{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T14:21:35Z","timestamp":1781792495487,"version":"3.54.5"},"reference-count":33,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2009,2,1]],"date-time":"2009-02-01T00:00:00Z","timestamp":1233446400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2009,2,1]],"date-time":"2009-02-01T00:00:00Z","timestamp":1233446400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["ajo.com","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["American Journal of Ophthalmology"],"published-print":{"date-parts":[[2009,2]]},"DOI":"10.1016\/j.ajo.2008.08.003","type":"journal-article","created":{"date-parts":[[2008,10,5]],"date-time":"2008-10-05T04:06:19Z","timestamp":1223179579000},"page":"307-312.e2","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":36,"title":["Treatment of Adult-Onset Acute Macular Retinoschisis in Enhanced S-cone Syndrome With Oral Acetazolamide"],"prefix":"10.1016","volume":"147","author":[{"given":"Alessandro","family":"Iannaccone","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenneth H.","family":"Fung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mari E.","family":"Eyestone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edwin M.","family":"Stone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ajo.2008.08.003_bib1","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/S0002-9394(14)76980-6","article-title":"Diagnostic clinical findings of a new syndrome with night blindness, maculopathy, and enhanced S-cone sensitivity","volume":"110","author":"Marmor","year":"1990","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.ajo.2008.08.003_bib2","first-page":"827","article-title":"SWS (blue) cone hypersensitivity in a newly identified retinal degeneration","volume":"31","author":"Jacobson","year":"1990","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.ajo.2008.08.003_bib3","doi-asserted-by":"crossref","first-page":"1473","DOI":"10.1016\/0042-6989(95)98727-Q","article-title":"Enhanced S-cone syndrome: Evidence for an abnormally large number of S cones","volume":"35","author":"Hood","year":"1995","journal-title":"Vision Res"},{"key":"10.1016\/j.ajo.2008.08.003_bib4","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1016\/S0002-9394(14)72379-7","article-title":"Relatively enhanced S-cone function in the Goldmann-Favre syndrome","volume":"111","author":"Jacobson","year":"1991","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.ajo.2008.08.003_bib5","doi-asserted-by":"crossref","first-page":"1316","DOI":"10.1001\/archopht.121.9.1316","article-title":"Shared mutations in NR2E3 in enhanced S-cone syndrome, Goldmann-Favre syndrome, and many cases of clumped pigmentary retinal degeneration","volume":"121","author":"Sharon","year":"2003","journal-title":"Arch Ophthalmol"},{"key":"10.1016\/j.ajo.2008.08.003_bib6","doi-asserted-by":"crossref","first-page":"1112","DOI":"10.1097\/IAE.0b013e31805f6b79","article-title":"Rebound of cystoid macular edema with continued use of acetazolamide in patients with retinitis pigmentosa","volume":"27","author":"Apushkin","year":"2007","journal-title":"Retina"},{"key":"10.1016\/j.ajo.2008.08.003_bib7","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1136\/bjo.2006.107466","article-title":"Continued use of dorzolamide for the treatment of cystoid macular oedema in patients with retinitis pigmentosa","volume":"91","author":"Fishman","year":"2007","journal-title":"Br J Ophthalmol"},{"key":"10.1016\/j.ajo.2008.08.003_bib8","doi-asserted-by":"crossref","first-page":"850","DOI":"10.1016\/j.ajo.2005.12.030","article-title":"Topical dorzolamide for the treatment of cystoid macular edema in patients with retinitis pigmentosa","volume":"141","author":"Grover","year":"2006","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.ajo.2008.08.003_bib9","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1097\/00006982-199717030-00009","article-title":"Efficacy of dorzolamide hydrochloride in the management of chronic cystoid macular edema in patients with retinitis pigmentosa","volume":"17","author":"Grover","year":"1997","journal-title":"Retina"},{"key":"10.1016\/j.ajo.2008.08.003_bib10","doi-asserted-by":"crossref","first-page":"1190","DOI":"10.1001\/archopht.1988.01060140350030","article-title":"Treatment of chronic macular edema with acetazolamide","volume":"106","author":"Cox","year":"1988","journal-title":"Arch Ophthalmol"},{"key":"10.1016\/j.ajo.2008.08.003_bib11","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1016\/S0161-6420(94)31277-2","article-title":"Effect of methazolamide on chronic macular edema in patients with retinitis pigmentosa","volume":"101","author":"Fishman","year":"1994","journal-title":"Ophthalmology"},{"key":"10.1016\/j.ajo.2008.08.003_bib12","first-page":"1914","article-title":"Long-term effect of acetazolamide in a patient with retinitis pigmentosa","volume":"31","author":"Chen","year":"1990","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.ajo.2008.08.003_bib13","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1007\/s10633-007-9054-0","article-title":"Fundus albipunctatus in a 6-year-old girl due to compound heterozygous mutations in the RDH5 gene","volume":"115","author":"Iannaccone","year":"2007","journal-title":"Doc Ophthalmol"},{"key":"10.1016\/j.ajo.2008.08.003_bib14","doi-asserted-by":"crossref","first-page":"4556","DOI":"10.1016\/j.visres.2006.08.018","article-title":"Retinitis pigmentosa associated with rhodopsin mutations: correlation between phenotypic variability and molecular effects","volume":"46","author":"Iannaccone","year":"2006","journal-title":"Vision Res"},{"key":"10.1016\/j.ajo.2008.08.003_bib15","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1007\/BF00156014","article-title":"New noncorneal HK-loop electrode for clinical electroretinography","volume":"81","author":"Hawlina","year":"1992","journal-title":"Doc Ophthalmol"},{"key":"10.1016\/j.ajo.2008.08.003_bib16","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.1001\/archopht.125.8.1107","article-title":"Clinical and functional findings in choroideremia due to complete deletion of the CHM gene","volume":"125","author":"Mura","year":"2007","journal-title":"Arch Ophthalmol"},{"key":"10.1016\/j.ajo.2008.08.003_bib17","doi-asserted-by":"crossref","first-page":"1604","DOI":"10.1016\/S0161-6420(86)33522-X","article-title":"Automated light- and dark-adapted perimetry for evaluating retinitis pigmentosa","volume":"93","author":"Jacobson","year":"1986","journal-title":"Ophthalmology"},{"key":"10.1016\/j.ajo.2008.08.003_bib18","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1038\/72777","article-title":"Mutation of a nuclear receptor gene, NR2E3, causes enhanced S-cone syndrome, a disorder of retinal cell fate","volume":"24","author":"Haider","year":"2000","journal-title":"Nat Genet"},{"key":"10.1016\/j.ajo.2008.08.003_bib19","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1016\/0014-4835(91)90230-C","article-title":"S-cone\u2013driven but not S-cone type electroretinograms in the enhanced S-cone syndrome","volume":"53","author":"Roman","year":"1991","journal-title":"Exp Eye Res"},{"key":"10.1016\/j.ajo.2008.08.003_bib20","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1073\/pnas.022533099","article-title":"The nuclear receptor NR2E3 plays a role in human retinal photoreceptor differentiation and degeneration","volume":"99","author":"Milam","year":"2002","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.ajo.2008.08.003_bib21","first-page":"425","article-title":"Enhanced S-cone sensitivity syndrome: long-term follow-up, electrophysiological and psychophysical findings","volume":"8","author":"Kellner","year":"1993","journal-title":"Clin Vision Sci"},{"key":"10.1016\/j.ajo.2008.08.003_bib22","first-page":"39","article-title":"The genetics of retinal and optic nerve diseases","volume":"5","author":"Iannaccone","year":"2005","journal-title":"Comp Ophthalmol Update"},{"key":"10.1016\/j.ajo.2008.08.003_bib23","doi-asserted-by":"crossref","first-page":"2082","DOI":"10.1167\/iovs.05-1629","article-title":"Phenotypic variation in enhanced S-cone syndrome","volume":"49","author":"Audo","year":"2008","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.ajo.2008.08.003_bib24","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1097\/00006982-200502000-00011","article-title":"Long-term effect of acetazolamide treatment of patients with uveitic chronic cystoid macular edema is limited by persisting inflammation","volume":"25","author":"Schilling","year":"2005","journal-title":"Retina"},{"key":"10.1016\/j.ajo.2008.08.003_bib25","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1097\/00006982-200406000-00030","article-title":"Treatment of cystoid macular edema with oral acetazolamide in a patient with best vitelliform macular dystrophy","volume":"24","author":"Hori","year":"2004","journal-title":"Retina"},{"key":"10.1016\/j.ajo.2008.08.003_bib26","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1038\/sj.eye.6700464","article-title":"Evaluation of the effect of acetazolamide on cystoid macular oedema in patients with Behcet's disease","volume":"17","author":"Lashay","year":"2003","journal-title":"Eye"},{"key":"10.1016\/j.ajo.2008.08.003_bib27","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1023\/A:1002469503835","article-title":"Treatment of uveitic macular edema with acetazolamide","volume":"97","author":"Zierhut","year":"1999","journal-title":"Doc Ophthalmol"},{"key":"10.1016\/j.ajo.2008.08.003_bib28","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1023\/A:1002143802926","article-title":"The role of carbonic anhydrase inhibitors in the management of macular edema","volume":"97","author":"Wolfensberger","year":"1999","journal-title":"Doc Ophthalmol"},{"key":"10.1016\/j.ajo.2008.08.003_bib29","first-page":"127","article-title":"A direct correlation of the resolution of pseudophakic cystoid macular edema with acetazolamide therapy","volume":"23","author":"Tripathi","year":"1991","journal-title":"Ann Ophthalmol"},{"key":"10.1016\/j.ajo.2008.08.003_bib30","first-page":"153","article-title":"Treatment of chronic macular oedema with low dosage acetazolamide","volume":"238","author":"Gelisken","year":"1990","journal-title":"Bull Soc Belge Ophtalmol"},{"key":"10.1016\/j.ajo.2008.08.003_bib31","first-page":"3401","article-title":"Membrane-bound carbonic anhydrase in human retinal pigment epithelium","volume":"35","author":"Wolfensberger","year":"1994","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.ajo.2008.08.003_bib32","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1097\/01.iae.0000237081.80600.51","article-title":"Use of dorzolamide for patients with X-linked retinoschisis","volume":"26","author":"Apushkin","year":"2006","journal-title":"Retina"},{"key":"10.1016\/j.ajo.2008.08.003_bib33","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1001\/archopht.125.4.571","article-title":"Acetazolamide in the treatment of X-linked retinoschisis maculopathy","volume":"125","author":"Ghajarnia","year":"2007","journal-title":"Arch Ophthalmol"}],"container-title":["American Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002939408006466?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002939408006466?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T12:57:14Z","timestamp":1757595434000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002939408006466"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,2]]},"references-count":33,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2009,2]]}},"alternative-id":["S0002939408006466"],"URL":"https:\/\/doi.org\/10.1016\/j.ajo.2008.08.003","relation":{},"ISSN":["0002-9394"],"issn-type":[{"value":"0002-9394","type":"print"}],"subject":[],"published":{"date-parts":[[2009,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Treatment of Adult-Onset Acute Macular Retinoschisis in Enhanced S-cone Syndrome With Oral Acetazolamide","name":"articletitle","label":"Article Title"},{"value":"American Journal of Ophthalmology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajo.2008.08.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2009 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}