{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,14]],"date-time":"2026-02-14T03:00:37Z","timestamp":1771038037202,"version":"3.50.1"},"reference-count":36,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2007,11,1]],"date-time":"2007-11-01T00:00:00Z","timestamp":1193875200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2007,11,1]],"date-time":"2007-11-01T00:00:00Z","timestamp":1193875200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["ajo.com","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["American Journal of Ophthalmology"],"published-print":{"date-parts":[[2007,11]]},"DOI":"10.1016\/j.ajo.2007.06.038","type":"journal-article","created":{"date-parts":[[2007,8,31]],"date-time":"2007-08-31T07:14:41Z","timestamp":1188544481000},"page":"682-689.e1","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":33,"title":["Antibiotic Susceptibility of Bacterial Isolates from Bacterial Keratitis Cases in a University Hospital in Taiwan"],"prefix":"10.1016","volume":"144","author":[{"given":"Chien-Fan","family":"Fong","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fung-Rong","family":"Hu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chia-Hui","family":"Tseng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I.-Jong","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei-Li","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu-Chih","family":"Hou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ajo.2007.06.038_bib1","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/0039-6257(79)90127-9","article-title":"Initial therapy of suspected microbial corneal ulcers","volume":"24","author":"Baum","year":"1979","journal-title":"Surv Ophthalmol"},{"key":"10.1016\/j.ajo.2007.06.038_bib2","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/0039-6257(79)90128-0","article-title":"Initial therapy of suspected microbial corneal ulcers","volume":"24","author":"Jones","year":"1979","journal-title":"Surv Ophthalmol"},{"key":"10.1016\/j.ajo.2007.06.038_bib3","doi-asserted-by":"crossref","first-page":"1322","DOI":"10.1016\/S0161-6420(87)80019-2","article-title":"Epidemiology of microbial keratitis in Southern California: a multivariate analysis","volume":"94","author":"Ormerod","year":"1987","journal-title":"Ophthalmology"},{"key":"10.1016\/j.ajo.2007.06.038_bib4","first-page":"234","article-title":"Infectious keratitis in Baltimore","volume":"23","author":"Wahl","year":"1991","journal-title":"Ann Ophthalmol"},{"key":"10.1016\/j.ajo.2007.06.038_bib5","doi-asserted-by":"crossref","first-page":"1313","DOI":"10.1016\/S0161-6420(99)00716-2","article-title":"Emerging fluoroquinolone resistance in bacterial keratitis: a 5-year review","volume":"106","author":"Goldstein","year":"1999","journal-title":"Ophthalmology"},{"key":"10.1016\/j.ajo.2007.06.038_bib6","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/S0161-6420(99)90008-8","article-title":"In vitro susceptibility of bacterial keratitis pathogens to ciprofloxacin","volume":"106","author":"Kunimoto","year":"1999","journal-title":"Ophthalmology"},{"key":"10.1016\/j.ajo.2007.06.038_bib7","doi-asserted-by":"crossref","first-page":"1319","DOI":"10.1016\/S0161-6420(99)00717-4","article-title":"Ciprofloxacin-resistant Pseudomonas keratitis","volume":"106","author":"Garg","year":"1999","journal-title":"Ophthalmology"},{"key":"10.1016\/j.ajo.2007.06.038_bib8","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1097\/00003226-199801000-00013","article-title":"In vitro antibiotic susceptibilities of ocular isolates in North and South America","volume":"17","author":"Jensen","year":"1998","journal-title":"Cornea"},{"key":"10.1016\/j.ajo.2007.06.038_bib9","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/j.ajo.2003.09.001","article-title":"Clinical characteristics of microbial keratitis in a university hospital in Taiwan","volume":"137","author":"Fong","year":"2004","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.ajo.2007.06.038_bib10","doi-asserted-by":"crossref","first-page":"814","DOI":"10.1016\/S0161-6420(81)34943-4","article-title":"Decision-making in the management of microbial keratitis","volume":"88","author":"Jones","year":"1981","journal-title":"Ophthalmology"},{"key":"10.1016\/j.ajo.2007.06.038_bib11","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1001\/archopht.1982.01030030079005","article-title":"Ulcerative keratitis: survey of 30 years\u2019 laboratory experience","volume":"100","author":"Asbell","year":"1982","journal-title":"Arch Ophthalmol"},{"key":"10.1016\/j.ajo.2007.06.038_bib12","first-page":"834","article-title":"Corneal ulcer disease in Bangladesh","volume":"15","author":"Katz","year":"1983","journal-title":"Ann Ophthalmol"},{"key":"10.1016\/j.ajo.2007.06.038_bib13","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1097\/00006324-199905000-00013","article-title":"Epidemiologic study of ocular refraction among school children in Taiwan in 1995","volume":"76","author":"Lin","year":"1999","journal-title":"Optom Vis Sci"},{"key":"10.1016\/j.ajo.2007.06.038_bib14","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1111\/j.1442-9071.2006.01143.x","article-title":"Bacteria commonly isolated from keratitis specimens retain antibiotic susceptibility to fluoroquinolones and gentamicin plus cephalothin","volume":"34","author":"Ly","year":"2006","journal-title":"Clin Experiment Ophthalmol"},{"key":"10.1016\/j.ajo.2007.06.038_bib15","first-page":"41","article-title":"A study of bacterial isolates from corneal specimens and their antibiotic resistance profile","volume":"27","author":"Begum","year":"2006","journal-title":"Saudi Med J"},{"key":"10.1016\/j.ajo.2007.06.038_bib16","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1097\/01.icl.0000234002.88643.d0","article-title":"Microbial keratitis pathogens and antibiotic susceptibilities: a 5-year review of cases at an urban county hospital in North Texas","volume":"33","author":"Pachigolla","year":"2007","journal-title":"Eye Contact Lens"},{"key":"10.1016\/j.ajo.2007.06.038_bib17","doi-asserted-by":"crossref","first-page":"1497","DOI":"10.1016\/S0161-6420(00)00179-2","article-title":"Shifting trends in bacterial keratitis in South Florida and emerging resistance to fluoroquinolones","volume":"107","author":"Alexandrakis","year":"2000","journal-title":"Ophthalmology"},{"key":"10.1016\/j.ajo.2007.06.038_bib18","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1097\/00003226-200304000-00014","article-title":"Efficacy of transport media use versus direct inoculation of blood agar plates in the microbiologic evaluation of experimental Streptococcus pneumoniae keratitis","volume":"22","author":"Kuo","year":"2003","journal-title":"Cornea"},{"key":"10.1016\/j.ajo.2007.06.038_bib19","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/S0002-9394(03)00905-X","article-title":"Shifting trends in in vitro antibiotic susceptibilities for common ocular isolates during a period of 15 years","volume":"137","author":"Chalita","year":"2004","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.ajo.2007.06.038_bib20","doi-asserted-by":"crossref","first-page":"842","DOI":"10.1136\/bjo.85.7.842","article-title":"Bacterial keratitis: a prospective clinical and microbiological study","volume":"85","author":"Schaefer","year":"2001","journal-title":"Br J Ophthalmol"},{"key":"10.1016\/j.ajo.2007.06.038_bib21","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1136\/bjo.84.7.687","article-title":"In vitro antibiotic resistance in bacterial keratitis in London","volume":"84","author":"Tuft","year":"2000","journal-title":"Br J Ophthalmol"},{"key":"10.1016\/j.ajo.2007.06.038_bib22","doi-asserted-by":"crossref","first-page":"1066","DOI":"10.1016\/j.ajo.2006.06.056","article-title":"Analysis of bacterial cultures in infectious keratitis, 1997 to 2004","volume":"142","author":"Yeh","year":"2006","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.ajo.2007.06.038_bib23","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1016\/j.ijantimicag.2005.08.016","article-title":"Relationships between antimicrobial use and antimicrobial resistance in gram-negative bacteria causing nosocomial infections from 1991\u20132003 at a university hospital in Taiwan","volume":"26","author":"Hsueh","year":"2005","journal-title":"Int J Antimicrob Agents"},{"key":"10.1016\/j.ajo.2007.06.038_bib24","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/j.diagmicrobio.2003.10.005","article-title":"The status of antimicrobial resistance in Taiwan among gram-negative pathogens: the Taiwan surveillance of antimicrobial resistance (TSAR) program, 2000","volume":"48","author":"Lauderdale","year":"2004","journal-title":"Diagn Microbiol Infect Dis"},{"key":"10.1016\/j.ajo.2007.06.038_bib25","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1016\/S0002-9394(14)76770-4","article-title":"An in vitro study of the potency and stability of fortified ophthalmic antibiotic preparations","volume":"111","author":"Bowe","year":"1991","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.ajo.2007.06.038_bib26","first-page":"34S","article-title":"Clinical evaluation of ciprofloxacin 0.3% ophthalmic solution for treatment of bacterial keratitis","volume":"112","author":"Leibowitz","year":"1991","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.ajo.2007.06.038_bib27","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1016\/0002-9394(76)90016-7","article-title":"The stability of ten antibiotics in artificial tear solutions","volume":"82","author":"Osborn","year":"1976","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.ajo.2007.06.038_bib28","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1097\/00003226-199601000-00012","article-title":"Susceptibility of corneal and conjunctival pathogens to ciprofloxacin","volume":"15","author":"Knauf","year":"1996","journal-title":"Cornea"},{"key":"10.1016\/j.ajo.2007.06.038_bib29","doi-asserted-by":"crossref","first-page":"712","DOI":"10.1016\/S0002-9394(14)70641-5","article-title":"Fluoroquinolones in the treatment of bacterial keratitis","volume":"121","author":"Bower","year":"1996","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.ajo.2007.06.038_bib30","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1016\/S0255-0857(21)02587-1","article-title":"Susceptibility trends of Pseudomonas species from corneal ulcers","volume":"23","author":"Smitha","year":"2005","journal-title":"Indian J Med Microbiol"},{"key":"10.1016\/j.ajo.2007.06.038_bib31","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/S0149-2918(04)90018-5","article-title":"Topical antibacterial therapy for mycobacterial keratitis: potential for surgical prophylaxis and treatment","volume":"26","author":"Abshire","year":"2004","journal-title":"Clin Ther"},{"key":"10.1016\/j.ajo.2007.06.038_bib32","first-page":"81","article-title":"Comparison of disc diffusion and E test methods with agar dilution for antimicrobial susceptibility testing of Haemophilus influenzae","volume":"117","author":"Manoharan","year":"2003","journal-title":"Indian J Med Res"},{"key":"10.1016\/j.ajo.2007.06.038_bib33","doi-asserted-by":"crossref","first-page":"864","DOI":"10.1093\/jac\/dkl330","article-title":"Comparison of three standardized disc susceptibility testing methods for colistin","volume":"58","author":"Tan","year":"2006","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.ajo.2007.06.038_bib34","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1001\/archopht.1997.01100150175004","article-title":"Intracorneal, aqueous humor, and vitreous humor penetration of topical and oral ofloxacin","volume":"115","author":"Donnenfeld","year":"1997","journal-title":"Arch Ophthalmol"},{"key":"10.1016\/j.ajo.2007.06.038_bib35","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1016\/S0002-9394(03)00294-0","article-title":"Gatifloxacin and moxifloxacin: an in vitro susceptibility comparison to levofloxacin, ciprofloxacin, and ofloxacin using bacterial keratitis isolates","volume":"136","author":"Kowalski","year":"2003","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.ajo.2007.06.038_bib36","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1016\/j.ajo.2005.08.081","article-title":"Comparison of topical gatifloxacin 0.3% and ciprofloxacin 0.3% for the treatment of bacterial keratitis","volume":"141","author":"Parmar","year":"2006","journal-title":"Am J Ophthalmol"}],"container-title":["American Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002939407006162?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002939407006162?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T12:54:43Z","timestamp":1757595283000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002939407006162"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,11]]},"references-count":36,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2007,11]]}},"alternative-id":["S0002939407006162"],"URL":"https:\/\/doi.org\/10.1016\/j.ajo.2007.06.038","relation":{},"ISSN":["0002-9394"],"issn-type":[{"value":"0002-9394","type":"print"}],"subject":[],"published":{"date-parts":[[2007,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Antibiotic Susceptibility of Bacterial Isolates from Bacterial Keratitis Cases in a University Hospital in Taiwan","name":"articletitle","label":"Article Title"},{"value":"American Journal of Ophthalmology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajo.2007.06.038","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2007 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}