{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T08:44:17Z","timestamp":1793263457902,"version":"4.5.0"},"reference-count":46,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["ajo.com","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["American Journal of Ophthalmology"],"published-print":{"date-parts":[[2025,12]]},"DOI":"10.1016\/j.ajo.2025.08.045","type":"journal-article","created":{"date-parts":[[2025,8,22]],"date-time":"2025-08-22T15:50:32Z","timestamp":1755877832000},"page":"414-422","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"special_numbering":"C","title":["Intraocular Pressure and Ocular Perfusion Pressure in Central Serous Chorioretinopathy"],"prefix":"10.1016","volume":"280","author":[{"given":"Felice","family":"Cardillo Piccolino","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4715-8414","authenticated-orcid":false,"given":"Alessandro","family":"Arrigo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1762-3506","authenticated-orcid":false,"given":"Paolo","family":"Forte","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2119-9752","authenticated-orcid":false,"given":"Lorenzo","family":"Mangoni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3750-2886","authenticated-orcid":false,"given":"Jennifer","family":"Cattaneo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniela","family":"Fruttini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3238-9682","authenticated-orcid":false,"given":"Francesco","family":"Bandello","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Massimo","family":"Nicol\u00f2","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3656-1689","authenticated-orcid":false,"given":"Chiara Maria","family":"Eandi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6817-2488","authenticated-orcid":false,"given":"Marco","family":"Lupidi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.ajo.2025.08.045_bib0001","first-page":"1","article-title":"Pathogenesis of disciform detachment of the neuroepithelium","volume":"63","author":"Gass","year":"1967","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.ajo.2025.08.045_bib0002","series-title":"New York Eye Bank for Sight Restoration, Manhattan Eye E. The Macula: a comprehensive text and atlas","author":"Schatz","year":"1979"},{"issue":"3","key":"10.1016\/j.ajo.2025.08.045_bib0003","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1097\/00006982-199414030-00008","article-title":"Central serous chorioretinopathy and indocyanine green angiography","volume":"14","author":"Cardillo Piccolino","year":"1994","journal-title":"Retina"},{"issue":"10","key":"10.1016\/j.ajo.2025.08.045_bib0004","doi-asserted-by":"crossref","first-page":"1469","DOI":"10.1097\/IAE.0b013e3181be0a83","article-title":"Enhanced depth imaging optical coherence tomography of the choroid in central serous chorioretinopathy","volume":"29","author":"Imamura","year":"2009","journal-title":"Retina"},{"issue":"5","key":"10.1016\/j.ajo.2025.08.045_bib0005","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1038\/s41433-024-03253-4","article-title":"Pachychoroid disease: review and update","volume":"9","author":"Cheung","year":"2025","journal-title":"Eye (Lond)"},{"issue":"3","key":"10.1016\/j.ajo.2025.08.045_bib0006","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1016\/j.oret.2023.10.007","article-title":"Choroidal vascular changes on ultrawidefield indocyanine green angiography in Central serous chorioretinopathy: CERTAIN study Report 1","volume":"8","author":"Pauleikhoff","year":"2024","journal-title":"Ophthalmol Retina"},{"key":"10.1016\/j.ajo.2025.08.045_bib0007","doi-asserted-by":"crossref","DOI":"10.1016\/j.preteyeres.2021.100973","article-title":"Venous overload choroidopathy: a hypothetical framework for central serous chorioretinopathy and allied disorders","volume":"86","author":"Spaide","year":"2022","journal-title":"Prog Retin Eye Res"},{"issue":"3","key":"10.1016\/j.ajo.2025.08.045_bib0008","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/j.oret.2020.07.011","article-title":"Scleral thickness in central serous chorioretinopathy","volume":"5","author":"Imanaga","year":"2021","journal-title":"Ophthalmol Retina"},{"issue":"3","key":"10.1016\/j.ajo.2025.08.045_bib0009","doi-asserted-by":"crossref","first-page":"e165","DOI":"10.1111\/aos.16779","article-title":"Influence of scleral thickness on photodynamic therapy outcomes in central serous chorioretinopathy","volume":"103","author":"Forte","year":"2025","journal-title":"Acta Ophthalmol"},{"issue":"1","key":"10.1016\/j.ajo.2025.08.045_bib0010","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/S0002-9394(99)00075-6","article-title":"Systemic findings associated with central serous chorioretinopathy","volume":"128","author":"Tittl","year":"1999","journal-title":"Am J Ophthalmol"},{"issue":"8","key":"10.1016\/j.ajo.2025.08.045_bib0011","doi-asserted-by":"crossref","first-page":"2190","DOI":"10.1038\/s41433-020-01222-1","article-title":"A new potential risk factor for central serous chorioretinopathy: blood pressure variability","volume":"35","author":"Karada\u011f","year":"2021","journal-title":"Eye (Lond)"},{"key":"10.1016\/j.ajo.2025.08.045_bib0012","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.ajo.2022.08.002","article-title":"Vigorous physical activity as a risk factor for central serous chorioretinopathy","volume":"244","author":"Cardillo Piccolino","year":"2022","journal-title":"Am J Ophthalmol"},{"issue":"2","key":"10.1016\/j.ajo.2025.08.045_bib0013","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1097\/00006982-198700720-00009","article-title":"Type-A behavior and central serous chorioretinopathy","volume":"7","author":"Yannuzzi","year":"1987","journal-title":"Retina"},{"issue":"6","key":"10.1016\/j.ajo.2025.08.045_bib0014","doi-asserted-by":"crossref","first-page":"704","DOI":"10.1136\/bjo.87.6.704","article-title":"Psychosomatic aspects in patients with central serous chorioretinopathy","volume":"87","author":"Spahn","year":"2003","journal-title":"Br J Ophthalmol"},{"issue":"1","key":"10.1016\/j.ajo.2025.08.045_bib0015","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.survophthal.2012.05.003","article-title":"24-hour intraocular pressure and ocular perfusion pressure in glaucoma","volume":"58","author":"Quaranta","year":"2013","journal-title":"Surv Ophthalmol"},{"issue":"4","key":"10.1016\/j.ajo.2025.08.045_bib0016","first-page":"204","article-title":"Central serous chorioretinopathy: some considerations on the pathogenesis","volume":"182","author":"Cardillo Piccolino","year":"1981","journal-title":"Ophthalmologica"},{"issue":"10","key":"10.1016\/j.ajo.2025.08.045_bib0017","doi-asserted-by":"crossref","first-page":"3897","DOI":"10.1167\/iovs.18-23995","article-title":"Choroidal vascular reactivity in central serous chorioretinopathy","volume":"59","author":"Cardillo Piccolino","year":"2018","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"12","key":"10.1016\/j.ajo.2025.08.045_bib0018","doi-asserted-by":"crossref","first-page":"4717","DOI":"10.1167\/iovs.05-0268","article-title":"Choroidal hemodynamic changes during isometric exercise in patients with inactive central serous chorioretinopathy","volume":"46","author":"Tittl","year":"2005","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.ajo.2025.08.045_bib0019","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.ajo.2019.10.033","article-title":"Chronic neovascular central serous chorioretinopathy: a stress\/rest optical coherence tomography angiography study","volume":"211","author":"Lupidi","year":"2020","journal-title":"Am J Ophthalmol"},{"issue":"11","key":"10.1016\/j.ajo.2025.08.045_bib0020","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1016\/j.oret.2020.07.026","article-title":"Central serous chorioretinopathy international group. multimodal imaging-based central serous chorioretinopathy classification","volume":"4","author":"Chhablani","year":"2020","journal-title":"Ophthalmol Retina"},{"issue":"3","key":"10.1016\/j.ajo.2025.08.045_bib0021","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1016\/j.ajo.2015.06.016","article-title":"chronic central serous chorioretinopathy imaged by optical coherence tomographic angiography","volume":"160","author":"Quaranta-El Maftouhi","year":"2015","journal-title":"Am J Ophthalmol"},{"issue":"7","key":"10.1016\/j.ajo.2025.08.045_bib0022","doi-asserted-by":"crossref","first-page":"1008","DOI":"10.1097\/IAE.0b013e31816b4b86","article-title":"Posterior cystoid retinal degeneration in central serous chorioretinopathy","volume":"28","author":"Cardillo Piccolino","year":"2008","journal-title":"Retina"},{"issue":"4","key":"10.1016\/j.ajo.2025.08.045_bib0023","doi-asserted-by":"crossref","first-page":"730","DOI":"10.1097\/IAE.0000000000003376","article-title":"Ciliochoroidal effusion in central serous chorioretinopathy","volume":"42","author":"Terao","year":"2022","journal-title":"Retina"},{"issue":"2","key":"10.1016\/j.ajo.2025.08.045_bib0024","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1016\/j.preteyeres.2009.12.002","article-title":"The multifunctional choroid","volume":"29","author":"Nickla","year":"2010","journal-title":"Prog Retin Eye Res"},{"issue":"11","key":"10.1016\/j.ajo.2025.08.045_bib0025","first-page":"2338","article-title":"Choroidal blood flow during isometric exercises","volume":"38","author":"Riva","year":"1997","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.ajo.2025.08.045_bib0026","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1016\/j.ajo.2020.05.040","article-title":"The effect of obstructive sleep apnea on absolute risk of Central serous chorioretinopathy","volume":"218","author":"Pan","year":"2020","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.ajo.2025.08.045_bib0027","unstructured":"Cardillo Piccolino F. ICG choroidal angiography during induced intraocular hypertension. In: Flower A, Slakter JS, Yannuzzi LA, editors. Indocyanine Green Angiography. 1st ed.; 1997. p. 77-8"},{"key":"10.1016\/j.ajo.2025.08.045_bib0028","doi-asserted-by":"crossref","DOI":"10.1007\/s10384-025-01188-1","article-title":"Choroidal circulation time by wide-field indocyanine green angiography in central serous chorioretinopathy","author":"Kawamura","year":"2025","journal-title":"Jpn J Ophthalmol"},{"issue":"3","key":"10.1016\/j.ajo.2025.08.045_bib0029","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1097\/ICB.0000000000001170","article-title":"Central serous chorioretinopathy mimicking idiopathic uveal effusion syndrome","volume":"17","author":"Boulanger","year":"2023","journal-title":"Retin Cases Brief Rep"},{"issue":"4","key":"10.1016\/j.ajo.2025.08.045_bib0030","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1167\/iovs.66.4.75","article-title":"A model of the mechanisms underpinning unconventional aqueous humor outflow","volume":"66","author":"Tweedy","year":"2025","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"4","key":"10.1016\/j.ajo.2025.08.045_bib0031","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/0014-4835(77)90146-4","article-title":"Pressure dependency of transcleral flow","volume":"24","author":"Kleinstein","year":"1977","journal-title":"Exp Eye Res"},{"key":"10.1016\/j.ajo.2025.08.045_bib0032","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1001\/archopht.1965.00970040250024","article-title":"Movement of albumin and dextran through the sclera","volume":"74","author":"Bill","year":"1965","journal-title":"Arch Ophthalmol"},{"key":"10.1016\/j.ajo.2025.08.045_bib0033","series-title":"Proceedings: 24th Australian Fluid Mechanics Conference, Adelaide University","article-title":"Some basic problems of microfluids","author":"Tabeling","year":"2001"},{"issue":"12","key":"10.1016\/j.ajo.2025.08.045_bib0034","first-page":"872","article-title":"Can chronic bulbar hypotony be responsible for uveal effusion? report of two cases","volume":"20","author":"Daniele","year":"1989","journal-title":"Ophthalmic Surg"},{"issue":"1","key":"10.1016\/j.ajo.2025.08.045_bib0035","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1097\/IAE.0b013e318218a95a","article-title":"Transscleral albumin diffusion and suprachoroidal albumin concentration in uveal effusion syndrome","volume":"32","author":"Jackson","year":"2012","journal-title":"Retina"},{"issue":"4","key":"10.1016\/j.ajo.2025.08.045_bib0036","doi-asserted-by":"crossref","first-page":"e252","DOI":"10.1111\/aos.12298","article-title":"Ocular perfusion pressure in glaucoma","volume":"92","author":"Costa","year":"2014","journal-title":"Acta Ophthalmol"},{"issue":"5","key":"10.1016\/j.ajo.2025.08.045_bib0037","doi-asserted-by":"crossref","first-page":"1601","DOI":"10.1007\/s00417-021-05523-3","article-title":"The anterior scleral thickness in eyes with primary open-angle glaucoma","volume":"260","author":"Yan","year":"2022","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"10.1016\/j.ajo.2025.08.045_bib0038","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1097\/IJG.0000000000000166","article-title":"Is there any role for the choroid in glaucoma?","volume":"25","author":"Iman","year":"2016","journal-title":"J Glaucoma"},{"issue":"9","key":"10.1016\/j.ajo.2025.08.045_bib0039","doi-asserted-by":"crossref","first-page":"1260","DOI":"10.1136\/bjophthalmol-2019-315236","article-title":"Short axial length and hyperopic refractive error are risk factors of central serous chorioretinopathy","volume":"104","author":"Terao","year":"2020","journal-title":"Br J Ophthalmol"},{"issue":"10","key":"10.1016\/j.ajo.2025.08.045_bib0040","doi-asserted-by":"crossref","first-page":"1989","DOI":"10.1016\/j.ophtha.2011.03.012","article-title":"Myopia as a risk factor for open-angle glaucoma: a systematic review and meta-analysis","volume":"118","author":"Marcus","year":"2011","journal-title":"Ophthalmology"},{"issue":"2","key":"10.1016\/j.ajo.2025.08.045_bib0041","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1097\/IAE.0b013e3181c2e0f4","article-title":"Frequency of glaucoma in central serous chorioretinopathy: a case-control study","volume":"30","author":"Imamura","year":"2010","journal-title":"Retina"},{"issue":"8","key":"10.1016\/j.ajo.2025.08.045_bib0042","doi-asserted-by":"crossref","first-page":"1371","DOI":"10.1097\/IAE.0000000000004109","article-title":"Prednisolone eye drops as a potential treatment in nonneovascular pachychoroid-related diseases","volume":"44","author":"van den Tillaart","year":"2024","journal-title":"Retina"},{"issue":"13","key":"10.1016\/j.ajo.2025.08.045_bib0043","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1167\/tvst.9.13.6","article-title":"Efficacy of topical carbonic anhydrase inhibitors in reducing duration of chronic Central serous chorioretinopathy","volume":"9","author":"Liew","year":"2020","journal-title":"Transl Vis Sci Technol"},{"key":"10.1016\/j.ajo.2025.08.045_bib0044","doi-asserted-by":"crossref","DOI":"10.1016\/j.preteyeres.2024.101236","article-title":"Central serous chorioretinopathy: an evidence-based treatment guideline","volume":"101","author":"Feenstra","year":"2024","journal-title":"Prog Retin Eye Res"},{"key":"10.1016\/j.ajo.2025.08.045_bib0045","doi-asserted-by":"crossref","DOI":"10.1016\/j.xops.2025.100808","article-title":"Scleral thickness in eyes with pachychoroid pigment epitheliopathy accompanied by keratoconus","author":"Forte","year":"2025","journal-title":"Ophthalmol Science"},{"issue":"7","key":"10.1016\/j.ajo.2025.08.045_bib0046","doi-asserted-by":"crossref","first-page":"1231","DOI":"10.1097\/IAE.0000000000003485","article-title":"Regional scleral thickness as a risk factor for central serous chorioretinopathy","volume":"42","author":"Spaide","year":"2022","journal-title":"Retina"}],"container-title":["American Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002939425004581?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002939425004581?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T04:18:14Z","timestamp":1779855494000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002939425004581"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12]]},"references-count":46,"alternative-id":["S0002939425004581"],"URL":"https:\/\/doi.org\/10.1016\/j.ajo.2025.08.045","relation":{},"ISSN":["0002-9394"],"issn-type":[{"value":"0002-9394","type":"print"}],"subject":[],"published":{"date-parts":[[2025,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Intraocular Pressure and Ocular Perfusion Pressure in Central Serous Chorioretinopathy","name":"articletitle","label":"Article Title"},{"value":"American Journal of Ophthalmology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajo.2025.08.045","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}