{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T05:57:21Z","timestamp":1788587841789,"version":"build-2803163510"},"reference-count":19,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2011,11,1]],"date-time":"2011-11-01T00:00:00Z","timestamp":1320105600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2011,11,1]],"date-time":"2011-11-01T00:00:00Z","timestamp":1320105600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2011,11,1]],"date-time":"2011-11-01T00:00:00Z","timestamp":1320105600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2011,11,1]],"date-time":"2011-11-01T00:00:00Z","timestamp":1320105600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2011,11,1]],"date-time":"2011-11-01T00:00:00Z","timestamp":1320105600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2011,11,1]],"date-time":"2011-11-01T00:00:00Z","timestamp":1320105600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2011,11,1]],"date-time":"2011-11-01T00:00:00Z","timestamp":1320105600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["ajo.com","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["American Journal of Ophthalmology"],"published-print":{"date-parts":[[2011,11]]},"DOI":"10.1016\/j.ajo.2011.04.033","type":"journal-article","created":{"date-parts":[[2011,7,28]],"date-time":"2011-07-28T02:33:24Z","timestamp":1311820404000},"page":"748-755","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":98,"title":["Simultaneous Topography-Guided Photorefractive Keratectomy Followed by Corneal Collagen Cross-linking for Keratoconus"],"prefix":"10.1016","volume":"152","author":[{"given":"George D.","family":"Kymionis","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dimitra M.","family":"Portaliou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"George A.","family":"Kounis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aliki N.","family":"Limnopoulou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Georgios A.","family":"Kontadakis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael A.","family":"Grentzelos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.ajo.2011.04.033_bib1","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1016\/j.ajo.2006.10.041","article-title":"Long-term follow-up of Intacs in keratoconus","volume":"143","author":"Kymionis","year":"2007","journal-title":"Am J Ophthalmol"},{"issue":"4","key":"10.1016\/j.ajo.2011.04.033_bib2","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1097\/ICU.0b013e3281a7ecaa","article-title":"Current treatment options for corneal ectasia","volume":"18","author":"Tan","year":"2007","journal-title":"Curr Opin Ophthalmol"},{"issue":"3","key":"10.1016\/j.ajo.2011.04.033_bib3","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1016\/j.ajo.2009.10.005","article-title":"Quality of life in keratoconus patients after penetrating keratoplasty","volume":"149","author":"Yildiz","year":"2010","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.ajo.2011.04.033_bib4","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1097\/01.icu.0000233954.86723.25","article-title":"Cross inking treatment of progressive keratoconus: new hope","volume":"17","author":"Wollensak","year":"2006","journal-title":"Curr Opin Ophthalmol"},{"issue":"4","key":"10.1016\/j.ajo.2011.04.033_bib5","doi-asserted-by":"crossref","first-page":"371","DOI":"10.3928\/1081597X-20090401-02","article-title":"Contralateral eye study of corneal collagen cross-linking with riboflavin and UVA irradiation in patients with keratoconus","volume":"25","author":"Coskunseven","year":"2009","journal-title":"J Refract Surg"},{"issue":"7","key":"10.1016\/j.ajo.2011.04.033_bib6","first-page":"S720","article-title":"A randomized controlled trial of corneal collagen cross-linking in progressive keratoconus: preliminary results","volume":"24","author":"Wittig-Silva","year":"2008","journal-title":"J Refract Surg"},{"issue":"4","key":"10.1016\/j.ajo.2011.04.033_bib7","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1016\/j.ajo.2009.10.021","article-title":"Long-term results of riboflavin ultraviolet a corneal collagen cross-linking for keratoconus in Italy: the Siena eye cross study","volume":"149","author":"Caporossi","year":"2010","journal-title":"Am J Ophthalmol"},{"issue":"2","key":"10.1016\/j.ajo.2011.04.033_bib8","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1097\/ICO.0b013e3181a818ab","article-title":"Conductive keratoplasty followed by collagen cross-linking with riboflavin-UV-A in patients with keratoconus","volume":"29","author":"Kymionis","year":"2010","journal-title":"Cornea"},{"issue":"9","key":"10.1016\/j.ajo.2011.04.033_bib9","first-page":"S807","article-title":"Simultaneous topography-guided PRK followed by corneal collagen cross-linking for keratoconus","volume":"25","author":"Kymionis","year":"2009","journal-title":"J Refract Surg"},{"issue":"10","key":"10.1016\/j.ajo.2011.04.033_bib10","doi-asserted-by":"crossref","first-page":"1258","DOI":"10.1001\/archophthalmol.2009.205","article-title":"Intraoperative and postoperative effects of corneal collagen cross-linking on progressive keratoconus","volume":"127","author":"Vinciguerra","year":"2009","journal-title":"Arch Ophthalmol"},{"issue":"5","key":"10.1016\/j.ajo.2011.04.033_bib11","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1001\/archopht.1990.01070070051034","article-title":"Wound healing after excimer laser keratomileusis (photorefractive keratectomy) in monkeys","volume":"108","author":"Fantes","year":"1990","journal-title":"Arch Ophthalmol"},{"key":"10.1016\/j.ajo.2011.04.033_bib12","first-page":"411","article-title":"Analysis of the keratocyte apoptosis, keratocyte proliferation, and myofibroblast transformation responses after photorefractive keratectomy and laser in situ keratomileusis","volume":"100","author":"Wilson","year":"2002","journal-title":"Trans Am Ophthalmol Soc"},{"issue":"5","key":"10.1016\/j.ajo.2011.04.033_bib13","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1016\/S0002-9394(02)02220-1","article-title":"Riboflavin\/ultraviolet-a-induced collagen crosslinking for the treatment of keratoconus","volume":"135","author":"Wollensak","year":"2003","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.ajo.2011.04.033_bib14","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/j.jcrs.2004.04.044","article-title":"Transepithelial phototherapeutic keratectomy\/photorefractive keratectomy with adjunctive mitomycin-C for complicated LASIK flaps","volume":"31","author":"Muller","year":"2005","journal-title":"J Cataract Refract Surg"},{"key":"10.1016\/j.ajo.2011.04.033_bib15","doi-asserted-by":"crossref","first-page":"1603","DOI":"10.1016\/j.jcrs.2005.01.014","article-title":"Combination of transepithelial phototherapeutic keratectomy and autologous serum eyedrops for treatment of recurrent corneal erosions","volume":"31","author":"Holzer","year":"2005","journal-title":"J Cataract Refract Surg"},{"issue":"5","key":"10.1016\/j.ajo.2011.04.033_bib16","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1016\/j.ajo.2008.11.017","article-title":"One-year follow-up of corneal confocal microscopy after corneal cross-linking in patients with post laser in situ keratomileusis ectasia and keratoconus","volume":"147","author":"Kymionis","year":"2009","journal-title":"Am J Ophthalmol"},{"issue":"4","key":"10.1016\/j.ajo.2011.04.033_bib17","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1097\/ICO.0b013e318030df5a","article-title":"Treatment of progressive keratoconus by riboflavin-UVA-induced cross-linking of corneal collagen: ultrastructural analysis by Heidelberg Retinal Tomograph II in vivo confocal microscopy in humans","volume":"26","author":"Mazzotta","year":"2007","journal-title":"Cornea"},{"issue":"3","key":"10.1016\/j.ajo.2011.04.033_bib18","first-page":"487","article-title":"Confocal microscopic characterization of wound repair after photorefractive keratectomy","volume":"39","author":"M\u00f8ller-Pedersen","year":"1998","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"3","key":"10.1016\/j.ajo.2011.04.033_bib19","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1016\/j.ophtha.2008.09.048","article-title":"Refractive, topographic, tomographic, and aberrometric analysis of keratoconic eyes undergoing corneal cross-linking","volume":"116","author":"Vinciguerra","year":"2009","journal-title":"Ophthalmology"}],"container-title":["American Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002939411003734?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002939411003734?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T13:04:00Z","timestamp":1757595840000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002939411003734"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,11]]},"references-count":19,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2011,11]]}},"alternative-id":["S0002939411003734"],"URL":"https:\/\/doi.org\/10.1016\/j.ajo.2011.04.033","relation":{},"ISSN":["0002-9394"],"issn-type":[{"value":"0002-9394","type":"print"}],"subject":[],"published":{"date-parts":[[2011,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Simultaneous Topography-Guided Photorefractive Keratectomy Followed by Corneal Collagen Cross-linking for Keratoconus","name":"articletitle","label":"Article Title"},{"value":"American Journal of Ophthalmology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajo.2011.04.033","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2011 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}