{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T09:15:44Z","timestamp":1781774144021,"version":"3.54.5"},"reference-count":58,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,1,29]],"date-time":"2025-01-29T00:00:00Z","timestamp":1738108800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000054","name":"National Institutes of Health National Cancer Institute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002794","name":"Swedish Cancer Society","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002794","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The American Journal of Human Genetics"],"published-print":{"date-parts":[[2025,3]]},"DOI":"10.1016\/j.ajhg.2025.01.022","type":"journal-article","created":{"date-parts":[[2025,2,24]],"date-time":"2025-02-24T16:07:37Z","timestamp":1740413257000},"page":"630-643","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"title":["Identification of genes associated with testicular germ cell tumor susceptibility through a transcriptome-wide association study"],"prefix":"10.1016","volume":"112","author":[{"given":"Emilio","family":"Ugalde-Morales","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rona","family":"Wilf","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Pluta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Ploner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mengyao","family":"Fan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad","family":"Damra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katja K.","family":"Aben","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lynn","family":"Anson-Cartwright","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chu","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victoria K.","family":"Cortessis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siamak","family":"Daneshmand","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alberto","family":"Ferlin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marija","family":"Gamulin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jourik A.","family":"Gietema","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Gonzalez-Niera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tom","family":"Grotmol","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert J.","family":"Hamilton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark","family":"Harland","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Trine B.","family":"Haugen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Russ","family":"Hauser","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michelle A.T.","family":"Hildebrandt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Karlsson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lambertus A.","family":"Kiemeney","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jung","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Davor","family":"Lessel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ragnhild A.","family":"Lothe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chey","family":"Loveday","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen J.","family":"Chanock","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katherine A.","family":"McGlynn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Coby","family":"Meijer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin T.","family":"Nead","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeremie","family":"Nsengimana","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maja","family":"Popovic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thorunn","family":"Rafnar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lorenzo","family":"Richiardi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria S.","family":"Rocca","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen M.","family":"Schwartz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rolf I.","family":"Skotheim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kari","family":"Stefansson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Douglas R.","family":"Stewart","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clare","family":"Turnbull","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David J.","family":"Vaughn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sofia B.","family":"Winge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tongzhang","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alvaro N.","family":"Monteiro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristian","family":"Almstrup","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter A.","family":"Kanetsky","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katherine L.","family":"Nathanson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4623-0544","authenticated-orcid":false,"given":"Fredrik","family":"Wiklund","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ajhg.2025.01.022_bib1","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.eururo.2016.02.029","article-title":"The 2016 WHO Classification of Tumours of the Urinary System and Male Genital Organs-Part A: Renal, Penile, and Testicular Tumours","volume":"70","author":"Moch","year":"2016","journal-title":"Eur. Urol."},{"key":"10.1016\/j.ajhg.2025.01.022_bib2","doi-asserted-by":"crossref","first-page":"209","DOI":"10.3322\/caac.21660","article-title":"Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries","volume":"71","author":"Sung","year":"2021","journal-title":"CA. Cancer J. Clin."},{"key":"10.1016\/j.ajhg.2025.01.022_bib3","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1016\/j.eururo.2019.07.002","article-title":"International Trends in the Incidence of Testicular Cancer: Lessons from 35 Years and 41 Countries","volume":"76","author":"Gurney","year":"2019","journal-title":"Eur. Urol."},{"key":"10.1016\/j.ajhg.2025.01.022_bib4","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1375\/twin.8.5.509","article-title":"Are twins at risk of cancer: results from the Swedish family-cancer database","volume":"8","author":"Hemminki","year":"2005","journal-title":"Twin Res. Hum. Genet."},{"key":"10.1016\/j.ajhg.2025.01.022_bib5","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1002\/ijc.10441","article-title":"Cancer risks in twins: results from the Swedish family-cancer database","volume":"99","author":"Hemminki","year":"2002","journal-title":"Int. J. Cancer"},{"key":"10.1016\/j.ajhg.2025.01.022_bib6","doi-asserted-by":"crossref","first-page":"1765","DOI":"10.1038\/sj.bjc.6601714","article-title":"Familial risk in testicular cancer as a clue to a heritable and environmental aetiology","volume":"90","author":"Hemminki","year":"2004","journal-title":"Br. J. Cancer"},{"key":"10.1016\/j.ajhg.2025.01.022_bib7","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1038\/sj.bjc.6604136","article-title":"Testicular cancer in twins: a meta-analysis","volume":"98","author":"Neale","year":"2008","journal-title":"Br. J. Cancer"},{"key":"10.1016\/j.ajhg.2025.01.022_bib8","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1054\/bjoc.2000.1585","article-title":"Sibling risks in cancer: clues to recessive or X-linked genes?","volume":"84","author":"Hemminki","year":"2001","journal-title":"Br. J. Cancer"},{"key":"10.1016\/j.ajhg.2025.01.022_bib9","doi-asserted-by":"crossref","first-page":"5241","DOI":"10.1158\/0008-5472.CAN-08-4554","article-title":"Analysis of gene expression profiles of microdissected cell populations indicates that testicular carcinoma in\u00a0situ is an arrested gonocyte","volume":"69","author":"Sonne","year":"2009","journal-title":"Cancer Res."},{"key":"10.1016\/j.ajhg.2025.01.022_bib10","doi-asserted-by":"crossref","first-page":"1713","DOI":"10.1007\/s00018-019-03022-7","article-title":"Testicular germ cell tumor: a comprehensive review","volume":"76","author":"Batool","year":"2019","journal-title":"Cell. Mol. Life Sci."},{"key":"10.1016\/j.ajhg.2025.01.022_bib11","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1038\/nrurol.2016.107","article-title":"The genomic landscape of testicular germ cell tumours: from susceptibility to treatment","volume":"13","author":"Litchfield","year":"2016","journal-title":"Nat. Rev. Urol."},{"key":"10.1016\/j.ajhg.2025.01.022_bib12","series-title":"Smith\u00a0& Tanagho's General Urology, 19e","article-title":"Genital Tumors","author":"Porten","year":"2020"},{"key":"10.1016\/j.ajhg.2025.01.022_bib13","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/j.ajhg.2017.06.005","article-title":"10 Years of GWAS Discovery: Biology, Function, and Translation","volume":"101","author":"Visscher","year":"2017","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.ajhg.2025.01.022_bib14","doi-asserted-by":"crossref","first-page":"4487","DOI":"10.1038\/s41467-021-24334-y","article-title":"Identification of 22 susceptibility loci associated with testicular germ cell tumors","volume":"12","author":"Pluta","year":"2021","journal-title":"Nat. Commun."},{"key":"10.1016\/j.ajhg.2025.01.022_bib15","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1038\/ng.2634","article-title":"Meta-analysis identifies four new loci associated with testicular germ cell tumor","volume":"45","author":"Chung","year":"2013","journal-title":"Nat. Genet."},{"key":"10.1016\/j.ajhg.2025.01.022_bib16","doi-asserted-by":"crossref","first-page":"3109","DOI":"10.1093\/hmg\/ddr207","article-title":"A second independent locus within DMRT1 is associated with testicular germ cell tumor susceptibility","volume":"20","author":"Kanetsky","year":"2011","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.ajhg.2025.01.022_bib17","doi-asserted-by":"crossref","first-page":"4138","DOI":"10.1093\/hmg\/ddv129","article-title":"Two new loci and gene sets related to sex determination and cancer progression are associated with susceptibility to testicular germ cell tumor","volume":"24","author":"Kristiansen","year":"2015","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.ajhg.2025.01.022_bib18","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1038\/ng.2635","article-title":"Identification of nine new susceptibility loci for testicular cancer, including variants near DAZL and PRDM14","volume":"45","author":"Ruark","year":"2013","journal-title":"Nat. Genet."},{"key":"10.1016\/j.ajhg.2025.01.022_bib19","doi-asserted-by":"crossref","first-page":"2748","DOI":"10.1093\/hmg\/ddt109","article-title":"Testicular germ cell tumor susceptibility associated with the UCK2 locus on chromosome 1q23","volume":"22","author":"Schumacher","year":"2013","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.ajhg.2025.01.022_bib20","doi-asserted-by":"crossref","first-page":"1141","DOI":"10.1038\/ng.3879","article-title":"Meta-analysis of five genome-wide association studies identifies multiple new loci associated with testicular germ cell tumor","volume":"49","author":"Wang","year":"2017","journal-title":"Nat. Genet."},{"key":"10.1016\/j.ajhg.2025.01.022_bib21","doi-asserted-by":"crossref","first-page":"1091","DOI":"10.1038\/ng.3367","article-title":"A gene-based association method for mapping traits using reference transcriptome data","volume":"47","author":"Gamazon","year":"2015","journal-title":"Nat. Genet."},{"key":"10.1016\/j.ajhg.2025.01.022_bib22","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1038\/s42003-023-05279-y","article-title":"Transcriptome-wide association studies: recent advances in methods, applications and available databases","volume":"6","author":"Mai","year":"2023","journal-title":"Commun. Biol."},{"key":"10.1016\/j.ajhg.2025.01.022_bib23","doi-asserted-by":"crossref","first-page":"1318","DOI":"10.1126\/science.aaz1776","article-title":"The GTEx Consortium atlas of genetic regulatory effects across human tissues","volume":"369","year":"2020","journal-title":"Science"},{"key":"10.1016\/j.ajhg.2025.01.022_bib24","doi-asserted-by":"crossref","first-page":"1113","DOI":"10.1038\/ng.2764","article-title":"The Cancer Genome Atlas Pan-Cancer analysis project","volume":"45","author":"Weinstein","year":"2013","journal-title":"Nat. Genet."},{"key":"10.1016\/j.ajhg.2025.01.022_bib25","doi-asserted-by":"crossref","first-page":"3392","DOI":"10.1016\/j.celrep.2018.05.039","article-title":"Integrated Molecular Characterization of Testicular Germ Cell Tumors","volume":"23","author":"Shen","year":"2018","journal-title":"Cell Rep."},{"key":"10.1016\/j.ajhg.2025.01.022_bib26","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pgen.1008973","article-title":"Leveraging expression from multiple tissues using sparse canonical correlation analysis and aggregate tests improves the power of transcriptome-wide association studies","volume":"17","author":"Feng","year":"2021","journal-title":"PLoS Genet."},{"key":"10.1016\/j.ajhg.2025.01.022_bib27","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1038\/ng.3506","article-title":"Integrative approaches for large-scale transcriptome-wide association studies","volume":"48","author":"Gusev","year":"2016","journal-title":"Nat. Genet."},{"key":"10.1016\/j.ajhg.2025.01.022_bib28","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1038\/nature15393","article-title":"A global reference for human genetic variation","volume":"526","author":"Auton","year":"2015","journal-title":"Nature"},{"key":"10.1016\/j.ajhg.2025.01.022_bib29","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pgen.1004383","article-title":"Bayesian Test for Colocalisation between Pairs of Genetic Association Studies Using Summary Statistics","volume":"10","author":"Giambartolomei","year":"2014","journal-title":"PLoS Genet."},{"key":"10.1016\/j.ajhg.2025.01.022_bib30","doi-asserted-by":"crossref","first-page":"4079","DOI":"10.1038\/s41467-018-06302-1","article-title":"Large-scale transcriptome-wide association study identifies new prostate cancer risk regions","volume":"9","author":"Mancuso","year":"2018","journal-title":"Nat. Commun."},{"key":"10.1016\/j.ajhg.2025.01.022_bib31","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1038\/s41586-022-04918-4","article-title":"Single-cell roadmap of human gonadal development","volume":"607","author":"Garcia-Alonso","year":"2022","journal-title":"Nature"},{"key":"10.1016\/j.ajhg.2025.01.022_bib32","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1387\/ijdb.082668ss","article-title":"Analysis of SOX2 expression in developing human testis and germ cell neoplasia","volume":"54","author":"Sonne","year":"2010","journal-title":"Int. J. Dev. Biol."},{"key":"10.1016\/j.ajhg.2025.01.022_bib33","doi-asserted-by":"crossref","first-page":"858","DOI":"10.3389\/fgene.2019.00858","article-title":"pathfindR: An R Package for Comprehensive Identification of Enriched Pathways in Omics Data Through Active Subnetworks","volume":"10","author":"Ulgen","year":"2019","journal-title":"Front. Genet."},{"key":"10.1016\/j.ajhg.2025.01.022_bib34","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pcbi.1005968","article-title":"Reactome graph database: Efficient access to complex pathway data","volume":"14","author":"Fabregat","year":"2018","journal-title":"PLoS Comput. Biol."},{"key":"10.1016\/j.ajhg.2025.01.022_bib35","doi-asserted-by":"crossref","first-page":"D687","DOI":"10.1093\/nar\/gkab1028","article-title":"The reactome pathway knowledgebase 2022","volume":"50","author":"Gillespie","year":"2022","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.ajhg.2025.01.022_bib36","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1002\/pro.3978","article-title":"The BioGRID database: A comprehensive biomedical resource of curated protein, genetic, and chemical interactions","volume":"30","author":"Oughtred","year":"2021","journal-title":"Protein Sci."},{"key":"10.1016\/j.ajhg.2025.01.022_bib37","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-019-49177-y","article-title":"Characterisation and localisation of the endocannabinoid system components in the adult human testis","volume":"9","author":"Nielsen","year":"2019","journal-title":"Sci. Rep."},{"key":"10.1016\/j.ajhg.2025.01.022_bib38","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1038\/ng.607","article-title":"Variants near DMRT1, TERT and ATF7IP are associated with testicular germ cell cancer","volume":"42","author":"Turnbull","year":"2010","journal-title":"Nat. Genet."},{"key":"10.1016\/j.ajhg.2025.01.022_bib39","doi-asserted-by":"crossref","first-page":"5165","DOI":"10.1074\/jbc.M807098200","article-title":"MCAF1\/AM is involved in Sp1-mediated maintenance of cancer-associated telomerase activity","volume":"284","author":"Liu","year":"2009","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.ajhg.2025.01.022_bib40","doi-asserted-by":"crossref","first-page":"25271","DOI":"10.18632\/aging.203745","article-title":"An integrative pan-cancer analysis reveals the oncogenic role of mutS homolog 6 (MSH6) in human tumors","volume":"13","author":"Zhan","year":"2021","journal-title":"Aging (Albany NY)"},{"key":"10.1016\/j.ajhg.2025.01.022_bib41","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1007\/s10815-007-9167-0","article-title":"Expression profile of genes coding for DNA repair in human oocytes using pangenomic microarrays, with a special focus on ROS linked decays","volume":"24","author":"Menezo","year":"2007","journal-title":"J.\u00a0Assist. Reprod. Genet."},{"key":"10.1016\/j.ajhg.2025.01.022_bib42","doi-asserted-by":"crossref","DOI":"10.1038\/ncomms14755","article-title":"Comprehensive population-wide analysis of Lynch syndrome in Iceland reveals founder mutations in MSH6 and PMS2","volume":"8","author":"Haraldsdottir","year":"2017","journal-title":"Nat. Commun."},{"key":"10.1016\/j.ajhg.2025.01.022_bib43","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1186\/s13072-022-00462-7","article-title":"The mismatch-repair proteins MSH2 and MSH6 interact with the imprinting control regions through the ZFP57-KAP1 complex","volume":"15","author":"Acurzio","year":"2022","journal-title":"Epigenet. Chromatin"},{"key":"10.1016\/j.ajhg.2025.01.022_bib44","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1038\/s41572-018-0029-0","article-title":"Testicular cancer","volume":"4","author":"Cheng","year":"2018","journal-title":"Nat. Rev. Dis. Primers"},{"key":"10.1016\/j.ajhg.2025.01.022_bib45","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1038\/nrc1568","article-title":"Testicular germ-cell tumours in a broader perspective","volume":"5","author":"Oosterhuis","year":"2005","journal-title":"Nat. Rev. Cancer"},{"key":"10.1016\/j.ajhg.2025.01.022_bib46","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1038\/s41568-019-0178-9","article-title":"Human germ cell tumours from a developmental perspective","volume":"19","author":"Oosterhuis","year":"2019","journal-title":"Nat. Rev. Cancer"},{"key":"10.1016\/j.ajhg.2025.01.022_bib47","doi-asserted-by":"crossref","DOI":"10.1016\/j.gene.2020.144458","article-title":"ARID3A and ARID3B induce stem promoting pathways in ovarian cancer cells","volume":"738","author":"Dausinas","year":"2020","journal-title":"Gene"},{"key":"10.1016\/j.ajhg.2025.01.022_bib48","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0131961","article-title":"ARID3B Directly Regulates Ovarian Cancer Promoting Genes","volume":"10","author":"Bobbs","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.ajhg.2025.01.022_bib49","doi-asserted-by":"crossref","first-page":"8355","DOI":"10.18632\/oncotarget.2247","article-title":"ARID3B increases ovarian tumor burden and is associated with a cancer stem cell gene\u00a0signature","volume":"5","author":"Roy","year":"2014","journal-title":"Oncotarget"},{"key":"10.1016\/j.ajhg.2025.01.022_bib50","doi-asserted-by":"crossref","first-page":"2553","DOI":"10.1158\/0008-5472.CAN-14-2215","article-title":"Lin28B\/Let-7 Regulates Expression of Oct4 and Sox2 and Reprograms Oral Squamous Cell Carcinoma Cells to a Stem-like State","volume":"75","author":"Chien","year":"2015","journal-title":"Cancer Res."},{"key":"10.1016\/j.ajhg.2025.01.022_bib51","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1038\/nature05284","article-title":"A protein interaction network for pluripotency of embryonic stem cells","volume":"444","author":"Wang","year":"2006","journal-title":"Nature"},{"key":"10.1016\/j.ajhg.2025.01.022_bib52","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.ydbio.2005.12.016","article-title":"Microarray analysis of PDGFR alpha+ populations in ES cell differentiation culture identifies genes involved in differentiation of mesoderm and mesenchyme including ARID3b that is essential for development of embryonic mesenchymal cells","volume":"293","author":"Takebe","year":"2006","journal-title":"Dev. Biol."},{"key":"10.1016\/j.ajhg.2025.01.022_bib53","doi-asserted-by":"crossref","first-page":"2640","DOI":"10.1038\/onc.2012.285","article-title":"Epigenetic regulation of the neuroblastoma genes, Arid3b and Mycn","volume":"32","author":"Kobayashi","year":"2013","journal-title":"Oncogene"},{"key":"10.1016\/j.ajhg.2025.01.022_bib54","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1093\/carcin\/bgh283","article-title":"Apoptosis in the development and treatment of cancer","volume":"26","author":"Gerl","year":"2005","journal-title":"Carcinogenesis"},{"key":"10.1016\/j.ajhg.2025.01.022_bib55","doi-asserted-by":"crossref","first-page":"3244","DOI":"10.18632\/oncotarget.27696","article-title":"Urinary glycoproteomic profiling of non-muscle invasive and muscle invasive bladder carcinoma patients reveals distinct N-glycosylation pattern of CD44, MGAM, and GINM1","volume":"11","author":"Sathe","year":"2020","journal-title":"Oncotarget"},{"key":"10.1016\/j.ajhg.2025.01.022_bib56","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1038\/ng.393","article-title":"Common variation in KITLG and at 5q31.3 predisposes to testicular germ cell cancer","volume":"41","author":"Kanetsky","year":"2009","journal-title":"Nat. Genet."},{"key":"10.1016\/j.ajhg.2025.01.022_bib57","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1016\/j.eururo.2023.05.008","article-title":"Germline Exome Sequencing for Men with Testicular Germ Cell Tumor Reveals Coding Defects in Chromosomal Segregation and Protein-targeting Genes","volume":"85","author":"Pyle","year":"2024","journal-title":"Eur. Urol."},{"key":"10.1016\/j.ajhg.2025.01.022_bib58","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1126\/science.aad9417","article-title":"RNA splicing is a primary link between genetic variation and disease","volume":"352","author":"Li","year":"2016","journal-title":"Science"}],"container-title":["The American Journal of Human Genetics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002929725000229?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002929725000229?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,4,11]],"date-time":"2025-04-11T03:15:50Z","timestamp":1744341350000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002929725000229"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3]]},"references-count":58,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2025,3]]}},"alternative-id":["S0002929725000229"],"URL":"https:\/\/doi.org\/10.1016\/j.ajhg.2025.01.022","relation":{},"ISSN":["0002-9297"],"issn-type":[{"value":"0002-9297","type":"print"}],"subject":[],"published":{"date-parts":[[2025,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Identification of genes associated with testicular germ cell tumor susceptibility through a transcriptome-wide association study","name":"articletitle","label":"Article Title"},{"value":"The American Journal of Human Genetics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajhg.2025.01.022","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Author(s). Published by Elsevier Inc. on behalf of American Society of Human Genetics.","name":"copyright","label":"Copyright"}]}}