{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,8]],"date-time":"2026-04-08T16:28:18Z","timestamp":1775665698745,"version":"3.50.1"},"reference-count":19,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["ajicjournal.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["American Journal of Infection Control"],"published-print":{"date-parts":[[2021,10]]},"DOI":"10.1016\/j.ajic.2021.07.012","type":"journal-article","created":{"date-parts":[[2021,7,25]],"date-time":"2021-07-25T09:25:08Z","timestamp":1627205108000},"page":"1227-1231","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":21,"title":["Vapourized hydrogen peroxide decontamination in a hospital setting inactivates SARS-CoV-2 and HCoV-229E without compromising filtration efficiency of unexpired N95 respirators"],"prefix":"10.1016","volume":"49","author":[{"given":"Natasha","family":"Christie-Holmes","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rachel","family":"Tyli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrick","family":"Budylowski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Furkan","family":"Guvenc","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amit","family":"Weiner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Betty","family":"Poon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mary","family":"Speck","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephenie","family":"Naugler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Allen","family":"Rainville","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ayoob","family":"Ghalami","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shannon","family":"McCaw","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steven","family":"Hayes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samira","family":"Mubareka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Scott D.","family":"Gray-Owen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ori D.","family":"Rotstein","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rita A.","family":"Kandel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James A.","family":"Scott","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ajic.2021.07.012_bib0001","unstructured":"US Centers for Disease Control and Prevention [Internet], Atlanta: interim guidance on infection control measures for 2009 H1N1 influenza in healthcare settings, including protection of healthcare personnel; 2009. Available at: https:\/\/www.cdc.gov\/h1n1flu\/guidelines_infection_control.htm. Accessed August 24, 2021."},{"key":"10.1016\/j.ajic.2021.07.012_bib0002","unstructured":"World Health Organization [Internet], Geneva: Infection prevention and control of epidemic- and pandemic-prone acute respiratory infections in healthcare, 2014. Available at: https:\/\/www.who.int\/publications\/i\/item\/infection-prevention-and-control-of-epidemic-and-pandemic-prone-acute-respiratory-infections-in-health-care. Accessed August 24, 2021."},{"key":"10.1016\/j.ajic.2021.07.012_bib0003","unstructured":"Campbell A., The SARS commission. [Internet] Toronto; 2007. Available at: http:\/\/www.archives.gov.on.ca\/en\/e_records\/sars\/index.html. Accessed August 24, 2021."},{"key":"10.1016\/j.ajic.2021.07.012_bib0004","first-page":"815","article-title":"Evaluation of five decontamination methods for filtering facepiece respirators","volume":"53","author":"Viscusi","year":"2009","journal-title":"Ann Occup Hyg"},{"key":"10.1016\/j.ajic.2021.07.012_bib0005","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1016\/j.ajic.2010.07.004","article-title":"A pandemic influenza preparedness study: use of energetic methods to decontaminate filtering facepiece respirators contaminated with H1N1 aerosols and droplets","volume":"39","author":"Heimbuch","year":"2011","journal-title":"Am J Infect Control"},{"key":"10.1016\/j.ajic.2021.07.012_bib0006","doi-asserted-by":"crossref","first-page":"1520","DOI":"10.1016\/j.ajic.2020.07.004","article-title":"Decontamination and reuse of N95 filtering facemask respirators: a systematic review of the literature","volume":"48","author":"Rodriguez-Martinez","year":"2020","journal-title":"Am J Infect Control"},{"key":"10.1016\/j.ajic.2021.07.012_bib0007","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/j.jhin.2014.02.003","article-title":"Evaluating the virucidal efficacy of hydrogen peroxide vapour","volume":"86","author":"Goyal","year":"2014","journal-title":"J Hosp Infect"},{"key":"10.1016\/j.ajic.2021.07.012_bib0008","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1016\/j.jhin.2020.01.022","article-title":"Persistence of coronaviruses on inanimate surfaces and their inactivation with biocidal agents","volume":"104","author":"Kampf","year":"2020","journal-title":"J Hosp Infect"},{"key":"10.1016\/j.ajic.2021.07.012_bib0009","doi-asserted-by":"crossref","first-page":"2253","DOI":"10.3201\/eid2609.201524","article-title":"Effectiveness of N95 respirator decontamination and reuse against SARS-CoV-2 virus","volume":"26","author":"Fischer","year":"2020","journal-title":"Emerg Infect Dis"},{"key":"10.1016\/j.ajic.2021.07.012_bib0010","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0243965","article-title":"Decontamination of N95 masks for re-use employing 7 widely available sterilization methods","volume":"15","author":"Kumar","year":"2020","journal-title":"PLoS One"},{"key":"10.1016\/j.ajic.2021.07.012_bib0011","doi-asserted-by":"crossref","first-page":"2054","DOI":"10.3201\/eid2609.201495","article-title":"Isolation, sequence, infectivity, and replication kinetics of severe acute respiratory syndrome coronavirus 2","volume":"26","author":"Banerjee","year":"2020","journal-title":"Emerg Infect Dis"},{"key":"10.1016\/j.ajic.2021.07.012_bib0012","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/S0166-0934(03)00192-7","article-title":"A disc-based quantitative carrier test method to assess the virucidal activity of chemical germicides","volume":"112","author":"Sattar","year":"2003","journal-title":"J Virol Methods"},{"key":"10.1016\/j.ajic.2021.07.012_bib0013","doi-asserted-by":"crossref","first-page":"714","DOI":"10.1021\/es60130a004","article-title":"Trimmed Spearman\u2013Karber method for estimating median lethal concentrations in toxicity bioassays","volume":"11","author":"Hamilton","year":"1977","journal-title":"Environ Sci Technol"},{"key":"10.1016\/j.ajic.2021.07.012_bib0014","first-page":"227","article-title":"The method of \u2018right and wrong cases\u2019 (\u2018constant stimuli\u2019) without Gauss's formulae","volume":"2","author":"Spearman","year":"1908","journal-title":"Br J Psychol"},{"key":"10.1016\/j.ajic.2021.07.012_bib0015","series-title":"Fluid filtration: Gas, Volume I, ASTM STP 975","first-page":"p.2986","article-title":"Standard method for initial efficiency measurements on flatsheet media","author":"Nicholson","year":"1986"},{"key":"10.1016\/j.ajic.2021.07.012_bib0016","unstructured":"Health Canada [Internet] Ottawa, Important Regulatory Considerations for the Reprocessing of Single Use N95 Respirators during the COVID-19 Response: Notice; 2020. Available at: https:\/\/www.canada.ca\/en\/health-canada\/services\/drugs-health-products\/medical-devices\/activities\/announcements\/covid19-notice-reprocessing-n95-respirators.html. Accessed August 24, 2021."},{"key":"10.1016\/j.ajic.2021.07.012_bib0017","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1038\/s41586-020-2196-x","article-title":"Virological assessment of hospitalized patients with COVID-2019","volume":"581","author":"W\u00f6lfel","year":"2020","journal-title":"Nature"},{"key":"10.1016\/j.ajic.2021.07.012_bib0018","unstructured":"US Centers for Disease Control and Prevention [Internet], Atlanta: recommended guidance for extended use and limited reuse of N95 filtering facepiece respirators in healthcare settings; 2020. Available at: https:\/\/www.cdc.gov\/niosh\/topics\/hcwcontrols\/recommendedguidanceextuse.html. Accessed August 24, 2021."},{"key":"10.1016\/j.ajic.2021.07.012_bib0019","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1080\/15459624.2020.1829633","article-title":"The impact of extreme reuse and extended wear conditions on protection provided by a surgical-style N95 filtering facepiece respirator","volume":"17","author":"Duncan","year":"2020","journal-title":"J Occup Environ Hyg"}],"container-title":["American Journal of Infection Control"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0196655321004867?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0196655321004867?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T05:55:51Z","timestamp":1759298151000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0196655321004867"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,10]]},"references-count":19,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2021,10]]}},"alternative-id":["S0196655321004867"],"URL":"https:\/\/doi.org\/10.1016\/j.ajic.2021.07.012","relation":{},"ISSN":["0196-6553"],"issn-type":[{"value":"0196-6553","type":"print"}],"subject":[],"published":{"date-parts":[[2021,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Vapourized hydrogen peroxide decontamination in a hospital setting inactivates SARS-CoV-2 and HCoV-229E without compromising filtration efficiency of unexpired N95 respirators","name":"articletitle","label":"Article Title"},{"value":"American Journal of Infection Control","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajic.2021.07.012","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}