{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T11:35:13Z","timestamp":1782819313695,"version":"3.54.5"},"reference-count":33,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,9,1]],"date-time":"2020-09-01T00:00:00Z","timestamp":1598918400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,9,1]],"date-time":"2020-09-01T00:00:00Z","timestamp":1598918400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2020,6,29]],"date-time":"2020-06-29T00:00:00Z","timestamp":1593388800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100010093","name":"King Khaled Eye Specialist Hospital","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100010093","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["American Journal of Ophthalmology Case Reports"],"published-print":{"date-parts":[[2020,9]]},"DOI":"10.1016\/j.ajoc.2020.100806","type":"journal-article","created":{"date-parts":[[2020,7,11]],"date-time":"2020-07-11T21:49:07Z","timestamp":1594504147000},"page":"100806","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":22,"special_numbering":"C","title":["Orbital myeloid sarcoma (chloroma): Report of 2 cases and literature review"],"prefix":"10.1016","volume":"19","author":[{"given":"Mohammad A.","family":"AlSemari","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5543-3773","authenticated-orcid":false,"given":"Marianna","family":"Perrotta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Camilla","family":"Russo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hind M.","family":"Alkatan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Maktabi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Elkhamary","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosa Maria Di","family":"Crescenzo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Massimo","family":"Mascolo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Elefante","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luca","family":"Rombetto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raffaella","family":"Capasso","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diego","family":"Strianese","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"February","key":"10.1016\/j.ajoc.2020.100806_bib1","doi-asserted-by":"crossref","first-page":"319","DOI":"10.2214\/ajr.178.2.1780319","article-title":"Granulocytic sarcoma (chloroma): imaging findings in adults and children","volume":"178","author":"Guermazi","year":"2002","journal-title":"AJR"},{"issue":"October","key":"10.1016\/j.ajoc.2020.100806_bib2","first-page":"1497","article-title":"Granulocytic sarcoma of the temporal bone","volume":"23","author":"Lee","year":"2002","journal-title":"AJNR"},{"key":"10.1016\/j.ajoc.2020.100806_bib3","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1007\/s12253-008-9028-x","article-title":"Orbital tumour as initial manifestation of acute myeloid Leukemia\u00a0: granulocytic sarcoma: case report","volume":"14","author":"Maka","year":"2008","journal-title":"Pathol Oncol Res"},{"issue":"8","key":"10.1016\/j.ajoc.2020.100806_bib4","first-page":"1704","article-title":"Granulocytic sarcoma presenting as an orbital mass: report of two cases","volume":"7","author":"Thakur","year":"2013","journal-title":"J Clin Diagn Res"},{"issue":"3","key":"10.1016\/j.ajoc.2020.100806_bib27","doi-asserted-by":"crossref","first-page":"184","DOI":"10.5045\/br.2017.52.3.184","article-title":"Clinical characteristics and treatment outcomes of isolated myeloid sarcoma without bone marrow involvement: a single-institution experience","volume":"52","author":"Lee","year":"2017","journal-title":"Blood Res"},{"issue":"10","key":"10.1016\/j.ajoc.2020.100806_bib5","doi-asserted-by":"crossref","first-page":"1615","DOI":"10.1182\/blood-2013-10-535716","article-title":"Transplantation for children with acute myeloid leukemia: a comparison of outcomes with reduced intensity and myeloablative regimens","volume":"123","author":"Bitan","year":"2014","journal-title":"Blood"},{"key":"10.1016\/j.ajoc.2020.100806_bib6","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1038\/sj.leu.2404491","article-title":"Myeloid sarcoma: clinico-pathologic, phenotypic and cytogenetic analysis of 92 adult patients","volume":"21","author":"Pileri","year":"2007","journal-title":"Leukemia"},{"issue":"6","key":"10.1016\/j.ajoc.2020.100806_bib7","first-page":"444","article-title":"Myeloid sarcoma in children \u2013 diagnostic and therapeutic difficulties","volume":"20","author":"Samborska","year":"2016","journal-title":"Contemp Oncol"},{"key":"10.1016\/j.ajoc.2020.100806_bib8","first-page":"208","article-title":"Two anomalous localizations of mucocele: clinical presentation and retrospective review","volume":"27","author":"Cavazza","year":"2007","journal-title":"Acta Otorhinolaryngol Ital"},{"key":"10.1016\/j.ajoc.2020.100806_bib9","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1080\/01676830701523889","article-title":"Orbital heterotopic glial tissue presenting as exotropia","volume":"27","author":"Kiratli","year":"2008","journal-title":"Orbit"},{"key":"10.1016\/j.ajoc.2020.100806_bib10","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1159\/000354963","article-title":"Orbital lymphoma mimicking lacrimal gland pleomorphic adenoma","volume":"4","author":"Strianese","year":"2013","journal-title":"Case Rep Ophtalmol"},{"issue":"4","key":"10.1016\/j.ajoc.2020.100806_bib11","first-page":"215","article-title":"Orbital pseudotumor: clinical features and outcomes","volume":"25","author":"Chirapapaisan","year":"2007","journal-title":"Asian Pac J Allergy Immunol"},{"issue":"21","key":"10.1016\/j.ajoc.2020.100806_bib12","article-title":"Unilateral proptosis in thyroid eye disease with subsequent contralateral involvement: retrospective follow-up study","volume":"13","author":"Strianese","year":"2013","journal-title":"BMC Ophthalmol"},{"issue":"3","key":"10.1016\/j.ajoc.2020.100806_bib13","doi-asserted-by":"crossref","first-page":"373","DOI":"10.21037\/qims.2017.04.04","article-title":"Orbitofrontal cholesterol granuloma: case report and review of the literature","volume":"7","author":"Ugga","year":"2017","journal-title":"Quant Imaging Med Surg"},{"issue":"4","key":"10.1016\/j.ajoc.2020.100806_bib14","first-page":"265","article-title":"Granulocytic sarcoma: a systematic review","volume":"3","author":"Yilmaz","year":"2013","journal-title":"Am J Blood Res"},{"key":"10.1016\/j.ajoc.2020.100806_bib16","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1038\/sj.eye.6701912","article-title":"Neuroblastoma with orbital metastasis: ophthalmic presentation and role of ophthalmologists","volume":"20","author":"Ahmed","year":"2006","journal-title":"Eye"},{"issue":"March\/April","key":"10.1016\/j.ajoc.2020.100806_bib17","first-page":"263","article-title":"Granulocytic sarcoma","volume":"12","author":"Jakobiec","year":"1991","journal-title":"AJNR"},{"issue":"2","key":"10.1016\/j.ajoc.2020.100806_bib18","doi-asserted-by":"crossref","first-page":"66","DOI":"10.3342\/ceo.2009.2.2.66","article-title":"Granulocytic sarcoma in the head and neck: CT and MR imaging findings","volume":"2","author":"Noh","year":"2009","journal-title":"Clin Exp Otorhinolaryngol"},{"issue":"5","key":"10.1016\/j.ajoc.2020.100806_bib19","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1007\/s00234-014-1332-4","article-title":"Diagnostic accuracy of short-time inversion recovery sequence in Graves' ophthalmopathy before and after prednisone treatment","volume":"56","author":"Tortora","year":"2014","journal-title":"Neuroradiology"},{"key":"10.1016\/j.ajoc.2020.100806_bib20","article-title":"Orbital tumours and tumour-like lesions: exploring the armamentarium of multiparametric imaging","author":"Purohit","year":"2015","journal-title":"Insights Imaging"},{"issue":"6","key":"10.1016\/j.ajoc.2020.100806_bib15","doi-asserted-by":"crossref","first-page":"1777","DOI":"10.1148\/rg.276075138","article-title":"From the archives of the AFIP pediatric orbit tumors and tumorlike lesions: nonosseous lesions of the extraocular orbit","volume":"27","author":"Chung","year":"2007","journal-title":"Radiographics"},{"issue":"2","key":"10.1016\/j.ajoc.2020.100806_bib24","first-page":"1","article-title":"Myeloid sarcomas: a histologic, immunohistochemical, and cytogenetic study","volume":"42","author":"Alexiev","year":"2007","journal-title":"Diagn Pathol"},{"issue":"6","key":"10.1016\/j.ajoc.2020.100806_bib25","doi-asserted-by":"crossref","first-page":"1739","DOI":"10.1002\/cncr.10399","article-title":"Comparison in treatments of nonleukemic granulocytic sarcoma. Report of two cases and a review of 72 cases in the literature","volume":"94","author":"Yamauchi","year":"2002","journal-title":"Cancer"},{"issue":"June","key":"10.1016\/j.ajoc.2020.100806_bib22","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1259\/bjr\/16630393","article-title":"Intracranial myeloid sarcoma: conventional and advanced MRI findings","volume":"80","author":"Hakyemez","year":"2007","journal-title":"Br J Radiol"},{"issue":"4","key":"10.1016\/j.ajoc.2020.100806_bib21","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1177\/197140091302600402","article-title":"Semiautomatic regional segmentation to measure orbital fat volumes in thyroid-associated ophthalmopathy. A validation study","volume":"26","author":"Comerci","year":"2013","journal-title":"Neuroradiol J"},{"key":"10.1016\/j.ajoc.2020.100806_bib32","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1007\/s00234-011-0838-2","article-title":"Differentiation between benign and malignant orbital tumors at 3-T diffusion MR-imaging","volume":"53","author":"Razek","year":"2011","journal-title":"Neuroradiology"},{"key":"10.1016\/j.ajoc.2020.100806_bib23","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1309\/AJCP1ZA7HYZKAZHS","article-title":"Myeloid sarcoma. Extramedullary manifestation of myeloid disorders","volume":"132","author":"Campidelli","year":"2009","journal-title":"Am J Clin Pathol"},{"issue":"6","key":"10.1016\/j.ajoc.2020.100806_bib33","doi-asserted-by":"crossref","first-page":"411","DOI":"10.14735\/amko2016411","article-title":"Molecular genetic testing for acute myeloid leukemia","volume":"29","author":"Jane\u010dkov\u00e1","year":"2016","journal-title":"Klin Onkol"},{"issue":"6","key":"10.1016\/j.ajoc.2020.100806_bib31","doi-asserted-by":"crossref","first-page":"461","DOI":"10.4103\/0256-4947.51679","article-title":"Myeloid sarcoma of the orbit","volume":"28","author":"Alkatan","year":"2008","journal-title":"Ann S Med"},{"issue":"2","key":"10.1016\/j.ajoc.2020.100806_bib26","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1016\/j.survophthal.2013.06.004","article-title":"Orbital extra-medullary granulocytic sarcoma: clinicopathologic correlation with immunohistochemical features","volume":"59","author":"Aggarwal","year":"2014","journal-title":"Surv Ophthalmol"},{"key":"10.1016\/j.ajoc.2020.100806_bib28","doi-asserted-by":"crossref","first-page":"1100","DOI":"10.1038\/sj.leu.2402958","article-title":"Outcome in patients with nonleukemic granulocytic sarcoma treated with chemotherapy with or without radiotherapy","volume":"17","author":"Tsimberidou","year":"2003","journal-title":"Leukemia"},{"issue":"1","key":"10.1016\/j.ajoc.2020.100806_bib29","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/j.biopha.2012.10.014","article-title":"Is there a \u201c\u2018gold\u2019\u201d standard treatment for patients with isolated myeloid sarcoma?","volume":"67","author":"Antic","year":"2013","journal-title":"Biomed Pharmacother"},{"issue":"5","key":"10.1016\/j.ajoc.2020.100806_bib30","doi-asserted-by":"crossref","first-page":"1816","DOI":"10.1016\/j.ijrobp.2011.02.057","article-title":"Radiation therapy for chloroma (granulocytic sarcoma)","volume":"82","author":"Bakst","year":"2012","journal-title":"Int J Radiat Oncol Biol Phys"}],"container-title":["American Journal of Ophthalmology Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2451993620301390?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2451993620301390?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T15:00:23Z","timestamp":1762527623000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2451993620301390"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,9]]},"references-count":33,"alternative-id":["S2451993620301390"],"URL":"https:\/\/doi.org\/10.1016\/j.ajoc.2020.100806","relation":{},"ISSN":["2451-9936"],"issn-type":[{"value":"2451-9936","type":"print"}],"subject":[],"published":{"date-parts":[[2020,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Orbital myeloid sarcoma (chloroma): Report of 2 cases and literature review","name":"articletitle","label":"Article Title"},{"value":"American Journal of Ophthalmology Case Reports","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajoc.2020.100806","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"100806"}}