{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,21]],"date-time":"2026-03-21T17:57:11Z","timestamp":1774115831880,"version":"3.50.1"},"reference-count":21,"publisher":"Elsevier BV","issue":"11","license":[{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100007582","name":"Alberta Health Services","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007582","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["ajicjournal.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["American Journal of Infection Control"],"published-print":{"date-parts":[[2023,11]]},"DOI":"10.1016\/j.ajic.2023.04.167","type":"journal-article","created":{"date-parts":[[2023,4,25]],"date-time":"2023-04-25T12:56:06Z","timestamp":1682427366000},"page":"1213-1217","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["Impact of Clostridioides difficile length of treatment on rates of recurrence in patients on concurrent antibiotics"],"prefix":"10.1016","volume":"51","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4666-8391","authenticated-orcid":false,"given":"Irina","family":"Rajakumar","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rami","family":"Jaber","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raafi","family":"Ali","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elissa","family":"Rennert-May","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Deana","family":"Sabuda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ajic.2023.04.167_bib1","doi-asserted-by":"crossref","first-page":"S12","DOI":"10.1086\/521863","article-title":"Clinical recognition and diagnosis of Clostridium difficile infection","volume":"46","author":"Bartlett","year":"2008","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.ajic.2023.04.167_bib2","doi-asserted-by":"crossref","first-page":"1359","DOI":"10.1001\/jamainternmed.2013.7056","article-title":"Epidemiology of community-associated Clostridium difficile infection, 2009 through 2011","volume":"173","author":"Chitnis","year":"2013","journal-title":"JAMA Intern Med"},{"key":"10.1016\/j.ajic.2023.04.167_bib3","first-page":"99","article-title":"Clostridioides (Clostridium) difficile infection in adults","author":"DynaMed","year":"2022","journal-title":"EBSCO Inf Serv"},{"key":"10.1016\/j.ajic.2023.04.167_bib4","doi-asserted-by":"crossref","first-page":"1135","DOI":"10.1017\/ice.2019.178","article-title":"Attributable costs and length of stay of hospital-acquired Clostridioides difficile: a population-based matched cohort study in Alberta, Canada","volume":"40","author":"Leal","year":"2019","journal-title":"Infect Control Hosp Epidemiol"},{"key":"10.1016\/j.ajic.2023.04.167_bib5","doi-asserted-by":"crossref","first-page":"ofv076","DOI":"10.1093\/ofid\/ofv076","article-title":"Incidence and costs of Clostridium difficile infections in Canada","volume":"2","author":"Levy","year":"2015","journal-title":"Open Forum Infect Dis"},{"key":"10.1016\/j.ajic.2023.04.167_bib6","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1093\/cid\/cir301","article-title":"Cumulative antibiotic exposures over time and the risk of clostridium difficile infection","volume":"53","author":"Stevens","year":"2011","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.ajic.2023.04.167_bib7","doi-asserted-by":"crossref","first-page":"742","DOI":"10.1093\/jac\/dkr508","article-title":"Time interval of increased risk for Clostridium difficile infection after exposure to antibiotics","volume":"67","author":"Hensgens","year":"2012","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.ajic.2023.04.167_bib8","doi-asserted-by":"crossref","first-page":"1106","DOI":"10.1016\/j.mayocp.2012.07.016","article-title":"Clostridium difficile infection: new insights into management","volume":"87","author":"Khanna","year":"2012","journal-title":"Mayo Clin Proc"},{"key":"10.1016\/j.ajic.2023.04.167_bib9","doi-asserted-by":"crossref","first-page":"2326","DOI":"10.1128\/AAC.02176-12","article-title":"Meta-analysis of antibiotics and the risk of community-associated Clostridium difficile infection","volume":"57","author":"Brown","year":"2013","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.ajic.2023.04.167_bib10","doi-asserted-by":"crossref","first-page":"10417","DOI":"10.7189\/jogh.07.010417","article-title":"Risk factors for Clostridium difficile infections\u2014an overview of the evidence base and challenges in data synthesis","volume":"7","author":"Eze","year":"2017","journal-title":"J Glob Health"},{"key":"10.1016\/j.ajic.2023.04.167_bib11","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1093\/cid\/cix1085","article-title":"Clinical practice guidelines for Clostridium difficile infection in adults and children: 2017 update by the Infectious Diseases Society of America (IDSA) and Society for Healthcare Epidemiology of America (SHEA)","volume":"66","author":"McDonald","year":"2018","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.ajic.2023.04.167_bib12","first-page":"116","article-title":"ACG clinical guidelines: prevention, diagnosis, and treatment of Clostridioides difficile infections","author":"Kelly","year":"2021","journal-title":"Off J Am Coll Gastroenterol ACG"},{"key":"10.1016\/j.ajic.2023.04.167_bib13","first-page":"71","article-title":"Association of medical microbiology and infectious disease Canada treatment practice guidelines for Clostridium difficile infection","volume":"3","author":"Loo","year":"2018","journal-title":"J Assoc Med Microbiol Infect Dis Canada"},{"key":"10.1016\/j.ajic.2023.04.167_bib14","doi-asserted-by":"crossref","DOI":"10.1016\/S1473-3099(22)00274-2","article-title":"How can patients with Clostridioides difficile infection on concomitant antibiotic treatment be best managed","author":"Fitzpatrick","year":"2022","journal-title":"Lancet Infect Dis"},{"key":"10.1016\/j.ajic.2023.04.167_bib15","first-page":"1","article-title":"Does prolonging the duration of C difficile infection treatment decrease recurrences in patients receiving concurrent antibiotics?","volume":"3","author":"Rafael","year":"2012"},{"key":"10.1016\/j.ajic.2023.04.167_bib16","first-page":"1","article-title":"Does extending Clostridium difficile treatment in patients who are receiving concomitant antibiotics reduce the rate of relapse","volume":"15","author":"Kaki","year":"2016","journal-title":"Internet J Infect Dis"},{"key":"10.1016\/j.ajic.2023.04.167_bib17","doi-asserted-by":"crossref","first-page":"183","DOI":"10.3390\/antibiotics11020183","article-title":"Oral vancomycin prophylaxis for primary and secondary prevention of Clostridioides difficile infection in patients treated with systemic antibiotic therapy: a systematic review, meta-analysis and trial sequential analysis","volume":"11","author":"Maraolo","year":"2022","journal-title":"Antibiotics"},{"key":"10.1016\/j.ajic.2023.04.167_bib18","first-page":"1","article-title":"Surveillance for Clostridioides difficile infection (CDI)","author":"Canadian Nosocomial Infection Surveillance Program","year":"2022","journal-title":"Public Heath Agency of Canada"},{"key":"10.1016\/j.ajic.2023.04.167_bib19","unstructured":"Alberta Health Services\/Covenant Health\u2014Provincial Surveillance Clostridium difficile infection Protocol. Accessed April 4, 2023. https:\/\/www.albertahealthservices.ca\/assets\/healthinfo\/ipc\/hi-ipc-sr-cdi-protocol.pdf."},{"key":"10.1016\/j.ajic.2023.04.167_bib20","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1097\/01.ccm.0000528659.90565.f1","article-title":"644: Outcomes in prolonged treatment of Clostridium difficile infections with concurrent antibiotic use","volume":"46","author":"Johnson","year":"2018","journal-title":"Crit Care Med"},{"key":"10.1016\/j.ajic.2023.04.167_bib21","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1016\/j.ajic.2019.09.029","article-title":"Hospital-acquired Clostridioides difficile infections in Alberta: the validity of laboratory-identified event surveillance versus clinical infection surveillance","volume":"48","author":"Almon","year":"2020","journal-title":"Am J Infect Control"}],"container-title":["American Journal of Infection Control"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S019665532300336X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S019665532300336X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T06:35:04Z","timestamp":1759300504000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S019665532300336X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,11]]},"references-count":21,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2023,11]]}},"alternative-id":["S019665532300336X"],"URL":"https:\/\/doi.org\/10.1016\/j.ajic.2023.04.167","relation":{},"ISSN":["0196-6553"],"issn-type":[{"value":"0196-6553","type":"print"}],"subject":[],"published":{"date-parts":[[2023,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Impact of Clostridioides difficile length of treatment on rates of recurrence in patients on concurrent antibiotics","name":"articletitle","label":"Article Title"},{"value":"American Journal of Infection Control","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajic.2023.04.167","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}