{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T03:50:51Z","timestamp":1793332251453,"version":"4.5.0"},"reference-count":21,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2014,6,1]],"date-time":"2014-06-01T00:00:00Z","timestamp":1401580800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2014,6,1]],"date-time":"2014-06-01T00:00:00Z","timestamp":1401580800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["ajo.com","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["American Journal of Ophthalmology"],"published-print":{"date-parts":[[2014,6]]},"DOI":"10.1016\/j.ajo.2014.02.044","type":"journal-article","created":{"date-parts":[[2014,2,26]],"date-time":"2014-02-26T06:03:49Z","timestamp":1393394629000},"page":"1299-1305","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":83,"title":["Reduced Risk of Compressive Optic Neuropathy Using Orbital Radiotherapy in Patients With Active Thyroid Eye Disease"],"prefix":"10.1016","volume":"157","author":[{"given":"Pari N.","family":"Shams","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roy","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tom","family":"Pickles","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jack","family":"Rootman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter J.","family":"Dolman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.ajo.2014.02.044_bib1","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/j.beem.2011.11.007","article-title":"Evaluating Graves' orbitopathy","volume":"26","author":"Dolman","year":"2012","journal-title":"Best Pract Res Clin Endocrinol Metab"},{"issue":"10","key":"10.1016\/j.ajo.2014.02.044_bib2","doi-asserted-by":"crossref","first-page":"994","DOI":"10.1056\/NEJMcp0806317","article-title":"Clinical practice. Graves' ophthalmopathy","volume":"360","author":"Bartalena","year":"2009","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ajo.2014.02.044_bib3","first-page":"58","article-title":"Diseases of the orbit. Acute purulent keratitis in exophthalmic goitre treated by repeated tarsorrhaphy, resection of cervical sympathetic and x-rays; retention of vision in one eye","volume":"33","author":"Juler","year":"1913","journal-title":"Trans Ophthalmol Soc UK"},{"issue":"2","key":"10.1016\/j.ajo.2014.02.044_bib4","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1097\/WNO.0b013e318255d7c7","article-title":"Orbital radiation therapy for thyroid eye disease","volume":"32","author":"Kazim","year":"2012","journal-title":"J Neuroophthalmol"},{"issue":"5","key":"10.1016\/j.ajo.2014.02.044_bib5","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1097\/ICU.0b013e3283560b2b","article-title":"Orbital radiotherapy for thyroid eye disease","volume":"23","author":"Dolman","year":"2012","journal-title":"Curr Opin Ophthalmol"},{"issue":"1","key":"10.1016\/j.ajo.2014.02.044_bib6","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1111\/j.1365-2265.1987.tb00836.x","article-title":"Orbital cobalt irradiation combined with retrobulbar or systemic corticosteroids for Graves' ophthalmopathy: a comparative study","volume":"27","author":"Marcocci","year":"1987","journal-title":"Clin Endocrinol (Oxf)"},{"issue":"3","key":"10.1016\/j.ajo.2014.02.044_bib7","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1089\/105072502753600223","article-title":"Orbital radiotherapy for Graves' ophthalmopathy","volume":"12","author":"Bartalena","year":"2002","journal-title":"Thyroid"},{"issue":"6","key":"10.1016\/j.ajo.2014.02.044_bib8","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1097\/00130404-200311000-00007","article-title":"Radiotherapy for moderate-to-severe Graves' ophthalmopathy: improved outcomes with early treatment","volume":"9","author":"Alpert","year":"2003","journal-title":"Cancer J"},{"issue":"2","key":"10.1016\/j.ajo.2014.02.044_bib9","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1016\/j.ophtha.2007.10.028","article-title":"Orbital radiation for Graves ophthalmopathy: a report by the American Academy of Ophthalmology","volume":"115","author":"Bradley","year":"2008","journal-title":"Ophthalmology"},{"key":"10.1016\/j.ajo.2014.02.044_bib10","first-page":"CD007114","article-title":"Orbital radiotherapy for adult thyroid eye disease","volume":"7","author":"Rajendram","year":"2012","journal-title":"Cochrane Database Syst Rev"},{"issue":"9","key":"10.1016\/j.ajo.2014.02.044_bib11","doi-asserted-by":"crossref","first-page":"1523","DOI":"10.1016\/S0161-6420(01)00632-7","article-title":"A prospective, randomized, double-blind, placebo-controlled study of orbital radiotherapy for Graves' ophthalmopathy","volume":"108","author":"Gorman","year":"2001","journal-title":"Ophthalmology"},{"issue":"8877","key":"10.1016\/j.ajo.2014.02.044_bib12","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1016\/0140-6736(93)92001-A","article-title":"Randomized double-blind trial of prednisone versus radiotherapy in Graves' ophthalmopathy","volume":"342","author":"Prummel","year":"1993","journal-title":"Lancet"},{"issue":"1","key":"10.1016\/j.ajo.2014.02.044_bib13","first-page":"102","article-title":"Low- versus high-dose radiotherapy for Graves' ophthalmopathy: a randomized, single blind trial","volume":"85","author":"Kahaly","year":"2000","journal-title":"J Clin Endocrinol Metab"},{"issue":"9214","key":"10.1016\/j.ajo.2014.02.044_bib14","doi-asserted-by":"crossref","first-page":"1505","DOI":"10.1016\/S0140-6736(00)02165-6","article-title":"Radiotherapy for Graves' orbitopathy: randomised placebo-controlled study","volume":"355","author":"Mourits","year":"2000","journal-title":"Lancet"},{"issue":"1","key":"10.1016\/j.ajo.2014.02.044_bib15","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1210\/jc.2003-030809","article-title":"A randomized controlled trial of orbital radiotherapy versus sham irradiation in patients with mild Graves' ophthalmopathy","volume":"89","author":"Prummel","year":"2004","journal-title":"J Clin Endocrinol Metab"},{"issue":"5","key":"10.1016\/j.ajo.2014.02.044_bib16","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1097\/01.iop.0000235499.34867.85","article-title":"VISA classification for Graves orbitopathy","volume":"22","author":"Dolman","year":"2006","journal-title":"Ophthal Plast Reconstr Surg"},{"issue":"2","key":"10.1016\/j.ajo.2014.02.044_bib17","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1016\/j.ophtha.2011.07.011","article-title":"Reliability of estimating ductions in thyroid eye disease: an International Thyroid Eye Disease Society multicenter study","volume":"119","author":"Dolman","year":"2012","journal-title":"Ophthalmology"},{"issue":"10","key":"10.1016\/j.ajo.2014.02.044_bib18","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1007\/BF03347943","article-title":"Orbital radiotherapy combined with high dose\u00a0systemic glucocorticoids for Graves' ophthalmopathy is\u00a0more effective than radiotherapy alone: results of a prospective randomized study","volume":"14","author":"Marcocci","year":"1991","journal-title":"J Endocrinol Invest"},{"issue":"6","key":"10.1016\/j.ajo.2014.02.044_bib19","doi-asserted-by":"crossref","first-page":"1139","DOI":"10.1210\/jcem-56-6-1139","article-title":"Orbital cobalt irradiation combined with systemic corticosteroids for Graves' ophthalmopathy: comparison with systemic corticosteroids alone","volume":"56","author":"Bartalena","year":"1983","journal-title":"J Clin Endocrinol Metab"},{"issue":"5","key":"10.1016\/j.ajo.2014.02.044_bib20","first-page":"322","article-title":"Combined orbital irradiation and systemic steroids compared with systemic steroids alone in the management of moderate-to-severe Graves' ophthalmopathy: a preliminary study","volume":"11","author":"Ng","year":"2005","journal-title":"Hong Kong Med J"},{"issue":"8","key":"10.1016\/j.ajo.2014.02.044_bib21","doi-asserted-by":"crossref","first-page":"1557","DOI":"10.1016\/j.ophtha.2003.12.054","article-title":"Orbital irradiation for Graves' ophthalmopathy: Is it safe? A long-term follow-up study","volume":"111","author":"Wakelkamp","year":"2004","journal-title":"Ophthalmology"}],"container-title":["American Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002939414001275?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002939414001275?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T13:10:14Z","timestamp":1757596214000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002939414001275"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,6]]},"references-count":21,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2014,6]]}},"alternative-id":["S0002939414001275"],"URL":"https:\/\/doi.org\/10.1016\/j.ajo.2014.02.044","relation":{},"ISSN":["0002-9394"],"issn-type":[{"value":"0002-9394","type":"print"}],"subject":[],"published":{"date-parts":[[2014,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Reduced Risk of Compressive Optic Neuropathy Using Orbital Radiotherapy in Patients With Active Thyroid Eye Disease","name":"articletitle","label":"Article Title"},{"value":"American Journal of Ophthalmology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajo.2014.02.044","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}