{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T03:57:42Z","timestamp":1793678262880,"version":"4.5.1"},"reference-count":26,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2010,10,1]],"date-time":"2010-10-01T00:00:00Z","timestamp":1285891200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2010,10,1]],"date-time":"2010-10-01T00:00:00Z","timestamp":1285891200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100000053","name":"National Eye Institute","doi-asserted-by":"crossref","award":["EY02162"],"award-info":[{"award-number":["EY02162"]}],"id":[{"id":"10.13039\/100000053","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100000053","name":"National Eye Institute","doi-asserted-by":"crossref","award":["K23EY017897"],"award-info":[{"award-number":["K23EY017897"]}],"id":[{"id":"10.13039\/100000053","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Research to Prevent Blindness Career Development Award"},{"DOI":"10.13039\/100000862","name":"Doris Duke Charitable Foundation","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100000862","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["ajo.com","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["American Journal of Ophthalmology"],"published-print":{"date-parts":[[2010,10]]},"DOI":"10.1016\/j.ajo.2010.04.031","type":"journal-article","created":{"date-parts":[[2010,7,21]],"date-time":"2010-07-21T04:22:29Z","timestamp":1279686149000},"page":"534-542.e2","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":84,"title":["Incidence Rates and Risk Factors for Ocular Complications and Vision Loss in HLA-B27-Associated Uveitis"],"prefix":"10.1016","volume":"150","author":[{"given":"Allison R.","family":"Loh","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nisha R.","family":"Acharya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"6","key":"10.1016\/j.ajo.2010.04.031_bib1","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1097\/00055735-200312000-00010","article-title":"HLA-B27-associated uveitis: overview and current perspectives","volume":"14","author":"Suhler","year":"2003","journal-title":"Curr Opin Ophthalmol"},{"issue":"4","key":"10.1016\/j.ajo.2010.04.031_bib2","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1016\/j.survophthal.2005.04.003","article-title":"Acute anterior uveitis and HLA-B27","volume":"50","author":"Chang","year":"2005","journal-title":"Surv Ophthalmol"},{"issue":"1","key":"10.1016\/j.ajo.2010.04.031_bib3","doi-asserted-by":"crossref","first-page":"127","DOI":"10.3899\/jrheum.080102","article-title":"Uveitis subtypes in a German interdisciplinary uveitis center\u2014analysis of 1916 patients","volume":"36","author":"Jakob","year":"2009","journal-title":"J Rheumatol"},{"issue":"6","key":"10.1016\/j.ajo.2010.04.031_bib4","doi-asserted-by":"crossref","first-page":"890","DOI":"10.1016\/j.ajo.2008.09.014","article-title":"Incidence and prevalence of uveitis in Veterans Affairs Medical Centers of the Pacific Northwest","volume":"146","author":"Suhler","year":"2008","journal-title":"Am J Ophthalmol"},{"issue":"7836","key":"10.1016\/j.ajo.2010.04.031_bib5","doi-asserted-by":"crossref","first-page":"994","DOI":"10.1016\/S0140-6736(73)91090-8","article-title":"Acute anterior uveitis and HL-A 27","volume":"302","author":"Brewerton","year":"1973","journal-title":"Lancet"},{"issue":"1230","key":"10.1016\/j.ajo.2010.04.031_bib6","first-page":"U1886","article-title":"Uveitis screening: HLAB27 antigen and ankylosing spondylitis in a New Zealand population","volume":"119","author":"Niederer","year":"2006","journal-title":"N Z Med J"},{"issue":"5","key":"10.1016\/j.ajo.2010.04.031_bib7","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1007\/BF00917833","article-title":"Epidemiological characteristics of uveitis in Switzerland","volume":"18","author":"Tran","year":"1994","journal-title":"Int Ophthalmol"},{"issue":"5","key":"10.1016\/j.ajo.2010.04.031_bib8","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1001\/archopht.1996.01100130585016","article-title":"Referral patterns of uveitis in a tertiary eye care center","volume":"114","author":"Rodriguez","year":"1996","journal-title":"Arch Ophthalmol"},{"issue":"5","key":"10.1016\/j.ajo.2010.04.031_bib9","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1136\/bjo.59.5.270","article-title":"HL-A 27 and acute anterior uveitis","volume":"59","author":"Mapstone","year":"1975","journal-title":"Br J Ophthalmol"},{"issue":"12","key":"10.1016\/j.ajo.2010.04.031_bib10","doi-asserted-by":"crossref","first-page":"1448","DOI":"10.1136\/bjo.2006.099788","article-title":"HLA-B27-associated acute anterior uveitis in the University Referral Centre in North Thailand: clinical presentation and visual prognosis","volume":"90","author":"Pathanapitoon","year":"2006","journal-title":"Br J Ophthalmol"},{"issue":"1","key":"10.1016\/j.ajo.2010.04.031_bib11","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/S0002-9394(14)70533-1","article-title":"Clinical features and associated systemic diseases of HLA-B27 uveitis","volume":"121","author":"Tay-Kearney","year":"1996","journal-title":"Am J Ophthalmol"},{"issue":"4","key":"10.1016\/j.ajo.2010.04.031_bib12","doi-asserted-by":"crossref","first-page":"802","DOI":"10.1016\/j.ophtha.2003.07.011","article-title":"Ophthalmic findings and frequency of extraocular manifestations in patients with HLA-B27 uveitis: a study of 175 cases","volume":"111","author":"Monnet","year":"2004","journal-title":"Ophthalmology"},{"issue":"3","key":"10.1016\/j.ajo.2010.04.031_bib13","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1016\/j.ajo.2007.11.009","article-title":"Human leukocyte antigen-B27-associated uveitis: long-term follow-up and gender differences","volume":"145","author":"Braakenburg","year":"2008","journal-title":"Am J Ophthalmol"},{"issue":"6","key":"10.1016\/j.ajo.2010.04.031_bib14","doi-asserted-by":"crossref","first-page":"1134","DOI":"10.1016\/S0161-6420(01)00576-0","article-title":"Methotrexate therapy for chronic noninfectious uveitis: analysis of a case series of 160 patients","volume":"108","author":"Samson","year":"2001","journal-title":"Ophthalmology"},{"issue":"9","key":"10.1016\/j.ajo.2010.04.031_bib15","doi-asserted-by":"crossref","first-page":"1646","DOI":"10.1016\/S0161-6420(98)99033-9","article-title":"Outcomes in anterior uveitis associated with the HLA-B27 haplotype","volume":"105","author":"Power","year":"1998","journal-title":"Ophthalmology"},{"issue":"3","key":"10.1016\/j.ajo.2010.04.031_bib16","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1016\/j.ajo.2005.03.057","article-title":"Standardization of uveitis nomenclature for reporting clinical data","volume":"140","author":"Jabs","year":"2005","journal-title":"Am J Ophthalmol"},{"issue":"4","key":"10.1016\/j.ajo.2010.04.031_bib17","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1016\/S0002-9394(00)00659-0","article-title":"Guidelines for the use of immunosuppressive drugs in patients with ocular inflammatory disorders: recommendations of an expert panel","volume":"130","author":"Jabs","year":"2000","journal-title":"Am J Ophthalmol"},{"issue":"5","key":"10.1016\/j.ajo.2010.04.031_bib18","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1016\/j.ajo.2007.01.033","article-title":"Juvenile idiopathic arthritis\u2013associated uveitis: incidence of ocular complications and visual acuity loss","volume":"143","author":"Thorne","year":"2007","journal-title":"Am J Ophthalmol"},{"issue":"6","key":"10.1016\/j.ajo.2010.04.031_bib19","doi-asserted-by":"crossref","first-page":"828","DOI":"10.1016\/j.ajo.2008.06.019","article-title":"Ocular inflammation in Behcet disease: incidence of ocular complications and of loss of visual acuity","volume":"146","author":"Kacmaz","year":"2008","journal-title":"Am J Ophthalmol"},{"issue":"5","key":"10.1016\/j.ajo.2010.04.031_bib20","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1136\/ard.2006.060293","article-title":"Are there gender differences in severity of ankylosing spondylitis?","volume":"66","author":"Lee","year":"2007","journal-title":"Ann Rheum Dis"},{"issue":"4","key":"10.1016\/j.ajo.2010.04.031_bib21","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1016\/j.ajo.2006.11.025","article-title":"Risk factors for ocular complications and poor visual acuity at presentation among patients with uveitis associated with juvenile idiopathic arthritis","volume":"143","author":"Woreta","year":"2007","journal-title":"Am J Ophthalmol"},{"issue":"12","key":"10.1016\/j.ajo.2010.04.031_bib22","doi-asserted-by":"crossref","first-page":"2342","DOI":"10.1016\/S0161-6420(02)01292-7","article-title":"Anti-tumor necrosis factor-alpha therapy with infliximab as an alternative to corticosteroids in the treatment of human leukocyte antigen B27-associated acute anterior uveitis","volume":"109","author":"El-Shabrawi","year":"2002","journal-title":"Ophthalmology"},{"issue":"11","key":"10.1016\/j.ajo.2010.04.031_bib23","doi-asserted-by":"crossref","first-page":"1147","DOI":"10.1007\/s00417-005-0005-8","article-title":"Risk and prognostic factors of poor visual outcome in Behcet's disease with ocular involvement","volume":"243","author":"Takeuchi","year":"2005","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"issue":"2","key":"10.1016\/j.ajo.2010.04.031_bib24","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/S0161-6420(95)31022-6","article-title":"Prognostic factors of vision in patients with Behcet disease","volume":"102","author":"Sakamoto","year":"1995","journal-title":"Ophthalmology"},{"issue":"6","key":"10.1016\/j.ajo.2010.04.031_bib25","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1016\/j.ajo.2008.06.004","article-title":"Interobserver agreement in grading activity and site of inflammation in eyes of patients with uveitis","volume":"146","author":"Kempen","year":"2008","journal-title":"Am J Ophthalmol"},{"issue":"1","key":"10.1016\/j.ajo.2010.04.031_bib26","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1136\/ard.2008.103192","article-title":"Analysis of uveitis rates across all etanercept ankylosing spondylitis clinical trials","volume":"69","author":"Sieper","year":"2010","journal-title":"Ann Rheum Dis"}],"container-title":["American Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002939410003156?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002939410003156?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T13:00:53Z","timestamp":1757595653000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002939410003156"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,10]]},"references-count":26,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2010,10]]}},"alternative-id":["S0002939410003156"],"URL":"https:\/\/doi.org\/10.1016\/j.ajo.2010.04.031","relation":{},"ISSN":["0002-9394"],"issn-type":[{"value":"0002-9394","type":"print"}],"subject":[],"published":{"date-parts":[[2010,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Incidence Rates and Risk Factors for Ocular Complications and Vision Loss in HLA-B27-Associated Uveitis","name":"articletitle","label":"Article Title"},{"value":"American Journal of Ophthalmology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajo.2010.04.031","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2010 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}