{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,25]],"date-time":"2026-02-25T21:21:19Z","timestamp":1772054479093,"version":"3.50.1"},"reference-count":26,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,12,1]],"date-time":"2020-12-01T00:00:00Z","timestamp":1606780800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,12,1]],"date-time":"2020-12-01T00:00:00Z","timestamp":1606780800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2020,9,16]],"date-time":"2020-09-16T00:00:00Z","timestamp":1600214400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"name":"San Francisco Retina Foundation"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["American Journal of Ophthalmology Case Reports"],"published-print":{"date-parts":[[2020,12]]},"DOI":"10.1016\/j.ajoc.2020.100927","type":"journal-article","created":{"date-parts":[[2020,9,19]],"date-time":"2020-09-19T20:45:35Z","timestamp":1600548335000},"page":"100927","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"special_numbering":"C","title":["Clinical course of von Szily reaction: Case report and comprehensive review of the literature"],"prefix":"10.1016","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2462-0485","authenticated-orcid":false,"given":"Caleb C.","family":"Ng","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Judy J.","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anita","family":"Agarwal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"Jr.","given":"Emmett T.","family":"Cunningham","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ajoc.2020.100927_bib1","first-page":"593","article-title":"Experimental endogenous transmission of infection from bulbus to bulbus","volume":"72","author":"Von Szily","year":"1924","journal-title":"Klin Monatsbl Augenheilkd"},{"issue":"9","key":"10.1016\/j.ajoc.2020.100927_bib2","first-page":"2462","article-title":"Neural spread of herpes simplex virus after anterior chamber inoculation","volume":"32","author":"Vann","year":"1991","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"8","key":"10.1016\/j.ajoc.2020.100927_bib3","first-page":"3251","article-title":"Sparing of the ipsilateral retina after anterior chamber inoculation of HSV-1: requirement for either CD4+ or CD8+ T cells","volume":"35","author":"Azumi","year":"1994","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"1-2","key":"10.1016\/j.ajoc.2020.100927_bib4","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/S0165-5728(97)00152-5","article-title":"Spread of HSV-1 to the suprachiasmatic nuclei and retina in T cell depleted BALB\/c mice","volume":"80","author":"Matsubara","year":"1997","journal-title":"J Neuroimmunol"},{"key":"10.1016\/j.ajoc.2020.100927_bib5","first-page":"1065","article-title":"Ocular disease induced in mice by anterior chamber inoculation of herpes simplex virus","volume":"25","author":"Whittum","year":"1984","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"1","key":"10.1016\/j.ajoc.2020.100927_bib6","first-page":"68","article-title":"Immunohistopathologic findings in herpes simplex virus chorioretinitis in the von Szily model","volume":"33","author":"Zaltas","year":"1992","journal-title":"Investig Ophthalmol Vis Sci"},{"issue":"3","key":"10.1016\/j.ajoc.2020.100927_bib7","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1016\/j.ajo.2006.10.040","article-title":"Two patients with the von Szily reaction: herpetic keratitis and contralateral retinal necrosis","volume":"143","author":"Smith","year":"2007","journal-title":"Am J Ophthalmol"},{"issue":"12","key":"10.1016\/j.ajoc.2020.100927_bib8","doi-asserted-by":"crossref","first-page":"1309","DOI":"10.1016\/S0161-6420(82)34628-X","article-title":"The acute retinal necrosis syndrome: Part 1: clinical manifestations","volume":"89","author":"Fisher","year":"1982","journal-title":"Ophthalmology"},{"issue":"11","key":"10.1016\/j.ajoc.2020.100927_bib9","doi-asserted-by":"crossref","first-page":"1418","DOI":"10.1016\/S0161-6420(86)33551-6","article-title":"Acute retinal necrosis syndrome following herpes zoster dermatitis","volume":"93","author":"Yeo","year":"1986","journal-title":"Ophthalmology"},{"issue":"6","key":"10.1016\/j.ajoc.2020.100927_bib10","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1016\/S0161-6420(87)33405-0","article-title":"Association of varicella zoster dermatitis with acute retinal necrosis syndrome","volume":"94","author":"Browning","year":"1987","journal-title":"Ophthalmology"},{"issue":"6","key":"10.1016\/j.ajoc.2020.100927_bib11","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1016\/S0161-6420(89)32823-5","article-title":"Herpes simplex virus type 1: a cause of the acute retinal necrosis syndrome","volume":"96","author":"Lewis","year":"1989","journal-title":"Ophthalmology"},{"issue":"6","key":"10.1016\/j.ajoc.2020.100927_bib12","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1016\/S0002-9394(14)77289-7","article-title":"Magnetic resonance imaging in a patient with herpes zoster keratouveitis and contralateral acute retinal necrosis","volume":"112","author":"Farrell","year":"1991","journal-title":"Am J Ophthalmol"},{"issue":"5","key":"10.1016\/j.ajoc.2020.100927_bib13","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1016\/S0021-5155(00)00207-0","article-title":"Acute retinal necrosis following contralateral herpes zoster ophthalmicus","volume":"44","author":"Nakanishi","year":"2000","journal-title":"Jpn J Ophthalmol"},{"issue":"6","key":"10.1016\/j.ajoc.2020.100927_bib14","doi-asserted-by":"crossref","first-page":"778","DOI":"10.1038\/sj.eye.6700204","article-title":"Unilateral varicella zoster virus ophthalmicus and contralateral acute retinal necrosis","volume":"16","author":"Matthews","year":"2002","journal-title":"Eye"},{"issue":"1","key":"10.1016\/j.ajoc.2020.100927_bib15","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1186\/1471-2334-13-170","article-title":"Similar herpes zoster incidence across Europe: results from a systematic literature review","volume":"13","author":"Pinchinat","year":"2013","journal-title":"BMC Infect Dis"},{"issue":"No. 11","key":"10.1016\/j.ajoc.2020.100927_bib16","doi-asserted-by":"crossref","first-page":"1341","DOI":"10.4065\/82.11.1341","article-title":"A population-based study of the incidence and complication rates of herpes zoster before zoster vaccine introduction","volume":"82","author":"Yawn","year":"2007","journal-title":"Mayo Clin Proc"},{"issue":"May","key":"10.1016\/j.ajoc.2020.100927_bib17","doi-asserted-by":"crossref","first-page":"d1056","DOI":"10.2741\/A831","article-title":"T cells and aging, January 2002 update","volume":"7","author":"Pawelec","year":"2002","journal-title":"Front Biosci"},{"issue":"6","key":"10.1016\/j.ajoc.2020.100927_bib18","doi-asserted-by":"crossref","first-page":"e218","DOI":"10.1016\/S1470-2045(12)70582-X","article-title":"Cytokine patterns in patients with cancer: a systematic review","volume":"14","author":"Lippitz","year":"2013","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.ajoc.2020.100927_bib19","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1016\/S0002-9394(03)00095-3","article-title":"Acute retinal necrosis following epidural steroid injections","volume":"136","author":"Browning","year":"2003","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.ajoc.2020.100927_bib20","doi-asserted-by":"crossref","first-page":"72","DOI":"10.3109\/09273948.2010.520404","article-title":"Herpetic necrotizing retinitis following flucinolone acetonide intravitreal implant","volume":"19","author":"Ramaiya","year":"2011","journal-title":"Ocul Immunol Inflamm"},{"key":"10.1016\/j.ajoc.2020.100927_bib21","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1007\/s10792-010-9380-1","article-title":"Unilateral acute retinal necrosis in a multiple sclerosis patient treated with high-dose systemic steroids","volume":"30","author":"Saatci","year":"2010","journal-title":"Int Ophthalmol"},{"issue":"5","key":"10.1016\/j.ajoc.2020.100927_bib22","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1097\/IAE.0b013e3181c7013c","article-title":"Long-term follow-up of acute retinal necrosis","volume":"30","author":"Meghpara","year":"2010","journal-title":"Retina"},{"issue":"3","key":"10.1016\/j.ajoc.2020.100927_bib23","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1016\/S0002-9394(14)76725-X","article-title":"Decrease in the risk of bilateral acute retinal necrosis by acyclovir therapy","volume":"112","author":"Palay","year":"1991","journal-title":"Am J Ophthalmol"},{"issue":"5","key":"10.1016\/j.ajoc.2020.100927_bib24","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1136\/bjophthalmol-2012-301983","article-title":"Emerging concepts in the management of acute retinal necrosis","volume":"97","author":"Wong","year":"2013","journal-title":"Br J Ophthalmol"},{"issue":"2","key":"10.1016\/j.ajoc.2020.100927_bib25","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/0002-9394(74)90086-5","article-title":"Iritis and iris atrophy in herpes zoster ophthalmicus","volume":"78","author":"Marsh","year":"1974","journal-title":"Am J Ophthalmol"},{"issue":"7","key":"10.1016\/j.ajoc.2020.100927_bib26","doi-asserted-by":"crossref","first-page":"1460","DOI":"10.1016\/j.ophtha.2012.01.033","article-title":"Clinical features and presentation of infectious scleritis from herpes viruses: a report of 35 cases","volume":"119","author":"Gonzalez-Gonzalez","year":"2012","journal-title":"Ophthalmology"}],"container-title":["American Journal of Ophthalmology Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2451993620302425?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2451993620302425?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T15:00:13Z","timestamp":1762527613000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2451993620302425"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,12]]},"references-count":26,"alternative-id":["S2451993620302425"],"URL":"https:\/\/doi.org\/10.1016\/j.ajoc.2020.100927","relation":{},"ISSN":["2451-9936"],"issn-type":[{"value":"2451-9936","type":"print"}],"subject":[],"published":{"date-parts":[[2020,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Clinical course of von Szily reaction: Case report and comprehensive review of the literature","name":"articletitle","label":"Article Title"},{"value":"American Journal of Ophthalmology Case Reports","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajoc.2020.100927","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"100927"}}