bioinformatics"},{"key":"10.1016\/j.ajhg.2022.01.002_bib19","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1038\/ng.3211","article-title":"LD Score regression distinguishes confounding from polygenicity in genome-wide association studies","volume":"47","author":"Bulik-Sullivan","year":"2015","journal-title":"Nat. Genet."},{"key":"10.1016\/j.ajhg.2022.01.002_bib20","doi-asserted-by":"crossref","first-page":"1561","DOI":"10.1214\/17-AOAS1046","article-title":"Bayesian Large-Scale Multiple Regression with Summary Statistics from Genome-Wide Association Studies","volume":"11","author":"Zhu","year":"2017","journal-title":"Ann. Appl. Stat."},{"key":"10.1016\/j.ajhg.2022.01.002_bib21","article-title":"Variational Inference: A Review for Statisticians","author":"Blei","year":"2017","journal-title":"arXiv"},{"key":"10.1016\/j.ajhg.2022.01.002_bib22","doi-asserted-by":"crossref","first-page":"2478","DOI":"10.1038\/nprot.2017.124","article-title":"Chromatin-state discovery and\u00a0genome annotation with ChromHMM","volume":"12","author":"Ernst","year":"2017","journal-title":"Nat. Protoc."},{"issue":"D1","key":"10.1016\/j.ajhg.2022.01.002_bib23","doi-asserted-by":"crossref","first-page":"D325","DOI":"10.1093\/nar\/gkaa1113","article-title":"The Gene Ontology resource: enriching a GOld mine","volume":"49","year":"2021","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.ajhg.2022.01.002_bib24","doi-asserted-by":"crossref","first-page":"15545","DOI":"10.1073\/pnas.0506580102","article-title":"Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles","volume":"102","author":"Subramanian","year":"2005","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.ajhg.2022.01.002_bib25","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1038\/s41586-020-2308-7","article-title":"The mutational constraint spectrum quantified from variation in 141,456 humans","volume":"581","author":"Karczewski","year":"2020","journal-title":"Nature"},{"key":"10.1016\/j.ajhg.2022.01.002_bib26","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1038\/nature19057","article-title":"Analysis of protein-coding genetic variation in 60,706 humans","volume":"536","author":"Lek","year":"2016","journal-title":"Nature"},{"key":"10.1016\/j.ajhg.2022.01.002_bib27","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1038\/s41586-018-0579-z","article-title":"The UK Biobank resource with deep phenotyping and genomic data","volume":"562","author":"Bycroft","year":"2018","journal-title":"Nature"},{"key":"10.1016\/j.ajhg.2022.01.002_bib28","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1161\/CIRCRESAHA.117.312086","article-title":"Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease","volume":"122","author":"van der Harst","year":"2018","journal-title":"Circ. Res."},{"key":"10.1016\/j.ajhg.2022.01.002_bib29","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1038\/s41588-018-0081-4","article-title":"Heritability enrichment of specifically expressed genes identifies disease-relevant tissues and cell types","volume":"50","author":"Finucane","year":"2018","journal-title":"Nat. Genet."},{"key":"10.1016\/j.ajhg.2022.01.002_bib30","doi-asserted-by":"crossref","first-page":"3481","DOI":"10.1161\/CIRCULATIONAHA.105.537878","article-title":"Pathophysiology of coronary artery disease","volume":"111","author":"Libby","year":"2005","journal-title":"Circulation"},{"key":"10.1016\/j.ajhg.2022.01.002_bib31","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.atherosclerosis.2019.02.012","article-title":"Regulation of MFGE8 by the intergenic coronary artery disease locus on 15q26.1","volume":"284","author":"Soubeyrand","year":"2019","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.ajhg.2022.01.002_bib32","doi-asserted-by":"crossref","first-page":"1202","DOI":"10.1161\/CIRCULATIONAHA.114.012669","article-title":"Knockout of Adamts7, a novel coronary artery disease locus in humans, reduces atherosclerosis in mice","volume":"131","author":"Bauer","year":"2015","journal-title":"Circulation"},{"key":"10.1016\/j.ajhg.2022.01.002_bib33","doi-asserted-by":"crossref","first-page":"972","DOI":"10.1161\/ATVBAHA.116.307294","article-title":"Functional Analysis of a Novel Genome-Wide Association Study Signal in SMAD3 That Confers Protection From Coronary Artery Disease","volume":"36","author":"Turner","year":"2016","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"10.1016\/j.ajhg.2022.01.002_bib34","doi-asserted-by":"crossref","first-page":"e1006127","DOI":"10.1371\/journal.pgen.1006127","article-title":"Coronary-Heart-Disease-Associated Genetic Variant at the COL4A1\/COL4A2 Locus Affects COL4A1\/COL4A2 Expression, Vascular Cell Survival, Atherosclerotic Plaque Stability and Risk of Myocardial Infarction","volume":"12","author":"Yang","year":"2016","journal-title":"PLoS Genet."},{"key":"10.1016\/j.ajhg.2022.01.002_bib35","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1172\/JCI88899","article-title":"Blood pressure-associated polymorphism controls ARHGAP42 expression via serum response factor DNA binding","volume":"127","author":"Bai","year":"2017","journal-title":"J.\u00a0Clin. Invest."},{"key":"10.1016\/j.ajhg.2022.01.002_bib36","doi-asserted-by":"crossref","first-page":"1796","DOI":"10.1016\/j.cell.2018.11.014","article-title":"Unveiling the Role of the Most Impactful Cardiovascular Risk Locus through Haplotype Editing","volume":"175","author":"Lo Sardo","year":"2018","journal-title":"Cell"},{"key":"10.1016\/j.ajhg.2022.01.002_bib37","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1016\/j.cell.2017.06.049","article-title":"A Genetic Variant Associated with Five Vascular Diseases Is a Distal Regulator of Endothelin-1 Gene Expression","volume":"170","author":"Gupta","year":"2017","journal-title":"Cell"},{"key":"10.1016\/j.ajhg.2022.01.002_bib38","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1186\/s13059-019-1749-5","article-title":"Integrative analysis of vascular endothelial cell genomic features identifies AIDA as a coronary artery disease candidate gene","volume":"20","author":"Lalonde","year":"2019","journal-title":"Genome Biol."},{"key":"10.1016\/j.ajhg.2022.01.002_bib39","doi-asserted-by":"crossref","first-page":"e1007755","DOI":"10.1371\/journal.pgen.1007755","article-title":"Functional regulatory mechanism of smooth muscle cell-restricted LMOD1 coronary artery disease locus","volume":"14","author":"Nanda","year":"2018","journal-title":"PLoS Genet."},{"key":"10.1016\/j.ajhg.2022.01.002_bib40","doi-asserted-by":"crossref","first-page":"714","DOI":"10.1038\/nature09266","article-title":"From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus","volume":"466","author":"Musunuru","year":"2010","journal-title":"Nature"},{"key":"10.1016\/j.ajhg.2022.01.002_bib41","doi-asserted-by":"crossref","first-page":"E11349","DOI":"10.1073\/pnas.1810568115","article-title":"Genetic variant at coronary artery disease and ischemic stroke locus 1p32.2 regulates endothelial responses to hemodynamics","volume":"115","author":"Krause","year":"2018","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.ajhg.2022.01.002_bib42","doi-asserted-by":"crossref","first-page":"956","DOI":"10.1038\/s41588-018-0154-4","article-title":"Using an atlas of gene regulation across 44 human tissues to inform complex disease- and trait-associated variation","volume":"50","author":"Gamazon","year":"2018","journal-title":"Nat. Genet."},{"key":"10.1016\/j.ajhg.2022.01.002_bib43","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1186\/s13059-020-02113-0","article-title":"Impact of admixture and ancestry on eQTL analysis and GWAS colocalization in GTEx","volume":"21","author":"Gay","year":"2020","journal-title":"Genome Biol."},{"key":"10.1016\/j.ajhg.2022.01.002_bib44","series-title":"Mendelian Inheritance in Man: A Catalog of Human Genes and Genetic Disorders","author":"McKusick","year":"1998"},{"key":"10.1016\/j.ajhg.2022.01.002_bib45","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1038\/nrg.2016.160","article-title":"Genetics of coronary artery disease: discovery, biology and clinical translation","volume":"18","author":"Khera","year":"2017","journal-title":"Nat. Rev. Genet."},{"key":"10.1016\/j.ajhg.2022.01.002_bib46","doi-asserted-by":"crossref","first-page":"5141","DOI":"10.1038\/s41467-018-07340-5","article-title":"GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes","volume":"9","author":"Franceschini","year":"2018","journal-title":"Nat. Commun."},{"key":"10.1016\/j.ajhg.2022.01.002_bib47","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1534\/genetics.114.167908","article-title":"Identifying causal variants at loci with multiple signals of association","volume":"198","author":"Hormozdiari","year":"2014","journal-title":"Genetics"},{"key":"10.1016\/j.ajhg.2022.01.002_bib48","doi-asserted-by":"crossref","first-page":"764","DOI":"10.1038\/s41467-020-20885-8","article-title":"A fast and efficient colocalization algorithm for identifying shared genetic risk factors across multiple traits","volume":"12","author":"Foley","year":"2021","journal-title":"Nat. Commun."},{"key":"10.1016\/j.ajhg.2022.01.002_bib49","doi-asserted-by":"crossref","first-page":"e1007778","DOI":"10.1371\/journal.pcbi.1007778","article-title":"A powerful and versatile colocalization test","volume":"16","author":"Deng","year":"2020","journal-title":"PLoS Comput. Biol."},{"key":"10.1016\/j.ajhg.2022.01.002_bib50","doi-asserted-by":"crossref","first-page":"1825","DOI":"10.1038\/s41467-018-03621-1","article-title":"Exploring the phenotypic consequences of tissue specific gene expression variation inferred from GWAS summary statistics","volume":"9","author":"Barbeira","year":"2018","journal-title":"Nat. Commun."},{"key":"10.1016\/j.ajhg.2022.01.002_bib51","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1186\/s12863-019-0786-0","article-title":"SNP eQTL status and eQTL density in the adjacent region of the SNP are associated with its statistical significance in GWA studies","volume":"20","author":"Gorlov","year":"2019","journal-title":"BMC Genet."},{"key":"10.1016\/j.ajhg.2022.01.002_bib52","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1186\/s13059-020-02129-6","article-title":"sn-spMF: matrix factorization informs tissue-specific genetic regulation of gene expression","volume":"21","author":"He","year":"2020","journal-title":"Genome Biol."},{"key":"10.1016\/j.ajhg.2022.01.002_bib53","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1186\/s12859-021-04170-z","article-title":"Estimating colocalization probability from limited summary statistics","volume":"22","author":"King","year":"2021","journal-title":"BMC Bioinformatics"},{"key":"10.1016\/j.ajhg.2022.01.002_bib54","doi-asserted-by":"crossref","first-page":"e1008915","DOI":"10.1371\/journal.pcbi.1008915","article-title":"Leveraging eQTLs to identify individual-level tissue of interest for a complex trait","volume":"17","author":"Majumdar","year":"2021","journal-title":"PLoS Comput. Biol."},{"key":"10.1016\/j.ajhg.2022.01.002_bib55","doi-asserted-by":"crossref","first-page":"1676","DOI":"10.1038\/ng.3981","article-title":"Estimating the causal tissues for complex traits and diseases","volume":"49","author":"Ongen","year":"2017","journal-title":"Nat. Genet."},{"key":"10.1016\/j.ajhg.2022.01.002_bib56","doi-asserted-by":"crossref","first-page":"6283","DOI":"10.1038\/s41467-020-20188-y","article-title":"Functional studies of GWAS variants are gaining momentum","volume":"11","author":"Lichou","year":"2020","journal-title":"Nat. Commun."},{"key":"10.1016\/j.ajhg.2022.01.002_bib57","doi-asserted-by":"crossref","first-page":"1246949","DOI":"10.1126\/science.1246949","article-title":"Innate immune activity conditions the effect of regulatory variants upon monocyte gene expression","volume":"343","author":"Fairfax","year":"2014","journal-title":"Science"},{"key":"10.1016\/j.ajhg.2022.01.002_bib58","doi-asserted-by":"crossref","first-page":"1287","DOI":"10.1126\/science.aaw0040","article-title":"Dynamic genetic regulation of gene expression during cellular differentiation","volume":"364","author":"Strober","year":"2019","journal-title":"Science"}],"container-title":["The American Journal of Human Genetics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002929722000027?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002929722000027?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T07:22:49Z","timestamp":1757575369000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002929722000027"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,2]]},"references-count":58,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2022,2]]}},"alternative-id":["S0002929722000027"],"URL":"https:\/\/doi.org\/10.1016\/j.ajhg.2022.01.002","relation":{"has-preprint":[{"id-type":"doi","id":"10.1101\/2021.06.28.21259545","asserted-by":"object"}]},"ISSN":["0002-9297"],"issn-type":[{"value":"0002-9297","type":"print"}],"subject":[],"published":{"date-parts":[[2022,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Redefining tissue specificity of genetic regulation of gene expression in the presence of allelic heterogeneity","name":"articletitle","label":"Article Title"},{"value":"The American Journal of Human Genetics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajhg.2022.01.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 The Authors.","name":"copyright","label":"Copyright"}]}}