{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T13:54:13Z","timestamp":1780667653880,"version":"3.54.1"},"reference-count":32,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2011,3,1]],"date-time":"2011-03-01T00:00:00Z","timestamp":1298937600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2011,3,1]],"date-time":"2011-03-01T00:00:00Z","timestamp":1298937600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2011,3,1]],"date-time":"2011-03-01T00:00:00Z","timestamp":1298937600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2011,3,1]],"date-time":"2011-03-01T00:00:00Z","timestamp":1298937600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2011,3,1]],"date-time":"2011-03-01T00:00:00Z","timestamp":1298937600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2011,3,1]],"date-time":"2011-03-01T00:00:00Z","timestamp":1298937600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2011,3,1]],"date-time":"2011-03-01T00:00:00Z","timestamp":1298937600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"name":"Allergan, Inc"}],"content-domain":{"domain":["ajo.com","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["American Journal of Ophthalmology"],"published-print":{"date-parts":[[2011,3]]},"DOI":"10.1016\/j.ajo.2010.09.003","type":"journal-article","created":{"date-parts":[[2010,12,10]],"date-time":"2010-12-10T04:15:04Z","timestamp":1291954504000},"page":"420-426.e1","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":39,"title":["Twice-Daily, Preservative-Free Ketorolac 0.45% for Treatment of Inflammation and Pain After Cataract Surgery"],"prefix":"10.1016","volume":"151","author":[{"given":"Eric D.","family":"Donnenfeld","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Louis D.","family":"Nichamin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David R.","family":"Hardten","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael B.","family":"Raizman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William","family":"Trattler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rajesh K.","family":"Rajpal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Louis M.","family":"Alpern","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos","family":"Felix","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ronald R.","family":"Bradford","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linda","family":"Villanueva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David A.","family":"Hollander","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rhett M.","family":"Schiffman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.ajo.2010.09.003_bib1","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1097\/00055735-200102000-00002","article-title":"Control of intra-ocular inflammation associated with cataract surgery","volume":"12","author":"El-Harazi","year":"2001","journal-title":"Curr Opin Ophthalmol"},{"issue":"7","key":"10.1016\/j.ajo.2010.09.003_bib2","doi-asserted-by":"crossref","first-page":"790","DOI":"10.1096\/fj.03-0645rev","article-title":"Cyclooxygenases: new forms, new inhibitors, and lessons from the clinic","volume":"18","author":"Warner","year":"2004","journal-title":"FASEB J"},{"issue":"1","key":"10.1016\/j.ajo.2010.09.003_bib3","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1097\/00055735-200002000-00002","article-title":"Control of intraocular inflammation associated with cataract surgery","volume":"11","author":"McColgin","year":"2000","journal-title":"Curr Opin Ophthalmol"},{"issue":"9","key":"10.1016\/j.ajo.2010.09.003_bib4","first-page":"1431","article-title":"Emerging guidelines for use of NSAID therapy to optimize cataract surgery patient care","volume":"21","author":"O'Brien","year":"2005","journal-title":"Erratum in Curr Med Res Opin"},{"issue":"10","key":"10.1016\/j.ajo.2010.09.003_bib5","doi-asserted-by":"crossref","first-page":"2325","DOI":"10.1185\/030079907X226195","article-title":"Clinical comparison of two topical prednisolone acetate 1% formulations in reducing inflammation after cataract surgery","volume":"23","author":"Raizman","year":"2007","journal-title":"Curr Med Res Opin"},{"issue":"1","key":"10.1016\/j.ajo.2010.09.003_bib6","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1097\/00055735-200002000-00010","article-title":"Cystoid macular edema following cataract surgery","volume":"11","author":"Rossetti","year":"2000","journal-title":"Curr Opin Ophthalmol"},{"issue":"1","key":"10.1016\/j.ajo.2010.09.003_bib7","doi-asserted-by":"crossref","first-page":"86","DOI":"10.2165\/00003495-199039010-00008","article-title":"Ketorolac","volume":"39","author":"Buckley","year":"1990","journal-title":"Drugs"},{"key":"10.1016\/j.ajo.2010.09.003_bib8","series-title":"Acular LS [package insert]","year":"2008"},{"key":"10.1016\/j.ajo.2010.09.003_bib9","series-title":"Acular [package insert]","year":"1997"},{"issue":"3","key":"10.1016\/j.ajo.2010.09.003_bib10","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/S0002-9394(98)00413-9","article-title":"Ketorolac tromethamine 0.5% ophthalmic solution in the treatment of moderate to severe ocular inflammation after cataract surgery: a randomized, vehicle-controlled clinical trial","volume":"127","author":"Heier","year":"1999","journal-title":"Am J Ophthalmol"},{"issue":"2","key":"10.1016\/j.ajo.2010.09.003_bib11","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1016\/S0161-6420(00)00543-1","article-title":"Topical ketorolac tromethamine 0.5% ophthalmic solution in ocular inflammation after cataract surgery","volume":"108","author":"Solomon","year":"2001","journal-title":"Ophthalmology"},{"issue":"8","key":"10.1016\/j.ajo.2010.09.003_bib12","doi-asserted-by":"crossref","first-page":"1653","DOI":"10.1016\/j.jcrs.2004.05.019","article-title":"Safety and efficacy of ketorolac tromethamine 0.4% ophthalmic solution in post-photorefractive keratectomy patients","volume":"30","author":"Solomon","year":"2004","journal-title":"J Cataract Refract Surg"},{"issue":"6","key":"10.1016\/j.ajo.2010.09.003_bib13","doi-asserted-by":"crossref","first-page":"1133","DOI":"10.1185\/030079906X112471","article-title":"Comparison of cyclooxygenase inhibitory activity and ocular anti-inflammatory effects of ketorolac tromethamine and bromfenac sodium","volume":"22","author":"Waterbury","year":"2006","journal-title":"Curr Med Res Opin"},{"issue":"4","key":"10.1016\/j.ajo.2010.09.003_bib14","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1016\/j.ajo.2008.04.036","article-title":"A randomized, masked comparison of topical ketorolac 0.4% plus steroid vs steroid alone in low-risk cataract surgery patients","volume":"146","author":"Wittpenn","year":"2008","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.ajo.2010.09.003_bib15","series-title":"Acuvail [package insert]","year":"2009"},{"issue":"11","key":"10.1016\/j.ajo.2010.09.003_bib16","doi-asserted-by":"crossref","first-page":"1352","DOI":"10.1248\/bpb.23.1352","article-title":"Pharmacokinetic prediction of the ocular absorption of an instilled drug with ophthalmic viscous vehicle","volume":"23","author":"Sasaki","year":"2000","journal-title":"Biol Pharm Bull"},{"issue":"12","key":"10.1016\/j.ajo.2010.09.003_bib17","doi-asserted-by":"crossref","first-page":"2015","DOI":"10.1185\/030079904X16759","article-title":"Efficacy of topical ketorolac tromethamine 0.4% for control of pain or discomfort associated with cataract surgery","volume":"20","author":"Price","year":"2004","journal-title":"Curr Med Res Opin"},{"issue":"612","key":"10.1016\/j.ajo.2010.09.003_bib18","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1136\/pgmj.52.612.634","article-title":"Steroids and the eye\u2014indications and complications","volume":"52","author":"Dinning","year":"1976","journal-title":"Postgrad Med J"},{"issue":"9","key":"10.1016\/j.ajo.2010.09.003_bib19","doi-asserted-by":"crossref","first-page":"1474","DOI":"10.1016\/j.jcrs.2006.04.009","article-title":"Preoperative ketorolac tromethamine 0.4% in phacoemulsification outcomes: pharmacokinetic-response curve","volume":"32","author":"Donnenfeld","year":"2006","journal-title":"J Cataract Refract Surg"},{"issue":"1","key":"10.1016\/j.ajo.2010.09.003_bib20","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1517\/14656566.7.1.99","article-title":"An update on the use of ophthalmic ketorolac tromethamine 0.4%","volume":"7","author":"Perry","year":"2006","journal-title":"Expert Opin Pharmacother"},{"issue":"2","key":"10.1016\/j.ajo.2010.09.003_bib21","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1016\/j.jcrs.2007.09.036","article-title":"Separate and additive mydriatic effects of lidocaine hydrochloride, phenylephrine, and cyclopentolate after intracameral injection","volume":"34","author":"Lundberg","year":"2008","journal-title":"J Cataract Refract Surg"},{"issue":"1","key":"10.1016\/j.ajo.2010.09.003_bib22","doi-asserted-by":"crossref","first-page":"63","DOI":"10.4103\/0301-4738.37598","article-title":"Pupil dilation with intracameral lidocaine during phacoemulsification: Benefits for the patient and surgeon","volume":"56","author":"Nikeghbali","year":"2008","journal-title":"Indian J Ophthalmol"},{"issue":"9","key":"10.1016\/j.ajo.2010.09.003_bib23","doi-asserted-by":"crossref","first-page":"1881","DOI":"10.1001\/archinte.1990.00390200073014","article-title":"The effect of prescribed daily dose frequency on patient medication compliance","volume":"150","author":"Eisen","year":"1990","journal-title":"Arch Intern Med"},{"issue":"6","key":"10.1016\/j.ajo.2010.09.003_bib24","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1007\/BF00314990","article-title":"Dosage frequency and drug-compliance behaviour\u2014a comparative study on compliance with a medication to be taken twice or four times daily","volume":"41","author":"Kruse","year":"1991","journal-title":"Eur J Clin Pharmacol"},{"issue":"4","key":"10.1016\/j.ajo.2010.09.003_bib25","doi-asserted-by":"crossref","first-page":"1559","DOI":"10.1167\/iovs.06-0848","article-title":"Carboxymethylcellulose binds to human corneal epithelial cells and is a modulator of corneal epithelial wound healing","volume":"48","author":"Garrett","year":"2007","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"9","key":"10.1016\/j.ajo.2010.09.003_bib26","doi-asserted-by":"crossref","first-page":"1203","DOI":"10.1001\/archopht.126.9.1203","article-title":"Topical ketorolac in vitreoretinal surgery: a prospective, randomized, placebo-controlled, double-masked trial","volume":"126","author":"Kim","year":"2008","journal-title":"Arch Ophthalmol"},{"issue":"7","key":"10.1016\/j.ajo.2010.09.003_bib27","doi-asserted-by":"crossref","first-page":"960","DOI":"10.1016\/S0886-3350(96)80199-4","article-title":"Comparison of the effect of four viscoelastic agents on early postoperative intraocular pressure","volume":"22","author":"Henry","year":"1996","journal-title":"J Cataract Refract Surg"},{"issue":"8","key":"10.1016\/j.ajo.2010.09.003_bib28","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1136\/bjo.58.8.725","article-title":"Early ocular hypertension after cataract extraction","volume":"58","author":"Rich","year":"1974","journal-title":"Br J Ophthalmol"},{"issue":"1","key":"10.1016\/j.ajo.2010.09.003_bib29","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/S0886-3350(03)00498-X","article-title":"Relationship of immediate intraocular pressure rise to phaco-tip ergonomics and energy dissipation","volume":"30","author":"Vasavada","year":"2004","journal-title":"J Cataract Refract Surg"},{"issue":"3","key":"10.1016\/j.ajo.2010.09.003_bib30","first-page":"477","article-title":"Aqueous humor dynamics in experimental iridocyclitis","volume":"28","author":"Toris","year":"1987","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"2","key":"10.1016\/j.ajo.2010.09.003_bib31","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1097\/00004397-200004000-00014","article-title":"Appraisal and management of ocular hypotony and glaucoma associated with uveitis","volume":"40","author":"Tran","year":"2000","journal-title":"Int Ophthalmol Clin"},{"key":"10.1016\/j.ajo.2010.09.003_bib32","series-title":"Nevanac [package insert]","year":"2005"}],"container-title":["American Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002939410006781?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002939410006781?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T13:02:17Z","timestamp":1757595737000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002939410006781"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,3]]},"references-count":32,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2011,3]]}},"alternative-id":["S0002939410006781"],"URL":"https:\/\/doi.org\/10.1016\/j.ajo.2010.09.003","relation":{},"ISSN":["0002-9394"],"issn-type":[{"value":"0002-9394","type":"print"}],"subject":[],"published":{"date-parts":[[2011,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Twice-Daily, Preservative-Free Ketorolac 0.45% for Treatment of Inflammation and Pain After Cataract Surgery","name":"articletitle","label":"Article Title"},{"value":"American Journal of Ophthalmology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajo.2010.09.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2011 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}