{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T02:23:03Z","timestamp":1773282183156,"version":"3.50.1"},"reference-count":21,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2004,10,1]],"date-time":"2004-10-01T00:00:00Z","timestamp":1096588800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2004,10,1]],"date-time":"2004-10-01T00:00:00Z","timestamp":1096588800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["ajo.com","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["American Journal of Ophthalmology"],"published-print":{"date-parts":[[2004,10]]},"DOI":"10.1016\/j.ajo.2004.04.071","type":"journal-article","created":{"date-parts":[[2004,10,14]],"date-time":"2004-10-14T11:18:48Z","timestamp":1097752728000},"page":"547-553","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":27,"title":["Corneal pharmacokinetics of topically applied azithromycin and clarithromycin"],"prefix":"10.1016","volume":"138","author":[{"given":"Jonas J.","family":"Kuehne","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna Lisa T.","family":"Yu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gary N.","family":"Holland","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anand","family":"Ramaswamy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryan","family":"Taban","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bartly J.","family":"Mondino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fei","family":"Yu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sylvia A.","family":"Rayner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael J.","family":"Giese","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ajo.2004.04.071_bib1","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1016\/S0002-9394(01)01267-3","article-title":"Cluster of Mycobacterium chelonae keratitis cases following laser in-situ keratomileusis","volume":"132","author":"Chandra","year":"2001","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.ajo.2004.04.071_bib2","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1016\/S0002-9394(99)00390-6","article-title":"Mycobacterium chelonae keratitis after laser in situ keratomileusis successfully treated with medical therapy and flap removal","volume":"129","author":"Chung","year":"2000","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.ajo.2004.04.071_bib3","doi-asserted-by":"crossref","first-page":"1652","DOI":"10.1016\/S0161-6420(98)99034-0","article-title":"Nontuberculous mycobacterial keratitis in South Florida","volume":"105","author":"Ford","year":"1998","journal-title":"Ophthalmology"},{"key":"10.1016\/j.ajo.2004.04.071_bib4","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1016\/S0161-6420(02)01643-3","article-title":"An outbreak of Mycobacterium chelonae infection after LASIK","volume":"110","author":"Freitas","year":"2003","journal-title":"Ophthalmology"},{"key":"10.1016\/j.ajo.2004.04.071_bib5","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1097\/00003226-200208000-00003","article-title":"Delayed-onset mycobacterial keratitis after LASIK","volume":"21","author":"Fulcher","year":"2002","journal-title":"Cornea"},{"key":"10.1016\/j.ajo.2004.04.071_bib6","doi-asserted-by":"crossref","first-page":"191","DOI":"10.3928\/1081-597X-20000301-13","article-title":"Mycobacterium keratitis after laser in situ keratomileusis","volume":"16","author":"Gelender","year":"2000","journal-title":"J Refract Surg"},{"key":"10.1016\/j.ajo.2004.04.071_bib7","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1016\/S0161-6420(02)01760-8","article-title":"Infectious keratitis after LASIK","volume":"110","author":"Karp","year":"2003","journal-title":"Ophthalmology"},{"key":"10.1016\/j.ajo.2004.04.071_bib8","doi-asserted-by":"crossref","first-page":"1266","DOI":"10.1016\/S0161-6420(01)00600-5","article-title":"Infectious keratitis after laser refractive surgery","volume":"108","author":"Kouyoumdjian","year":"2001","journal-title":"Ophthalmology"},{"key":"10.1016\/j.ajo.2004.04.071_bib9","doi-asserted-by":"crossref","first-page":"2201","DOI":"10.1016\/S0161-6420(01)00851-X","article-title":"Mycobacterium interface keratitis after laser in situ keratomileusis","volume":"108","author":"Solomon","year":"2001","journal-title":"Ophthalmology"},{"key":"10.1016\/j.ajo.2004.04.071_bib10","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1016\/S0002-9394(02)01954-2","article-title":"Mycobacterium chelonae interface infection after endokeratoplasty","volume":"135","author":"Busin","year":"2003","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.ajo.2004.04.071_bib11","first-page":"965","article-title":"Corneal pharmacokinetics of topical clarithromycin","volume":"36","author":"Gross","year":"1995","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.ajo.2004.04.071_bib12","doi-asserted-by":"crossref","first-page":"700","DOI":"10.1016\/S0002-9394(14)73469-5","article-title":"Comparison of topical antibiotics for treating Mycobacterium fortuitum keratitis in an animal model","volume":"116","author":"Helm","year":"1993","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.ajo.2004.04.071_bib13","first-page":"377","article-title":"Methods for the study of irritation and toxicity of substances applied to the skin and mucous membranes","volume":"82","author":"Draize","year":"1944","journal-title":"J Pharmacol Exp Toxicol"},{"key":"10.1016\/j.ajo.2004.04.071_bib14","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1046\/j.1365-2885.2002.00387.x","article-title":"Pharmacokinetics of azithromycin in foals after i.v. and oral dose and disposition into phagocytes","volume":"25","author":"Davis","year":"2002","journal-title":"J Vet Pharmacol Ther"},{"key":"10.1016\/j.ajo.2004.04.071_bib15","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1016\/S0731-7085(97)00275-6","article-title":"Azithromycin potency determination: optimal conditions for microbiological diffusion method assay","volume":"17","author":"Turcinov","year":"1998","journal-title":"J Pharm Biomed Anal"},{"key":"10.1016\/j.ajo.2004.04.071_bib16","unstructured":"Lauderdale T, Chapin KC, Murray, PR. Reagents. In: Murray PR, Baron EJ, Pfaller MA, et al, editors. Manual of clinical microbiology, 7th ed. Washington, DC: ASM Press, 1999: 1669."},{"key":"10.1016\/j.ajo.2004.04.071_bib17","unstructured":"Steigbigel NH. Macrolides and clarithromycin. In: Mandell GL, Douglas RG, Bennett JE, Dolin R, editors, 5th ed. Philadelphia: Churchill Livingstone, 2000:371\u2013374."},{"key":"10.1016\/j.ajo.2004.04.071_bib18","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/S0149-2918(96)80179-2","article-title":"Erythromycin, clarithromycin, and azithromycin: are the differences real?","volume":"18","author":"Amsden","year":"1996","journal-title":"Clin Ther"},{"key":"10.1016\/j.ajo.2004.04.071_bib19","doi-asserted-by":"crossref","unstructured":"Brown BA, Wallace RJ Jr, Onyi GO, et al. Activities of four macrolides, including clarithromycin, against Mycobacterium fortuitum, Mycobacterium chelonae, and M. chelonae-like organisms. Antimicrob Agents Chemother 1992;36:180\u2013184.","DOI":"10.1128\/AAC.36.1.180"},{"key":"10.1016\/j.ajo.2004.04.071_bib20","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1016\/S0149-2918(97)80088-4","article-title":"Treatment of nontuberculous mycobacterial infections: role of clarithromycin and azithromycin","volume":"19","author":"Tartaglione","year":"1997","journal-title":"Clin Ther"},{"key":"10.1016\/j.ajo.2004.04.071_bib21","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1093\/jac\/38.3.539","article-title":"Comparative activity of azithromycin against clinical isolates of mycobacteria","volume":"38","author":"Watt","year":"1996","journal-title":"J Antimicrob Chemother"}],"container-title":["American Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002939404005094?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002939404005094?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T12:48:01Z","timestamp":1757594881000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002939404005094"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,10]]},"references-count":21,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2004,10]]}},"alternative-id":["S0002939404005094"],"URL":"https:\/\/doi.org\/10.1016\/j.ajo.2004.04.071","relation":{},"ISSN":["0002-9394"],"issn-type":[{"value":"0002-9394","type":"print"}],"subject":[],"published":{"date-parts":[[2004,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Corneal pharmacokinetics of topically applied azithromycin and clarithromycin","name":"articletitle","label":"Article Title"},{"value":"American Journal of Ophthalmology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajo.2004.04.071","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2004 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}