{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T06:04:15Z","timestamp":1793340255019,"version":"4.5.0"},"reference-count":21,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2005,10,1]],"date-time":"2005-10-01T00:00:00Z","timestamp":1128124800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2005,10,1]],"date-time":"2005-10-01T00:00:00Z","timestamp":1128124800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["ajo.com","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["American Journal of Ophthalmology"],"published-print":{"date-parts":[[2005,10]]},"DOI":"10.1016\/j.ajo.2005.04.051","type":"journal-article","created":{"date-parts":[[2005,10,14]],"date-time":"2005-10-14T07:14:48Z","timestamp":1129274088000},"page":"598.e1-598.e11","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":379,"title":["Persistence and Adherence With Topical Glaucoma Therapy"],"prefix":"10.1016","volume":"140","author":[{"given":"Beth L.","family":"Nordstrom","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David S.","family":"Friedman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Essy","family":"Mozaffari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harry A.","family":"Quigley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander M.","family":"Walker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ajo.2005.04.051_bib1","series-title":"Preferred practice pattern","year":"2003"},{"key":"10.1016\/j.ajo.2005.04.051_bib2","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1016\/S0002-9394(00)00538-9","article-title":"The Advanced Glaucoma Intervention Study (AGIS)","volume":"130","year":"2000","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.ajo.2005.04.051_bib3","doi-asserted-by":"crossref","first-page":"1268","DOI":"10.1001\/archopht.120.10.1268","article-title":"Reduction of intraocular pressure and glaucoma progression","volume":"120","author":"Heijl","year":"2002","journal-title":"Arch Ophthalmol"},{"key":"10.1016\/j.ajo.2005.04.051_bib4","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1097\/00055735-200304000-00006","article-title":"Normal Tension Glaucoma Study. Collaborative normal tension glaucoma study","volume":"14","author":"Anderson","year":"2003","journal-title":"Curr Opin Ophthalmol"},{"key":"10.1016\/j.ajo.2005.04.051_bib5","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1001\/archopht.120.6.701","article-title":"The Ocular Hypertension Treatment Study","volume":"120","author":"Kass","year":"2002","journal-title":"Arch Ophthalmol"},{"key":"10.1016\/j.ajo.2005.04.051_bib6","doi-asserted-by":"crossref","first-page":"711","DOI":"10.2105\/AJPH.83.5.711","article-title":"Treatment for glaucoma","volume":"83","author":"Gurwitz","year":"1993","journal-title":"Am J Public Health"},{"issue":"suppl 10","key":"10.1016\/j.ajo.2005.04.051_bib7","first-page":"S255","article-title":"Population-based persistency rates for topical glaucoma medications measured with pharmacy claims data","volume":"8","author":"Dasgupta","year":"2002","journal-title":"Am J Manag Care"},{"issue":"suppl 10","key":"10.1016\/j.ajo.2005.04.051_bib8","first-page":"S262","article-title":"Rates of discontinuation and change of glaucoma therapy in a managed care setting","volume":"8","author":"Spooner","year":"2002","journal-title":"Am J Manag Care"},{"issue":"suppl 10","key":"10.1016\/j.ajo.2005.04.051_bib9","first-page":"S271","article-title":"Discontinuation rates of topical glaucoma medications in a managed care population","volume":"8","author":"Shaya","year":"2002","journal-title":"Am J Manag Care"},{"issue":"suppl 4","key":"10.1016\/j.ajo.2005.04.051_bib10","doi-asserted-by":"crossref","first-page":"S44","DOI":"10.1177\/112067210301304S05","article-title":"Patient persistency with pharmacotherapy in the management of glaucoma","volume":"13","author":"Reardon","year":"2003","journal-title":"Eur J Ophthalmol"},{"issue":"suppl 1","key":"10.1016\/j.ajo.2005.04.051_bib11","doi-asserted-by":"crossref","first-page":"S3","DOI":"10.1016\/j.ajo.2003.10.035","article-title":"Patient persistency with topical ocular hypotensive therapy in a managed care population","volume":"137","author":"Reardon","year":"2004","journal-title":"Am J Ophthalmol"},{"issue":"suppl 1","key":"10.1016\/j.ajo.2005.04.051_bib12","doi-asserted-by":"crossref","first-page":"S13","DOI":"10.1016\/j.ajo.2003.10.034","article-title":"Persistency with latanoprost or timolol in primary open-angle glaucoma suspects","volume":"137","author":"Schwartz","year":"2004","journal-title":"Am J Ophthalmol"},{"issue":"suppl 4","key":"10.1016\/j.ajo.2005.04.051_bib13","doi-asserted-by":"crossref","first-page":"S21","DOI":"10.1177\/112067210301304S03","article-title":"Persistency and clinical outcomes associated with latanoprost and beta-blocker monotherapy","volume":"13","author":"Diestelhorst","year":"2003","journal-title":"Eur J Ophthalmol"},{"key":"10.1016\/j.ajo.2005.04.051_bib14","doi-asserted-by":"crossref","first-page":"940","DOI":"10.1093\/aje\/kwg074","article-title":"Estimating the relative risk in cohort studies and clinical trials of common outcomes","volume":"157","author":"McNutt","year":"2003","journal-title":"Am J Epidemiol"},{"key":"10.1016\/j.ajo.2005.04.051_bib15","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1097\/00061198-200312000-00003","article-title":"Pooled-data analysis of three randomized, double-masked, six-month studies comparing intraocular pressure-reducing effects of latanoprost and timolol in patients with ocular hypertension","volume":"12","author":"Hedman","year":"2003","journal-title":"J Glaucoma"},{"issue":"suppl 1","key":"10.1016\/j.ajo.2005.04.051_bib16","doi-asserted-by":"crossref","first-page":"S45","DOI":"10.1016\/j.survophthal.2003.12.019","article-title":"Two-year double-masked comparison of bimatoprost with timolol in patients with glaucoma or ocular hypertension","volume":"49","author":"Cohen","year":"2004","journal-title":"Surv Ophthalmol"},{"key":"10.1016\/j.ajo.2005.04.051_bib17","first-page":"123","article-title":"Comparison between latanoprost and brimonidine efficacy and safety in Indian eyes","volume":"51","author":"Thomas","year":"2003","journal-title":"Indian J Ophthalmol"},{"key":"10.1016\/j.ajo.2005.04.051_bib18","first-page":"50","article-title":"Comparison of latanoprost and dorzolamide in the treatment of patients with open angle glaucoma","volume":"16","author":"Niazi","year":"2004","journal-title":"J Ayub Med Coll Abbottabad"},{"key":"10.1016\/j.ajo.2005.04.051_bib19","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1097\/00005650-199803000-00012","article-title":"Patient noncompliance in the managed care setting","volume":"36","author":"Gurwitz","year":"1998","journal-title":"Med Care"},{"key":"10.1016\/j.ajo.2005.04.051_bib20","doi-asserted-by":"crossref","first-page":"1172","DOI":"10.1016\/S0149-2918(03)80074-7","article-title":"Patient persistency with ocular prostaglandin therapy","volume":"25","author":"Reardon","year":"2003","journal-title":"Clin Ther"},{"key":"10.1016\/j.ajo.2005.04.051_bib21","doi-asserted-by":"crossref","first-page":"688","DOI":"10.1016\/S0002-9394(03)00098-9","article-title":"A comparison of latanoprost, bimatoprost, and travoprost in patients with elevated intraocular pressure","volume":"135","author":"Parrish","year":"2003","journal-title":"Am J Ophthalmol"}],"container-title":["American Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S000293940500557X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S000293940500557X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T12:50:40Z","timestamp":1757595040000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S000293940500557X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,10]]},"references-count":21,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2005,10]]}},"alternative-id":["S000293940500557X"],"URL":"https:\/\/doi.org\/10.1016\/j.ajo.2005.04.051","relation":{},"ISSN":["0002-9394"],"issn-type":[{"value":"0002-9394","type":"print"}],"subject":[],"published":{"date-parts":[[2005,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Persistence and Adherence With Topical Glaucoma Therapy","name":"articletitle","label":"Article Title"},{"value":"American Journal of Ophthalmology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajo.2005.04.051","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2005 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}