{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T10:25:06Z","timestamp":1780482306300,"version":"3.54.1"},"reference-count":22,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2011,12,1]],"date-time":"2011-12-01T00:00:00Z","timestamp":1322697600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2011,12,1]],"date-time":"2011-12-01T00:00:00Z","timestamp":1322697600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["ajodo.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["American Journal of Orthodontics and Dentofacial Orthopedics"],"published-print":{"date-parts":[[2011,12]]},"DOI":"10.1016\/j.ajodo.2011.06.026","type":"journal-article","created":{"date-parts":[[2011,12,4]],"date-time":"2011-12-04T09:08:35Z","timestamp":1322989715000},"page":"e281-e287","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":21,"title":["Gram-negative periodontal pathogens and bacterial endotoxin in metallic orthodontic brackets with or without an antimicrobial agent: An in-vivo study"],"prefix":"10.1016","volume":"140","author":[{"given":"Paulo","family":"Nelson-Filho","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Remberto Marcelo Argando\u00f1a","family":"Valdez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcela Cristina Dami\u00e3o","family":"Andrucioli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Concei\u00e7\u00e3o Pereira","family":"Saraiva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Magda","family":"Feres","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos Art\u00e9rio","family":"Sorgi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucia Helena","family":"Faccioli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ajodo.2011.06.026_bib1","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1016\/j.ajodo.2004.04.017","article-title":"Clinical and microbiologic changes after removal of orthodontic appliances","volume":"126","author":"Sallum","year":"2004","journal-title":"Am J Orthod Dentofacial Orthop"},{"key":"10.1016\/j.ajodo.2011.06.026_bib2","first-page":"260","article-title":"Prevalence of putative periodontopathogens in subgingival dental plaques from gingivitis lesions in Korean orthodontic patients","volume":"43","author":"Lee","year":"2005","journal-title":"J Microbiol"},{"key":"10.1016\/j.ajodo.2011.06.026_bib3","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1111\/j.1600-051X.1998.tb02419.x","article-title":"Microbial complexes in subgingival plaque","volume":"25","author":"Socransky","year":"1998","journal-title":"J Clin Periodontol"},{"key":"10.1016\/j.ajodo.2011.06.026_bib4","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1111\/j.1399-302X.2007.00411.x","article-title":"Microbial complexes in supragingival plaque","volume":"23","author":"Haffajee","year":"2008","journal-title":"Oral Microbiol Immunol"},{"issue":"26","key":"10.1016\/j.ajodo.2011.06.026_bib5","first-page":"16","article-title":"Epidemiology of periodontal disease in children and adolescents","volume":"2001","author":"Jenkins","year":"2000","journal-title":"Periodontol"},{"key":"10.1016\/j.ajodo.2011.06.026_bib6","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1038\/scientificamerican0892-54","article-title":"Bacterial endotoxins","volume":"267","author":"Rietschel","year":"1992","journal-title":"Sci Am"},{"key":"10.1016\/j.ajodo.2011.06.026_bib7","doi-asserted-by":"crossref","first-page":"694","DOI":"10.1097\/00004770-200210000-00004","article-title":"Radiographic evaluation of the effect of endotoxin (LPS) plus calcium hydroxide on apical and periapical tissues of dogs","volume":"28","author":"Nelson-Filho","year":"2002","journal-title":"J Endod"},{"key":"10.1016\/j.ajodo.2011.06.026_bib8","doi-asserted-by":"crossref","first-page":"1950","DOI":"10.1902\/jop.2005.76.11.1950","article-title":"The expression profile of lipopolysaccharide-binding protein, membrane-bound CD14, and toll-like receptors 2 and 4 in chronic periodontitis","volume":"76","author":"Ren","year":"2005","journal-title":"J Periodontol"},{"key":"10.1016\/j.ajodo.2011.06.026_bib9","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1902\/jop.2007.060321","article-title":"Actinobacillus actinomycetemcomitans lipopolysaccharide-mediated experimental bone loss model for aggressive periodontitis","volume":"78","author":"Rogers","year":"2007","journal-title":"J Periodontol"},{"key":"10.1016\/j.ajodo.2011.06.026_bib10","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1111\/j.1399-302X.2008.00475.x","article-title":"Nitric oxide production by a human osteoblast cell line stimulated with Aggregatibacter actinomycetemcomitans lipopolysaccharide","volume":"24","author":"Sosroseno","year":"2009","journal-title":"Oral Microbiol Immunol"},{"key":"10.1016\/j.ajodo.2011.06.026_bib11","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1016\/S0889-5406(99)70288-X","article-title":"Endotoxin affinity for orthodontic brackets","volume":"115","author":"Knoernschild","year":"1999","journal-title":"Am J Orthod Dentofacial Orthop"},{"key":"10.1016\/j.ajodo.2011.06.026_bib12","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1016\/0022-3913(88)90250-8","article-title":"Comparison of the antimicrobial capability of an abrasive paste and chemical-soak denture cleaners","volume":"60","author":"Dills","year":"1988","journal-title":"J Prosthet Dent"},{"key":"10.1016\/j.ajodo.2011.06.026_bib13","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1016\/j.jdent.2011.05.001","article-title":"Use of the checkerboard DNA-DNA hybridisation technique for in vivo detection of cariogenic microorganisms on metallic brackets, with or without use of an antimicrobial agent","volume":"39","author":"Nelson-Filho","year":"2011","journal-title":"J Dent"},{"key":"10.1016\/j.ajodo.2011.06.026_bib14","doi-asserted-by":"crossref","first-page":"705.e11","DOI":"10.1016\/j.ajodo.2006.09.042","article-title":"In-vivo evaluation of the bacterial contamination and disinfection of acrylic baseplates of removable orthodontic appliances","volume":"131","author":"Lessa","year":"2007","journal-title":"Am J Orthod Dentofacial Orthop"},{"key":"10.1016\/j.ajodo.2011.06.026_bib15","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1016\/j.ajodo.2007.10.024","article-title":"Effect of chlorhexidine varnish application on mutans streptococci counts in orthodontic patients","volume":"133","author":"Derks","year":"2008","journal-title":"Am J Orthod Dentofacial Orthop"},{"key":"10.1016\/j.ajodo.2011.06.026_bib16","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/S0887-2333(01)00020-0","article-title":"Mechanisms underlying chlorhexidine induced cytotoxicity","volume":"15","author":"Hidalgo","year":"2001","journal-title":"Toxicol In\u00a0Vitro"},{"key":"10.1016\/j.ajodo.2011.06.026_bib17","first-page":"5","article-title":"Chlorhexidine","volume":"50","author":"Moshrefi","year":"2002","journal-title":"J West Soc Periodontol Periodontal Abstr"},{"key":"10.1016\/j.ajodo.2011.06.026_bib18","doi-asserted-by":"crossref","first-page":"882","DOI":"10.1016\/j.ajodo.2006.07.027","article-title":"Quantitative analysis of adhesion of cariogenic streptococci to orthodontic raw materials","volume":"133","author":"Lim","year":"2008","journal-title":"Am J Orthod Dentofacial Orthop"},{"key":"10.1016\/j.ajodo.2011.06.026_bib19","doi-asserted-by":"crossref","first-page":"121","DOI":"10.3109\/00016356408993968","article-title":"Periodontal disease in pregnancy. II. Correlation between oral hygiene and periodontal condition","volume":"22","author":"Silness","year":"1964","journal-title":"Acta Odontol Scand"},{"key":"10.1016\/j.ajodo.2011.06.026_bib20","first-page":"788","article-title":"\u201cCheckerboard\u201d DNA-DNA hybridization","volume":"17","author":"Socransky","year":"1994","journal-title":"Biotechniques"},{"key":"10.1016\/j.ajodo.2011.06.026_bib21","first-page":"338","article-title":"Microbial profile on metallic and ceramic bracket materials","volume":"72","author":"Anhoury","year":"2002","journal-title":"Angle Orthod"},{"issue":"6 Suppl 1","key":"10.1016\/j.ajodo.2011.06.026_bib22","doi-asserted-by":"crossref","first-page":"S8","DOI":"10.1186\/1472-6831-6-S1-S8","article-title":"Delivery challenges for fluoride, chlorhexidine and xylitol","volume":"15","author":"Featherstone","year":"2006","journal-title":"BMC Oral Health"}],"container-title":["American Journal of Orthodontics and Dentofacial Orthopedics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0889540611007244?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0889540611007244?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T08:52:07Z","timestamp":1760172727000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0889540611007244"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,12]]},"references-count":22,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2011,12]]}},"alternative-id":["S0889540611007244"],"URL":"https:\/\/doi.org\/10.1016\/j.ajodo.2011.06.026","relation":{},"ISSN":["0889-5406"],"issn-type":[{"value":"0889-5406","type":"print"}],"subject":[],"published":{"date-parts":[[2011,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Gram-negative periodontal pathogens and bacterial endotoxin in metallic orthodontic brackets with or without an antimicrobial agent: An in-vivo study","name":"articletitle","label":"Article Title"},{"value":"American Journal of Orthodontics and Dentofacial Orthopedics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajodo.2011.06.026","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2011 American Association of Orthodontists. Published by Mosby, Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}