{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T21:06:49Z","timestamp":1792530409849,"version":"4.5.0"},"reference-count":34,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003621","name":"Ministry of Science, ICT and Future Planning","doi-asserted-by":"publisher","award":["2020R1F1A1072264"],"award-info":[{"award-number":["2020R1F1A1072264"]}],"id":[{"id":"10.13039\/501100003621","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["ajo.com","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["American Journal of Ophthalmology"],"published-print":{"date-parts":[[2024,1]]},"DOI":"10.1016\/j.ajo.2023.08.015","type":"journal-article","created":{"date-parts":[[2023,8,26]],"date-time":"2023-08-26T01:47:15Z","timestamp":1693014435000},"page":"76-83","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Increased Risk of Optic Neuritis in Patients With Fibromyalgia: Nationwide Population-Based Cohort Study in South Korea"],"prefix":"10.1016","volume":"257","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1634-7482","authenticated-orcid":false,"given":"Hyung Rae","family":"Cho","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0716-4166","authenticated-orcid":false,"given":"Geung Kyu","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7540-7129","authenticated-orcid":false,"given":"Ju-Yeun","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"5","key":"10.1016\/j.ajo.2023.08.015_bib0001","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1002\/acr.20140","article-title":"The American College of Rheumatology preliminary diagnostic criteria for fibromyalgia and measurement of symptom severity","volume":"62","author":"Wolfe","year":"2010","journal-title":"Arthritis Care Res (Hoboken)"},{"key":"10.1016\/j.ajo.2023.08.015_bib0002","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/j.neuroscience.2016.06.006","article-title":"Neurobiology of fibromyalgia and chronic widespread pain","volume":"338","author":"Sluka","year":"2016","journal-title":"Neuroscience"},{"issue":"1","key":"10.1016\/j.ajo.2023.08.015_bib0003","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1097\/j.pain.0000000000000707","article-title":"Towards a neurophysiological signature for fibromyalgia","volume":"158","author":"Lopez-Sola","year":"2017","journal-title":"Pain"},{"issue":"1","key":"10.1016\/j.ajo.2023.08.015_bib0004","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.autrev.2017.11.007","article-title":"Are the ACR 2010 diagnostic criteria for fibromyalgia better than the 1990 criteria?","volume":"17","author":"Sarzi-Puttini","year":"2018","journal-title":"Autoimmun Rev"},{"issue":"20","key":"10.1016\/j.ajo.2023.08.015_bib0005","doi-asserted-by":"crossref","first-page":"5164","DOI":"10.3390\/ijms20205164","article-title":"Neuroimmunology: what role for autoimmunity, neuroinflammation, and small fiber neuropathy in fibromyalgia, chronic fatigue syndrome, and adverse events after human papillomavirus vaccination?","volume":"20","author":"Ryabkova","year":"2019","journal-title":"Int J Mol Sci"},{"issue":"Suppl 123","key":"10.1016\/j.ajo.2023.08.015_bib0006","first-page":"3","article-title":"One year in review 2020: fibromyalgia","volume":"38","author":"Bazzichi","year":"2020","journal-title":"Clin Exp Rheumatol"},{"issue":"5","key":"10.1016\/j.ajo.2023.08.015_bib0007","doi-asserted-by":"crossref","DOI":"10.7326\/AITC202003030","article-title":"Fibromyalgia","volume":"172","author":"Bair","year":"2020","journal-title":"Ann Intern Med"},{"issue":"5","key":"10.1016\/j.ajo.2023.08.015_bib0008","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1016\/j.mayocp.2015.03.014","article-title":"Fibromyalgia and related conditions","volume":"90","author":"Clauw","year":"2015","journal-title":"Mayo Clin Proc"},{"issue":"1","key":"10.1016\/j.ajo.2023.08.015_bib0009","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.survophthal.2020.05.006","article-title":"Fibromyalgia syndrome and the eye\u2014a review","volume":"66","author":"Zdebik","year":"2021","journal-title":"Surv Ophthalmol"},{"issue":"4","key":"10.1016\/j.ajo.2023.08.015_bib0010","doi-asserted-by":"crossref","first-page":"e2607","DOI":"10.1097\/MD.0000000000002607","article-title":"Dry eye syndrome risks in patients with fibromyalgia: a national retrospective cohort study","volume":"95","author":"Chen","year":"2016","journal-title":"Medicine (Baltimore)"},{"issue":"6","key":"10.1016\/j.ajo.2023.08.015_bib0011","doi-asserted-by":"crossref","first-page":"862","DOI":"10.1097\/ICO.0b013e318285c912","article-title":"Dry eye in patients with fibromyalgia and its relevance to functional and emotional status","volume":"32","author":"Turkyilmaz","year":"2013","journal-title":"Cornea"},{"issue":"11","key":"10.1016\/j.ajo.2023.08.015_bib0012","doi-asserted-by":"crossref","first-page":"1835","DOI":"10.1007\/s00296-017-3794-2","article-title":"Association between objective signs and subjective symptoms of dry eye disease in patients with systemic sclerosis","volume":"37","author":"Rentka","year":"2017","journal-title":"Rheumatol Int"},{"issue":"9","key":"10.1016\/j.ajo.2023.08.015_bib0013","doi-asserted-by":"crossref","first-page":"4129","DOI":"10.1167\/iovs.08-3083","article-title":"Decreased corneal sensitivity and tear production in fibromyalgia","volume":"50","author":"Gallar","year":"2009","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"4","key":"10.1016\/j.ajo.2023.08.015_bib0014","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1038\/eye.2017.275","article-title":"Corneal sensitivity and subjective complaints of ocular pain in patients with fibromyalgia","volume":"32","author":"Aykut","year":"2018","journal-title":"Eye (Lond)"},{"key":"10.1016\/j.ajo.2023.08.015_bib0015","doi-asserted-by":"crossref","DOI":"10.1177\/1744806916666284","article-title":"Ganglioside GM3 synthase depletion reverses neuropathic pain and small fiber neuropathy in diet-induced diabetic mice","volume":"12","author":"Menichella","year":"2016","journal-title":"Mol Pain"},{"key":"10.1016\/j.ajo.2023.08.015_bib0016","doi-asserted-by":"crossref","DOI":"10.3389\/fnins.2020.572965","article-title":"Gangliosides in the brain: physiology, pathophysiology and therapeutic applications","volume":"14","author":"Sipione","year":"2020","journal-title":"Front Neurosci"},{"issue":"9","key":"10.1016\/j.ajo.2023.08.015_bib0017","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0161574","article-title":"Fibromyalgia is correlated with retinal nerve fiber layer thinning","volume":"11","author":"Garcia-Martin","year":"2016","journal-title":"PLoS One"},{"issue":"3","key":"10.1016\/j.ajo.2023.08.015_bib0018","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1016\/j.ophtha.2019.09.032","article-title":"Population-based incidence of pediatric and adult optic neuritis and the risk of multiple sclerosis","volume":"127","author":"Lee","year":"2020","journal-title":"Ophthalmology"},{"issue":"3","key":"10.1016\/j.ajo.2023.08.015_bib0019","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1097\/01.rhu.0000221817.46231.18","article-title":"The incidence of fibromyalgia and its associated comorbidities: a population-based retrospective cohort study based on International Classification of Diseases, 9th Revision codes","volume":"12","author":"Weir","year":"2006","journal-title":"J Clin Rheumatol"},{"issue":"15","key":"10.1016\/j.ajo.2023.08.015_bib0020","doi-asserted-by":"crossref","first-page":"1649","DOI":"10.1001\/archinte.166.15.1649","article-title":"Chronic widespread pain and its comorbidities: a population-based study","volume":"166","author":"Kato","year":"2006","journal-title":"Arch Intern Med"},{"key":"10.1016\/j.ajo.2023.08.015_bib0021","doi-asserted-by":"crossref","DOI":"10.1016\/j.jpsychores.2022.110745","article-title":"The risk factors for self-reported fibromyalgia with and without multiple somatic symptoms: The Lifelines cohort study","volume":"155","author":"Creed","year":"2022","journal-title":"J Psychosom Res"},{"issue":"8","key":"10.1016\/j.ajo.2023.08.015_bib0022","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1097\/NEN.0b013e31829c7370","article-title":"Calcium influx and calpain activation mediate preclinical retinal neurodegeneration in autoimmune optic neuritis","volume":"72","author":"Hoffmann","year":"2013","journal-title":"J Neuropathol Exp Neurol"},{"issue":"8","key":"10.1016\/j.ajo.2023.08.015_bib0023","doi-asserted-by":"crossref","DOI":"10.1016\/j.autrev.2022.103129","article-title":"Clinical overlap between fibromyalgia and myalgic encephalomyelitis. A systematic review and meta-analysis","volume":"21","author":"Ramirez-Morales","year":"2022","journal-title":"Autoimmun Rev"},{"key":"10.1016\/j.ajo.2023.08.015_bib0024","doi-asserted-by":"crossref","first-page":"515","DOI":"10.2147\/JPR.S128508","article-title":"Evidence of both systemic inflammation and neuroinflammation in fibromyalgia patients, as assessed by a multiplex protein panel applied to the cerebrospinal fluid and to plasma","volume":"10","author":"Backryd","year":"2017","journal-title":"J Pain Res"},{"key":"10.1016\/j.ajo.2023.08.015_bib0025","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/j.bbi.2018.09.018","article-title":"Brain glial activation in fibromyalgia\u2014a multi-site positron emission tomography investigation","volume":"75","author":"Albrecht","year":"2019","journal-title":"Brain Behav Immun"},{"issue":"Pt 1","key":"10.1016\/j.ajo.2023.08.015_bib0026","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1093\/brain\/aws284","article-title":"The neural androgen receptor: a therapeutic target for myelin repair in chronic demyelination","volume":"136","author":"Hussain","year":"2013","journal-title":"Brain"},{"key":"10.1016\/j.ajo.2023.08.015_bib0027","doi-asserted-by":"crossref","first-page":"1567","DOI":"10.3389\/fimmu.2020.01567","article-title":"The effects of androgens on T cells: clues to female predominance in autoimmune liver diseases?","volume":"11","author":"Henze","year":"2020","journal-title":"Front Immunol"},{"issue":"1","key":"10.1016\/j.ajo.2023.08.015_bib0028","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1080\/13685538.2021.2023493","article-title":"Correlates of testosterone change as men age","volume":"25","author":"Kanabar","year":"2022","journal-title":"Aging Male"},{"issue":"16","key":"10.1016\/j.ajo.2023.08.015_bib0029","doi-asserted-by":"crossref","first-page":"8867","DOI":"10.1073\/pnas.96.16.8867","article-title":"The antioxidant neuroprotective effects of estrogens and phenolic compounds are independent from their estrogenic properties","volume":"96","author":"Moosmann","year":"1999","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"10","key":"10.1016\/j.ajo.2023.08.015_bib0030","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1038\/nri.2016.90","article-title":"Sex differences in immune responses","volume":"16","author":"Klein","year":"2016","journal-title":"Nat Rev Immunol"},{"issue":"5","key":"10.1016\/j.ajo.2023.08.015_bib0031","doi-asserted-by":"crossref","first-page":"1344","DOI":"10.1002\/art.10209","article-title":"Impaired growth hormone secretion in fibromyalgia patients: evidence for augmented hypothalamic somatostatin tone","volume":"46","author":"Paiva","year":"2002","journal-title":"Arthritis Rheum"},{"issue":"4","key":"10.1016\/j.ajo.2023.08.015_bib0032","first-page":"1672","article-title":"Decreased nocturnal levels of prolactin and growth hormone in women with fibromyalgia","volume":"86","author":"Landis","year":"2001","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.ajo.2023.08.015_bib0033","doi-asserted-by":"crossref","first-page":"777","DOI":"10.3389\/fendo.2019.00777","article-title":"Growth hormone and insulin-like growth factor action in reproductive tissues","volume":"10","author":"Ipsa","year":"2019","journal-title":"Front Endocrinol (Lausanne)"},{"issue":"5","key":"10.1016\/j.ajo.2023.08.015_bib0034","doi-asserted-by":"crossref","first-page":"852","DOI":"10.1097\/IAE.0000000000003412","article-title":"Risk of exudative age-related macular degeneration in patients with central serous chorioretinopathy: a nationwide cohort study","volume":"42","author":"Lee","year":"2022","journal-title":"Retina"}],"container-title":["American Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002939423003434?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002939423003434?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T13:54:29Z","timestamp":1757598869000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002939423003434"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1]]},"references-count":34,"alternative-id":["S0002939423003434"],"URL":"https:\/\/doi.org\/10.1016\/j.ajo.2023.08.015","relation":{},"ISSN":["0002-9394"],"issn-type":[{"value":"0002-9394","type":"print"}],"subject":[],"published":{"date-parts":[[2024,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Increased Risk of Optic Neuritis in Patients With Fibromyalgia: Nationwide Population-Based Cohort Study in South Korea","name":"articletitle","label":"Article Title"},{"value":"American Journal of Ophthalmology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajo.2023.08.015","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}