{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,5]],"date-time":"2026-07-05T04:52:24Z","timestamp":1783227144536,"version":"3.54.6"},"reference-count":25,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T00:00:00Z","timestamp":1656633600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T00:00:00Z","timestamp":1656633600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,6,18]],"date-time":"2023-06-18T00:00:00Z","timestamp":1687046400000},"content-version":"am","delay-in-days":352,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["ajicjournal.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["American Journal of Infection Control"],"published-print":{"date-parts":[[2022,7]]},"DOI":"10.1016\/j.ajic.2021.11.019","type":"journal-article","created":{"date-parts":[[2021,12,2]],"date-time":"2021-12-02T02:23:57Z","timestamp":1638411837000},"page":"772-776","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"title":["Effect of the introduction of a management bundle for blood culture collection"],"prefix":"10.1016","volume":"50","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4478-624X","authenticated-orcid":false,"given":"Kenta","family":"Minami","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomoyuki","family":"Yamada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyouhei","family":"Yoshioka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fumiko","family":"Kawanishi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taku","family":"Ogawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akira","family":"Ukimura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ajic.2021.11.019_bib0001","doi-asserted-by":"crossref","first-page":"3277","DOI":"10.1097\/CCM.0b013e318270e771","article-title":"Current approaches to the diagnosis of bacterial and fungal bloodstream infections in the intensive care unit","volume":"40","author":"Murray","year":"2012","journal-title":"Crit Care Med"},{"key":"10.1016\/j.ajic.2021.11.019_bib0002","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1016\/j.amjmed.2010.03.021","article-title":"The clinical and prognostic importance of positive blood cultures in adults","volume":"123","author":"Pien","year":"2010","journal-title":"Am J Med"},{"key":"10.1016\/j.ajic.2021.11.019_bib0003","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1146\/annurev.med.50.1.223","article-title":"Coagulase-negative staphylococci: role as pathogens","volume":"50","author":"Huebner","year":"1999","journal-title":"Annu Rev Med"},{"key":"10.1016\/j.ajic.2021.11.019_bib0004","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1086\/502605","article-title":"Nosocomial bacteremia: clinical significance of a single blood culture positive for coagulase-negative staphylococci","volume":"26","author":"Favre","year":"2005","journal-title":"Infect Control Hosp Epidemiol"},{"key":"10.1016\/j.ajic.2021.11.019_bib0005","doi-asserted-by":"crossref","first-page":"3255","DOI":"10.1128\/JCM.01045-09","article-title":"Differentiating culture samples representing coagulase-negative staphylococcal bacteremia from those representing contamination by use of time-to-positivity and quantitative blood culture methods","volume":"47","author":"Kassis","year":"2009","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.ajic.2021.11.019_bib0006","doi-asserted-by":"crossref","first-page":"1222","DOI":"10.1016\/j.ajic.2015.06.030","volume":"43","author":"Garcia","year":"2015","journal-title":"Am J Infect Control"},{"key":"10.1016\/j.ajic.2021.11.019_bib0007","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1001\/jama.1991.03460030071031","article-title":"Contaminant blood cultures and resource utilization. The true consequences of false-positive results","volume":"265","author":"Bates","year":"1991","journal-title":"Jama"},{"key":"10.1016\/j.ajic.2021.11.019_bib0008","doi-asserted-by":"crossref","first-page":"963","DOI":"10.1016\/j.ajic.2018.12.020","article-title":"Economic health care costs of blood culture contamination: a systematic review","volume":"47","author":"Dempsey","year":"2019","journal-title":"Am J Infect Control"},{"key":"10.1016\/j.ajic.2021.11.019_bib0009","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/S0140-6736(96)08268-2","article-title":"An alternative strategy for studying adverse events in medical care","volume":"349","author":"Andrews","year":"1997","journal-title":"Lancet (London, England)"},{"key":"10.1016\/j.ajic.2021.11.019_bib0010","first-page":"33","article-title":"Practical guidance for clinical microbiology laboratories: a comprehensive update on the problem of blood culture contamination and a discussion of methods for addressing the problem","author":"Doern","year":"2019","journal-title":"Clin Microbiol Rev"},{"key":"10.1016\/j.ajic.2021.11.019_bib0011","doi-asserted-by":"crossref","DOI":"10.1128\/JCM.01015-18","article-title":"Estimated clinical and economic impact through use of a novel blood collection device to reduce blood culture contamination in the emergency department: a cost-benefit analysis","volume":"57","author":"Skoglund","year":"2019","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.ajic.2021.11.019_bib0012","doi-asserted-by":"crossref","first-page":"822","DOI":"10.1016\/j.ajic.2018.12.004","article-title":"Reducing blood culture contamination using an initial specimen diversion device","volume":"47","author":"Zimmerman","year":"2019","journal-title":"Am J Infect Control"},{"key":"10.1016\/j.ajic.2021.11.019_bib0013","doi-asserted-by":"crossref","first-page":"73","DOI":"10.17161\/kjm.vol1413804","article-title":"Evaluation of an Initial Specimen Diversion Device (ISDD) on Rates of Blood Culture Contamination in the Emergency Department","volume":"14","author":"Buzard","year":"2021","journal-title":"Kansas J Med"},{"key":"10.1016\/j.ajic.2021.11.019_bib0014","doi-asserted-by":"crossref","first-page":"999","DOI":"10.1016\/j.clinbiochem.2012.06.007","article-title":"Effectiveness of practices to reduce blood culture contamination: a Laboratory Medicine Best Practices systematic review and meta-analysis","volume":"45","author":"Snyder","year":"2012","journal-title":"Clin Biochem"},{"key":"10.1016\/j.ajic.2021.11.019_bib0015","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1086\/677161","article-title":"Cost analysis of strategies to reduce blood culture contamination in the emergency department: sterile collection kits and phlebotomy teams","volume":"35","author":"Self","year":"2014","journal-title":"Infect Control Hosp Epidemiol"},{"key":"10.1016\/j.ajic.2021.11.019_bib0016","first-page":"999","article-title":"Blood culture quality improvement: a College of American Pathologists Q-Probes study involving 909 institutions and 289 572 blood culture sets","volume":"120","author":"Schifman","year":"1996","journal-title":"Arch Pathol Lab Med"},{"key":"10.1016\/j.ajic.2021.11.019_bib0017","doi-asserted-by":"crossref","first-page":"1222","DOI":"10.5858\/2005-129-1222-TIBCCA","article-title":"Trends in blood culture contamination: a College of American Pathologists Q-Tracks study of 356 institutions","volume":"129","author":"Bekeris","year":"2005","journal-title":"Arch Pathol Lab Med"},{"key":"10.1016\/j.ajic.2021.11.019_bib0018","doi-asserted-by":"crossref","first-page":"1290","DOI":"10.5858\/2001-125-1290-SBC","article-title":"Solitary blood cultures: a College of American Pathologists Q-probes study of 132,778 blood culture sets in 333 small hospitals","volume":"125","author":"Novis","year":"2001","journal-title":"Arch Pathol Lab Med"},{"key":"10.1016\/j.ajic.2021.11.019_bib0019","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1016\/j.cmi.2019.09.005","article-title":"A simplified blood culture sampling protocol for reducing contamination and costs: a randomized controlled trial","volume":"26","author":"Lalezari","year":"2020","journal-title":"Clin Microbiol Infect"},{"key":"10.1016\/j.ajic.2021.11.019_bib0020","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1136\/jcp.2007.047647","article-title":"Peripheral blood culture contamination in adults and venepuncture technique: prospective cohort study","volume":"61","author":"Qamruddin","year":"2008","journal-title":"J Clin Pathol"},{"key":"10.1016\/j.ajic.2021.11.019_bib0021","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1146\/annurev.mi.42.100188.002301","article-title":"Microbial ecology of the skin","volume":"42","author":"Roth","year":"1988","journal-title":"Annu Rev Microbiol"},{"key":"10.1016\/j.ajic.2021.11.019_bib0022","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/j.jhin.2010.10.015","article-title":"Skin antiseptics in venous puncture-site disinfection for prevention of blood culture contamination: systematic review with meta-analysis","volume":"77","author":"Caldeira","year":"2011","journal-title":"J Hosp Infect"},{"key":"10.1016\/j.ajic.2021.11.019_bib0023","doi-asserted-by":"crossref","first-page":"834","DOI":"10.7326\/0003-4819-131-11-199912070-00006","article-title":"Chlorhexidine compared with povidone-iodine as skin preparation before blood culture. A randomized, controlled trial","volume":"131","author":"Mimoz","year":"1999","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.ajic.2021.11.019_bib0024","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1093\/clind\/24.4.584","article-title":"The clinical significance of positive blood cultures in the 1990s: a prospective comprehensive evaluation of the microbiology, epidemiology, and outcome of bacteremia and fungemia in adults","volume":"24","author":"Weinstein","year":"1997","journal-title":"Clin Inf. dis"},{"key":"10.1016\/j.ajic.2021.11.019_bib0025","doi-asserted-by":"crossref","first-page":"6211","DOI":"10.1038\/s41598-021-85614-7","article-title":"Sites of blood collection and topical antiseptics associated with contaminated cultures: prospective observational study","volume":"11","author":"Ota","year":"2021","journal-title":"Sci Rep"}],"container-title":["American Journal of Infection Control"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0196655321007860?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0196655321007860?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T05:57:21Z","timestamp":1759298241000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0196655321007860"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,7]]},"references-count":25,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2022,7]]}},"alternative-id":["S0196655321007860"],"URL":"https:\/\/doi.org\/10.1016\/j.ajic.2021.11.019","relation":{},"ISSN":["0196-6553"],"issn-type":[{"value":"0196-6553","type":"print"}],"subject":[],"published":{"date-parts":[[2022,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effect of the introduction of a management bundle for blood culture collection","name":"articletitle","label":"Article Title"},{"value":"American Journal of Infection Control","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajic.2021.11.019","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}