{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T19:22:17Z","timestamp":1791400937791,"version":"4.3.3"},"reference-count":18,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2010,2,1]],"date-time":"2010-02-01T00:00:00Z","timestamp":1264982400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2010,2,1]],"date-time":"2010-02-01T00:00:00Z","timestamp":1264982400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["ajodo.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["American Journal of Orthodontics and Dentofacial Orthopedics"],"published-print":{"date-parts":[[2010,2]]},"DOI":"10.1016\/j.ajodo.2009.10.019","type":"journal-article","created":{"date-parts":[[2010,2,9]],"date-time":"2010-02-09T10:13:28Z","timestamp":1265710408000},"page":"160.e1-160.e7","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":62,"title":["Primary failure of eruption and PTH1R: The importance of a genetic diagnosis for orthodontic treatment planning"],"prefix":"10.1016","volume":"137","author":[{"given":"Sylvia A.","family":"Frazier-Bowers","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Darrin","family":"Simmons","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. Timothy","family":"Wright","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William R.","family":"Proffit","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James L.","family":"Ackerman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ajodo.2009.10.019_bib1","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/0002-9416(81)90217-7","article-title":"Primary failure of eruption: a possible cause of posterior open bite","volume":"80","author":"Proffit","year":"1981","journal-title":"Am J Orthod"},{"key":"10.1016\/j.ajodo.2009.10.019_bib2","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1111\/j.1399-0004.1978.tb01186.x","article-title":"Familial reinclusion of permanent molars","volume":"13","author":"Bosker","year":"1978","journal-title":"Clin Genet"},{"key":"10.1016\/j.ajodo.2009.10.019_bib3","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1179\/bjo.17.2.109","article-title":"Familial primary failure of eruption of permanent teeth","volume":"17","author":"Brady","year":"1990","journal-title":"Br J Orthod"},{"key":"10.1016\/j.ajodo.2009.10.019_bib4","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1179\/bjo.18.3.233","article-title":"Familial posterior open bite: a primary failure of eruption","volume":"18","author":"Ireland","year":"1991","journal-title":"Br J Orthod"},{"key":"10.1016\/j.ajodo.2009.10.019_bib5","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/0300-5712(92)90045-E","article-title":"Secondary retention of permanent molars: a report of five families","volume":"20","author":"Raghoebar","year":"1992","journal-title":"J Dent"},{"key":"10.1016\/j.ajodo.2009.10.019_bib6","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1046\/j.1365-263x.2000.00186.x","article-title":"Primary failure of eruption in the permanent dentition of siblings","volume":"10","author":"DiBiase","year":"2000","journal-title":"Int J Paediatr Dent"},{"key":"10.1016\/j.ajodo.2009.10.019_bib7","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1016\/j.ajodo.2006.09.038","article-title":"Primary failure of eruption: further characterization of a rare eruption disorder","volume":"131","author":"Frazier-Bowers","year":"2007","journal-title":"Am J Orthod Dentofacial Orthop"},{"key":"10.1016\/j.ajodo.2009.10.019_bib8","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1111\/j.1601-6343.2009.01440.x","article-title":"Genetic analysis of familial non-syndromic primary failure of eruption","volume":"12","author":"Frazier-Bowers","year":"2009","journal-title":"Orthod Craniofac Res"},{"key":"10.1016\/j.ajodo.2009.10.019_bib9","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1016\/j.ajhg.2008.11.006","article-title":"PTHR1 loss-of-function mutations in familial, nonsyndromic primary failure of tooth eruption","volume":"83","author":"Decker","year":"2008","journal-title":"Am J Hum Genet"},{"key":"10.1016\/j.ajodo.2009.10.019_bib10","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1172\/JCI2918","article-title":"Absence of functional receptors for parathyroid hormone and parathyroid hormone-related peptide in Blomstrand chondrodysplasia","volume":"102","author":"Jobert","year":"1998","journal-title":"J Clin Invest"},{"key":"10.1016\/j.ajodo.2009.10.019_bib11","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1093\/hmg\/ddi001","article-title":"Recessive mutations in PTHR1 cause contrasting skeletal dysplasias in Eiken and Blomstrand syndromes","volume":"14","author":"Duchatelet","year":"2005","journal-title":"Hum Mol Genet"},{"key":"10.1016\/j.ajodo.2009.10.019_bib12","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1007\/BF00572767","article-title":"A new familial skeletal dysplasia with severely retarded ossification and abnormal modeling of bones especially of the epiphyses, the hands, and feet","volume":"141","author":"Eiken","year":"1984","journal-title":"Eur J Pediatr"},{"key":"10.1016\/j.ajodo.2009.10.019_bib13","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1038\/ng844","article-title":"A mutant PTH\/PTHrP type I receptor in enchondromatosis","volume":"30","author":"Hopyan","year":"2002","journal-title":"Nat Genet"},{"key":"10.1016\/j.ajodo.2009.10.019_bib14","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1016\/S0022-2836(05)80360-2","article-title":"Basic local alignment search tool","volume":"215","author":"Altschul","year":"1990","journal-title":"J Mol Biol"},{"key":"10.1016\/j.ajodo.2009.10.019_bib15","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1007\/BF02388725","article-title":"A case of lethal congenital dwarfism with accelerated skeletal maturation","volume":"15","author":"Blomstrand","year":"1985","journal-title":"Pediatr Radiol"},{"key":"10.1016\/j.ajodo.2009.10.019_bib16","first-page":"1","article-title":"The lethal osteochondrodysplasias","volume":"19","author":"Spranger","year":"1990","journal-title":"Adv Hum Genet"},{"key":"10.1016\/j.ajodo.2009.10.019_bib17","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1136\/jmg.30.2.155","article-title":"A lethal skeletal dysplasia with generalised sclerosis and advanced skeletal maturation: Blomstrand chondrodysplasia?","volume":"30","author":"Young","year":"1993","journal-title":"J Med Genet"},{"key":"10.1016\/j.ajodo.2009.10.019_bib18","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1177\/154405910808700509","article-title":"Mechanisms of tooth eruption and orthodontic tooth movement","volume":"87","author":"Wise","year":"2008","journal-title":"J Dent Res"}],"container-title":["American Journal of Orthodontics and Dentofacial Orthopedics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0889540609011573?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0889540609011573?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T08:48:27Z","timestamp":1760172507000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0889540609011573"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,2]]},"references-count":18,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2010,2]]}},"alternative-id":["S0889540609011573"],"URL":"https:\/\/doi.org\/10.1016\/j.ajodo.2009.10.019","relation":{},"ISSN":["0889-5406"],"issn-type":[{"value":"0889-5406","type":"print"}],"subject":[],"published":{"date-parts":[[2010,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Primary failure of eruption and PTH1R: The importance of a genetic diagnosis for orthodontic treatment planning","name":"articletitle","label":"Article Title"},{"value":"American Journal of Orthodontics and Dentofacial Orthopedics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajodo.2009.10.019","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"https:\/\/doi.org\/10.1016\/j.ajodo.2009.10.021","name":"associatedlink","label":"CrossRef DOI link to the associated document"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2010 American Association of Orthodontists. Published by Mosby, Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}