{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T17:06:08Z","timestamp":1787763968876,"version":"build-2784847793"},"reference-count":33,"publisher":"Elsevier BV","issue":"12","license":[{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100003787","name":"Natural Science Foundation of Hebei Province","doi-asserted-by":"publisher","award":["H2022206358"],"award-info":[{"award-number":["H2022206358"]}],"id":[{"id":"10.13039\/501100003787","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100014882","name":"Department of Finance of Hebei","doi-asserted-by":"publisher","award":["361004"],"award-info":[{"award-number":["361004"]}],"id":[{"id":"10.13039\/501100014882","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["ajicjournal.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["American Journal of Infection Control"],"published-print":{"date-parts":[[2025,12]]},"DOI":"10.1016\/j.ajic.2025.07.011","type":"journal-article","created":{"date-parts":[[2025,7,25]],"date-time":"2025-07-25T15:10:20Z","timestamp":1753456220000},"page":"1300-1304","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"title":["Sex differences in Acinetobacter baumannii infections: A comprehensive analysis of antibiotic resistance patterns in Hebei Province, China"],"prefix":"10.1016","volume":"53","author":[{"given":"Xiaoxuan","family":"Liu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pu","family":"Qin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hainan","family":"Wen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weigang","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiuyue","family":"Huo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qianqing","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianhong","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ajic.2025.07.011_bib1","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1128\/CMR.00058-16","article-title":"Clinical and pathophysiological overview of acinetobacter infections: a century of challenges","volume":"30","author":"Wong","year":"2017","journal-title":"Clin Microbiol Rev"},{"key":"10.1016\/j.ajic.2025.07.011_bib2","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1128\/AAC.48.3.753-757.2004","article-title":"In vitro double and triple synergistic activities of polymyxin B, imipenem, and rifampin against multidrug-resistant Acinetobacter baumannii","volume":"48","author":"Yoon","year":"2004","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.ajic.2025.07.011_bib3","doi-asserted-by":"crossref","first-page":"659","DOI":"10.4103\/0366-6999.201601","article-title":"Trends in drug resistance of Acinetobacter baumannii over a 10-year period: nationwide data from the China Surveillance of Antimicrobial Resistance Program","volume":"130","author":"Gao","year":"2017","journal-title":"Chin Med J"},{"key":"10.1016\/j.ajic.2025.07.011_bib4","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.1097\/CCM.0000000000000125","article-title":"Risk factors and outcome analysis of Acinetobacter baumannii complex bacteremia in critical patients","volume":"42","author":"Lee","year":"2014","journal-title":"Crit Care Med"},{"key":"10.1016\/j.ajic.2025.07.011_bib5","article-title":"Risk factors for acquisition and mortality of multidrug-resistant Acinetobacter baumannii bacteremia: a retrospective study from a Chinese hospital","volume":"98","author":"Zhou","year":"2019","journal-title":"Medicine"},{"key":"10.1016\/j.ajic.2025.07.011_bib6","doi-asserted-by":"crossref","first-page":"e37","DOI":"10.1016\/j.ajic.2015.11.019","article-title":"Risk factors and outcomes of hospitalized patients with blood infections caused by multidrug-resistant Acinetobacter baumannii complex in a hospital of Northern China","volume":"44","author":"Guo","year":"2016","journal-title":"Am J Infect Control"},{"key":"10.1016\/j.ajic.2025.07.011_bib7","doi-asserted-by":"crossref","first-page":"156","DOI":"10.3389\/fcimb.2017.00156","article-title":"Risk factors, clinical presentation, and outcome of Acinetobacter baumannii bacteremia","volume":"7","author":"Ballouz","year":"2017","journal-title":"Front Cell Infect Microbiol"},{"key":"10.1016\/j.ajic.2025.07.011_bib8","doi-asserted-by":"crossref","DOI":"10.3390\/antibiotics9080514","article-title":"Clinical and economic burden of carbapenem-resistant infection or colonization caused by Klebsiella pneumoniae, Pseudomonas aeruginosa, Acinetobacter baumannii: a multicenter study in China","volume":"9","author":"Zhen","year":"2020","journal-title":"Antibiotics"},{"key":"10.1016\/j.ajic.2025.07.011_bib9","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1016\/S1473-3099(17)30753-3","article-title":"Discovery, research, and development of new antibiotics: the WHO priority list of antibiotic-resistant bacteria and tuberculosis","volume":"18","author":"Tacconelli","year":"2018","journal-title":"Lancet Infect Dis"},{"key":"10.1016\/j.ajic.2025.07.011_bib10","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1186\/s13293-018-0187-5","article-title":"Sexual dimorphism in bacterial infections","volume":"9","author":"V\u00e1zquez-Mart\u00ednez","year":"2018","journal-title":"Biol Sex Differ"},{"key":"10.1016\/j.ajic.2025.07.011_bib11","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pmed.1000199","article-title":"Sexual inequality in tuberculosis","volume":"6","author":"Neyrolles","year":"2009","journal-title":"PLoS Med"},{"key":"10.1016\/j.ajic.2025.07.011_bib12","doi-asserted-by":"crossref","first-page":"1978","DOI":"10.1056\/NEJMoa1106126","article-title":"Effect of estrogen on pseudomonas mucoidy and exacerbations in cystic fibrosis","volume":"366","author":"Chotirmall","year":"2012","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ajic.2025.07.011_bib13","first-page":"1075","article-title":"Change in antimicrobial resistance of Acinetobacter baumannii isolated from blood specimens in Hebei Province from 2016 to 2021","volume":"21","author":"Xiao-xuan","year":"2022","journal-title":"Chin\u00a0J\u00a0Infect\u00a0Control"},{"key":"10.1016\/j.ajic.2025.07.011_bib14","doi-asserted-by":"crossref","first-page":"957","DOI":"10.1016\/j.ajic.2018.04.231","article-title":"Sex bias of Acinetobacter baumannii nosocomial infection","volume":"46","author":"Yuan","year":"2018","journal-title":"Am J Infect Control"},{"key":"10.1016\/j.ajic.2025.07.011_bib15","first-page":"123","article-title":"The prevalence and risk factors of nosocomial Acinetobacter blood stream infections in tertiary teaching hospital in north-eastern Malaysia","volume":"26","author":"Deris","year":"2009","journal-title":"Trop Biomed"},{"key":"10.1016\/j.ajic.2025.07.011_bib16","unstructured":"World Health Organization. Tackling antimicrobial resistance (AMR) together: Working paper 5.0: Enhancing the focus on gender and equity. Geneva: World Health Organization; 2018. Report No.: WHO\/HWSI\/AMR\/2018.3."},{"key":"10.1016\/j.ajic.2025.07.011_bib17","doi-asserted-by":"crossref","DOI":"10.1128\/JCM.00213-21","article-title":"Overview of changes to the Clinical and Laboratory Standards Institute Performance Standards for Antimicrobial Susceptibility Testing, M100, 31st Edition","volume":"59","author":"Humphries","year":"2021","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.ajic.2025.07.011_bib18","first-page":"502","article-title":"Secular trends of age at menarche and age at menopause in women born since 1951 from a county of Shandong Province, China","volume":"55","author":"Xiao-wei","year":"2023","journal-title":"J\u00a0Peking Univ\u00a0(Health Sci)"},{"key":"10.1016\/j.ajic.2025.07.011_bib19","doi-asserted-by":"crossref","first-page":"1130","DOI":"10.1097\/GME.0000000000001829","article-title":"Factors related to age at natural menopause in China: results from the China Kadoorie Biobank","volume":"28","author":"Wang","year":"2021","journal-title":"Menopause"},{"key":"10.1016\/j.ajic.2025.07.011_bib20","first-page":"453","article-title":"Age-related change in the level of serum testosterone","volume":"6","author":"You-ju","year":"2007","journal-title":"J\u00a0Diagn\u00a0Concepts\u00a0Pract"},{"key":"10.1016\/j.ajic.2025.07.011_bib21","first-page":"549","article-title":"The study of serum testosterone concentration in different aged men","volume":"23","author":"Rong","year":"2004","journal-title":"Chin\u00a0J\u00a0Geriatr"},{"key":"10.1016\/j.ajic.2025.07.011_bib22","first-page":"493","article-title":"Investigation of serum free testosterone and bioavailable testosterone levels in healthy adults in Chengdu","volume":"41","author":"Liye","year":"2020","journal-title":"Int\u00a0J\u00a0Lab\u00a0Med"},{"key":"10.1016\/j.ajic.2025.07.011_bib23","doi-asserted-by":"crossref","first-page":"6302","DOI":"10.3390\/ijms24076302","article-title":"Gender-specific impact of sex hormones on the immune system","volume":"24","author":"Sciarra","year":"2023","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.ajic.2025.07.011_bib24","doi-asserted-by":"crossref","first-page":"887","DOI":"10.1089\/jir.2006.26.887","article-title":"Gender difference in cytokine secretion on immune stimulation with LPS and LTA","volume":"26","author":"Aulock","year":"2006","journal-title":"J Interferon Cytokine Res"},{"key":"10.1016\/j.ajic.2025.07.011_bib25","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1038\/nri.2016.90","article-title":"Sex differences in immune responses","volume":"16","author":"Klein","year":"2016","journal-title":"Nat Rev Immunol"},{"key":"10.1016\/j.ajic.2025.07.011_bib26","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1016\/j.coph.2013.05.007","article-title":"Oestrogen and immunomodulation: new mechanisms that impact on peripheral and central immunity","volume":"13","author":"Nadkarni","year":"2013","journal-title":"Curr Opin Pharmacol"},{"key":"10.1016\/j.ajic.2025.07.011_bib27","doi-asserted-by":"crossref","first-page":"549","DOI":"10.3390\/jcm7120549","article-title":"Do androgens modulate the pathophysiological pathways of inflammation? Appraising the contemporary evidence","volume":"7","author":"Traish","year":"2018","journal-title":"J Clin Med"},{"key":"10.1016\/j.ajic.2025.07.011_bib28","doi-asserted-by":"crossref","DOI":"10.1172\/jci.insight.132223","article-title":"Biological sex influences susceptibility to Acinetobacter baumannii pneumonia in mice","volume":"5","author":"Pires","year":"2020","journal-title":"JCI Insight"},{"key":"10.1016\/j.ajic.2025.07.011_bib29","doi-asserted-by":"crossref","first-page":"894","DOI":"10.3390\/microorganisms9050894","article-title":"Bugs that can resist antibiotics but not men: gender-specific differences in notified infections and colonisations in Germany, 2010-2019","volume":"9","author":"Brandl","year":"2021","journal-title":"Microorganisms"},{"key":"10.1016\/j.ajic.2025.07.011_bib30","doi-asserted-by":"crossref","first-page":"1800","DOI":"10.1093\/jac\/dkw054","article-title":"Gender differences in antibiotic prescribing in the community: a systematic review and meta-analysis","volume":"71","author":"Schr\u00f6der","year":"2016","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.ajic.2025.07.011_bib31","doi-asserted-by":"crossref","DOI":"10.3389\/fcimb.2021.738223","article-title":"Antibiotic resistance and virulence profiles of Klebsiella pneumoniae strains isolated from different clinical sources","volume":"11","author":"Ball\u00e9n","year":"2021","journal-title":"Front Cell Infect Microbiol"},{"key":"10.1016\/j.ajic.2025.07.011_bib32","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1186\/s12879-017-2932-5","article-title":"A multi-center study on the risk factors of infection caused by multi-drug resistant Acinetobacter baumannii","volume":"18","author":"Huang","year":"2018","journal-title":"BMC Infect Dis"},{"key":"10.1016\/j.ajic.2025.07.011_bib33","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.maturitas.2022.10.009","article-title":"Frailty and the risk of infection-related hospitalizations in older age: differences by sex","volume":"168","author":"Trevisan","year":"2023","journal-title":"Maturitas"}],"container-title":["American Journal of Infection Control"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0196655325004961?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0196655325004961?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T12:59:45Z","timestamp":1772801985000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0196655325004961"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12]]},"references-count":33,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2025,12]]}},"alternative-id":["S0196655325004961"],"URL":"https:\/\/doi.org\/10.1016\/j.ajic.2025.07.011","relation":{},"ISSN":["0196-6553"],"issn-type":[{"value":"0196-6553","type":"print"}],"subject":[],"published":{"date-parts":[[2025,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Sex differences in Acinetobacter baumannii infections: A comprehensive analysis of antibiotic resistance patterns in Hebei Province, China","name":"articletitle","label":"Article Title"},{"value":"American Journal of Infection Control","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajic.2025.07.011","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Published by Elsevier Inc. on behalf of Association for Professionals in Infection Control and Epidemiology, Inc.","name":"copyright","label":"Copyright"}]}}