{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T03:40:05Z","timestamp":1790566805213,"version":"4.1.0"},"reference-count":37,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2007,5,1]],"date-time":"2007-05-01T00:00:00Z","timestamp":1177977600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2007,5,1]],"date-time":"2007-05-01T00:00:00Z","timestamp":1177977600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["ajo.com","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["American Journal of Ophthalmology"],"published-print":{"date-parts":[[2007,5]]},"DOI":"10.1016\/j.ajo.2007.01.015","type":"journal-article","created":{"date-parts":[[2007,3,1]],"date-time":"2007-03-01T16:27:30Z","timestamp":1172766450000},"page":"755-762.e2","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":97,"title":["Therapeutic Keratoplasty for Advanced Suppurative Keratitis"],"prefix":"10.1016","volume":"143","author":[{"given":"Seng-Ei","family":"Ti","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. Angus","family":"Scott","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prathiba","family":"Janardhanan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donald T.H.","family":"Tan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ajo.2007.01.015_bib1","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/0039-6257(89)90129-X","article-title":"Surgical management of corneal ulceration and perforation","volume":"34","author":"Portnoy","year":"1989","journal-title":"Surv Ophthalmol"},{"key":"10.1016\/j.ajo.2007.01.015_bib2","first-page":"736","article-title":"Therapeutic penetrating keratoplasty for microbial keratitis in Taiwan from 1987 to 2001","volume":"137","author":"Chen","year":"2004","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.ajo.2007.01.015_bib3","doi-asserted-by":"crossref","first-page":"1070","DOI":"10.1136\/bjo.85.9.1070","article-title":"Treatment of fungal keratitis by penetrating keratoplasty","volume":"85","author":"Xie","year":"2001","journal-title":"Br J Ophthalmol"},{"key":"10.1016\/j.ajo.2007.01.015_bib4","first-page":"325","article-title":"Therapeutic penetrating keratoplasty in nonhealing corneal ulcer","volume":"26","author":"Panda","year":"1995","journal-title":"Ophthal Surg"},{"key":"10.1016\/j.ajo.2007.01.015_bib5","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1097\/00003226-199611000-00006","article-title":"Results of large penetrating keratoplasty in microbial keratitis","volume":"15","author":"Cristol","year":"1996","journal-title":"Cornea"},{"key":"10.1016\/j.ajo.2007.01.015_bib6","doi-asserted-by":"crossref","first-page":"1276","DOI":"10.1136\/bjo.82.11.1276","article-title":"Corneoscleral transplantation for end stage corneal disease","volume":"82","author":"Hirst","year":"1998","journal-title":"Br J Ophthalmol"},{"key":"10.1016\/j.ajo.2007.01.015_bib7","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1136\/bjo.56.1.41","article-title":"Therapeutic keratoplasty in fungal corneal ulcers","volume":"56","author":"Singh","year":"1972","journal-title":"Br J Ophthalmol"},{"key":"10.1016\/j.ajo.2007.01.015_bib8","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1136\/bjo.87.5.543","article-title":"Therapeutic penetrating keratoplasty in severe fungal keratitis using cryopreserved donor corneas","volume":"87","author":"Yao","year":"2003","journal-title":"Br J Ophthalmol"},{"key":"10.1016\/j.ajo.2007.01.015_bib9","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1016\/S0161-6420(13)31631-5","article-title":"Results of therapeutic penetrating keratoplasty","volume":"100","author":"Killingsworth","year":"1993","journal-title":"Ophthalmology"},{"key":"10.1016\/j.ajo.2007.01.015_bib10","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1136\/bjo.70.7.502","article-title":"Use of penetrating keratoplasty in acute bacterial keratitis","volume":"70","author":"Hill","year":"1986","journal-title":"Br J Ophthalmol"},{"key":"10.1016\/j.ajo.2007.01.015_bib11","doi-asserted-by":"crossref","first-page":"159","DOI":"10.3109\/09286589609080122","article-title":"Incidence of corneal ulceration in Madurai District, South India","volume":"3","author":"Gonzales","year":"1996","journal-title":"Ophthal Epidemiol"},{"key":"10.1016\/j.ajo.2007.01.015_bib12","doi-asserted-by":"crossref","first-page":"1665","DOI":"10.1001\/archopht.1993.01090120087027","article-title":"Incidence of ulcerative keratitis in a defined population from 1950 through 1988","volume":"111","author":"Erie","year":"1993","journal-title":"Arch Ophthalmol"},{"key":"10.1016\/j.ajo.2007.01.015_bib13","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1016\/S0002-9394(14)76903-X","article-title":"Epidemiologic characteristics, predisposing factors and etiologic diagnosis of corneal ulceration in Nepal","volume":"111","author":"Upadhyay","year":"1991","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.ajo.2007.01.015_bib14","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1136\/bjo.81.8.622","article-title":"Corneal ulceration in the developing world: a silent epidemic","volume":"81","author":"Whitcher","year":"1997","journal-title":"Br J Ophthalmol"},{"key":"10.1016\/j.ajo.2007.01.015_bib15","first-page":"214","article-title":"Corneal blindness: a global perspective","volume":"79","author":"Whitcher","year":"2001","journal-title":"Bull World Health Org"},{"key":"10.1016\/j.ajo.2007.01.015_bib16","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1097\/01.ico.0000157407.43699.22","article-title":"Trends in the indications for penetrating keratoplasty, 1980\u20132001","volume":"24","author":"Kang","year":"2005","journal-title":"Cornea"},{"key":"10.1016\/j.ajo.2007.01.015_bib17","doi-asserted-by":"crossref","first-page":"998","DOI":"10.1136\/bjo.2003.031948","article-title":"Penetrating keratoplasty: indications over a 10-year period","volume":"88","author":"Al Yousuf","year":"2004","journal-title":"Br J Ophthalmol"},{"key":"10.1016\/j.ajo.2007.01.015_bib18","doi-asserted-by":"crossref","first-page":"989","DOI":"10.1097\/01.ico.0000157406.34662.0f","article-title":"Indications of penetrating keratoplasty in Northern India","volume":"24","author":"Sony","year":"2005","journal-title":"Cornea"},{"key":"10.1016\/j.ajo.2007.01.015_bib19","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1007\/s00417-005-1167-0","article-title":"Indications for penetrating keratoplasty in East China, 1994\u20132003","volume":"243","author":"Zhang","year":"2005","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"10.1016\/j.ajo.2007.01.015_bib20","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1111\/j.1600-0420.1997.tb00405.x","article-title":"Graft survival and risk factors of penetrating keratoplasty for microbial keratitis","volume":"75","author":"Lomholt","year":"1997","journal-title":"Acta Ophthalmol Scand"},{"key":"10.1016\/j.ajo.2007.01.015_bib21","doi-asserted-by":"crossref","first-page":"1166","DOI":"10.1016\/S0161-6420(99)90250-6","article-title":"Risk factors in microbial keratitis leading to penetrating keratoplasty","volume":"106","author":"Miedziak","year":"1999","journal-title":"Ophthalmology"},{"key":"10.1016\/j.ajo.2007.01.015_bib22","doi-asserted-by":"crossref","first-page":"1227","DOI":"10.1136\/bjo.2004.047423","article-title":"The role of corticosteroids in fungal keratitis: a different view","volume":"88","author":"Peponis","year":"2004","journal-title":"Br J Ophthalmol"},{"key":"10.1016\/j.ajo.2007.01.015_bib23","doi-asserted-by":"crossref","first-page":"1943","DOI":"10.1016\/S0161-6420(95)30771-3","article-title":"The importance of initial management in the treatment of severe infectious corneal ulcers","volume":"102","author":"McLeod","year":"1995","journal-title":"Ophthalmology"},{"key":"10.1016\/j.ajo.2007.01.015_bib24","doi-asserted-by":"crossref","first-page":"1506","DOI":"10.1001\/archopht.1984.01040031226023","article-title":"Surgical management of peripheral fungal keratitis (keratomycosis)","volume":"102","author":"Sanitato","year":"1984","journal-title":"Arch Ophthalmol"},{"key":"10.1016\/j.ajo.2007.01.015_bib25","doi-asserted-by":"crossref","first-page":"929","DOI":"10.1016\/S0886-3350(02)01225-7","article-title":"Deep lamellar keratoplasty with trypan blue intrastromal staining","volume":"28","author":"Balestrazzi","year":"2002","journal-title":"J Cataract Refract Surg"},{"key":"10.1016\/j.ajo.2007.01.015_bib26","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1136\/bjo.81.3.184","article-title":"Deep lamellar keratoplasty with complete removal of pathological stroma for vision improvement","volume":"81","author":"Sugita","year":"1997","journal-title":"Br J Ophthalmol"},{"key":"10.1016\/j.ajo.2007.01.015_bib27","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1016\/j.ajo.2004.04.014","article-title":"Deep anterior lamellar keratoplasty in a patient with descemetocele following gonococcal keratitis","volume":"138","author":"Tong","year":"2004","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.ajo.2007.01.015_bib28","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1016\/S0886-3350(01)01181-6","article-title":"Big-bubble technique to bare Descemet\u2019s membrane in anterior lamellar keratoplasty","volume":"28","author":"Anwar","year":"2002","journal-title":"J Cataract Refract Surg"},{"key":"10.1016\/j.ajo.2007.01.015_bib29","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1016\/S0002-9394(02)02172-4","article-title":"Therapeutic deep lamellar keratoplasty for cornea perforation","volume":"135","author":"Shimmura","year":"2003","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.ajo.2007.01.015_bib30","doi-asserted-by":"crossref","first-page":"1211","DOI":"10.1136\/bjo.86.11.1211","article-title":"Aetiology of suppurative corneal ulcers in Ghana and South India, and epidemiology of fungal keratitis","volume":"86","author":"Leck","year":"2002","journal-title":"Br J Ophthalmol"},{"key":"10.1016\/j.ajo.2007.01.015_bib31","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1136\/bjo.84.1.54","article-title":"Corneal ulceration in the elderly in Hyderabad, South India","volume":"84","author":"Kunimoto","year":"2000","journal-title":"Br J Ophthalmol"},{"key":"10.1016\/j.ajo.2007.01.015_bib32","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/S0002-9394(14)75075-5","article-title":"Spectrum of microbial keratitis in South Florida","volume":"90","author":"Liesegang","year":"1980","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.ajo.2007.01.015_bib33","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/S0002-9394(00)00397-4","article-title":"The effectiveness of a topical antibiotic irrigating solution in a model of staphylococcal keratitis after lamellar keratectomy","volume":"130","author":"Rao","year":"2000","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.ajo.2007.01.015_bib34","doi-asserted-by":"crossref","first-page":"1721","DOI":"10.1001\/archopht.123.12.1721","article-title":"Intracorneal injection of amphotericin B for recurrent fungal keratitis and endophthalmitis","volume":"123","author":"Garcia-Valenzuela","year":"2005","journal-title":"Arch Ophthalmol"},{"key":"10.1016\/j.ajo.2007.01.015_bib35","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1097\/00003226-200110000-00009","article-title":"Intracameral amphotericin B: initial experience in severe keratomycosis","volume":"20","author":"Kaushik","year":"2001","journal-title":"Cornea"},{"key":"10.1016\/j.ajo.2007.01.015_bib36","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1097\/00003226-200210000-00004","article-title":"Intracameral amphotericin B injection in the management of deep keratomycosis","volume":"21","author":"Kuriakose","year":"2002","journal-title":"Cornea"},{"key":"10.1016\/j.ajo.2007.01.015_bib37","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1016\/S0161-6420(00)00544-3","article-title":"The profile of repeated corneal transplantation","volume":"108","author":"Bersudsky","year":"2001","journal-title":"Ophthalmology"}],"container-title":["American Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002939407000074?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002939407000074?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T12:53:29Z","timestamp":1757595209000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002939407000074"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,5]]},"references-count":37,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2007,5]]}},"alternative-id":["S0002939407000074"],"URL":"https:\/\/doi.org\/10.1016\/j.ajo.2007.01.015","relation":{},"ISSN":["0002-9394"],"issn-type":[{"value":"0002-9394","type":"print"}],"subject":[],"published":{"date-parts":[[2007,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Therapeutic Keratoplasty for Advanced Suppurative Keratitis","name":"articletitle","label":"Article Title"},{"value":"American Journal of Ophthalmology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajo.2007.01.015","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2007 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}