{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,7]],"date-time":"2026-11-07T06:01:09Z","timestamp":1794031269822,"version":"4.8.0"},"reference-count":29,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T00:00:00Z","timestamp":1746057600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T00:00:00Z","timestamp":1746057600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,2,13]],"date-time":"2025-02-13T00:00:00Z","timestamp":1739404800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100005809","name":"Hyderabad Eye Research Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["ajo.com","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["American Journal of Ophthalmology"],"published-print":{"date-parts":[[2025,5]]},"DOI":"10.1016\/j.ajo.2025.02.003","type":"journal-article","created":{"date-parts":[[2025,2,7]],"date-time":"2025-02-07T14:45:52Z","timestamp":1738939552000},"page":"107-118","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"special_numbering":"C","title":["Five- to Twelve-Year Outcomes of Autologous Simple Limbal Epithelial Transplantation: Long-Term Corneal Epithelial Imaging and Phenotypic Analysis"],"prefix":"10.1016","volume":"273","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2455-0536","authenticated-orcid":false,"given":"SWAPNA S","family":"SHANBHAG","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"ANAHITA","family":"KATE","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"SHAYERI","family":"GANGULY","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"SAUMYA","family":"JAKATI","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"RASHMI","family":"DESHMUKH","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5030-5003","authenticated-orcid":false,"given":"SAYAN","family":"BASU","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"Pt 2","key":"10.1016\/j.ajo.2025.02.003_bib0001","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1038\/eye.1989.17","article-title":"The multipotential cells of the limbus","volume":"3","author":"Thoft","year":"1989","journal-title":"Eye (Lond)"},{"issue":"2","key":"10.1016\/j.ajo.2025.02.003_bib0002","first-page":"83","article-title":"Limbal stem cell deficiency: concept, aetiology, clinical presentation, diagnosis and management","volume":"48","author":"Dua","year":"2000","journal-title":"Indian J Ophthalmol"},{"issue":"5","key":"10.1016\/j.ajo.2025.02.003_bib0003","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1016\/S0161-6420(89)32833-8","article-title":"Limbal autograft transplantation for ocular surface disorders","volume":"96","author":"Kenyon","year":"1989","journal-title":"Ophthalmology"},{"issue":"9057","key":"10.1016\/j.ajo.2025.02.003_bib0004","doi-asserted-by":"crossref","first-page":"990","DOI":"10.1016\/S0140-6736(96)11188-0","article-title":"Long-term restoration of damaged corneal surfaces with autologous cultivated corneal epithelium","volume":"349","author":"Pellegrini","year":"1997","journal-title":"Lancet"},{"issue":"7","key":"10.1016\/j.ajo.2025.02.003_bib0005","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1136\/bjophthalmol-2011-301164","article-title":"Simple limbal epithelial transplantation (SLET): a novel surgical technique for the treatment of unilateral limbal stem cell deficiency","volume":"96","author":"Sangwan","year":"2012","journal-title":"Br J Ophthalmol"},{"issue":"5","key":"10.1016\/j.ajo.2025.02.003_bib0006","doi-asserted-by":"crossref","first-page":"1000","DOI":"10.1016\/j.ophtha.2015.12.042","article-title":"Simple limbal epithelial transplantation: long-term clinical outcomes in 125 cases of unilateral chronic ocular surface burns","volume":"123","author":"Basu","year":"2016","journal-title":"Ophthalmology"},{"issue":"8","key":"10.1016\/j.ajo.2025.02.003_bib0007","doi-asserted-by":"crossref","first-page":"1265","DOI":"10.4103\/ijo.IJO_117_19","article-title":"Simple limbal epithelial transplantation (SLET): review of indications, surgical technique, mechanism, outcomes, limitations, and impact","volume":"67","author":"Shanbhag","year":"2019","journal-title":"Indian J Ophthalmol"},{"issue":"2","key":"10.1016\/j.ajo.2025.02.003_bib0008","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1136\/bjophthalmol-2019-314081","article-title":"Autologous limbal stem cell transplantation: a systematic review of clinical outcomes with different surgical techniques","volume":"104","author":"Shanbhag","year":"2020","journal-title":"Br J Ophthalmol"},{"issue":"3","key":"10.1016\/j.ajo.2025.02.003_bib0009","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1080\/02713683.2021.1988985","article-title":"Longitudinal changes in corneal epithelial thickness and reflectivity following simple limbal epithelial transplantation: an optical coherence tomography-based study","volume":"47","author":"Kate","year":"2022","journal-title":"Curr Eye Res"},{"issue":"3","key":"10.1016\/j.ajo.2025.02.003_bib0010","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1097\/ICO.0000000000001820","article-title":"Global consensus on definition, classification, diagnosis, and staging of limbal stem cell deficiency","volume":"38","author":"Deng","year":"2019","journal-title":"Cornea"},{"issue":"12","key":"10.1016\/j.ajo.2025.02.003_bib0011","doi-asserted-by":"crossref","DOI":"10.1136\/bcr-2020-237234","article-title":"Simultaneous surgical management of unilateral limbal stem cell deficiency and symblepharon post chemical burn","volume":"13","author":"Shanbhag","year":"2020","journal-title":"BMJ Case Rep"},{"issue":"1","key":"10.1016\/j.ajo.2025.02.003_bib0012","first-page":"73","article-title":"Limbal epithelium in ocular surface wound healing","volume":"23","author":"Kinoshita","year":"1982","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"3","key":"10.1016\/j.ajo.2025.02.003_bib0013","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1016\/j.ajo.2014.06.002","article-title":"Modified simple limbal epithelial transplantation using cryopreserved amniotic membrane for unilateral limbal stem cell deficiency","volume":"158","author":"Amescua","year":"2014","journal-title":"Am J Ophthalmol"},{"issue":"1","key":"10.1016\/j.ajo.2025.02.003_bib0014","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1097\/ICO.0000000000003279","article-title":"Midterm outcomes of autologous glueless simple limbal epithelial transplantation for unilateral limbal stem cell deficiency","volume":"43","author":"Malyugin","year":"2024","journal-title":"Cornea J"},{"issue":"1","key":"10.1016\/j.ajo.2025.02.003_bib0015","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1097\/ICO.0000000000003526","article-title":"Outcomes of simple limbal epithelial transplantation without amniotic membrane grafting in unilateral limbal stem cell deficiency: a case series of 6 patients","volume":"44","author":"Jain","year":"2025","journal-title":"Cornea"},{"issue":"2","key":"10.1016\/j.ajo.2025.02.003_bib0016","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1097\/ICO.0000000000003688","article-title":"Femtosecond laser-assisted autologous glueless simple limbal epithelial transplantation in unilateral limbal stem cell deficiency: 12-month outcome of the first clinical cases","volume":"44","author":"Malyugin","year":"2025","journal-title":"Cornea"},{"issue":"5","key":"10.1016\/j.ajo.2025.02.003_bib0017","doi-asserted-by":"crossref","first-page":"927","DOI":"10.4103\/ijo.IJO_155_19","article-title":"Reappearance of limbal pigmentation post-simple limbal epithelial transplant","volume":"68","author":"Gupta","year":"2020","journal-title":"Indian J Ophthalmol"},{"issue":"1","key":"10.1016\/j.ajo.2025.02.003_bib0018","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1007\/s10561-018-09746-3","article-title":"Epithelial analysis of simple limbal epithelial transplantation in limbal stem cell deficiency by in vivo confocal microscopy and impression cytology","volume":"20","author":"Prabhasawat","year":"2019","journal-title":"Cell Tissue Bank"},{"key":"10.1016\/j.ajo.2025.02.003_bib0019","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.jtos.2021.06.012","article-title":"Efficacy and outcome of simple limbal epithelial transplantation for limbal stem cell deficiency verified by epithelial phenotypes integrated with clinical evaluation","volume":"22","author":"Prabhasawat","year":"2021","journal-title":"Ocul Surf"},{"issue":"1","key":"10.1016\/j.ajo.2025.02.003_bib0020","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.jtos.2017.11.002","article-title":"The diagnosis of limbal stem cell deficiency","volume":"16","author":"Le","year":"2018","journal-title":"Ocul Surf J"},{"issue":"6","key":"10.1016\/j.ajo.2025.02.003_bib0021","doi-asserted-by":"crossref","first-page":"1130","DOI":"10.3390\/diagnostics11061130","article-title":"High-resolution optical coherence tomography angiography characteristics of limbal stem cell deficiency","volume":"11","author":"Varma","year":"2021","journal-title":"Diagnostics (Basel)"},{"issue":"1","key":"10.1016\/j.ajo.2025.02.003_bib0022","doi-asserted-by":"crossref","first-page":"35","DOI":"10.4103\/0301-4738.202312","article-title":"Preliminary results from the comparison of simple limbal epithelial transplantation with conjunctival limbal autologous transplantation in severe unilateral chronic ocular burns","volume":"65","author":"Arora","year":"2017","journal-title":"Indian J Ophthalmol"},{"issue":"10","key":"10.1016\/j.ajo.2025.02.003_bib0023","doi-asserted-by":"crossref","first-page":"1416","DOI":"10.1136\/bjophthalmol-2015-307348","article-title":"Autologous simple limbal epithelial transplantation for unilateral limbal stem cell deficiency: multicentre results","volume":"100","author":"Vazirani","year":"2016","journal-title":"Br J Ophthalmol"},{"issue":"1","key":"10.1016\/j.ajo.2025.02.003_bib0024","doi-asserted-by":"crossref","first-page":"45","DOI":"10.4103\/ijo.IJO_602_17","article-title":"Results of simple limbal epithelial transplantation in unilateral ocular surface burn","volume":"66","author":"Gupta","year":"2018","journal-title":"Indian J Ophthalmol"},{"issue":"12","key":"10.1016\/j.ajo.2025.02.003_bib0025","doi-asserted-by":"crossref","first-page":"1640","DOI":"10.1136\/bjophthalmol-2017-311506","article-title":"Simple limbal epithelial transplantation (SLET) in failed cultivated limbal epithelial transplantation (CLET) for unilateral chronic ocular burns","volume":"102","author":"Basu","year":"2018","journal-title":"Br J Ophthalmol"},{"key":"10.1016\/j.ajo.2025.02.003_bib0026","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.jtos.2024.01.003","article-title":"Comparative analysis of long-term results of three epithelial cell transplantation procedures for treating limbal stem cell deficiency","volume":"32","author":"Kengpunpanich","year":"2024","journal-title":"Ocul Surf"},{"key":"10.1016\/j.ajo.2025.02.003_bib0027","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1016\/j.jtos.2024.10.007","article-title":"Simple limbal epithelial transplantation versus cultivated limbal epithelial transplantation in ocular burns","volume":"34","author":"Sharma","year":"2024","journal-title":"Ocul Surf"},{"issue":"4","key":"10.1016\/j.ajo.2025.02.003_bib0028","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1016\/j.jtos.2019.09.003","article-title":"Long-term outcomes of conjunctival limbal autograft in patients with unilateral total limbal stem cell deficiency","volume":"17","author":"Eslani","year":"2019","journal-title":"Ocul Surf"},{"issue":"5","key":"10.1016\/j.ajo.2025.02.003_bib0029","doi-asserted-by":"crossref","first-page":"640","DOI":"10.1136\/bjophthalmol-2015-308272","article-title":"Safety outcomes and long-term effectiveness of ex vivo autologous cultured limbal epithelial transplantation for limbal stem cell deficiency","volume":"101","author":"Fasolo","year":"2017","journal-title":"Br J Ophthalmol"}],"container-title":["American Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002939425000558?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002939425000558?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T16:46:13Z","timestamp":1777567573000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002939425000558"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5]]},"references-count":29,"alternative-id":["S0002939425000558"],"URL":"https:\/\/doi.org\/10.1016\/j.ajo.2025.02.003","relation":{},"ISSN":["0002-9394"],"issn-type":[{"value":"0002-9394","type":"print"}],"subject":[],"published":{"date-parts":[[2025,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Five- to Twelve-Year Outcomes of Autologous Simple Limbal Epithelial Transplantation: Long-Term Corneal Epithelial Imaging and Phenotypic Analysis","name":"articletitle","label":"Article Title"},{"value":"American Journal of Ophthalmology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajo.2025.02.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}