{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,20]],"date-time":"2026-03-20T23:40:10Z","timestamp":1774050010627,"version":"3.50.1"},"reference-count":16,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,11,3]],"date-time":"2022-11-03T00:00:00Z","timestamp":1667433600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["American Journal of Ophthalmology Case Reports"],"published-print":{"date-parts":[[2022,12]]},"DOI":"10.1016\/j.ajoc.2022.101748","type":"journal-article","created":{"date-parts":[[2022,11,7]],"date-time":"2022-11-07T21:23:36Z","timestamp":1667856216000},"page":"101748","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["Visual loss as the initial manifestation of an ignored disseminated prostate cancer: A case report"],"prefix":"10.1016","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7298-6858","authenticated-orcid":false,"given":"Alejandra B.","family":"Miranda","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7749-2547","authenticated-orcid":false,"given":"Carla D.","family":"Guantay","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Evangelina","family":"Esp\u00f3sito","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julio A.","family":"Urrets-Zaval\u00eda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"7","key":"10.1016\/j.ajoc.2022.101748_bib1","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1055\/s-0031-1273474","article-title":"Intraokulare Manifestationen bei systemischen Tumorerkrankungen [Intraocular manifestations of systemic neoplasms]","volume":"228","author":"Bechrakis","year":"2011","journal-title":"Klin Monbl Augenheilkd"},{"issue":"1","key":"10.1016\/j.ajoc.2022.101748_bib2","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1186\/s12886-018-0948-2","article-title":"Cancer-associated retinopathy preceding the diagnosis of cancer","volume":"18","author":"Hoogewoud","year":"2018","journal-title":"BMC Ophthalmol"},{"key":"10.1016\/j.ajoc.2022.101748_bib3","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/B978-0-12-811161-1.00006-2","article-title":"Brain metastasis: clinical manifestations, symptom management, and palliative care","volume":"149","author":"Noh","year":"2018","journal-title":"Handb Clin Neurol"},{"key":"10.1016\/j.ajoc.2022.101748_bib4","doi-asserted-by":"crossref","DOI":"10.1155\/2013\/892523","article-title":"Optic neuritis as isolated manifestation of leptomeningeal carcinomatosis: a case report and systematic review of ocular manifestations of neoplastic meningitis","volume":"2013","author":"Lanfranconi","year":"2013","journal-title":"Neurol Res Int"},{"issue":"1","key":"10.1016\/j.ajoc.2022.101748_bib5","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1007\/s12032-012-0429-z","article-title":"Leptomeningeal metastases from genitourinary cancer: the university of Texas MD anderson cancer center experience","volume":"30","author":"Yust-Katz","year":"2013","journal-title":"Med Oncol"},{"issue":"5","key":"10.1016\/j.ajoc.2022.101748_bib6","doi-asserted-by":"crossref","DOI":"10.3834\/uij.1944-5784.2010.10.11","article-title":"Prostate cancer presenting with neurologic deficits and visual symptoms: uncommon presentation of a common malignancy","volume":"3","author":"Bhargava","year":"2010","journal-title":"UroToday Int J"},{"issue":"6","key":"10.1016\/j.ajoc.2022.101748_bib7","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1001\/archopht.1972.01000020644006","article-title":"Prostatic carcinoma metastatic to optic nerve and choroid. Association with changes resembling papilledema","volume":"87","author":"Zappia","year":"1972","journal-title":"Arch Ophthalmol"},{"issue":"9","key":"10.1016\/j.ajoc.2022.101748_bib8","doi-asserted-by":"crossref","first-page":"1116","DOI":"10.1038\/sj.eye.6702155","article-title":"Decreased vision as the initial presenting symptom of disseminated prostatic disease","volume":"20","author":"Connell","year":"2006","journal-title":"Eye"},{"issue":"9","key":"10.1016\/j.ajoc.2022.101748_bib9","first-page":"1834","article-title":"Neurologic complications of prostate cancer","volume":"65","author":"Benjamin","year":"2002","journal-title":"Am Fam Physician"},{"issue":"2","key":"10.1016\/j.ajoc.2022.101748_bib10","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1001\/archopht.118.2.217","article-title":"Metastatic neoplasms in the optic disc: the 1999 Bjerrum lecture: Part 2","volume":"118","author":"Shields","year":"2000","journal-title":"Arch Ophthalmol"},{"issue":"1","key":"10.1016\/j.ajoc.2022.101748_bib11","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1159\/000510808","article-title":"Leptomeningeal carcinomatosis with delayed ocular manifestations","volume":"14","author":"Czyz","year":"2021","journal-title":"Case Rep Oncol"},{"issue":"3","key":"10.1016\/j.ajoc.2022.101748_bib12","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1007\/s11060-021-03924-2","article-title":"Leptomeningeal metastases: the future is now","volume":"156","author":"Lukas","year":"2022","journal-title":"J Neuro Oncol"},{"issue":"9","key":"10.1016\/j.ajoc.2022.101748_bib13","doi-asserted-by":"crossref","first-page":"810","DOI":"10.1007\/s004150050459","article-title":"The diagnostic accuracy of magnetic resonance imaging and cerebrospinal fluid cytology in leptomeningeal metastasis","volume":"246","author":"Straathof","year":"1999","journal-title":"J Neurol"},{"issue":"4","key":"10.1016\/j.ajoc.2022.101748_bib14","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1002\/1097-0142(19820215)49:4<759::AID-CNCR2820490427>3.0.CO;2-7","article-title":"Diagnosis and treatment of leptomeningeal metastases from solid tumors: experience with 90 patients","volume":"49","author":"Wasserstrom","year":"1982","journal-title":"Cancer"},{"issue":"19","key":"10.1016\/j.ajoc.2022.101748_bib15","doi-asserted-by":"crossref","first-page":"3281","DOI":"10.1200\/JCO.2008.16.4533","article-title":"Diagnosing leptomeningeal carcinomatosis with negative CSF cytology in advanced prostate cancer","volume":"26","author":"Bernstein","year":"2008","journal-title":"J Clin Oncol"},{"issue":"1","key":"10.1016\/j.ajoc.2022.101748_bib16","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1007\/s10585-009-9298-z","article-title":"Leptomeningeal metastases from prostate cancer: an emerging clinical conundrum","volume":"27","author":"Orphanos","year":"2010","journal-title":"Clin Exp Metastasis"}],"container-title":["American Journal of Ophthalmology Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2451993622004947?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2451993622004947?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T15:02:46Z","timestamp":1762527766000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2451993622004947"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12]]},"references-count":16,"alternative-id":["S2451993622004947"],"URL":"https:\/\/doi.org\/10.1016\/j.ajoc.2022.101748","relation":{},"ISSN":["2451-9936"],"issn-type":[{"value":"2451-9936","type":"print"}],"subject":[],"published":{"date-parts":[[2022,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Visual loss as the initial manifestation of an ignored disseminated prostate cancer: A case report","name":"articletitle","label":"Article Title"},{"value":"American Journal of Ophthalmology Case Reports","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajoc.2022.101748","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"101748"}}