{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T06:10:23Z","timestamp":1790835023949,"version":"4.1.0"},"reference-count":31,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,9,1]],"date-time":"2020-09-01T00:00:00Z","timestamp":1598918400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,9,1]],"date-time":"2020-09-01T00:00:00Z","timestamp":1598918400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100001818","name":"Research to Prevent Blindness","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100001818","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["ajo.com","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["American Journal of Ophthalmology"],"published-print":{"date-parts":[[2020,9]]},"DOI":"10.1016\/j.ajo.2020.04.022","type":"journal-article","created":{"date-parts":[[2020,4,28]],"date-time":"2020-04-28T11:20:19Z","timestamp":1588072819000},"page":"104-113","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":48,"special_numbering":"C","title":["Choroidal Anatomic Alterations After Photodynamic Therapy for Chronic Central Serous Chorioretinopathy: A Multicenter Study"],"prefix":"10.1016","volume":"217","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1984-0555","authenticated-orcid":false,"given":"Claudio","family":"Iovino","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8110-9988","authenticated-orcid":false,"given":"Adrian","family":"Au","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1772-3558","authenticated-orcid":false,"given":"Jay","family":"Chhablani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deepika C.","family":"Parameswarappa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammed Abdul","family":"Rasheed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4253-1929","authenticated-orcid":false,"given":"Gilda","family":"Cennamo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giovanni","family":"Cennamo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniela","family":"Montorio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allen C.","family":"Ho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3649-4746","authenticated-orcid":false,"given":"David","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3292-9581","authenticated-orcid":false,"given":"Giuseppe","family":"Querques","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2815-5031","authenticated-orcid":false,"given":"Enrico","family":"Borrelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2891-2012","authenticated-orcid":false,"given":"Riccardo","family":"Sacconi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7357-4166","authenticated-orcid":false,"given":"Francesco","family":"Pichi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth","family":"Woodstock","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Srinivas R.","family":"Sadda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9213-5575","authenticated-orcid":false,"given":"Giulia","family":"Corradetti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4625-6795","authenticated-orcid":false,"given":"Camiel J.F.","family":"Boon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elon H.C.","family":"van Dijk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anat","family":"Loewenstein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1147-444X","authenticated-orcid":false,"given":"Dinah","family":"Zur","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sugiura","family":"Yoshimi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7888-9773","authenticated-orcid":false,"given":"K. Bailey","family":"Freund","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Enrico","family":"Peiretti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Sarraf","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.ajo.2020.04.022_bib1","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/S0002-9394(14)70531-8","article-title":"Choroidal capillary and venous congestion in central serous chorioretinopathy","volume":"121","author":"Pr\u00fcnte","year":"1996","journal-title":"Am J Ophthalmol"},{"issue":"3","key":"10.1016\/j.ajo.2020.04.022_bib2","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1097\/00006982-199616030-00004","article-title":"Indocyanine green videoangiography of older patients with central serous chorioretinopathy","volume":"16","author":"Spaide","year":"1996","journal-title":"Retina"},{"issue":"4","key":"10.1016\/j.ajo.2020.04.022_bib3","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1007\/BF00169099","article-title":"Long-term follow-up of central serous retinopathy in 150 patients","volume":"81","author":"Castro-Correia","year":"1992","journal-title":"Doc Ophthalmol"},{"key":"10.1016\/j.ajo.2020.04.022_bib4","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/S0161-6420(92)32010-X","article-title":"Central serous chorioretinopathy occurring in patients 60 years of age and older","volume":"99","author":"Schatz","year":"1992","journal-title":"Ophthalmology"},{"issue":"12","key":"10.1016\/j.ajo.2020.04.022_bib5","doi-asserted-by":"crossref","first-page":"1871","DOI":"10.1038\/s41433-019-0505-0","article-title":"Retinal pigment epithelium apertures as a late complication of longstanding serous pigment epithelium detachments in chronic central serous chorioretinopathy","volume":"33","author":"Iovino","year":"2019","journal-title":"Eye (Lond)"},{"issue":"10","key":"10.1016\/j.ajo.2020.04.022_bib6","doi-asserted-by":"crossref","first-page":"1547","DOI":"10.1016\/j.ophtha.2018.04.021","article-title":"Half-dose photodynamic therapy versus high-density subthreshold micropulse laser treatment in patients with chronic central serous chorioretinopathy: the PLACE trial","volume":"125","author":"van Dijk","year":"2018","journal-title":"Ophthalmology"},{"key":"10.1016\/j.ajo.2020.04.022_bib7","doi-asserted-by":"crossref","first-page":"100770","DOI":"10.1016\/j.preteyeres.2019.07.003","article-title":"Central serous chorioretinopathy: towards an evidence-based treatment guideline","volume":"73","author":"van Rijssen","year":"2019","journal-title":"Prog Retin Eye Res"},{"issue":"12","key":"10.1016\/j.ajo.2020.04.022_bib8","doi-asserted-by":"crossref","first-page":"1453","DOI":"10.1136\/bjo.87.12.1453","article-title":"Choroidal vascular remodelling in central serous chorioretinopathy after indocyanine green guided photodynamic therapy with verteporfin: a novel treatment at the primary disease level","volume":"87","author":"Chan","year":"2003","journal-title":"Br J Ophthalmol"},{"issue":"6","key":"10.1016\/j.ajo.2020.04.022_bib9","first-page":"835","article-title":"Histopathological changes following photodynamic therapy in human eyes","volume":"120","author":"Schmidt-Erfurth","year":"2002","journal-title":"Arch Ophthalmol"},{"issue":"4","key":"10.1016\/j.ajo.2020.04.022_bib10","doi-asserted-by":"crossref","first-page":"644","DOI":"10.1016\/j.ajo.2015.01.006","article-title":"Change of regional choroid thickness after reduced-fluence photodynamic therapy for chronic central serous chorioretinopathy","volume":"159","author":"Manabe","year":"2015","journal-title":"Am J Ophthalmol"},{"issue":"4","key":"10.1016\/j.ajo.2020.04.022_bib11","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1136\/bjophthalmol-2016-308921","article-title":"Structural analyses of choroid after half-dose verteporfin photodynamic therapy for central serous chorioretinopathy","volume":"101","author":"Izumi","year":"2017","journal-title":"Br J Ophthalmol"},{"issue":"3","key":"10.1016\/j.ajo.2020.04.022_bib12","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1159\/000456676","article-title":"Effect of photodynamic therapy on optical coherence tomography angiography in eyes with chronic central serous chorioretinopathy","volume":"237","author":"Xu","year":"2017","journal-title":"Ophthalmologica"},{"issue":"5","key":"10.1016\/j.ajo.2020.04.022_bib13","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1007\/s00417-018-04226-6","article-title":"Vascular and structural alterations of the choroid evaluated by optical coherence tomography angiography and optical coherence tomography after half-fluence photodynamic therapy in chronic central serous chorioretinopathy","volume":"257","author":"Demirel","year":"2019","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"issue":"3","key":"10.1016\/j.ajo.2020.04.022_bib14","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1016\/j.survophthal.2018.11.002","article-title":"Choroidal imaging biomarkers","volume":"64","author":"Singh","year":"2019","journal-title":"Surv Ophthalmol"},{"issue":"2","key":"10.1016\/j.ajo.2020.04.022_bib15","doi-asserted-by":"crossref","first-page":"595","DOI":"10.3390\/jcm9020595","article-title":"Choroidal vascularity index: an in-depth analysis of this novel optical coherence tomography parameter","volume":"9","author":"Iovino","year":"2020","journal-title":"J Clin Med"},{"key":"10.1016\/j.ajo.2020.04.022_bib16","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1016\/j.compmedimag.2015.09.008","article-title":"Automated estimation of choroidal thickness distribution and volume based on OCT images of posterior visual section","volume":"46","author":"Vupparaboina","year":"2015","journal-title":"Comput Med Imaging Graph"},{"issue":"12","key":"10.1016\/j.ajo.2020.04.022_bib17","doi-asserted-by":"crossref","first-page":"1785","DOI":"10.4103\/ijo.IJO_663_18","article-title":"Qualitative comparison of choroidal vascularity measurement algorithms","volume":"66","author":"Rasheed","year":"2018","journal-title":"Indian J Ophthalmol"},{"issue":"3","key":"10.1016\/j.ajo.2020.04.022_bib18","doi-asserted-by":"crossref","first-page":"191","DOI":"10.3928\/23258160-20180221-07","article-title":"Choroidal vascularity index in retinitis pigmentosa: an OCT study","volume":"49","author":"Tan","year":"2018","journal-title":"Ophthalmic Surg Lasers Imaging Retin"},{"issue":"8","key":"10.1016\/j.ajo.2020.04.022_bib19","doi-asserted-by":"crossref","first-page":"e770","DOI":"10.1111\/aos.13442","article-title":"Influence of scanning area on choroidal vascularity index measurement using optical coherence tomography","volume":"95","author":"Agrawal","year":"2017","journal-title":"Acta Ophthalmol"},{"issue":"15","key":"10.1016\/j.ajo.2020.04.022_bib20","doi-asserted-by":"crossref","first-page":"5000","DOI":"10.1167\/iovs.19-27300","article-title":"Evaluation of the choroid in eyes with retinitis pigmentosa and cystoid macular edema","volume":"60","author":"Iovino","year":"2019","journal-title":"Investig Opthalmology Vis Sci"},{"issue":"5","key":"10.1016\/j.ajo.2020.04.022_bib21","doi-asserted-by":"crossref","first-page":"960","DOI":"10.1097\/IAE.0000000000002459","article-title":"Choroidal vascularity index quantification in geographic atrophy using binarization of enhanced-depth imaging optical coherence tomographic scans","volume":"40","author":"Giannaccare","year":"2020","journal-title":"Retina"},{"key":"10.1016\/j.ajo.2020.04.022_bib22","article-title":"Use of choroidal vascularity index for choroidal structural evaluation in central serous chorioretinopathy with choroidal neovascularization","author":"Kim","year":"2019","journal-title":"Retina"},{"issue":"12","key":"10.1016\/j.ajo.2020.04.022_bib23","doi-asserted-by":"crossref","first-page":"2395","DOI":"10.1097\/IAE.0000000000001879","article-title":"Choroidal structural changes and vascularity index in stargardt disease on swept source optical coherence tomography","volume":"38","author":"Ratra","year":"2018","journal-title":"Retina"},{"issue":"1","key":"10.1016\/j.ajo.2020.04.022_bib24","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1038\/s41433-018-0158-4","article-title":"Pachychoroid disease","volume":"33","author":"Cheung","year":"2019","journal-title":"Eye (Lond)"},{"key":"10.1016\/j.ajo.2020.04.022_bib25","doi-asserted-by":"crossref","first-page":"2468","DOI":"10.3390\/ijms18112468","article-title":"Short-term choriocapillaris changes in patients with central serous chorioretinopathy after half-dose photodynamic therapy","volume":"18","author":"Nassisi","year":"2017","journal-title":"Int J Mol Sci"},{"issue":"7","key":"10.1016\/j.ajo.2020.04.022_bib26","doi-asserted-by":"crossref","first-page":"1365","DOI":"10.1007\/s00417-019-04318-x","article-title":"Optical coherent tomographic angiographic pattern of the deep choroidal layer and choriocapillaris after photodynamic therapy for central serous chorioretinopathy","volume":"257","author":"Chan","year":"2019","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"issue":"8","key":"10.1016\/j.ajo.2020.04.022_bib27","doi-asserted-by":"crossref","first-page":"1526","DOI":"10.1097\/IAE.0000000000001750","article-title":"Anti\u2013vascular endothelial growth factor therapy versus photodynamic therapy in the treatment of choroidal neovascularization secondary to central serous chorioretinopathy","volume":"38","author":"Peiretti","year":"2018","journal-title":"Retina"},{"issue":"10","key":"10.1016\/j.ajo.2020.04.022_bib28","doi-asserted-by":"crossref","first-page":"2155","DOI":"10.1007\/s00417-019-04426-8","article-title":"Comparing effects of photodynamic therapy in central serous chorioretinopathy: full-dose versus half-dose versus half-dose-half-fluence","volume":"257","author":"Park","year":"2019","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"issue":"2","key":"10.1016\/j.ajo.2020.04.022_bib29","doi-asserted-by":"crossref","first-page":"e26","DOI":"10.3928\/23258160-20190129-15","article-title":"Choroidal vascularity index using swept-source and spectral-domain optical coherence tomography: a comparative study","volume":"50","author":"Agrawal","year":"2019","journal-title":"Ophthalmic Surg Lasers Imaging Retin"},{"issue":"8","key":"10.1016\/j.ajo.2020.04.022_bib30","doi-asserted-by":"crossref","first-page":"738","DOI":"10.1111\/j.1755-3768.2011.02157.x","article-title":"Choroidal thickness following extrafoveal photodynamic treatment with verteporfin in patients with central serous chorioretinopathy","volume":"90","author":"Pryds","year":"2012","journal-title":"Acta Ophthalmol"},{"issue":"10","key":"10.1016\/j.ajo.2020.04.022_bib31","doi-asserted-by":"crossref","first-page":"2029","DOI":"10.1007\/s00417-017-3720-z","article-title":"Photodynamic therapy in chronic central serous chorioretinopathy with subretinal fluid outside the fovea","volume":"255","author":"van Dijk","year":"2017","journal-title":"Graefes Arch Clin Exp Ophthalmol"}],"container-title":["American Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002939420301902?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002939420301902?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T13:42:48Z","timestamp":1757598168000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002939420301902"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,9]]},"references-count":31,"alternative-id":["S0002939420301902"],"URL":"https:\/\/doi.org\/10.1016\/j.ajo.2020.04.022","relation":{},"ISSN":["0002-9394"],"issn-type":[{"value":"0002-9394","type":"print"}],"subject":[],"published":{"date-parts":[[2020,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Choroidal Anatomic Alterations After Photodynamic Therapy for Chronic Central Serous Chorioretinopathy: A Multicenter Study","name":"articletitle","label":"Article Title"},{"value":"American Journal of Ophthalmology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajo.2020.04.022","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}